دانلود مقالات ISI درباره IRS، بستر گیرنده انسولین + ترجمه فارسی

Simvastatin inhibits glucose uptake activity and GLUT4 translocation through suppression of the IR/IRS-1/Akt signaling in C2C12 myotubes

Keywords: IRS، بستر گیرنده انسولین; Simvastatin; Glucose transporter 4; Myotubes; IR-dependent IRS-1/PI3K/Akt pathway; New-onset diabetes; Rac1ML, mevalonolactone; HMG-CoA, 3-hydroxy-3-methyl-glu-taryl-CoA; IR, insulin receptor; IRS, insulin receptor substrate; GLUT4, glucose transporter me

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Stearoyl-CoA desaturase-1 and adaptive stress signaling

Keywords: IRS، بستر گیرنده انسولین; AMPK, AMP-activated protein kinase; ER, endoplasmic reticulum; IRS, insulin receptor substrate; MAPK, mitogen-activated protein kinase; mTOR, mechanistic target of rapamycin; MUFA, monounsaturated fatty acid; PERK, protein kinase RNA-like endoplasmic reti

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Zinc stimulates glucose consumption by modulating the insulin signaling pathway in L6 myotubes: essential roles of Akt–GLUT4, GSK3β and mTOR–S6K1

Keywords: IRS، بستر گیرنده انسولین; AMPK, AMP-activated protein kinase; DMEM, Dulbecco's modified Eagle's medium; FBS, fetal bovine serum; GLUT4, glucose transporter 4; IR, insulin receptor; GS, glycogen synthase; HS, horse serum; IRS, insulin receptor substrate; MAPK, mitogen-activated pro

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

IRE1 impairs insulin signaling transduction of fructose-fed mice via JNK independent of excess lipid

Keywords: IRS، بستر گیرنده انسولین; CH, chow; HFru, high fructose; DAG, diacylglycerol; PKCε, protein kinase C epsilon; IRS, insulin receptor substrate; UPR, unfolded protein response; IRE1, inositol-requiring protein 1; PERK, protein kinase RNA-like ER kinase; ATF6, activating transcriptio

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Hepatic proteomic analysis revealed altered metabolic pathways in insulin resistant Akt1+/−/Akt2−/− mice

Keywords: IRS، بستر گیرنده انسولین; IRS, insulin receptor substrate; PI3K, phosphoinositide 3-kinase; 2-D DIGE, two-dimensional differential gel electrophoresis; pI, isoelectric point; MALDI, matrix-assisted laser desorption/ionization; TOF, time of flightMouse; Liver; AKT; Insulin resistan

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Oleanolic acid supplement attenuates liquid fructose-induced adipose tissue insulin resistance through the insulin receptor substrate-1/phosphatidylinositol 3-kinase/Akt signaling pathway in rats

Keywords: IRS، بستر گیرنده انسولین; ACC, acetyl-CoA carboxylase; Adipo-IR, adipose tissue insulin resistance; AUC, area under the curve; FAS, fatty acid synthase; HOMA-IR, the homeostasis model assessment of insulin resistance; IRS, insulin receptor substrate; NEFA, non-esterified fatty aci

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Opioid μ-receptors as new target for insulin resistance

Keywords: IRS، بستر گیرنده انسولین; CNS, Central nervous system; DAG, Diacylglycerol; DOR, δ opioid receptors; GDR, Glucose disposal; GLUT4, Muscle glucose transporters subtype 4 form; IL, Including interleukin; IRS, Insulin receptor substrate; JNK, Jun N-terminal kinase; KOR, κ opioid rece

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Resistin disrupts glycogen synthesis under high insulin and high glucose levels by down-regulating the hepatic levels of GSK3β

Keywords: IRS، بستر گیرنده انسولین; IRβ, insulin receptor β; IRS, insulin receptor substrate; PI3K, phosphoinositide 3-kinase; Akt, protein kinase B; GSK-3β, glycogen synthase kinase-3β; PEPCK (also called PCK1), phosphoenolpyruvatecarboxykinase; SOCS, suppressors of cytokine signaling; TNF

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Acute effects of different diet compositions on skeletal muscle insulin signalling in obese individuals during caloric restriction

Keywords: IRS، بستر گیرنده انسولین; BMI, body mass index; CTRC, Clinical Translational Research Center; EGTA, ethylene glycol tetraacetic acid; FFA, free fatty acids; HF/LC, high fat/low carbohydrate hypocaloric diet; IL-6, interleukin-6; IRS, insulin receptor substrate; LF/HC, low fat/high

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance

Keywords: IRS، بستر گیرنده انسولین; WD, Western Diet; T2DM, type 2 diabetes mellitus; CVD, cardiovascular disease; CKD, chronic kidney disease; PI3-K, phosphatidylinositol 3 kinase; Akt, protein kinase B; ERK1/2, extracellular regulated kinases ½; IRS, insulin receptor substrate; JNK, C-Jun

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Chronic treatment with myo-inositol reduces white adipose tissue accretion and improves insulin sensitivity in female mice

Keywords: IRS، بستر گیرنده انسولین; ANOVA, analysis of variance; BSA, bovine serum albumin; BW, body weight; GTT, glucose tolerance test; HOMA-IR, homeostasis model assessment of insulin resistance; IgG, immunoglobulin G; IPG(s), insulin phosphoglycan(s); IRS, insulin receptor substrate; IT

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Insulin/insulin-like growth factor (IGF) stimulation abrogates an association between a deubiquitinating enzyme USP7 and insulin receptor substrates (IRSs) followed by proteasomal degradation of IRSs

Keywords: IRS، بستر گیرنده انسولین; IRS, insulin receptor substrate; IGF, insulin-like growth factor; PI3K, phosphatidylinositol 3-kinase; SH2, src homology region 2; USP7, ubiquitin specific protease 7; Grb2, growth factor receptor-bound protein 2; Erk, extracellular signal-regulated kinas

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Loss of the Prader–Willi obesity syndrome protein necdin promotes adipogenesis

Keywords: IRS، بستر گیرنده انسولین; CM, conditioned medium; Dkk, Dickkopf; Irs, insulin receptor substrate; MAGE, melanoma antigen gene; MDI, isobutylmethylxanthine, dexamethasone, and insulin; MEFs, mouse embryonic fibroblasts; PWS, Prader–Willi syndromeGenetic obesity; Mouse embryonic fib

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2

Keywords: IRS، بستر گیرنده انسولین; BMM, bone marrow-derived macrophages; GM-CSF, granulocyte macrophage-colony stimulating factor; IRS, insulin receptor substrate; MFI, mean fluorescence intensity; MAPK, mitogen-activated protein kinase; M-CSF, macrophage-colony stimulating factor; PBMC, p

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Protein acetylation mechanisms in the regulation of insulin and insulin-like growth factor 1 signalling

Keywords: IRS، بستر گیرنده انسولین; Akt/PKB, protein kinase B; HAT, histone acetyltransferase; HDAC, histone deacetylase; IGF-1, insulin-like growth factor; IIS, insulin/insulin-like signalling; IRS, insulin receptor substrate; mTOR, mammalian target of rapamycin; PCAF, p300/CBP associated

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

New 4-[(5-arylidene-2-arylimino-4-oxo-3-thiazolidinyl)methyl]benzoic acids active as protein tyrosine phosphatase inhibitors endowed with insulinomimetic effect on mouse C2C12 skeletal muscle cells

Keywords: IRS، بستر گیرنده انسولین; Enzyme inhibitor; Diabetes mellitus; Obesity; Protein tyrosine phosphatase; Insulinomimetic agent; Molecular dockingDM2, type 2 diabetes mellitus; 2-DOG, 2-deoxyglucose; IR, insulin receptor; IRS, insulin receptor substrate; JAK, Janus kinase; LMW-PTP, lo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Beneficial effects of IKKε-deficiency on body weight and insulin sensitivity are lost in high fat diet-induced obesity in mice

Keywords: IRS، بستر گیرنده انسولین; WAT, white adipose tissue; ER, endoplasmic reticulum; IKK, inhibitor of kB kinase; IRS, insulin receptor substrate; NF-κB, nuclear factor-κB; LPS, lipopolysaccharide; TBK1, TRAF-associated NF-κB activator-binding kinase 1; HFD, high fat diet; KO, knockout

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Insulin receptor substrates form high-molecular-mass complexes that modulate their availability to insulin/insulin-like growth factor-I receptor tyrosine kinases

Keywords: IRS، بستر گیرنده انسولین; IRS, insulin receptor substrate; IGF, insulin-like growth factor; SH2, src homology region 2; Bt2cAMP, dibutyryl cyclic adenosine 3′, 5′-monophosphate; TNF, tumor necrosis factor; PI 3-kinase, phosphoinositide 3-kinase; Grb2, growth factor receptor-bound

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Insulin-induced neurite-like process outgrowth: Acceleration of tau protein synthesis via a phosphoinositide 3-kinase∼mammalian target of rapamycin pathway

Keywords: IRS، بستر گیرنده انسولین; DMSO, dimethyl sulfoxide; ERK, extracellular signal-regulated kinase; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; GSK-3, glycogen synthase kinase-3; IGF-I, insulin-like growth factor-I; IRS, insulin receptor substrate; MEK, mitogen-activated protein

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Diethyl hexyl phthalate-induced changes in insulin signaling molecules and the protective role of antioxidant vitamins in gastrocnemius muscle of adult male rat

Keywords: IRS، بستر گیرنده انسولین; DEHP, diethyl hexyl phthalate; IR, insulin receptor; IRS, insulin receptor substrate; AS160, Akt substrate 160; GLUT4, glucose transporter protein 4; LPO, lipid peroxidation; RIA, radioimmunoassay; RT-PCR, reverse transcriptase-polymerase chain reaction;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

NOX3-derived reactive oxygen species promote TNF-α-induced reductions in hepatocyte glycogen levels via a JNK pathway

Keywords: IRS، بستر گیرنده انسولین; DPI, diphenyliodinium; IRS, insulin receptor substrate; JNK, Jun N-terminal kinase; l-NAME, NG-nitro-l-arginine methyl ester; NOX, NADPH oxidase; PKC, protein kinase C; RNAi, RNA interference; ROS, reactive oxygen species; TNF-α, tumor necrosis factor-αTN

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Modulation of hypothalamic PTP1B in the TNF-α-induced insulin and leptin resistance

Keywords: IRS، بستر گیرنده انسولین; IR, insulin receptor; IRS, insulin receptor substrate; icv, intracerebroventricular infusion; PTP1B, protein tyrosine phosphatase 1BPTP1B; Insulin action; Insulin signaling

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Acute exercise reverses aged-induced impairments in insulin signaling in rodent skeletal muscle

Keywords: IRS، بستر گیرنده انسولین; Akt, protein kinase B/Akt; IkBα, IkappaBalpha Kinase; IR, insulin receptor; IRS, insulin receptor substrate; JNK, c-jun N-terminal Kinase; PI3-K, phosphatidylinositol 3-kinase; PTP-1B, protein tyrosine phosphatase 1B; SIRT1, silent mating type information

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Effect of zinc on regulation of insulin-like growth factor signaling in human androgen-independent prostate cancer cells

Keywords: IRS، بستر گیرنده انسولین; PC-3, human prostatic carcinoma cell line; IGFs, insulin-like growth factors; IGF-IR, IGF type I receptor; IGFBPs, IGF binding proteins; IRS, Insulin receptor substrate; IR, insulin receptor; PI-3 K, phosphatidyl inositol-3 kinase; ERK, extracellular regu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

3β-taraxerol of Mangifera indica, a PI3K dependent dual activator of glucose transport and glycogen synthesis in 3T3-L1 adipocytes

Keywords: IRS، بستر گیرنده انسولین; EAE, Ethyl acetate extract; IRβ, insulin receptor β; IRS, insulin receptor substrate; IRTK, insulin receptor tyrosine kinase; PI3K, phosphotidyl inositol 3-kinase; PKB, protein kinase B; GLUT4, glucose transporter; GSK3 β, Glycogen synthase kinase 3β; NBT

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Membrane microdomains and insulin resistance

Keywords: IRS، بستر گیرنده انسولین; DRM, detergent resistant membrane microdomains; Cav1, caveolin-1; IR, insulin receptor; IRS, insulin receptor substrate; SAT-I, GM3 synthase; FRAP, fluorescence recovery after photobleeching; GEM, glycosphingolipid-enriched microdomainsGanglioside; GM3; I

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

The curious case of aging plasticity in honey bees

Keywords: IRS، بستر گیرنده انسولین; HPG, hypopharyngeal glands; IIS, insulin/insulin-like signaling; ILP, insulin-like peptide; IRS, insulin receptor substrate; QTL, quantitative trait lociSenescence; Social behavior; Care-giving; Sibling; Vitellogenin; Insulin-like signaling

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1β and suppressor of cytokine signalling-1 in mouse pancreatic beta cells

Keywords: IRS، بستر گیرنده انسولین; FoxO, Forkhead family of transcription factors; IL-1β, Interleukin-1β; IL-1R, Interleukin-1β receptor; IFN-γ, γ-interferon; IR, Insulin receptor; IRS, Insulin receptor substrate; JAK, Janus-kinase; NF-κB, Nuclear factor-κB; PKB/Akt, Protein kinase B; SOCS

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Angiotensin-induced EGF receptor transactivation inhibits insulin signaling in C9 hepatic cells

Keywords: IRS، بستر گیرنده انسولین; Ang II, angiotensin II; AT1R, angiotensin type 1 receptor; EGF, epidermal growth factor; GPCRs, G protein-coupled receptors; GSK-3, glycogen synthase kinase-3; IRS, insulin receptor substrate; IR, insulin receptor; mTOR, mammalian target of rapamycin; PI3

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Insulin increase in MAP kinase phosphorylation is shifted to early time-points by overexpressing APS, while Akt phosphorylation is not influenced

Keywords: IRS، بستر گیرنده انسولین; APS, Adaptor protein with a PH and SH2 domain; CAP, c-Cbl associated protein; CHO-IR, Chinese hamster ovary cells-overexpressing the insulin receptor; IRS, insulin receptor substrate; MAPK, Mitogen activated protein kinase; PH, Pleckstrin Homology; PtdIns

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Peroxynitrite mediates muscle insulin resistance in mice via nitration of IRβ/IRS-1 and Akt

Keywords: IRS، بستر گیرنده انسولین; BSA, bovine serum albumin; ECL, enhanced chemiluminescence; HFD, high-fat diet; iNOS, inducible nitric oxide synthase; IP, immunoprecipitation; IR, insulin receptor; IRS, insulin receptor substrate; NC, normal chow; NOS, nitric oxide synthase; NT, nitroty

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

In vitro effect of gliclazide on DNA damage and repair in patients with type 2 diabetes mellitus (T2DM)

Keywords: IRS، بستر گیرنده انسولین; Endo III, endonuclease III; Fpg, formamidopyrimidine-DNA glycosylase; GPx, glutathione peroxidase; IRS, insulin receptor substrate; PI3K, phosphatidylinositol 3-kinase; ROS, reactive oxygen species; SODs, uperoxide dismutase; T2DM, type 2 diabetes mellitu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Involvement of the ERK1/2 MAPK pathway in insulin-induced S6K1 activation in avian cells

Keywords: IRS، بستر گیرنده انسولین; 4E-BP1, eukaryotic initiation factor 4E binding protein; Akt or PKB, protein kinase B; eEF2, eukaryotic elongation factor 2; ERK, extracellular signal-regulated protein kinase; IRS, insulin receptor substrate; MAPK, mitogen-activated protein kinase; S6K1,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

A role of FRK in regulation of embryonal pancreatic beta cell formation

Keywords: IRS، بستر گیرنده انسولین; ERK, extracellular-signal regulated kinase; FRK, fyn-related-kinase; IGF1R, insulin-like growth factor 1 receptor; IRS, insulin receptor substrate; PAP, peroxidase anti-peroxidase; PBS, phosphate buffered saline; PI3K, phosphatidyl inositol 3 kinase; PKB,

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Increased Rho Kinase Activity in a Taiwanese Population With Metabolic Syndrome

Keywords: IRS، بستر گیرنده انسولین; BMI, body mass index; HBSS, Hanks’ balanced salt solution; HDL-C, high-density lipoprotein cholesterol; hs-CRP, high-sensitivity C-reactive protein; IL, interleukin; IRS, insulin receptor substrate; MBS, myosin binding subunit; MetS, metabolic syndrome; R

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Human, but not rat, IRS1 targets to the plasma membrane in both human and rat adipocytes

Keywords: IRS، بستر گیرنده انسولین; GFP, green fluorescent protein; HA, hemagglutinin; IR, insulin receptor; IRS, insulin receptor substrate; PH, pleckstrin homology; PTB, phosphotyrosine binding; SH2, Src homology 2Insulin receptor substrate; Human; Rat; Insulin; Plasma membrane; Signaling

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

The nuclear localization of SOCS6 requires the N-terminal region and negatively regulates Stat3 protein levels

Keywords: IRS، بستر گیرنده انسولین; SOCS, suppressors of cytokine signaling; STAT, signal transducer and activator of transcription; JAK, Janus kinase; SH2, Src homology 2; CIS, cytokine-inducible SH2-containing protein; IR, insulin receptor; IRS, insulin receptor substrate; GFP, green fluo

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Glucose enhances protein tyrosine phosphatase 1B gene transcription in hepatocytes

Keywords: IRS، بستر گیرنده انسولین; PTP, protein tyrosine phosphatase; PTP1B, protein tyrosine phosphatase 1B; PKC, protein kinase C; TK, tyrosine kinase; IR, insulin receptor; IRS, insulin receptor substrate; TC-PTP, T-cell-PTP; LAR, leukocyte antigen receptor phosphatase; DMEM, Dulbecco's

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

The depletion of cellular mitochondrial DNA causes insulin resistance through the alteration of insulin receptor substrate-1 in rat myocytes

Keywords: IRS، بستر گیرنده انسولین; IRS, insulin receptor substrate; GLUT4, facilitative glucose transporter isoform 4; PI3K, phosphatidylinositol 3-kinase; PDK-1, 3-phosphoinositide-dependent protein kinase-1; Akt2/PKB, protein kinase BmtDNA; GLUT4; Insulin resistance; IRS-1; Akt2/PKB

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Metabolic stress in insulin’s target cells leads to ROS accumulation – A hypothetical common pathway causing insulin resistance

Keywords: IRS، بستر گیرنده انسولین; FFA, free fatty acids; IL, interleukin; IRS, insulin receptor substrate; JNK, c-Jun NH(2)-terminal kinase; MAPK, mitogen-activated protein kinase; NFκB, nuclear factor kappa B; PKC, protein kinase C; ROS, reactive oxygen species; TNF, tumour necrosis fact

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Glucose-Dependent Insulinotropic Polypeptide Enhances Adipocyte Development and Glucose Uptake in Part Through Akt Activation

Keywords: IRS، بستر گیرنده انسولین; ANTGIP, GIPR antagonist; GIP, glucose-dependent insulinotropic polypeptide; GIPR, GIP receptor; cAMP, cyclic adenosine monophosphate; GLUT-4, glucose transporter-4; IBMX, 3-isobutyl-1-methylxanthine; IRS, insulin receptor substrate; PKB, protein kinase B;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Selective modulation of the CAP/Cbl pathway in the adipose tissue of high fat diet treated rats

Keywords: IRS، بستر گیرنده انسولین; HFD, high-fat diet; WAT, white adipose tissue; 2DG, 2-deoxy-D-[1-14C] glucose; IR, insulin receptor; IRS, insulin receptor substrate; PI3-K, phosphatidylinositol 3-kinase; Akt, protein kinase B; Cbl, casitas b-lineage lymphoma; CAP, Cbl-associated protein

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Role of aquaporin-7 in the pathophysiological control of fat accumulation in mice

Keywords: IRS، بستر گیرنده انسولین; AQP, aquaporin; BAT, brown adipose tissue; FABP, fatty acid binding protein; FATP, fatty acid transporter protein; FFA, free fatty acids; GK, glycerol kinase; HSL, hormone-sensitive lipase; IRE, insulin response element; IRS, insulin receptor substrate; P

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Dehydroepiandrosterone increases β-cell mass and improves the glucose-induced insulin secretion by pancreatic islets from aged rats

Keywords: IRS، بستر گیرنده انسولین; Akt, protein kinase B, homologous to v-AKT; BetaIRKO, β-cell specific insulin receptor knockout mice; DHEA, dehydroepiandrosterone; IR, insulin receptor; IRS, insulin receptor substrate; PI 3-kinase, phosphoinositide 3-kinase; PPARα, peroxisome proliferat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Emerging role of protein kinase B/Akt signaling in pancreatic β-cell mass and function

Keywords: IRS، بستر گیرنده انسولین; cdk4, cyclin-dependent kinase 4; IGFI, Insulin-like growth factor; IKB, Protein kinase B; IRS, insulin receptor substrate; PI3K, phosphoinositide 3-kinase; PIP3, phosphatidylinositol (3,4,5)P3 phosphate; PH, pleckstrin homologyAkt; PKB; Islets; β-Cell mas

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Emerging role of protein kinase B/Akt signaling in pancreatic β-cell mass and function

Keywords: IRS، بستر گیرنده انسولین; cdk4, cyclin-dependent kinase 4; IGFI, Insulin-like growth factor; IKB, Protein kinase B; IRS, insulin receptor substrate; PI3K, phosphoinositide 3-kinase; PIP3, phosphatidylinositol (3,4,5)P3 phosphate; PH, pleckstrin homologyAkt; PKB; Islets; β-Cell mas

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Leptin and its role in hippocampal synaptic plasticity

Keywords: IRS، بستر گیرنده انسولین; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolopropionic acid; DIC, days in culture; IRS, insulin receptor substrate; JAKS, janus tyrosine kinases; LFS, low frequency stimulation; LTD, long-term depression; LTP, long-term potentiation; MAPK, mitogen-activate

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Lipid phosphatases as a possible therapeutic target in cases of type 2 diabetes and obesity

Keywords: IRS، بستر گیرنده انسولین; GSK, glycogen synthase kinase; IRS, insulin receptor substrate; PI3-kinase, phosphatidyl inositol 3-kinase; PKC, protein kinase C; PTEN, phosphatase and tensin homolog deleted on chromosome ten; SHIP2, src homology 2 domain containing inositol 5′-phosphat

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Ubiquitous Activation of Ras and Jak/Stat Pathways in Human HCC

Keywords: IRS، بستر گیرنده انسولین; CIS, cytokine-inducible SH2-protein; GTP, guanosine triphosphate; HCC, hepatocellular carcinoma; HCCb, hepatocellular carcinoma with better prognosis; HCCp, hepatocellular carcinoma with poorer prognosis; IRS, insulin receptor substrate; Jak, Janus kinase

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Knock-down of LAR protein tyrosine phosphatase induces insulin resistance

Keywords: IRS، بستر گیرنده انسولین; IGF, insulin-like growth factor; IR, insulin receptor; IRS, insulin receptor substrate; LAR, leukocyte common antigen-related protein tyrosine phosphatase; PTP, protein tyrosine phosphataseInsulin receptor; Protein tyrosine phosphatase; LAR; Protein kinas

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه