Keywords: Tufting entéropathies; CACP; IPEX; APECED; Achalasie; Entéropathie exsudative; Panniculite mésentérique; PPP; Pancréas; Cholangites; Hépatites auto-immunes; Tufting enteropathy; CACP; IPEX; APECED; Achalasia; Exsudative enteropathy; Mésenteric pann
مقالات ISI (ترجمه نشده)
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Keywords: Flow cytometry; Intracellular protein; Monoclonal antibody; Primary immunodeficiency disease; Surface protein; ADA; adenosine deaminase; ALPS; autoimmune lymphoproliferative syndrome; APECED; autoimmune polyendocrinopathy-candidiasis-ectodermal dystrop
Keywords: Ginger; Multiple sclerosis; Experimental autoimmune encephalomyelitis; Therapeutic potentials; AP-1; Activator protein 1; APCs; Antigen-presenting cells; ASC; apoptosis speck-like protein containing CARD; BAFF; B cell-activating factor belonging to the TN
Keywords: Hematopoietic stem cell transplantation; gammaretroviral vector; lentiviral vector; gene editing; site-specific endonuclease; zinc finger nuclease; CRISPR/Cas9; ADA-SCID; Adenosine deaminase-deficient severe combined immunodeficiency; CGD; Chronic granu
Keywords: Primary immunodeficiencies; Common variable immunodeficiency; Autoimmunity; Granulomatous and lymphocytic interstitial lung disease; IPEX; Immune dysregulation, polyendocrinopathy, enteropathy, X-linked;
Keywords: Very early onset IBD (VEO-IBD); IPEX; IL-10 defects; Inflammasome; Epithelial barrier defects; Neutrophil defects; T cell or B cell defects;
Keywords: Inflammatory Bowel Diseases; Hematopoietic Stem Cell Transplantation; Mesenchymal Stem Cell Transplantation; AD; adipocyte-derived; BM; bone marrow; CD; Crohn's disease; CDAI; Crohn's Disease Activity Index; HSCT; hematopoietic stem cell transplantati
Keywords: AD; autosomal dominant; AD-HIES; autosomal dominant hyper-immunoglobulin E syndrome; AR; autosomal recessive; BMD; bone mineral density; CMC; chronic mucocutaneous candidiasis; DOCK8; dedicator of cytokinesis 8; EBV; Epstein-Barr virus; FOXP3; forkhea
Keywords: AAG; autoimmune atrophic gastritis; AEA; anti-enterocyte antibody; AIE; autoimmune enteropathy; APECED; autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy; ATP-ase; adenosine triphosphatase; CD; celiac disease; ECL; enterochromaffin-like;
Fine tuning subsets of CD4+ T cells by low-dosage of IL-2 and a new therapeutic strategy for autoimmune diseases
Keywords: aa; Amino acids; A region; Acidic region of IL-2Rβ; AKT; Protein kinase B; AA; Alopecia Areata; CTLA-4; Cytotoxic T lymphocyte antigen-4; cDNA; Complementary DNA; Foxp3; Forkhead box P3; GVHD; Chronic graft-versus-host disease; HCV; Hepatitis C virus; hd
T-regulatory cells-Triumph of perseverance: The Crafoord Prize for Polyarthritis in 2017
Keywords: Regulatory T cells; Scurfy; IPEX; FoxP3; CTLA-4; Low dose IL-2; Autoimmunity;
Molecular adjuvants that modulate regulatory T cell function in vaccination: A critical appraisal
Keywords: ADCC; antibody dependent cell cytotoxicity; CD; cluster of differentiation; mAb; monoclonal antibody; CsA; cyclosporine; CTLA-4; T-lymphocyte antigen 4; GITR; glucocorticoid-induced tumor necrosis factor receptor (TNFR) family related gene; CCR4; C-C chem
IPEX due to an exon 7 skipping FOXP3 mutation with autoimmune diabetes mellitus cured by selective TReg cell engraftment
Keywords: IPEX; FOXP3; Splice site mutation; TReg; HSCT; Autoimmune diabetes mellitus;
TNFAIP3 haploinsufficiency is the cause of autoinflammatory manifestations in a patient with a deletion of 13Mb on chromosome 6
Keywords: Autoinflammatory diseases; Behçet's disease; TNFAIP3; Comparative Genomic Hybridization (CGH); Chromosome deletion; Oral ulcer; ESID; European Society for Immunodeficiencies; ENT; Ear-nose-throat; NF-kB; Nuclear factor kappa-light-chain-enhancer of act
Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study
Keywords: IPEX; primary immune deficiency; FOXP3; Treg cells; hematopoietic stem cell transplantation; immunosuppression; rapamycin; enteropathy; neonatal diabetes; genetic autoimmunity; DFS; Disease-free survival; FKH; Forkhead domain; GvHD; Graft-versus-host dise
Implications of uterine NK cells and regulatory T cells in the endometrium of infertile women
Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; ART; assisted reproductive technology; dNK cells; decidual natural killer cells; CTLA-4; cytotoxic T-lymphocyte antigen-4; EVT; extra-villous trophoblast; G-CSF; granulocyte colony-stimulating factor; G
Curcumin attenuates the scurfy-induced immune disorder, a model of IPEX syndrome, with inhibiting Th1/Th2/Th17 responses in mice
Keywords: Curcumin; Tumeric; IPEX; Scurfy; T cell; HSCT; Hematopoietic stem cell transplantation; IPEX syndrome; Immunodysregulation polyendocrinopathy enteropathy X-linked syndrome; Treg; Regulatory T cell;
Review articleDirect control of B cells by Tregs: An opportunity for long-term modulation of the humoral response
Keywords: Tregs; regulatory T cells; IPEX; Immunodysregulation Polyendocrinopathy Enteropathy X-linked syndrome; Th; T helper cells; APCs; Antigen Presenting Cells; TFR; T follicular regulatory cells; TFH; T follicular helper cells; SLE; Systemic Lupus Erythematosu
DOCK8 deficiency: Insights into pathophysiology, clinical features and management
Keywords: Actin; CDC42; Combined immunodeficiency; Dedicator of cytokinesis; DOCK2; DOCK8; Hyper IgE syndrome; Primary immunodeficiency; RAC1; STAT3; AR-HIES; autosomal recessive hyper IgE syndrome; AD-HIES; autosomal dominant hyper IgE syndrome; CDC42; cell divisi
Clinical and structural impact of mutations affecting the residue Phe367 of FOXP3 in patients with IPEX syndrome
Keywords: FOXP3; IPEX; Primary immunodeficiency; Autoimmunity; Mutation;
The extended phenotype of LPS-responsive beige-like anchor protein (LRBA) deficiency
Keywords: LPS-responsive beige-like anchor protein; primary immunodeficiency; common variable Immunodeficiency; autoimmunity; hypogammaglobulinemia; enteropathy; lymphoproliferation; ALPS; Autoimmune lymphoproliferative syndrome; ALPS-Ph; Autoimmune lymphoprolifera
Analysis of FOXP3 gene in children with allergy and autoimmune diseases
Keywords: Allergy; Asthma; Atopy; Autoimmunity; FOXP3; Gene; IPEX; Polymorphisms; Paediatrics; Treg
Dissecting the role of the foxp3 gene in the joint genetic susceptibility to autoimmune thyroiditis and diabetes: A genetic and functional analysis
Keywords: APS3v; autoimmune polyglandular syndrome type 3; AIRE; autoimmune regulator; AITD; autoimmune thyroiditis; bp; base pair(s); CTLA-4; cytotoxic T-lymphocyte antigen; Î; deletion; dNTP; deoxyribonucleoside triphosphate; FOXP3; Forkhead Box Protein 3; GAPDH
Immunogenetics of autoimmune thyroid diseases: A comprehensive review
Keywords: Autoimmune thyroid disease; Graves' disease; Hashimoto's thyroiditis; Autoimmunity; Immunogenetics; Polymorphism; TSHR; thyrotropin receptor; FOXP3; forkhead box P3; CTLA-4; cytotoxic T-lymphocyte-associated molecule-4; PTPN22M; protein tyrosine phosphata
Cholecalciferol supplementation improves suppressive capacity of regulatory T-cells in young patients with new-onset type 1 diabetes mellitus - A randomized clinical trial
Keywords: BW; body weight; IPEX; immunodysregulation, polyendocrinopathy, enteropathy, X-linked syndrome; T1D; diabetes mellitus type 1; Teffs; effector T cells; Tregs; regulatory T cells; VDR; vitamin D receptor; Type 1 diabetes; Regulatory T cells; Suppressive ca
Foxp3 lacking exons 2 and 7 is unable to confer suppressive ability to regulatory T cells in vivo
Keywords: FOXP3; Isoforms; Inflammatory disease; B cell lymphopoiesis; Scurfy; IPEX;
Gastrointestinal immunity against tryptophan hydroxylase-1, aromatic L-amino-acid decarboxylase, AIE-75, villin and Paneth cells in APECED
Keywords: AADC; aromatic L-amino acid decarboxylase; AIE-75; autoimmune enteropathy (AIE)-related 75Â kDa antigen; AIRE; autoimmune regulator gene; APECED; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy; hD5; human defensin 5; CgA; chromogranin A; E
Anti-CD4 treatment inhibits autoimmunity in scurfy mice through the attenuation of co-stimulatory signals
Keywords: Scurfy; Anti-CD4; Foxp3; Autoimmunity; YTS177.9; IPEX;
Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance
Keywords: SLAM-associated protein; signaling lymphocytic activation molecule; B-cell tolerance; regulatory T cells; ANA; Anti-nuclear antibody; APC; Allophycocyanin; BAFF; B cell-activating factor of the TNF family; BCR; B-cell receptor; CFSE; Carboxyfluorescein
Diagnosis and Treatment of Gastrointestinal Disorders in Patients With Primary Immunodeficiency
Keywords: Immune System; Hypogammaglobulinemia; IBD; Inflammatory Intestinal Disease; 6-MP; mercaptopurine; AZA; azathioprine; CGD; chronic granulomatous disease; CVID; common variable immunodeficiency; FOXP3; forkhead box P3; GI; gastrointestinal; GVHD; graft-vers
The X chromosome and immune associated genes
Keywords: Sex chromosomes; Genetic factors; Autoimmunity; Female preponderance; Etiopathogenesis; AID; autoimmune diseases; GWAS; genome-wide association study; PBC; primary biliary cirrhosis; MHC; major histocompatibility complex; PID; primary immunodeficiency syn
Cutting edge assessment of the impact of autoimmunity on female reproductive success
Keywords: FMR1 (fragile X) gene; Autoimmunity; Ovarian reserve; Female infertility; BM15; bone morphogenic protein-15 gene; FMR1; fragile X mental retardation 1; FoxP3; Forkhead Box p3; het; heterozygous; HIGM; immunodeficiency with hyper-IgM; HLA; histocompatibili
Autoantibodies to villin occur frequently in IPEX, a severe immune dysregulation, syndrome caused by mutation of FOXP3
Keywords: IPEX; immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome; AIE-75; autoimmune enteropathy-related 75Â kDa antigen; FOXP3; forkhead box protein 3; GST; glutathione-S-transferase; DAB; 3,3â²-diaminobenzidine; PCR; polymerase chain reac
Advances in mechanisms of asthma, allergy, and immunology in 2010
Keywords: Allergic conjunctivitis; allergic inflammation; anaphylaxis; asthma; asthma genetics; atopic dermatitis; cytokines; eosinophils; food allergy; immediate hypersensitivity; mast cells; nasal polyposis; polymorphisms; CSS; Churg-Strauss syndrome; cysLT; Cyst
Domain requirements for the diverse immune regulatory functions of foxp3
Keywords: Th; T helper; MFI; mean fluorescence intensity; IPEX; immune dysfunction polyendocrinopathy enteropathy X-linked syndrome; IBD; inflammatory bowel diseases; Foxp3; Treg cells; Mutagenesis; Autoimmunity; Th1/Th2 cells;
IMMUNE REGULATIONIdentification of FOXP3-negative regulatory T-like (CD4+CD25+CD127low) cells in patients with immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome
Keywords: APC; antigen-presenting cells; FKH; forkhead; FOXP3; forkhead box protein 3; HSCT; hematopoietic stem cell transplantation; mAb; monoclonal antibodies; MLR; mixed lymphocyte reaction; IPEX; immune dysregulation, polyendocrinopathy, enteropathy, X-linked;
Moving to tolerance: Clinical application of T regulatory cells
Keywords: APC; antigen presenting cell; ATG; anti thymocyte globulin; aTreg; adaptive T regulatory cell; AZT; 3â²-azido-3â²-deoxythymidine; CNI; calcineurin inhibitor; CyA; cyclosporin A; DC; dendiric cell; DST; donor specific transfusion; GVHD; graft versus host
Point mutants of forkhead box P3 that cause immune dysregulation, polyendocrinopathy, enteropathy, X-linked have diverse abilities to reprogram T cells into regulatory T cells
Keywords: T regulatory cells; IPEX; FOXP3; autoimmunity; tolerance; IL-17; APC; Antigen-presenting cell; ÎNGFR; Truncated nerve growth factor receptor; FOXP3; Forkhead box P3; [3H]-TdR; Tritiated thymidine; IPEX; Immune dysregulation, polyendocrinopathy, enteropat
FOXP3: Controlador maestro de la generación y función de las células reguladoras naturales
Keywords: FOXP3; IPEX; Tregs; Células T reguladoras; FOXP3; IPEX; Regulatory T cells; Tregs;
Advances in basic and clinical immunology in 2008
Keywords: Basic immunology; antigen presentation; regulatory T cells; clinical immunology; primary immunodeficiency; hereditary angioedema; hematopoietic stem cell transplantation; partial DiGeorge syndrome; HIV infection; ACE; Angiotensin-converting enzyme; ADA; A
Regulatory T Cells: Key Players in Tolerance and Autoimmunity
Keywords: Regulatory T cells; Foxp3; Tolerance; Autoimmunity; IPEX; CD25
Diagnosis and Management of Polyendocrinopathy Syndromes
Keywords: APS2; APS1; IPEX
Cellules T régulatrices et lupus érythémateux systémique
Keywords: Treg; Cellule T régulatrice; iTreg; Cellule T régulatrice induite ou adaptative; AICD; Activation-induced cell death; IPEX; Immune dysregulation polyendocrinopathy X-linked syndrome; FoxP3; Forkhead/winged-helix protein 3; Cellules T régulatrices; Lupu
Primary immune deficiencies with aberrant IgE production
Keywords: IgE; primary immune deficiency; HIES; WAS; IPEX; Omenn syndromeADA, Adenosine deaminase; AD-HIES, Autosomal-dominant hyper-IgE syndrome; AID, Activation-induced cytidine deaminase; APRIL, A proliferation-inducing ligand; AR-HIES, Autosomal-recessive hyper
De l’Ipex à foxp3 : une nouvelle contribution de la pédiatrie à la compréhension du système immunitaire
Keywords: Ipex; Entéropathie auto-immune; Polyendocrinopathie; Diarrhée néonatale; Treg
CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked–like syndrome, and defective IL-10 expression from CD4 lymphocytes
Keywords: IPEX; IL-10; IL-2; CD25; Foxp3CMV, Cytomegalovirus; Foxp3, Forkhead box P3; IL-2R, IL-2 receptor; IPEX, immune dysregulation, polyendocrinopathy, enteropathy, X-linked; TR, T-regulatory
Developmental changes of FOXP3-expressing CD4+CD25+ regulatory T cells and their impairment in patients with FOXP3 gene mutations
Keywords: FOXP3; Regulatory T cells; Developmental change; Naive T cells; Memory T cells; IPEX
Clinical-alimentary tractSevere FOXP3+ and Naïve T Lymphopenia in a Non-IPEX Form of Autoimmune Enteropathy Combined With an Immunodeficiency
Keywords: AIE; autoimmune enteropathy; CTLA-4; cytotoxic T lymphocyte-associated antigen-4; GITR; glucocorticoid-induced TNF-related receptor; IPEX; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; PBMC; peripheral blood mononuclear cells; PE; phyco
Severe Food Allergy as a Variant of IPEX Syndrome Caused by a Deletion in a Noncoding Region of the FOXP3 Gene
Keywords: IPEX; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; PBMC; peripheral blood mononuclear cells; PHA; phytohemagglutinin; TREG; regulatory T lymphocytes;