Simvastatin inhibits glucose uptake activity and GLUT4 translocation through suppression of the IR/IRS-1/Akt signaling in C2C12 myotubes
Keywords: IRS، بستر گیرنده انسولین; Simvastatin; Glucose transporter 4; Myotubes; IR-dependent IRS-1/PI3K/Akt pathway; New-onset diabetes; Rac1ML, mevalonolactone; HMG-CoA, 3-hydroxy-3-methyl-glu-taryl-CoA; IR, insulin receptor; IRS, insulin receptor substrate; GLUT4, glucose transporter me