دانلود مقالات ISI درباره مدل های in vitro + ترجمه فارسی

An Adsorption Chromatography Assay to Probe Bulk Particle Transport Through Hydrogels

Keywords: مدل های in vitro; adsorption; permeability; diffusion; in vitro models; mucosal delivery; hydrogels;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

A flow system for the on-line quantitative measurement of the retention of dosage forms on biological surfaces using spectroscopy and image analysis

Keywords: مدل های in vitro; Bioadhesion; Mucoadhesion; Image analysis; UV/vis spectroscopy; In vitro models; Residence time; Drug delivery;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

An overview: In vitro models of HCV replication in different cell cultures

Keywords: مدل های in vitro; In vitro models; HCV replication; Cell culture;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Evaluation of air-interfaced Calu-3 cell layers for investigation of inhaled drug interactions with organic cation transporters in vitro

Keywords: مدل های in vitro; OCT; organic cation transporters; PKPD; pharmacokinetic/pharmacodynamic; NHBE; normal human bronchial epithelial; RT-PCR; reverse transcriptase polymerase chain reaction; TEER; transepithelial electrical resistance; ASP+; 4-(4-(diethylamino)styryl)-N-meth

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

A pro-convulsive carbamazepine metabolite: Quinolinic acid in drug resistant epileptic human brain

Keywords: مدل های in vitro; Blood–brain barrier; Drug resistance; Drug metabolism; Drug delivery; Carbamazepine; Pharmacokinetics; In vitro models; Tissue engineering; Neurotoxicity; Pharmacogenomics

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Evaluation of layers of the rat airway epithelial cell line RL-65 for permeability screening of inhaled drug candidates

Keywords: مدل های in vitro; In vitro models; Pulmonary delivery; Drug inhalation; Absorption prediction; Drug transporters; In vitro/in vivo correlation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Relevance and challenges in modeling human gastric and small intestinal digestion

Keywords: مدل های in vitro; human digestion; stomach and small intestine; in vitro models

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Naltrexone Salt Selection for Enhanced Transdermal Permeation Through Microneedle-Treated Skin

Keywords: مدل های in vitro; transdermal drug delivery; microneedles; naltrexone; salts; skin; in vitro models; diffusion; permeability; solubility;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Differential Selectivity of Efflux Transporter Inhibitors in Caco-2 and MDCK-MDR1 Monolayers: A Strategy to Assess the Interaction of a New Chemical Entity with P-gp, BCRP, and MRP2

Keywords: مدل های in vitro; ABC transporters; MDCK cells; active transport; Caco-2 cells; transporters; P-glycoprotein; membrane transporter; in vitro models; intestinal absorption; multidrug resistance transporters;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

An Intravaginal Ring for the Simultaneous Delivery of Multiple Drugs

Keywords: مدل های in vitro; drug delivery systems; HIV/AIDS; formulation; in vitro models; mechanical properties; intravaginal ring; microbicide delivery; silicone; sustained release; combination delivery device;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Lipid Nanoparticles as Carrier for Octyl-Methoxycinnamate: In Vitro Percutaneous Absorption and Photostability Studies

Keywords: مدل های in vitro; Nanoparticles; Percutaneous; Photodegradation; Calorimetry (DSC); In vitro models; Skin; Particle size; Ultrasound;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Use of Enzyme Inhibitors to Evaluate the Conversion Pathways of Ester and Amide Prodrugs: A Case Study Example with the Prodrug Ceftobiprole Medocaril

Keywords: مدل های in vitro; prodrug; drug metabolizing enzymes; in vitro models; inhibition; enzymology; hydrolysis; conversion; paraoxonase; esterase; ceftobiprole;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Influence of Lipid Composition and Drug Load on the In Vitro Performance of Self-Nanoemulsifying Drug Delivery Systems

Keywords: مدل های in vitro; self-nanoemulsiying drug delivery system (SNEDDS); lipids; drug load; lipid chain length; in vitro models; oral drug delivery; dispersion; precipitation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

A comparison of two human cell lines and two rat gonadal cell primary cultures as in vitro screening tools for aromatase modulation

Keywords: مدل های in vitro; Endocrine disrupting chemicals; Aromatase; In vitro models; Risk assessment; Toxicity;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Microfabrication technologies for oral drug delivery

Keywords: مدل های in vitro; Microfabrication; Microdevices; Microfluidics; Oral drug delivery; Oral absorption; In vitro models

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Transport of a Lipophilic Ionizable Permeant (Capric Acid) Across a Lipophilic Membrane (Silicone Polymer Membrane) from Aqueous Buffered Solutions in the Presence of Hydroxypropyl-β-Cyclodextrin

Keywords: مدل های in vitro; absorption enhancer; cyclodextrins; drug transport; solubility; permeability; absorption; in vitro models; membrane transport; transport;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Suitability of Isolated Rat Jejunum Model for Demonstration of Complete Absorption in Humans for BCS-Based Biowaiver Request

Keywords: مدل های in vitro; absorption; Biopharmaceutics Classification System; in vitro models; intestinal absorption; permeability; isolated rat jejunum;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Active Compounds Release from Semisolid Dosage Forms

Keywords: مدل های in vitro; active transport; controlled release; diffusion; emulsions; formulation; gels; kinetics; in vitro models;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

The Effects of Media on Pharmaceutically Relevant Transporters in the Human HT-29 Adenocarcinoma Cell Line: Does Culture Media Need to be Controlled?

Keywords: مدل های in vitro; Caco-2 cells; peptide drug delivery; drug transport; in vitro models; transporters; peptide transporters; polymerase chain reaction; solute transporters; ABC transporters; permeability;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

In Vitro Blood-Brain Barrier Models: Current and Perspective Technologies

Keywords: مدل های in vitro; in vitro models; blood-brain barrier; cell culture; CNS; endothelial; passive diffusion/transport; tight junction; alternative research;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2012 سفارش ترجمه

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 1: Method Parameterization and Comparison of In Vitro Digestion Profiles Across a Range of Representative Formulations

Keywords: مدل های in vitro; LFCS Consortium; lipid-based drug delivery systems; SEDDS; drug solubilization; in vitro digestion testing; Solubility; Biopharmaceutics classification system (BCS); Bioavailability; In vitro models; Precipitation

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2012 سفارش ترجمه

Development of an in vitro exposure model for investigating the biological effects of therapeutic aerosols on human cells from the respiratory tract

Keywords: مدل های in vitro; CULTEX®; COPD; Asthma; In vitro models; Direct exposure; Air–liquid interface

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Effect of Knockdown of Ezrin, Radixin, and Moesin on P-Glycoprotein Function in HepG2 Cells

Keywords: مدل های in vitro; P‐glycoprotein; ABC transporters; cancer; efflux pumps; in vitro models;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Substrate- and Species-dependent Inhibition of P-glycoprotein-mediated Transport: Implications for Predicting in vivo Drug Interactions

Keywords: مدل های in vitro; Drug interactions; In vitro models; P‐glycoprotein; substrate‐dependent; flow‐cytometry; species‐dependent;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

In vitro and in vivo characteristics of celecoxib in situ formed suspensions for intra-articular administration

Keywords: مدل های in vitro; controlled release; formulation vehicle; injectables; in vitro models; precipitation; solid state; suspensions;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Peptide Transporter 1 Is Responsible for Intestinal Uptake of the Dipeptide Glycylsarcosine: Studies in Everted Jejunal Rings from Wild-type and Pept1 Null Mice

Keywords: مدل های in vitro; in vitro models; intestinal absorption; membrane transport/transporters; peptide transporters; pharmacokinetics; transgenics;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Development of a Polymeric Patch Impregnated with Naproxen as a Model of Transdermal Sustained Release System

Keywords: مدل های in vitro; controlled delivery; transdermal drug delivery; processing; in vitro models; polymeric drug carrier; supercritical fluids;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Mathematical modeling of variables involved in dissolution testing

Keywords: مدل های in vitro; variables; dissolution testing; dissolution rate; in vitro models; mathematical model;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

6-Mercaptopurine Transport by Equilibrative Nucleoside Transporters in Conditionally Immortalized Rat Syncytiotrophoblast Cell Lines TR-TBTs

Keywords: مدل های in vitro; placenta; drug transport; in vitro models; pharmacokinetics; nucleoside transporters; organic anion transporters; multidrug resistance-associated proteins

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Molecular mechanisms for insulin resistance in treated HIV-infection

Keywords: مدل های in vitro; insulin sensitivity; glucose transport; in vitro models; HIV protease inhibitors; nucleoside reverse transcriptase inhibitors; adipocytokines; ER stress; lipotoxicity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Development of a taste-masked generic ibuprofen suspension: Top-down approach guided by electronic tongue measurements

Keywords: مدل های in vitro; pediatric; formulation; analysis; excipients; in vitro models; multivariate analysis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Establishment of In Vitro P-Glycoprotein Inhibition Assay and Its Exclusion Criteria to Assess the Risk Of Drug–Drug Interaction at the Drug Discovery Stage

Keywords: مدل های in vitro; P-glycoprotein; in vitro models; P-gp inhibition; transporters; digoxin; drug interactions; difference of IC50 values; mathematical model; risk assessment for DDI; pharmacokinetics

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Development of a new permeability assay using low‐efflux MDCKII cells

Keywords: مدل های in vitro; absorption; P‐glycoprotein; ADME; drug transport; in vitro models; bioavailability; LC-MS; Biopharmaceutics Classification System (BCS); cell culture; MDCK cells; transporters;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Functional characterization of Rat Plasma Membrane Monoamine Transporter in the Blood–Brain and Blood–Cerebrospinal Fluid Barriers

Keywords: مدل های in vitro; blood–brain barrier; blood–cerebrospinal fluid barrier; in vitro models; transporters; CNS; plasma membrane monoamine transporter; 1-methyl-4-phenylpyridinium; TR-BBB13 cells; TR-CSFB3 cells

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Skin tissue engineering — In vivo and in vitro applications

Keywords: مدل های in vitro; Tissue engineering; Extracellular matrix; Skin; In vitro models; Keratinocytes; Melanocytes

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

MRI Studies of the Hydrodynamics in a USP 4 Dissolution Testing Cell

Keywords: مدل های in vitro; hydrodynamics; USP apparatus 4 (flow-through cell); magnetic resonance imaging (MRI); dissolution testing; laminar flow; physical characterization; in vitro models; dissolution; in vitro-in vivo correlations (IVIVC); controlled release;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 2: Comparative assessment of prediction methods of human volume of distribution

Keywords: مدل های in vitro; volume of distribution at steady state; pharmacokinetics; protein binding; computational ADME; first-time-in-human; in vitro models; distribution; allometry;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

A Review of Three-Dimensional In Vitro Tissue Models for Drug Discovery and Transport Studies

Keywords: مدل های in vitro; in vitro models; tissue engineering; transport; cancer; cell culture

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

Tracking protein electrodenaturation fronts in the electrochemical treatment of tumors

Keywords: مدل های in vitro; Tumors; Electrochemical treatment; In vitro models; Electrodenaturation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Animal models of traumatic brain injury: Is there an optimal model to reproduce human brain injury in the laboratory?

Keywords: مدل های in vitro; Model of brain injury; Diffuse injury; Focal injury; Rodents; In vitro models;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Hyaluronic acid signals for repair in ethanol-induced apoptosis in skin cells in vitro

Keywords: مدل های in vitro; Apoptosis; A431 epidermoid skin cells; Mouse fibroblasts; Interferon alpha; Tumor necrosis factor alpha; Ethanol; Hyaluronic acid; In vitro models; Transmission electron microscopy

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Electrochemical treatment of tumors using a one-probe two-electrode device

Keywords: مدل های in vitro; Tumors; Electrochemical treatment; Electrochemotherapy; pH front tracking; In vitro models

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Interstrain Differences of In Vitro Metabolic Stability and Impact on Early Drug Discovery

Keywords: مدل های in vitro; ADME; high-performance/pressure liquid chromatography (HPLC); microsomes; mass spectrometry; in vitro models; metabolic clearance; cytochrome P450; phase I metabolism;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Propagation of Uncertainty in Nasal Spray In Vitro Performance Models Using Monte Carlo Simulation: Part II. Error Propagation During Product Performance Modeling

Keywords: مدل های in vitro; factorial design; in vitro models; mathematical model; Monte Carlo; nasal drug delivery; drug design;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Relative Bioavailability of Three Different Solid Forms of PNU-141659 as Determined with the Artificial Stomach-Duodenum Model

Keywords: مدل های in vitro; dissolution; in vitro models; preformulation; polymorphism; amorphous; hydrate

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Evaluation of active and passive transport processes in corneas extracted from preserved rabbit eyes

Keywords: مدل های in vitro; in vitro models; paracellular transport; permeability; tight junction; transcellular transport; transporters;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Improved Method for Determining Partition and Diffusion Coefficients in Human Dermis

Keywords: مدل های in vitro; albumin; diffusion; drug transport; in vitro models; passive diffusion/transport; permeability; protein binding; membrane transport; skin; tissue partition;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Prediction of In Vivo Enantiomeric Compositions by Modeling In Vitro Metabolic Profiles

Keywords: مدل های in vitro; ADME; chirality; metabolism; enzyme kinetics; in vitro models; kinetics; microsomes; pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Analysis of Unstirred Water Layer in In Vitro Permeability Experiments

Keywords: مدل های in vitro; absorption; Caco-2 cells; diffusion; intestinal absorption; in vitro models;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

A Novel Flow through Diffusion Cell for Assessing Drug Transport across the Buccal Mucosa In Vitro

Keywords: مدل های in vitro; absorption; buccal mucosa; epithelial permeability; flow through; in vitro models; salmeterol xinafoate; transmucosal drug delivery;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه