دانلود مقالات ISI درباره IP3، inositol 1،4،5-trisphosphate + ترجمه فارسی

Computational biology analysis of platelet signaling reveals roles of feedbacks through phospholipase C and inositol 1,4,5-trisphosphate 3-kinase in controlling amplitude and duration of calcium oscillations

Keywords: IP3، inositol 1،4،5-trisphosphate; Blood platelet; Calcium signaling; Positive feedback; Negative feedbackPLC, phospholipase С; IP3, inositol 1,4,5-trisphosphate; IP3K, inositol 1,4,5-trisphosphate 3-kinase; DTS, dense tubular system; PS, phosphatidylserine; PAR, protease-activated recepto

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Digitoxin enhances the growth inhibitory effects of thapsigargin and simvastatin on ER negative human breast cancer cells

Keywords: IP3، inositol 1،4،5-trisphosphate; DAG, diacylglycerol; D7, diospyrin diethylether; ER, endoplasmic reticulum; FAP, fibroblast activation protein; HCC, hepatocellular cancer; HMGR, HMG-CoA reductase; IAP, inhibitor of apoptosis; IP3, inositol 1,4,5-trisphosphate; 4NQO, 4-Nitroquinoline 1-o

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Saline and osmotic stresses stimulate PLD/diacylglycerol kinase activities and increase the level of phosphatidic acid and proline in barley roots

Keywords: IP3، inositol 1،4،5-trisphosphate; ABA, abscisic acid; CL, cardiolipin; DAG, diacylglycerol; DAG-k, diacylglycerol kinase; DGPP, diacylglycerol pyrophosphate; DGPPase, diacylglycerol pyrophosphate phosphatase; IAA, indole-3-acetic acid; IP3, inositol 1,4,5-trisphosphate; GA3, gibberellic a

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Neuropharmacological effects of Phoneutria nigriventer venom on astrocytes

Keywords: IP3، inositol 1،4،5-trisphosphate; Arthropod venom; Astrocytes; Ca2+ responses; Stress fibers; TLR4; GlutamateAUC, area under the curve; BBB, blood-brain barrier; Cx43, connexin 43; GFAP, glial fibrillary acidic protein; IL-1β, interleukin-1β; IP3, inositol 1,4,5-trisphosphate; IP3R, inosi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

In vitro and in vivo imaging of intracellular Ca2+ responses in salivary gland cells

Keywords: IP3، inositol 1،4،5-trisphosphate; ACh, acetylcholine; AQP5, aquaporin 5; [Ca2+]i, intracellular Ca2+ concentration; GECI, genetically encoded Ca2+ indicator; IP3, inositol 1,4,5-trisphosphate; mAChR, muscarinic acetylcholine receptor; PG, parotid gland; SMG, submandibular gland; SLG, subl

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Maternal micronutrient imbalance alters gene expression of BDNF, NGF, TrkB and CREB in the offspring brain at an adult age

Keywords: IP3، inositol 1،4،5-trisphosphate; BDNF, brain derived neurotrophic factor; CREB, cAMP response element-binding protein; DAG, diacylglycerol; DHA, docosahexaenoic acid; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; IP3, inositol 1,4,5-trisphosphate; MAPK, mitogen activated protein kinas

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

A fluorescence-based method for evaluating inositol 1,4,5-trisphosphate receptor ligands: Determination of subtype selectivity and partial agonist effects

Keywords: IP3، inositol 1،4،5-trisphosphate; ADA, adenophostin A; IP3, inositol 1,4,5-trisphosphate; IP3R, inositol 1,4,5-trisphosphate receptor; FRET, fluorescence resonance energy transfer; LBD, ligand-binding domain of IP3R; ICM, intracellular-like medium; ECFP, enhanced cyan fluorescent protein;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Broad feedback inhibition of pre-B-cell receptor signaling components

Keywords: IP3، inositol 1،4،5-trisphosphate; pre-BCR, pre-B-cell receptor; SLC, surrogate light chain; IP3, inositol 1,4,5-trisphosphate; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; PLA, proximity ligation assay; CaM, calmodulinPre-BCR; Calcium signaling; Cell proliferation; Gene regulation; E2

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Phospholipase C-β in immune cells

Keywords: IP3، inositol 1،4،5-trisphosphate; BCR, B cell receptor; CT, C-terminal; DAG, diacylglycerol; dko, double knockout; GAP, GTPase-activating protein; GPCR, G-protein-coupled receptor; HSC, hematopoietic stem cell; IL, interleukin; IP3, inositol 1,4,5-trisphosphate; ITAM, immunoreceptor tyros

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Characterization of store-operated Ca2+ channels in pancreatic duct epithelia

Keywords: IP3، inositol 1،4،5-trisphosphate; IP3, inositol 1,4,5-trisphosphate; ATP, adenosine-5′-triphosphate; UTP, uridine-5′-triphosphate; SOCs, store-operated Ca2+ channels; PDEC, pancreatic duct epithelial cellsStore-operated Ca2+ channels; STIM; Orai; TRP; Epithelia; D1-ER cameleon; Ca2+ imagi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Actein induces calcium release in human breast cancer cells

Keywords: IP3، inositol 1،4،5-trisphosphate; DAG, diacylglycerol; D7, diospyrin diethylether; ER, endoplasmic reticulum; IP3, inositol 1,4,5-trisphosphate; Lipo-actein, liposome-actein; PIP2, phosphatidylinositol-4,5-bisphosphate; PLC, phospholipase C; TNFα, transforming growth factor alpha.Inflamma

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Profiling of the Bcl-2/Bcl-XL-binding sites on type 1 IP3 receptor

Keywords: IP3، inositol 1،4،5-trisphosphate; aa, amino acids; Bcl-2, B-cell lymphoma 2; Bcl-XL, B-cell lymphoma extra large; ER, endoplasmic reticulum; GST, glutathione S-transferase; IP3, inositol 1,4,5-trisphosphate; IP3R, IP3 receptor; Mcl-1, myeloid cell leukemia sequence 1; MAM, mitochondria-as

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Intracellular signaling and membrane trafficking control bidirectional growth cone guidance

Keywords: IP3، inositol 1،4،5-trisphosphate; BDNF, brain-derived neurotrophic factor; cAMP, cyclic AMP; cGMP, cyclic GMP; CICR, Ca2+-induced Ca2+ release; CNGC, cyclic nucleotide-gated ion channel; IP3, inositol 1,4,5-trisphosphate; IICR, IP3-induced Ca2+ release; IP3R, IP3 receptor; MAG, myelin-ass

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The regulation and packaging of synaptic vesicles as related to recruitment within glutamatergic synapses

Keywords: IP3، inositol 1،4،5-trisphosphate; 5-HT, serotonin; CaM-K, CaM-kinase; CICR, Ca2+-induced Ca2+-release; EPSPs, excitatory postsynaptic potentials; GluT, glutamate transporter; Hepes, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; IP3, inositol 1,4,5-trisphosphate; IRP, immediately rel

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Genetic ablation and chemical inhibition of IP3R1 reduce mutant huntingtin aggregation

Keywords: IP3، inositol 1،4،5-trisphosphate; HD, Huntington’s disease; polyQ, polyglutamine; htt, huntingtin; IP3, inositol 1,4,5-trisphosphate; IP3R1, IP3 receptor type 1; 2-APB, 2-aminoethyl diphenylborinate; ER, endoplasmic reticulum; MSN, medium spiny neurons; Neuro2a cells, mouse neuroblastoma

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Syk mediates BCR- and CD40-signaling integration during B cell activation

Keywords: IP3، inositol 1،4،5-trisphosphate; Ab, antibody; Ag, antigen; BLNK, B cell linker; BM, bone marrow; Btk, Bruton tyrosine kinase; ERK, extracellular signal regulated kinase; IP3, inositol 1,4,5-trisphosphate; JNK, c-Jun NH2-terminal kinase; PKC, protein kinase C; MAPK, mitogen-activated pro

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Calcium signalling in T-lymphocytes

Keywords: IP3، inositol 1،4،5-trisphosphate; Calcium; Lymphocytes; IP-3 receptors; Ryanodine receptors; ORAI channels; Cav channelsCRAC channels, Calcium release activated Ca2+; cADPR, Cyclic adenosine diphosphate ribose; IP3, Inositol 1,4,5-trisphosphate; IL, Interleukin; [Ca]i, Intracellular calci

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Phospholipidic signaling and vanillin production in response to salicylic acid and methyl jasmonate in Capsicum chinense J. cells

Keywords: IP3، inositol 1،4،5-trisphosphate; Phospholipids; Methyl jasmonate; Salicylic acid; Phospholipase C; Phospholipase D; Lipid kinases; VanillinABA, abscisic acid; BSA, bovine serum albumin; DAG, diacylglycerol; DGK, diacylglycerol kinase; IP3, inositol 1,4,5-trisphosphate; MJ, methyl jasmona

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Thapsigargin activates Ca2+ entry both by store-dependent, STIM1/Orai1-mediated, and store-independent, TRPC3/PLC/PKC-mediated pathways in human endothelial cells

Keywords: IP3، inositol 1،4،5-trisphosphate; SOCE, store-operated Ca2+ entry; IP3, inositol 1,4,5-trisphosphate; ER, endoplasmatic reticulum; SERCA, sarco-endoplasmic reticulum Ca2+ ATPase; TG, thapsigargin; PKC, protein kinase C; DAG, diacylglycerol; PLC, phospholipase C; TRPC, canonical transient

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Phospholipase C-γ1 is required for the epidermal growth factor receptor-induced squamous cell carcinoma cell mitogenesis

Keywords: IP3، inositol 1،4،5-trisphosphate; SCC, squamous cell carcinoma; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; PLC, phospholipase C; PLC-β1, phospholipase C-β1; PLC-γ1, phospholipase C-γ1; PLC-δ1, phospholipase C-δ1; IP3, inositol 1,4,5-trisphosphate; DAG, diacylgly

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Calcium fluxes cause nuclear shrinkage and the translocation of phospholipase C-δ1 into the nucleus

Keywords: IP3، inositol 1،4،5-trisphosphate; MEF, murine embryonic fibroblast; NLS, nuclear localization signal; PIP2, phosphatidylinositol 4,5-bisphosphate; IP3, inositol 1,4,5-trisphosphate; DIV, days in vitro; PLC, phospholipase CGlutamate neurotoxicity; Phospholipase C-δ1; Nuclear localization;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Homer regulation of native plasma membrane calcium channels in A431 cells

Keywords: IP3، inositol 1،4،5-trisphosphate; PLC, phospholipase C; Ca2+, calcium; IP3, inositol 1,4,5-trisphosphate; SOC, store-operated calcium channels; EVH1, Homer N-terminal enabled/vasodilator-stimulated phosphoprotein homology domain; CC, Homer C-terminal coil-coiled domain; IP3R, the inositol

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

ORAI-mediated calcium entry: Mechanism and roles, diseases and pharmacology

Keywords: IP3، inositol 1،4،5-trisphosphate; BTP2, N-[4-3, 5-bis(trifluromethyl)pyrazol-1-yl]-4-methyl-1,2,3-thiadiazole-5-carboxamide; Ca2+, free calcium; CPA, cyclopiazonic acid; CYP, cytochrome P450; ER, endoplasmic reticulum; Gd3+, gadolinium; IP3, inositol 1,4,5-trisphosphate; NFAT, nuclear fac

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Specific disruption of astrocytic Ca2+ signaling pathway in vivo by adeno-associated viral transduction

Keywords: IP3، inositol 1،4،5-trisphosphate; adeno-associated virus; glial promoter; Ca2+ signaling; two-photon imagingACSF, artificial cerebral spinal fluid; CMV, cytomegalovirus; GFAP, glial fibrillary acidic protein; GPCRs, G-protein coupled receptors; IP3, inositol 1,4,5-trisphosphate; NeuN, Neu

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Hydrogen peroxide down-regulates inositol 1,4,5-trisphosphate receptor content through proteasome activation

Keywords: IP3، inositol 1،4،5-trisphosphate; ANGII, angiotensin II; AT1R1, angiotensin II receptor 1; IP3, inositol 1,4,5-trisphosphate; IP3R, inositol 1,4,5-trisphosphate receptor; MLCK, myosin light chain kinase; CAT, catalase; ALLN, N-acetyl-leucyl-leucyl-norleucinal; VSMC, vascular smooth muscle

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Nav1.7 sodium channel-induced Ca2+ influx decreases tau phosphorylation via glycogen synthase kinase-3β in adrenal chromaffin cells

Keywords: IP3، inositol 1،4،5-trisphosphate; cPKC-α, conventional protein kinase C-α; DAG, diacylglycerol; DMSO, dimethyl sulfoxide; GSK-3, glycogen synthase kinase-3; IP3, inositol 1,4,5-trisphosphate; PI3K, phosphatidylinositol 3-kinase; PIP2, phosphatidylinositol 4,5-bisphosphate; PIP3, phosphati

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

The Bv8 gene from Bombina orientalis: Molecular cloning, genomic organization and functional characterization of the promoter

Keywords: IP3، inositol 1،4،5-trisphosphate; PCR, polymerase chain reaction; PK1 and PK2, prokineticin 1 and 2; EG-VEGF, endocrine gland-derived vascular endothelial growth factor; EMSA, electrophoretic mobility shift assay; CsA, cyclosporin A; IP3, inositol 1,4,5-trisphosphate; DAG, diacylglycerolB

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK

Keywords: IP3، inositol 1،4،5-trisphosphate; LPA, lysophosphatidic acid; GPCR, G protein-coupled receptor; GRK, G protein-coupled receptor kinase; HEK, human embryonic kidney; PTX, 293 cells, pertussis toxin; MEFs, mouse embryonic fibroblasts; IP3, inositol 1,4,5-trisphosphate; ARF, ADPribosylation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Diverse deafness mechanisms of connexin mutations revealed by studies using in vitro approaches and mouse models

Keywords: IP3، inositol 1،4،5-trisphosphate; 2-NBDG, 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-d-glucose; Cx, connexin; eGFP, enhanced green fluorescent protein; EP, endolymphatic potential; GJ, gap junction; IP3, inositol 1,4,5-trisphosphate; Panxs, pannexins; ROS, reactive oxygen spec

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2009 سفارش ترجمه

Evidence for a receptor-activated Ca2+ entry pathway independent from Ca2+ store depletion in endothelial cells

Keywords: IP3، inositol 1،4،5-trisphosphate; CCE, capacitative Ca2+ entry; SOCE, store-operated Ca2+ entry; RACE, receptor-activated Ca2+ entry; IP3, inositol 1,4,5-trisphosphate; ER, endoplasmatic reticulum; SERCA, sarco-endoplasmic reticulum Ca2+ ATPase; TG, thapsigargin; D1ER, ER targeted cameleo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Multi-photon microscopic imaging of rat parotid ducts demonstrates cellular heterogeneity in Ca2+ responsiveness

Keywords: IP3، inositol 1،4،5-trisphosphate; Epi, epinephrine; [Ca2+]i, intracellular Ca2+; PhL, phenylephrine; CCh, carbachol; IP3, inositol 1,4,5-trisphosphate; BSA, bovine serum albumin; fura-2/AM, fura-2 acetoxymethyl ester; HBSS-H, Hanks’ balanced salt solution buffered with 20 mM HEPES; IP3Rs,

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line

Keywords: IP3، inositol 1،4،5-trisphosphate; BGS, bovine growth serum; Ca2+, calcium; Fluo-3-AM, fluo-3-acetoxymethyl ester; IP3, inositol 1,4,5-trisphosphate; IP3-AM, inositol 1,4,5-trisphoshpate acetoxymethyl ester; IP3R, inositol 1,4,5-trisphosphate receptor; Tmax1/2Tmax1/2, time to half-maximal;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Neurotensin receptor mechanisms and its modulation of glutamate transmission in the brain: Relevance for neurodegenerative diseases and their treatment

Keywords: IP3، inositol 1،4،5-trisphosphate; CalC, calphostin C; CNS, central nervous system; DA, dopamine; ERK, extracellular signal-regulated kinase; IP3, inositol 1,4,5-trisphosphate; MAPK, mitogen-activated protein kinases; NMDA, N-methyl-d-aspartate; NT, neurotensin; PD, Parkinson's disease; PI

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2007 سفارش ترجمه

Signal transduction pathways leading to Ca2+ release in a vertebrate model system: Lessons from Xenopus eggs

Keywords: IP3، inositol 1،4،5-trisphosphate; [Ca2+]i, intracellular-free Ca2+ concentration; IP3, inositol 1,4,5-trisphosphate; IP4, inositol 1,3,4,5-tetrakisphosphate; PLC, phospholipase; PI, phosphatidylinositol; PIP2, phosphatidylinositol 4,5-bisphosphate; DG, diacylglycerol; PKC, protein kinase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Differential coupling of the P2Y1 receptor to Gα14 and Gαq/11 proteins during the development of the rat salivary gland

Keywords: IP3، inositol 1،4،5-trisphosphate; [Ca2+]i, intracellular Ca2+ concentration; ERK, extracellular signal regulated kinase; G3PDH, glyceraldehyde-3-phosphate dehydrogenase; IP3, inositol 1,4,5-trisphosphate; MAPK, mitogen-activated protein kinase; 2-MeSADP, 2-methylthio-ADP; 2-MeSATP, 2-meth

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels

Keywords: IP3، inositol 1،4،5-trisphosphate; AD, Alzheimer's disease; FAD, familial form of Alzheimer's disease; Aβ, amyloid β-peptide; APP, amyloid precursor protein; PS, presenilin; ER, endoplasmic reticulum; IP3, inositol 1,4,5-trisphosphate; Bk, bradykinin; Hist, histamine; Cch, carbachol; Tg, t

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Ca2+ microdomains and the control of insulin secretion

Keywords: IP3، inositol 1،4،5-trisphosphate; Ca2+ microdomains; Exocytosis; Protein kinases; Mitochondria; Insulin; β-Cell[Ca2+]c, [Ca2+]m and [Ca2+]pm, cytosolic, mitochondrial and sub-plasma membrane free Ca2+ concentrations, respectively; IP3, inositol 1,4,5-trisphosphate; KATP, ATP-sensitive pot

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه