Keywords: Mucosal immunity; oral tolerance; dendritic cells; regulatory T cells; allergy; ALDH; Aldehyde dehydrogenase; APC; Antigen-presenting cell; BALF; Bronchoalveolar lavage fluid; cDC; Conventional dendritic cells; CFA; Complete Freund adjuvant; DC; Dendritic
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Keywords: AA; Adjuvant-induced arthritis; BCTD; Bhsp65 C-terminal determinants; Bhsp65; Mycobacterial heat-shock protein 65; CIA; Collagen-induced arthritis; EAE; Experimental autoimmune encephalomyelitis; EAU; Experimental autoimmune uveitis; FLS; Fibroblast-like
Keywords: Immunotherapy; mechanisms; allergic rhinitis; allergic asthma; long-term tolerance; T cells; B cells; type 2 innate lymphoid cells; IgE-FAB; biomarkers; Breg; Regulatory B; C1Q; Component 1Q; CRTH2; Chemoattractant receptor-homologous molecule expressed
Keywords: DAMP; danger-associated molecular pattern; GWAS; genome-wide association studies; IL; interleukin; iNOS; inducible nitric oxide synthase; iTreg; inflammatory suppressing inducible regulatory T cells; LPS; lipopolysaccharide; MHC; major histocompatibility;
Keywords: Ag; antigen; APC; antigen presenting cell; AQP4; aquaporin 4; BDNF; brain-derived neurotrophic factor; CD; cluster of differentiation; CCL; C-C ligand; chABC; chondroitinase ABC; CNS; central nervous system; COX; cyclooxygenase; CTLA-4; cytotoxic T lymp
Keywords: Oral tolerance; food allergy; mucosal immunology; immunotherapy; regulatory T; CT; Cholera toxin; CTLA-4; Cytotoxic T lymphocyte-associated antigen 4; DBPCFC; Double-blind, placebo-controlled food challenge; DC; Dendritic cell; FoxP3; Forkhead box prote
Keywords: Food allergy; microbiome; microbiota; regulatory TÂ cells; tolerance; anaphylaxis; IgE; 16S rDNA; IL-4 receptor; Foxp3; Forkhead box protein 3; GF; Germ free; HC-AN; Hierarchical clustering-average-neighbor; IL-4R; IL-4 receptor; iTreg; Induced regulatory
Keywords: SLE; systemic lupus erythematosus; iTreg; induced regulatory T cells; H; histone; HSCT; hematopoietic stem cell transplantation; LAP; latency associated peptide; DEX; dexamethasone; HCQ; hydroxychloroquine; RA; retinoic acid; 1,25(OH)2D3; 1,25-dihydroxyvi
Human Colonic Myofibroblasts Promote Expansion of CD4+ CD25high Foxp3+ Regulatory T Cells
Keywords: Inflammation; Stromal Cells; Inflammatory Bowel Disease; Immune Regulation; Immune Response; CMF; colonic myofibroblasts/fibroblasts; DC; dendritic cell; IL; interleukin; iTreg; inducible T regulatory cells; MHC; major histocompatibility complex; mRNA; me
Ci8 short, a novel LPS-induced peptide from the ascidian Ciona intestinalis, modulates responses of the human immune system
Keywords: LPS; LipoPolySaccharide; PBMCs; Peripheral Blood Mononuclear Cells; MHC; Major Histocompatibility Complex; ZAP-70; 70 kDa TCR ζ chain Associated Protein kinase; TCR; T Cell Receptor; iTreg; induced regulatory T cells; LAP; TGF-β1/Latency Associated Pro
rhPLD2 inhibits airway inflammation in an asthmatic murine model through induction of stable CD25+ Foxp3+ Tregs
Keywords: DXM; dexamethasone; Foxp3; forkhead box protein 3; HBEpCs; human bronchial epithelial cells; TSDR; Treg cell specific demethylationâregion; NF-kB; nuclear factor kB; rhPLD2; recombinant human phosphplipase D2; Treg; CD4+CD25+ Foxp3+ regulatory T; nTreg;
Regulatory T Cells Mediate Local Immunosuppression in Lymphedema
Keywords: ALND; axillary lymph node dissection; CHS; contact hypersensitivity; DC; dendritic cell; nTreg; natural regulatory T cell; iTreg; induced regulatory T cell; Treg; regulatory T cell;
FOXOs in cancer immunity: Knowns and unknowns
Keywords: 2B4; CD244 molecule; AKT or PKB; protein kinase B; APCs; antigen-presenting cells; ARG1; arginase 1; BEC; blood endothelial cell; BLNK; B cell Linker protein; BMP; bone morphogenetic protein; BTK; Bruton tyrosine kinase; C/EBP; CCAAT/enhancer-binding prot
γδ T cells are associated with inflammation and immunopathogenesis of leprosy reactions
Keywords: M. leprae; Mycobacterium leprae; MDT; Multi Drug Therapy; TT; Tuberculoid; LL; Lepromatous Leprosy; RR; Reversal Reaction; ENL; Erythema nodosum leprosum; T1R; Type 1 Reaction; T2R; Type 2 Reaction; CMI; Cell mediate immunity; HI; Humoral Immunity; Th; T
Forkhead box protein 3 demethylation is associated with tolerance induction in peanut-induced intestinal allergy
Keywords: DNA methylation; regulatory T cells; forkhead box protein 3; tolerance; peanut allergy; CFSE; Carboxyfluorescein succinimidyl ester; CNS; Conserved noncoding DNA sequence; DC; Dendritic cell; Foxp3; Forkhead box protein 3; iTreg; Inducible regulatory T; M
Phosphatase wild-type p53-induced phosphatase 1 controls the development of TH9 cells and allergic airway inflammation
Keywords: Allergy; Wip1; TH9 cell development; IL-9; phosphatase; AP-1; Activator protein 1; BAL; Bronchoalveolar lavage; BATF; Basic leucine zipper ATF-like transcription factor; ChIP; Chromatin immunoprecipitation; dLN; Draining lymph node; Foxp3; Forkhead box pr
Immunometabolic profiling of T cells from patients with relapsing-remitting multiple sclerosis reveals an impairment in glycolysis and mitochondrial respiration
Keywords: MS; multiple sclerosis; RR; relapsing remitting; CNS; central nervous system; PBMCs; peripheral blood mononuclear cells; IFN; interferon; Treg; regulatory T cells; Tconv; conventional T cells; iTreg; inducible regulatory T cells; TCR; T cell receptor; sCD
Skin-derived TSLP systemically expands regulatory T cells
Keywords: Regulatory T cells; Thymic stromal lymphopoietin; Vitamin D; Immunotherapy; Tolerance; BM; bone marrow; BrdU; bromodeoxyuridine; DC; dendritic cell; EtOH; ethanol; EAE; experimental autoimmune encephalitis; iTreg; inducible Treg; NOD; non-obese diabetic;
Regulatory T cells in allergic diseases
Keywords: Asthma; food allergy; regulatory TÂ cells; forkhead box P3; IL-4; TH2 cells; CNS; Conserved noncoding region; CTLA-4; Cytotoxic T-lymphocyte-associated protein 4; DC; Dendritic cell; FOXP3; Forkhead box P3; GF; Germ-free; ICOS; Inducible T cell costimulat
IL-4 production by group 2 innate lymphoid cells promotes food allergy by blocking regulatory T-cell function
Keywords: Anaphylaxis; food allergy; IL-4; IL-13; IL-33; group 2 innate lymphoid cells; innate lymphoid cells; nuocytes; mast cells; regulatory TÂ cells; oral tolerance; DT; Diphtheria toxin; DTR; Diphtheria toxin receptor; eGFP; Enhanced green fluorescent protein;
Evaluation of the expression and function of the P2X7 receptor and ART1 in human regulatory T-cell subsets
Keywords: ART1; ADP-ribosyltransferases 1; ART2; ADP-ribosyltransferases 2; ART5; ADP-ribosyltransferases 5; ATP; adenosine tri-phosphate; CFSE; carboxyfluorescein succinimidyl ester; H2O2; hydrogen peroxide; iTreg; inducible regulatory T cells; NAD; nicotinamide a
Increased, but Functionally Impaired, CD14+ HLA-DR-/low Myeloid-Derived Suppressor Cells in Psoriasis: A Mechanism of Dysregulated T Cells
Keywords: iTreg; induced regulatory T cell; MDSC; myeloid-derived suppressor cell; Mo-MDSC; monocytic myeloid-derived suppressor cell; PBMC; peripheral blood mononuclear cell; PD-1; programmed cell death protein 1; PD-L1; programmed death-ligand 1; ROS; reactive ox
Research ArticleHCV epitope, homologous to multiple human protein sequences, induces a regulatory T cell response in infected patients
Keywords: HCV; hepatitis C virus; Treg cells; regulatory T cells; FoxP3; forkhead box P3; nTreg cells; natural Treg cells; iTreg; inducible Treg cells; BLAST; basic local alignment search tool; Teff cells; effector T cells; AbVL; antibody/viral load; ICS; immunogen
Gut microbiota biomodulators, when the stork comes by the scalpel
Keywords: B; Bifidobacterium; CS; Caesarean section; C; Clostridium; CAMPs; commensal associated molecular patterns; DCs; dendritic cells; EPS; exopolysaccharide; ESPACI; European Society for Paediatric Allergology and Clinical Immunology; ESPGHAN; European Society
Induction of antigen specific CD4+CD25+Foxp3+T regulatory cells from naïve natural thymic derived T regulatory cells
Keywords: CD4+CD25+Foxp3+T regulatory cells: Treg; Tolerance; Cytokines; Suppressor; Treg; tTreg; iTreg; Antigen specific; IL-2; IL-4; IL-5; IL-5R; IFN-γ; IL-12; Ts1; Th1-like Treg; Ts2; Th2-like
SAMP1/YitFc Mice Develop Ileitis via Loss of CCL21 and Defects in Dendritic Cell Migration
Keywords: Immune Regulation; Oral Tolerance; CD; Small Intestine; DC; dendritic cell; iTreg; induced regulatory T cells; LP; lamina propria; LYVE-1; lymphatic vessel endothelial receptor 1; mDC; migratory dendritic cell; MLN; mesenteric lymph node; RA; retinoic aci
A role for impaired regulatory T cell function in adverse responses to aluminum adjuvant-containing vaccines in genetically susceptible individuals
Keywords: Allergy; Aluminum; Asthma; iTreg; nTreg; Treg; Vaccination;
Interleukin 15 and CD4+ T Cells Cooperate to Promote Small Intestinal Enteropathy in Response to Dietary Antigen
Keywords: Gluten Allergy; Treg Cells; Immune Regulation; Mouse Model; CD; celiac disease; DC; dendritic cell; IEL; intraepithelial lymphocyte; IFN; interferon; IL; interleukin; iTreg; regulatory T cell induced in the periphery in response to exogenous antigens; LP;
Grass tablet sublingual immunotherapy downregulates the TH2 cytokine response followed by regulatory T-cell generation
Keywords: Sublingual immunotherapy; regulatory T cells; allergic rhinitis; IgG4; IgE; IL-4; CTLA-4; Cytotoxic T lymphocyte-associated antigen 4; GPS; Grass pollen season; IgE-FAB; IgE-facilitated antigen binding; iTreg; Induced regulatory T; sIgE; Allergen-specif
Mechanisms of allergy and clinical immunologyThe transcription factor Etv5 controls TH17 cell development and allergic airway inflammation
Keywords: TH17 cells; transcription factor; Etv5; epigenetic modifications; allergic inflammation; BAL; Bronchoalveolar lavage; ChIP; Chromatin immunoprecipitation; Foxp3; Forkhead box protein 3; HDM; House dust mite; iTreg; Inducible regulatory T; PMA; Phorbol 12-
Peanut oral immunotherapy results in increased antigen-induced regulatory T-cell function and hypomethylation of forkhead box protein 3 (FOXP3)
Keywords: Food allergy; allergy; oral immunotherapy; peanut; TÂ regulatory cells; desensitization; tolerance; epigenetics; forkhead box protein 3; ai-Treg; Antigen-induced regulatory T; APC; Antigen-presenting cell; CD40L; CD40 ligand; CFSE; Carboxyfluorescein succ
Cytokines affecting CD4+ T regulatory cells in transplant tolerance. Interleukin-4 does not maintain alloantigen specific CD4+CD25+ Treg
Keywords: CPM; Counts per minute; ConAsup; Supernatant from concanavalin A activated spleen cells; IFN-γ; Interferon-gamma; IFNGR; IFN-γ receptor; IL; Interleukin; IL-5Rα; IL-5 receptor alpha, specific for IL-5 binding; iTreg; T regulatory cells induced from CD4
Early T helper cell programming of gene expression in human
Keywords: ChIA-PET; chromatin interaction analysis by paired-end tag sequencing; ChIP; chromatin immunoprecipitation; ChIP-seq; chromatin immunoprecipitation coupled to high-throughput sequencing; iTreg; inducible T regulatory cell, adaptive T regulatory; lincRNA;
Regulation of TGFβ in the immune system: An emerging role for integrins and dendritic cells
Keywords: TGFβ; transforming growth factor β; BMP; bone morphogenetic protein; GDF; growth and differentiation factor; TGFβR; TGFβ receptor; LAP; latency-associated peptide; Treg; regulatory T-cell; nTreg; natural regulatory T-cell; iTreg; induced regulatory T-
What are regulatory T cells (Treg) regulating in cancer and why?
Keywords: TGF-β; transforming growth factor beta; nTreg; natural regulatory T cells; iTreg; inducible regulatory T cells; PGE2; prostaglandin E2; COX2; cyclooxygenase 2; TIL; tumor infiltrating lymphocytes; CTL; cytotoxic T lymphocytes; NK cells; natural killer ce
Mechanisms of Allergic Sensitization to Foods: Bypassing Immune Tolerance Pathways
Keywords: Oral tolerance; Dendritic cell; Adjuvant; Epicutaneous; Innate immunity; iTreg;
Preferential Expression of Integrin αvβ8 Promotes Generation of Regulatory T Cells by Mouse CD103+ Dendritic Cells
Keywords: FoxP3; Signaling; Macrobiota; Immune Regulation; DC; dendritic cell; FACS; fluorescence-activated cell sorting; iTreg; induced regulatory T cell; MLN; mesenteric lymph node; RA; retinoic acid; RT-PCR; reverse-transcription polymerase chain reaction; TGF;
Increase of regulatory T cells and the ratio of specific IgE to total IgE are candidates for response monitoring or prognostic biomarkers in 2-year sublingual immunotherapy (SLIT) for Japanese cedar pollinosis
Keywords: DBPC; double-blind, placebo-controlled; ELISA; enzyme-linked immunosorbent assay; ELISPOT; enzyme-linked immunospot assay; iTreg; induced regulatory T cells; ITT analysis; intention-to-treat analysis; JAU; Japanese allergy unit; N.S.; not significant; OT
The TCR-mediated signaling pathways that control the direction of helper T cell differentiation
Keywords: APC, antigen presenting cells; dnCN, dominant-negative calcineurin; dnRas, dominant-negative Ras; TCR, T cell receptor; Th, helper T; Tg, transgenic; Treg, T regulatoryTh1; Th2; Th17; iTreg; TCR signaling; Functional differentiation
Cellules T régulatrices et lupus érythémateux systémique
Keywords: Treg; Cellule T régulatrice; iTreg; Cellule T régulatrice induite ou adaptative; AICD; Activation-induced cell death; IPEX; Immune dysregulation polyendocrinopathy X-linked syndrome; FoxP3; Forkhead/winged-helix protein 3; Cellules T régulatrices; Lupu
Interleukin 27 signaling pathways in regulation of immune and autoimmune responses
Keywords: Th; helper T cell(s); IL; interleukin; IFN; interferon; STAT; signal transducer and activator of transcription; TNF; tumor necrosis factor; TGF; transforming growth factor; EAE; experimental autoimmune encephalomyelitis; GN; glomerulonephritis; iTreg; ind
T-cell regulation in chronic paranasal sinus disease
Keywords: Chronic rhinosinusitis; FOXP3; nasal polyps; T-cell polarization; TGF-β1; transcription factors; T regulatory cell; CRSsNP; Chronic rhinosinusitis without nasal polyps; CRSwNP; Chronic rhinosinusitis with polyps; FOXP3; Forkhead box P3; IQR; Interquartil