دانلود مقالات ISI درباره IRE1a + ترجمه فارسی

Tyrosol, an olive oil polyphenol, inhibits ER stress-induced apoptosis in pancreatic β-cell through JNK signaling

Keywords: IRE1a; Tyrosol; ER stress; β-Cell failure; Apoptosis; NIT-1; ER; endoplasmic reticulum; UPR; unfolded protein response; PERK; protein kinase-like endoplasmic reticulum kinase; ATF6; activating transcription factor 6; IRE1α; inositol-requiring kinase 1α; HFD;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

4-Phenylbutyric acid reduces mutant-TGFBIp levels and ER stress through activation of ERAD pathway in corneal fibroblasts of granular corneal dystrophy type 2

Keywords: IRE1a; ER stress; UPR; ERAD; 4-Phenylbutyric acid; TGFBIp; GCD2; Corneal fibroblasts; 4-PBA; Sodium 4-phenylbutyric acid; ATF6; Activating transcription factor 6; BiP; Binding immunoglobulin protein; CHOP; C/EBP homologous protein; ER; Endoplasmic reticulum; ERA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Activation of IRE1α-XBP1 pathway induces cell proliferation and invasion in colorectal carcinoma

Keywords: IRE1a; ER stress; IRE1α; Colorectal carcinoma; Cell proliferation; Epithelial-to-mesenchymal transition;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Anti-inflammatory actions of (−)-epicatechin in the adipose tissue of obese mice

Keywords: IRE1a; ATF6; activating transcription factor 6; EC; (−)-epicatechin; ER; endoplasmic reticulum; Ero1; FAD-dependent enzyme ER oxireductin-1 (Ero1); HFD; high fat diet; 4-HNE; 4-hydroxynonenal; IκB; inhibitor of nuclear factor κB; IKK; IκB kinase; IL-6; inte

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleHeat stress promotes the down-regulation of IRE1α in cells: An atypical modulation of the UPR pathway

Keywords: IRE1a; ATF6; activating transcription factor-6; CHX; cycloheximide; eIF2α; phospho-eukaryotic initiation factor 2α; ER; endoplasmic reticulum; ERAD; ER-associated degradation; IRE1α; inositol-requiring protein-1α; MEF; mouse embryonic fibroblast; PDI; protei

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Astemizole-Histamine induces Beclin-1-independent autophagy by targeting p53-dependent crosstalk between autophagy and apoptosis

Keywords: IRE1a; AST; Astemizole; HIS; Histamine; H1R; Histamine H1 receptor; ROS; Reactive oxygen species; ER; Endoplasmic reticulum; PERK; Protein kinase R-like endoplasmic reticulum kinase; IRE1α; Inositol-requiring enzyme 1; ATF; Activating transcription factor; JNK;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Quercetin attenuates tau hyperphosphorylation and improves cognitive disorder via suppression of ER stress in a manner dependent on AMPK pathway

Keywords: IRE1a; AMPK; ER stress; NLRP3 inflammasome; Quercetin; Quercetin-3-O-glucuronide; Tau phosphorylation; Compound C (PubChem CID: 11524144); Metformin (PubChem CID: 14219); Okadaic acid (PubChem CID: 446512); Quercetin (PubChem CID: 5280343); Quercetin-3-O-glucuro

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress

Keywords: IRE1a; AcvR2B; activin receptor IIB; sAcvR2B-Fc; ligand blocking using soluble activin receptor-Fc; AMPK; 5′ adenosine monophosphate-activated protein kinase; CSA; cross-sectional area; DMD; Duchenne muscular dystrophy; mdx; DMD mouse model; eIF2α; eukaryotic

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal

Keywords: IRE1a; Ovarian cancer; DBeQ; ML240; Salubrinal; ER stress; Unfolded protein response; CB-5083; Synergy; AAA-ATPase; ATPase associated with diverse cellular activities; BRCA1/2; breast cancer 1/2; PARP1; poly ADP-ribose polymerase-1; DBeQ; N2,N4-dibenzylquinazoli

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBPα Homologous Protein activation attenuates leptin and Insulin-like growth factor 1 expression in the brain

Keywords: IRE1a; 4-PBA; 4-phenyl butyric acid; 6-OHDA; 6-hydroxydopamine; Aβ; amyloid beta; AD; Alzheimer's disease; ATF3; activating transcription factor 3; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; BACE1; β-site APP cleaving enz

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Role of miR-181a-5p and endoplasmic reticulum stress in the regulation of myogenic differentiation

Keywords: IRE1a; ATF6; activating transcription factor 6; BMP4; bone morphogenetic protein 4; DM; differentiation medium; ER; endoplasmic reticulum; GM; growth medium; GRP78/BIP; glucose-regulated protein of 78 kDa/binding protein for immunoglobulins; IGF-1; insulin-like

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

Suppression of StarD7 promotes endoplasmic reticulum stress and induces ROS production

Keywords: IRE1a; BSA; bovine serum albumin; CHX; cycloheximide; DMSO; dimethyl sulfoxide; ER; endoplasmic reticulum; eIF2α; eukaryotic translation initiation factor 2, subunit 1α; GRP78/BiP; glucose regulated protein 78/immunoglobulin heavy chain-binding protein; H2DCFD

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response

Keywords: IRE1a; Netrin; UPR; Hepatocyte; Translation; ATF6; activated transcription factor 6; CMV; cytomegalovirus; DAPK; death-associated protein kinase; DMS; dimethyl sulfate; DR; dependence receptor; DTT; dithiothreitol; eIF2α; Eukaryotic translation initiation facto

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Alpha-lipoic acid attenuates endoplasmic reticulum stress-induced insulin resistance by improving mitochondrial function in HepG2 cells

Keywords: IRE1a; ALA; alpha-lipoic acid; ER stress; endoplasmic reticulum (ER) stress; HepG2; hepatoblastoma cell line; Tun; tunicamycin; OXPHOS; oxidative phosphorylation; Olig; oligomycin; T2DM; type 2 diabetes mellitus; IRS; insulin receptor substrate; PI3K; phosphatid

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Gu-Ben-Fang-Xiao decoction attenuates sustained airway inflammation by suppressing ER stress response in a murine asthma remission model of respiratory syncytial virus infection

Keywords: IRE1a; GBFXD; GuBenFangXiao decoction; RSV; respiratory syncytial virus; OVA; ovalbumin; ER; endoplasmic reticulum; UPR; unfolded protein response; TCM; traditional Chinese medicine; Mont; montelukast sodium; DEX; dexamethasone; HPLC; high performance liquid chr

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Unfolded protein response induced by Brefeldin A increases collagen type I levels in hepatic stellate cells through an IRE1α, p38 MAPK and Smad-dependent pathway

Keywords: IRE1a; HSC; hepatic stellate cells; ER; endoplasmic reticulum; BFA; Brefeldin A; IRE1α; inositol-requiring enzyme 1 alpha; ATF6α; activating transcription factor 6α; PERK; PKR-like ER kinase; PBA; phenylbutyric acid; ERK; extracellular-regulated kinase; JNK;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleRole for the endoplasmic reticulum stress sensor IRE1α in liver regenerative responses

Keywords: IRE1a; IRE1α; inositol-requiring enzyme 1α; ER; endoplasmic reticulum; CCl4; carbon tetrachloride; PH; partial hepatectomy; UPR; unfolded protein response; LKO; liver specific IRE1α knockout; IL-6; interleukin 6; STAT3; signal transducer and activator of tran

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

SIRT1 suppresses cardiomyocyte apoptosis in diabetic cardiomyopathy: An insight into endoplasmic reticulum stress response mechanism

Keywords: IRE1a; AGEs; advanced glycation end products; CHOP; CCAAT/enhancer-binding protein homologous protein; DCM; diabetic cardiomyopathy; eIF2α; eukaryotic initiation factor 2α; IRE1α; inositol-requiring transmembrane kinase and endonuclease 1α; JNK; Jun-amino-te

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Taxol-induced unfolded protein response activation in breast cancer cells exposed to hypoxia: ATF4 activation regulates autophagy and inhibits apoptosis

Keywords: IRE1a; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; ER; endoplasmic reticulum; IRE1α; inositol-requiring enzyme-1α; PERK; protein kinase double-stranded RNA-dependent (PRK)-like ER kinase; UPR; unfolded protein response; Br

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Ilexgenin A inhibits endoplasmic reticulum stress and ameliorates endothelial dysfunction via suppression of TXNIP/NLRP3 inflammasome activation in an AMPK dependent manner

Keywords: IRE1a; ACC; acetyl-CoA carboxylase; ACh; acetylcholine; AICAR; AICA riboside; AMPK; AMP-activated protein kinase; ATF; activating transcription factor; ER; endoplasmic reticulum; FBS; fetal bovine serum; FFAs; free fatty acids; HFD; high-fat diet; IRE1α; inosit

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Dipeptidyl petidase-IV inhibitor (gemigliptin) inhibits tunicamycin-induced endoplasmic reticulum stress, apoptosis and inflammation in H9c2 cardiomyocytes

Keywords: IRE1a; ROS; reactive oxygen species; GLP-1; glucagon-like peptide-1; DPP-IV; dipeptidyl peptidase-IV; Erk; extracellular signal-regulated kinases; ER; endoplasmic reticulum; IL-6; interlukin-6; TNF-α; tumor necrosis factor-α; BNP; brain natriuretic peptide; SD

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Acrolein activates cell survival and apoptotic death responses involving the endoplasmic reticulum in A549 lung cells

Keywords: IRE1a; AFC; amino trifluorocoumarin; AKT; protein kinase B; AMC; amino methylcoumarin; ARE; antioxidant response element; ATF6; activating transcription factor-6; BAPTA-AM; 1,2-Bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid tetrakis (acetoxymethyl ester); Ba

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The neuroprotective effects of cordycepin inhibit glutamate-induced oxidative and ER stress-associated apoptosis in hippocampal HT22 cells

Keywords: IRE1a; Caffeine; adenosine A2A antagonist; CHOP; C/EBP homologous protein; DPCPX; 8-cyclopentyl-1,3-dipropylxanthine, adenosine A1 antagonist; Cor; cordycepin; ER; endoplasmic reticulum; Glu; glutamate; IRE1α; inositol-requiring enzyme 1α; MAPKs; mitogen-activ

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Modulation of endoplasmic reticulum (ER) stress-induced autophagy by C/EBP homologous protein (CHOP) and inositol-requiring enzyme 1α (IRE1α) in human colon cancer cells

Keywords: IRE1a; ER stress; Autophagy; IRE1α; CHOP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Selenite cataracts: Activation of endoplasmic reticulum stress and loss of Nrf2/Keap1-dependent stress protection

Keywords: IRE1a; AE1; anion exchanger 1; ATF6; activating transcription factor 6; BiP; immunoglobulin heavy-chain binding protein; CHOP; C/EBP-homologous protein; Dnmt; DNA methyltransferase; eIF2α; eukaryotic translation initiation factor 2α; ER; endoplasmic reticulum;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Oxidative stress induces mitochondrial dysfunction and a protective unfolded protein response in RPE cells

Keywords: IRE1a; AMD; age-related macular degeneration; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; CHOP; CCAAT/enhancer-binding protein-homologous protein; C/EBP-β; CCAAT/enhancer binding protein β; CSE; cigarette smoke extract; IR

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts

Keywords: IRE1a; H2-DCFH-DA; 2′,7′-dichlorodihydrofluorescein diacetate; 5-Aza; 5-aza-2′-deoxycytidine; 5-mC; 5-methylcytosine; ATF; activating transcription factor; AID; activation-induced deaminase; AGE; advanced glycation end-product; ARC; age-related cataract; A

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Positive contribution of IRE1α-XBP1 pathway to the expression of placental cathepsins

Keywords: IRE1a; IRE1α; XBP1; Cts7; Cts8;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

New small molecule inhibitors of UPR activation demonstrate that PERK, but not IRE1α signaling is essential for promoting adaptation and survival to hypoxia

Keywords: IRE1a; UPR; Hypoxia; Small-molecule inhibitors; PERK; IRE1α;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Differential inhibitory potencies and mechanisms of the type I ribosome inactivating protein marmorin on estrogen receptor (ER)-positive and ER-negative breast cancer cells

Keywords: IRE1a; CHOP; C/EBP homologous protein; E2; 17β-estradiol; ER; Estrogen receptor; ERα; Estrogen receptor α; ERβ; Estrogen receptor β; ERS; Endoplasmic reticulum stress; GRP75; A 75 kDa glucose regulated protein; IRE1α; Inositol-requiring protein 1 α; PERK;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development

Keywords: IRE1a; BiP; binding immunoglobulin protein; XBP1S; X-box binding protein1 spliced; UPR; unfolded protein response; BMP2; bone morphogenetic protein 2; IRE1α; inositol requiring enzyme 1α; PERK; PKR-like ER resistant kinase; ATF6; activating transcription facto

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

ER stress-induced cell death mechanisms

Keywords: IRE1a; AGE; advanced glycated end-products; ALS; amyotropic lateral sclerosis; AMD; age-related macular degeneration; ARE; antioxidant response elements; ASK1; apoptotic-signaling kinase-1; ATF4; activating transcription factor 4; ATF6; activating transcription

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2013 سفارش ترجمه

Oligomerization of the transmembrane domain of IRE1α in SDS micelles

Keywords: IRE1a; Endoplasmic reticulum; Transmembrane domain; Dimerization; IRE1α;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics

Keywords: IRE1a; ASK1; apoptosis signal-regulating kinase 1; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; BAX; Bcl2 associated X protein; BAK; BCL2-antagonist/killer; CHOP; C/EBP-homologous protein; eIF2α; eukaryotic initiation factor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibition of poly(ADP-ribose) polymerase inhibits ischemia/reperfusion induced neurodegeneration in retina via suppression of endoplasmic reticulum stress

Keywords: IRE1a; ATF6; activating transcription factor 6; Bip; immunoglobulin binding protein/glucose regulated protein; CHOP; CCAAT enhancer-binding protein homologous protein; eIF2α; eukaryotic translational initiation factor 2α; ER; endoplasmic reticulum; GCL; gangli

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Apelin alleviates diabetes-associated endoplasmic reticulum stress in the pancreas of Akita mice

Keywords: IRE1a; AMPKα; AMP-activated protein kinase; GRP78 (also known as Bip); glucose regulator protein 78; CHOP; C/EBP homologous protein; eIF2α; eukaryotic initiation factor 2α; ELISA; enzyme-linked immunosorbent assay; ER; endoplasmic reticulum; ERK1/2; extracell

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Carbon monoxide, a reaction product of heme oxygenase-1, suppresses the expression of C-reactive protein by endoplasmic reticulum stress through modulation of the unfolded protein response

Keywords: IRE1a; ATF6; activating transcription factor 6; CRP; C-reactive protein; CO; carbon monoxide; CORM-2; CO-releasing molecule-2 (tricarbonyl dichlororuthenium dimer); CORM-3; CO-releasing molecule-3 (tricarbonylchliro(glycinate)ruthenium); CREBH; cyclic AMP respon

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Death of photoreceptors in organotypic retinal explant cultures: Implication of rhodopsin accumulation and endoplasmic reticulum stress

Keywords: IRE1a; ATF6; activation transcription factor 6; CHOP; C/EBP homologous protein; eIF2α; eukaryotic initiator factor 2α; ER; endoplasmic reticulum; GRP78/BiP; glucose-regulated protein 78; IRE1α; inositol-requiring enzyme 1α; ONL; outer nuclear layer; PERK; pa

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Integrating stress signals at the endoplasmic reticulum: The BCL-2 protein family rheostat

Keywords: IRE1a; ER; endoplasmic reticulum; UPR; unfolded protein response; IRE1α; inositol-requiring transmembrane kinase/endonuclease; PERK; PKR-like ER kinase; ATF6; activating transcription factor 6; XBP-1; X-Box-binding protein 1; JNK; jun N-terminal kinase; ERK; ex

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

The HPV-16 E5 protein represses expression of stress pathway genes XBP-1 and COX-2 in genital keratinocytes

Keywords: IRE1a; Human papillomavirus type 16; E5 oncoprotein; COX-2; IRE1α; XBP-1; ER stress response; Unfolded protein response;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

X-box binding protein 1 regulates brain natriuretic peptide through a novel AP1/CRE-like element in cardiomyocytes

Keywords: IRE1a; BNP; brain natriuretic peptide; cDNA; complementary DNA; ER; endoplasmic reticulum; ERSE-I, -II; ER stress response elements I, II; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GRP78; glucose-regulated protein of 78 kDa; IRE1α; inositol requiring ki

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Intracellular Ca2+ storage in health and disease: A dynamic equilibrium

Keywords: IRE1a; Aβ; amyloid-β; AD; Alzheimer's disease; ADPKD; autosomal dominant polycystic kidney disease; APP; amyloid precursor protein; Bax; Bcl-2-associated Xprotein; BI-1; Bax Inhibitor-1; [Ca2+]cyt; cytosolic Ca2+ concentration; [Ca2+]ER; endoplasmic-reticulum

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2010 سفارش ترجمه