Keywords: آنزیم مورد نیاز inositol 1; Arsenic; Autophagy inhibitor; ER stress; Proteostasis; Oxidative stress; ATF6; activating transcription factor 6; DCF; 2â²,7â²-dichlorofluorescein; H2DCFDA; 2â²,7â²-dichlorodihydrofluorescein diacetate; EIF2S1/eIF2α; eukaryotic initiation factor 2, s
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Keywords: آنزیم مورد نیاز inositol 1; A-type EGCG dimer; Lead; Liver; Insulin resistance; ER stress; Apoptosis; AEd; A-type dimeric epigallocatechin-3-gallate; AKT; phosphorylated protein kinase B; CHOP; C/EBP homologous protein; EGCG; epigallocatechin-3-gallate; G6Pase; cytoplasmic glucose-6
Keywords: آنزیم مورد نیاز inositol 1; CNS; central nervous system; ER; endoplasmic reticulum; Hcy; homocysteine; tHcy; total fasting homocysteine; HHcy; hyperhomocysteinemia; CBS; cystathionine β-synthase; BHMT; betaine methyltransferase; UPR; unfolded protein response; MTHFR; methylene tetr
Keywords: آنزیم مورد نیاز inositol 1; AAA; ATPases associated with diverse cellular activities; 17-AAG; 17-N-allylamino-17-demethoxygeldanamycin; ABC; ATP-binding cassette; ABCE1; ATP binding cassette subfamily E member 1; AD; Alzheimer's disease; AIF; apoptosis inducing factor; Akt; Alpha se
Keywords: آنزیم مورد نیاز inositol 1; ER; endoplasmic reticulum; THG; thapsigargin; PDI; protein disulfide isomerase; TMX; thioredoxin-related-transmembrane proteins; UPR; unfolded protein response; PERK; pancreatic ER kinase PKR-like ER kinase; ATF6; activating transcription factor-6; IRE1;
Keywords: آنزیم مورد نیاز inositol 1; ATF4; activating transcription factor-4; ATF6; activating transcription factor-6; CHOP; CCAAT/enhancer binding protein-homologous protein; cyt c; cytochrome c; eIF2α; eukaryotic translation initiation factor-2α; ER stress; endoplasmic reticulum stress;
Keywords: آنزیم مورد نیاز inositol 1; ATF6; activating transcription factor 6; CHOP; C/EBP homologous protein; CNS; central nervous system; ER; endoplasmic reticulum; ERS; endoplasmic reticulum stress; GRP78; 78-kDa glucose-regulated protein; IRE1; inositol-requiring enzyme 1; JNK; c-JUN NH2-
Keywords: آنزیم مورد نیاز inositol 1; ANOVA; analysis of variance; ATF-4; activating transcription factor-4; ATF-6; activating transcription factor-6; C/EBP; CCAAT/enhancer-binding protein; CHOP; C/EBP homologous protein; eIf2α; eukaryotic translation initiation factor 2 subunit α; ER; endo
Keywords: آنزیم مورد نیاز inositol 1; ASK1; apoptosis signal-regulating kinase 1; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; Bcl-2; B-cell lymphoma 2; BiP; binding immunoglobulin protein; bZIP; basic leucine zipper; CDK; cyclin-dependent kinase; CDKI; CD
ROS mediated ER stress induces Bax-Bak dependent and independent apoptosis in response to Thioridazine
Keywords: آنزیم مورد نیاز inositol 1; MEF; mouse embryonic fibroblast; UPR; unfolded protein response; ER; endoplasmic reticulum; DKO; double knock out; ROS; reactive oxygen species; GFP; green fluorescent protein; Bcl-2; B-cell lymphoma 2; Bax; Bcl-2 associated X protein; Bak; Bcl-2 antagoni
Inositol-requiring enzyme 1 involved in regulating hemocyte apoptosis upon heat stress in Patinopecten yessoensis
Keywords: آنزیم مورد نیاز inositol 1; Patinopecten yessoensis; Inositol-requiring enzyme 1; Heat stress; Apoptosis; Unfolded protein response;
CREB element is essential for unfolded protein response (UPR) mediating the Cu-induced changes of hepatic lipogenic metabolism in Chinese yellow catfish (Pelteobagrus fulvidraco)
Keywords: آنزیم مورد نیاز inositol 1; ACC; Acetyl-CoA carboxylase; CREB; cAMP-response element binding protein; ATF6; Activating transcription factor 6; ER; endoplasmic reticulum; ERSE; ER stress response element; FAS; Fatty acid synthase; GRP78/BiP; 78-kDa glucose-regulated protein; IRE1; In
Loss of C/EBP-β LIP drives cisplatin resistance in malignant pleural mesothelioma
Keywords: آنزیم مورد نیاز inositol 1; ANOVA; analysis of variance; ATF6; activating transcription factor 6; C/EBP; CAAT/enhancer binding protein; IRE1; inositol-requiring enzyme 1; CHOP/GADD153; C/EBP homologous protein/growth arrest/DNA damage inducible 153; CEA; carcino-embrionic antigen; C
Protein tyrosine phosphatase 1B regulates endothelial endoplasmic reticulum stress; role in endothelial dysfunction
Keywords: آنزیم مورد نیاز inositol 1; Shear stress; Nitric oxide; Protein kinase RNA-like endoplasmic reticulum kinase; Mesenteric resistance artery; Ach; Acetylcholine; ATF6; Activated Transcription Factor 6; BAX; Bcl-2-Associated X Protein; BCL2; B-Cell Lymphoma 2; CHOP; C/EBP Homologous
Gap junctional intercellular communication and endoplasmic reticulum stress regulate chronic cadmium exposure induced apoptosis in HK-2 cells
Keywords: آنزیم مورد نیاز inositol 1; AKT; protein kinase B; ASK1; apoptosis signal-regulating kinase 1; ER; endoplasmic reticulum; GJIC; gap junctional intercellular communication; IRE1α; inositol-requiring enzyme 1; ROS; reactive oxygen species; UPR; unfolded protein response; XBP-1s; spli
Curcumin induces osteoblast differentiation through mild-endoplasmic reticulum stress-mediated such as BMP2 on osteoblast cells
Keywords: آنزیم مورد نیاز inositol 1; ER; endoplasmic reticulum; BMP; bone morphogenetic protein; Runx2; Runt-related transcription factor 2; OC; osteocalcin; UPR; unfolded protein response; PERK; PKR-like endoplasmic reticulum kinase; IRE-1; inositol-requiring enzyme 1; ATF; activating trans
Amyloid toxicity is enhanced after pharmacological or genetic invalidation of the Ï1 receptor
Keywords: آنزیم مورد نیاز inositol 1; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP; amyloid precursor protein; Aβ25-35; amyloid-β[25-35] peptide; BDNF; brain-derived neurotrophic factor; BiP; 78 kDa glucose-regulated protein; cAMP; cyclic adenosine monophosphate; CREB;
Novel oxindole derivatives prevent oxidative stress-induced cell death in mouse hippocampal HT22â¯cells
Keywords: آنزیم مورد نیاز inositol 1; ER stress; Ferroptosis; Oxidative stress; Oxindole; Oxytosis; Rasagiline; ATF6; activated transcription factor 6; ARE; antioxidant response element; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; Grp78; 78-kDa glucose-regulated prote
Portal myofibroblasts are sensitive to CCN-mediated endoplasmic reticulum stress-related apoptosis with potential to attenuate biliary fibrogenesis
Keywords: آنزیم مورد نیاز inositol 1; CCN proteins; ER stress; Unfolded protein response; Matricellular proteins; Portal myofibroblasts; TUDCA; α-SMA; α-smooth muscle actin; ATF6; activating transcription factor 6; BDL; bile duct ligation; eIF2α; eukaryotic translation initiation factor 2Î
Cartilage oligomeric matrix protein: COMPopathies and beyond
Keywords: آنزیم مورد نیاز inositol 1; ATF6; activating transcription factor 6; ATP; adenosine triphosphate; BiP; binding immunoglobulin protein; BMD; bone mineral density; Chop; Mouse c/ebp homologous protein genes; CHOP; c/ebp homologous protein; COL9A1; human collagen type 9 Alpha 1 chain g
UPR activation specifically modulates glutamate neurotransmission in the cerebellum of a mouse model of autism
Keywords: آنزیم مورد نیاز inositol 1; NLGN3; neuroligin3; ASDs; autism spectrum disorders; UPR; unfolded protein response; ER; endoplasmic reticulum; WT; wild type; mEPSC; miniature excitatory post-synaptic currents; DMSO; dimethyl sulfoxide; ATF6; activating transcription factor 6; BiP; immu
The innate immune response to RSV: Advances in our understanding of critical viral and host factors
Keywords: آنزیم مورد نیاز inositol 1; ATF6; activated transcription factor 6; BAP31; B-cell receptor-associated protein 31; Bcl2; B-cell lymphoma 2; DR4/5; death receptor 4/5; DUOX2; dual oxidase 2; DVGs; defective viral genomes; IB; inclusion body; IFIT1; interferon-induced protein with tetr
Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation
Keywords: آنزیم مورد نیاز inositol 1; AMPK; AMP-activated protein kinase; ATF4; Activating Transcription Factor 4; ATF6; Activating Transcription Factor 6; BAF; Bafilomycin A1; BiP (GRP78); Binding immunoglobulin Protein (78Â kDa glucose regulated protein); BZ; bortezomib; CHOP; C/EBP-Homolog
Downregulation of TRB3 protects neurons against apoptosis induced by global cerebral ischemia and reperfusion injury in rats
Keywords: آنزیم مورد نیاز inositol 1; ANOVA; analysis of variance; ATF4; transcription factor 4; Bad; Bcl-2-associated death protein; BCA; bicinchoninic acid assay; CA; cornu ammonis; CHOP; CCAAT/enhancer-binding protein (C/EBP) homologous protein; DAB; diaminobenzidine; DAPI; 4,6,diamidino-2
Taraxacum mongolicum extract induced endoplasmic reticulum stress associated-apoptosis in triple-negative breast cancer cells
Keywords: آنزیم مورد نیاز inositol 1; TNBC; Triple-negative breast cancer; ER; endoplasmic reticulum; UPR; unfolded protein response; IRE1; inositol-requiring enzyme 1; PERK; protein kinase R-like ER kinase; ATF6; activating transcription factor 6; DMSO; dimethyl sulfoxide; MTT: 3-(4; 5-dimet
Both nitric oxide and nitrite prevent homocysteine-induced endoplasmic reticulum stress and subsequent apoptosis via cGMP-dependent pathway in neuronal cells
Keywords: آنزیم مورد نیاز inositol 1; Nitric oxide; Nitrite; Endoplasmic reticulum stress; Apoptosis; cGMP; Neuronal cells; 7-AAD; 7-aminoactinomycin D; AD; Alzheimer's disease; ATF6; activating transcription factor 6; Br-cGMP; 8-bromo-cyclic cyclic guanosine 3â²,5â²-monophosphate; cGMP; cy
HSPA5 Gene encoding Hsp70 chaperone BiP in the endoplasmic reticulum
Keywords: آنزیم مورد نیاز inositol 1; aa; amino acid; ATF6; activating transcription factor 6; BIK; BCL2-interacting killer; BiP; binding immunoglobulin protein; CD86; cluster of differentiation 86; CHOP; CCAAT-enhancer-binding protein homologous protein; Derlin-1; degradation in ER protein 1
ER stress disturbs SR/ER-mitochondria Ca2Â + transfer: Implications in Duchenne muscular dystrophy
Keywords: آنزیم مورد نیاز inositol 1; ATF6; activating transcription factor 6; ATP; Adenosine triphosphate; CTL; Control; Ddit3; DNA damage inducible transcript 3; DMD; Duchenne Muscular Dystrophy; EDL; Extensor Digitorum Longus; EIF2α; eukaryotic translation initiation factor 2A; FBS; fetal
Tetramethylpyrazine suppresses angiotensin II-induced soluble epoxide hydrolase expression in coronary endothelium via anti-ER stress mechanism
Keywords: آنزیم مورد نیاز inositol 1; AUDA; 12-[[(tricyclo[3.3.1.13,7]dec-1ylamino)carbonyl]amino]dodecanoic acid; 4-PBA; 4-phenylbutyric acid; GRP78; 78-kDa glucose-regulated protein; ATF6; Activating transcription factor 6; Ang-II; Angiotensin-II; CYP; Cytochrome P450; ER stress; Endoplasmi
The roles of subcellularly located EGFR in autophagy
Keywords: آنزیم مورد نیاز inositol 1; AMPK; AMP-activated protein kinase; ATG; autophagy-related; BCL2; B-cell lymphoma 2; BCL2L1; BCL2 like 1; BNIP3; BCL2/Adenovirus E1B-binding protein Nip3; CME; clathrin-mediated endocytosis; cytoSTAT3; cytoplasmic STAT3; Dsbs; double strand breaks; ECD; e
Activating transcription factor 6-dependent sestrin 2 induction ameliorates ER stress-mediated liver injury
Keywords: آنزیم مورد نیاز inositol 1; Ad; adenovirus; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ATF6; activating transcription factor 6; ChIP; chromatin immunoprecipitation; CHOP; C/EBP homologous protein; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxid
The regulation of cellular apoptosis by the ROS-triggered PERK/EIF2α/chop pathway plays a vital role in bisphenol A-induced male reproductive toxicity
Keywords: آنزیم مورد نیاز inositol 1; AIF; apoptosis-inducing factor; ATF6; activating transcription factor 6; BPA; bisphenol A; CHOP; CCAAT/enhancer-binding protein-homologous protein; Cyt-c; cytochrome complex; EdU; 5-ethynyl-2â²-deoxyuridine; EIF2α; eukaryotic initiation factor 2 α; ER;
Astemizole-Histamine induces Beclin-1-independent autophagy by targeting p53-dependent crosstalk between autophagy and apoptosis
Keywords: آنزیم مورد نیاز inositol 1; AST; Astemizole; HIS; Histamine; H1R; Histamine H1 receptor; ROS; Reactive oxygen species; ER; Endoplasmic reticulum; PERK; Protein kinase R-like endoplasmic reticulum kinase; IRE1α; Inositol-requiring enzyme 1; ATF; Activating transcription factor; JNK;
Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells
Keywords: آنزیم مورد نیاز inositol 1; 4E-BP1; 4E binding protein; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; ATP; adenosine triphosphate; DEPTOR; DEP domain containing mTOR-interacting protein; CI; complexes I; CII; complex II; CIII; complex III; CIV; complex
Suppression of StarD7 promotes endoplasmic reticulum stress and induces ROS production
Keywords: آنزیم مورد نیاز inositol 1; BSA; bovine serum albumin; CHX; cycloheximide; DMSO; dimethyl sulfoxide; ER; endoplasmic reticulum; eIF2α; eukaryotic translation initiation factor 2, subunit 1α; GRP78/BiP; glucose regulated protein 78/immunoglobulin heavy chain-binding protein; H2DCFD
Adenoviral CCN gene transfers induce in vitro and in vivo endoplasmic reticulum stress and unfolded protein response
Keywords: آنزیم مورد نیاز inositol 1; Ad-CCN1-4; Ad5-CMV-CCN1-4; Ad-Luc; Ad5-CMV-Luc; ATF6; activating transcription factor 6; β-Gal; β-galactosidase; BDL; bile duct ligation; ECM; extracellular matrix; ER; endoplasmic reticulum; ERAD; ER-associated protein degradation; h; human; HSC; h
A novel mutation in PNLIP causes pancreatic triglyceride lipase deficiency through protein misfolding
Keywords: آنزیم مورد نیاز inositol 1; BiP; immunoglobulin binding protein; ER; endoplasmic reticulum; GRP94; glucose-regulated protein-94; IRE1; inositol-requiring enzyme 1; PNLIP; pancreatic triglyceride lipase; PNLIPRP2; pancreatic lipase related protein 2; XBP1; X-box binding protein-1; Li
Disruption of the unfolded protein response (UPR) by lead compound selectively suppresses cancer cell growth
Keywords: آنزیم مورد نیاز inositol 1; Selective cancer therapy; Unfolded protein response; 2DG; UPR disrupter; UPR; unfolded protein response; 2DG; 2-deoxy-D-glucose; IRE1; inositol-requiring enzyme 1; XBP1; X-box binding protein 1; GRP78; glucose-regulated protein 78âkDa; TM; tunicamycin;
Amyloidogenic lysozymes accumulate in the endoplasmic reticulum accompanied by the augmentation of ER stress signals
Keywords: آنزیم مورد نیاز inositol 1; Armet; arginine-rich, mutated in early stage tumors; ATF4; activating transcription factor 4, a PERK downstream target; ATF6α; activating transcription factor 6α; CHOP; C/EBP homologous protein; DAPI; diamidino-2-phenylindole; EDEM1; ER degradation-enha
Bufotalin-induced apoptosis in osteoblastoma cells is associated with endoplasmic reticulum stress activation
Keywords: آنزیم مورد نیاز inositol 1; ATF6; activating transcription factor 6; CHOP; C/EBP homologous protein; eIF2α; the eukaryotic initiation factor 2α; ER; endoplasmic reticulum; IRE1; inositol-requiring enzyme 1; PERK; double-stranded RNA-activated protein kinase (PKR)-like ER kinase; s
A sensitive assay for the biosynthesis and secretion of MANF using NanoLuc activity
Keywords: آنزیم مورد نیاز inositol 1; Armet; arginine-rich mutated in early stage of tumors; ER; endoplasmic reticulum; GRP78; 78-kDa glucose regulated protein; IRE1; inositol-requiring enzyme 1; MANF; mesencephalic astrocyte-derived neurotrophic factor; NanoLuc; a small nanoluciferase; RT-PC
A calpain-cleaved fragment of β-catenin promotes BCRABL1 + cell survival evoked by autophagy induction in response to imatinib
Keywords: آنزیم مورد نیاز inositol 1; ULK1; unc-51-like kinase; ATG; autophagy-related proteins; FIP200; focal adhesion interacting protein 200; PI3K; class III phosphoinositide 3-kinase; Vps; vacuolar protein sorting; LC3; microtubule-associated protein 1 light chain 3; PE; phosphatidylethan
Role of the ubiquitin-proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice
Keywords: آنزیم مورد نیاز inositol 1; ATF6; activating transcription factor 6; ATGL; adipose triglyceride lipase; AKO; adipose triglyceride lipase knockout; AMC; amino-4-methylcoumarin; CHOP; C/EBP homologous protein; EDTA; ethylenediaminetetraacetic acid; ER; endoplasmic reticulum; FA; fatty
Involvement of ASK1-p38 pathway in the pathogenesis of diabetes triggered by pancreatic à cell exhaustion
Keywords: آنزیم مورد نیاز inositol 1; Ins2; Insulin 2 protein; ER; endoplasmic reticulum; ASK1; apoptosis signal-regulating kinase 1; UPR; unfolded protein response; PERK; protein kinase RNA-like ER kinase; ATF6; activating transcription factor 6; IRE1; inositol-requiring enzyme 1; ERAD; ER-a
Ursolic acid induces ER stress response to activate ASK1-JNK signaling and induce apoptosis in human bladder cancer T24 cells
Keywords: آنزیم مورد نیاز inositol 1; AMPK; AMP-activated protein kinase; ACC; Acetyl-CoA Carboxylase; ASK1; Apoptosis signal regulating kinase 1; ATF6; activating transcription factor 6; CHOP; C/EBP homologous protein; eIF2α; the eukaryotic initiation factor 2α; ELISA; Enzyme-linked immuno
Chibby drives β catenin cytoplasmic accumulation leading to activation of the unfolded protein response in BCR-ABL1 + cells
Keywords: آنزیم مورد نیاز inositol 1; CML; chronic myeloid leukemia; TK; tyrosine kinase; LSC; leukemic stem cell; APC; Adenomatous polyposis coli; GSK3; glycogen synthase kinase 3; CBY; Chibby; TCF; T cell factor; LEF; lymphoid enhancer factor; ER; endoplasmic reticulum; UPR; unfolded protei
Involvement of SIRT1-AMPK signaling in the protective action of indole-3-carbinol against hepatic steatosis in mice fed a high-fat diet
Keywords: آنزیم مورد نیاز inositol 1; I3C; indole-3-carbinol; HFD; high-fat diet; ND; normal diet; SREBP-1c; sterol regulatory element-binding protein-1c; FAS; fatty acid synthase; LPL; lipoprotein lipase; SIRT1; silent mating type information regulation 2 homolog 1; AMPK; AMP-activated prote
Bidirectional regulation of NF-κB by reactive oxygen species: A role of unfolded protein response
Keywords: آنزیم مورد نیاز inositol 1; NF-κB; nuclear factor-κB; UV; ultraviolet; IκB; inhibitor of NF-κB; IKK; IκB kinase; NEMO; NF-κB essential modulator; TNFR; tumor necrosis factor receptor; IL-1R; interleukin-1 receptor; NIK; NF-κB inducing kinase; LPS; lipopolysaccharide; PKD; pro
Regulation of inositol 1,4,5-trisphosphate receptors during endoplasmic reticulum stress
Keywords: آنزیم مورد نیاز inositol 1; a.a.; amino acid; ATF; activating transcription factor; Bcl-2; B-cell lymphoma 2; Bcl-Xl; B-cell lymphoma-extra large; BH3; Bcl-2 homology 3; BI-1; Bax inhibitor-1; BiP; immunoglobulin heavy chain-binding protein; CHOP; C/EBP-homologous protein; CSQ; cals
Inhibition of enterovirus 71 entry by transcription factor XBP1
Keywords: آنزیم مورد نیاز inositol 1; Enterovirus 71; Endoplasmic reticulum stress; Inositol-requiring enzyme 1; Unfolded protein response; Translational attenuation; X-box-binding protein 1