Keywords: 5-HT; 5-hydroxytryptamine; 5-HTT; 5-hydroxytryptamine transporter; AC; adenylyl cyclase; AD; Alzheimer's disease; Akt; protein kinase B; AMPAR; α-amino-3-hydroxy-5-mthhyl-4-isoxazolepropionic acid receptor; apCAM; Aplysia cell adhesion molecules; ASD;
مقالات ISI (ترجمه نشده)
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Keywords: TERT; telomerase reverse transcriptase; RNP; ribonucleoprotein; TR; telomerase RNA; CSCs; cancer stem cells; TEN; telomerase essential N-terminal; TRB; TERT RNA-binding; RT; reverse transcriptase; CTE; C-terminal extension; DAT; dissociates activities of
Keywords: Focal cerebral ischemia; Stroke; Middle cerebral artery occlusion; Macrophage migration inhibitory factor; MIF; JAB1; Sex differences; Estrogen; Inflammation; Mouse;
Chemokines and cytokines on the neuroimmunoaxis: Inner ear neurotrophic cytokines in development and disease. Prospects for repair?
Keywords: BDNF; brain-derived neurotrophic factor; BMP; bone morphogenetic protein(s) (e.g. BMP2, BMP4 etc.); CNS; central nervous system; CCL2; chemokine (C-C) motif ligand 2 (also called MCP1, monocyte chemoattractant protein 1); CCR2; C-C chemokine receptor type
Interferon-Ï regulates prostaglandin release in goat endometrial stromal cells via JAB1 - unfolded protein response pathway
Keywords: Interferon tau; Prostaglandin; JAB1; Unfolded protein response; Endoplasmic reticulum stress;
The role of jab1, a putative downstream effector of the neurotrophic cytokine macrophage migration inhibitory factor (MIF) in zebrafish inner ear hair cell development
Keywords: Mif; jab1; mcp1; Inner ear; Hair cell development; Statoacoustic ganglion; VIII nerve; Zebrafish; Neurotrophic cytokines;
The β-catenin E3 ubiquitin ligase SIAH-1 is regulated by CSN5/JAB1 in CRC cells
Keywords: AP-1; activator protein-1; APC; adenomatous polyposis coli; CK1; casein kinase 1; CoIP; co-immunoprecipitation; CRC; colorectal cancer; CRL; cullin RING E3 ubiquitin ligase; CSN; COP9 signalosome; CSN5; fifth subunit of the CSN; Cul1; cullin-1; GSK-3β; g
Decreased expression and prognostic role of cytoplasmic BRSK1 in human breast carcinoma: Correlation with Jab1 stability and PI3K/Akt pathway
Keywords: BRSK1; Jab1; Breast cancer; Prognosis; PI3K/Akt
Sec6 regulated cytoplasmic translocation and degradation of p27 via interactions with Jab1 and Siah1
Keywords: Rho GDIα; Rho GDP-dissociation inhibitor α; GFP; green fluorescence protein; BrdU; bromodeoxyuridine; 7-AAD; 7-amino-actinomycin D; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; siRNA; small interfering RNA; Siah1; seven in absen
X-linked intellectual disability gene CUL4B targets Jab1/CSN5 for degradation and regulates bone morphogenetic protein signaling
Keywords: CUL4B; Cullin 4B; XLID; X-linked intellectual disability; Jab1; Jun activation domain-binding protein; CSN; the constitutive photomorphogenic-9 (COP9) signalosome; BMP; bone morphogenetic protein; CRLs; the cullin-RING ubiquitin ligases; DWD; DDB1-binding
JAB1 regulates unphosphorylated STAT3 DNA-binding activity through protein–protein interaction in human colon cancer cells
Keywords: JAB1; Unphosphorylated STAT3; Protein–protein interaction; STAT3 DNA-binding activity
Jab1 interacts with brain-specific kinase 2 (BRSK2) and promotes its degradation in the ubiquitin-proteasome pathway
Keywords: BRSK2; Jab1; Degradation; Ubiquitination; Cell cycle arrest;
Role of CSN5/JAB1 in Wnt/β-catenin activation in colorectal cancer cells
Keywords: CSN5; COP9 signalosome; Protein degradation; Cullin-RING-ubiquitin ligase; MIF; p53; APC; adenomatous polyposis coli; CDK; cyclin-dependent kinase; CHX; cycloheximide; COP; constitutive photomorphogenesis; CSN; COP9 signalosome; CRC; colorectal cancer; CR
Huntingtin with an expanded polyglutamine repeat affects the Jab1-p27(Kip1) pathway
Keywords: Huntingtin; Polyglutamine; Jab1; p27(Kip1); Transcriptional deregulation
Aminoguanidine normalizes ET-1-induced aortic contraction in type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats by suppressing Jab1-mediated increase in ETA-receptor expression
Keywords: AG; aminoguanidine; AGEs; advanced glycation end-products; CML; N epsilon-(carboxymethyl) lysine; ECE1; endothelin converting enzyme; ERK; extracellular signal-regulated kinase; ET-1; endothelin-1; ETA-R; endothelin type A receptor; ETB-R; endothelin type
Augmenter of liver regeneration causes different kinetics of ERK1/2 and Akt/PKB phosphorylation than EGF and induces hepatocyte proliferation in an EGF receptor independent and liver specific manner
Keywords: Augmenter of liver regeneration; Human hepatocytes; Liver regeneration; AKT/PKB; ERK1/2; Liver specificity; AP-1; activator protein-1; rhALR; recombinant human augmenter of liver regeneration; EGF; epidermal growth factor; ERK1/2; extracellular signal-reg
JAB1 accelerates mitochondrial apoptosis by interaction with proapoptotic BclGs
Keywords: BclGs, Bcl-Gonad short form; BH3, Bcl-2 homology domain 3; JAB1, c-Jun activation domain binding protein 1; RNAi, RNA interferenceBclGs; JAB1; Bcl-2 family; BH3 domain; Mitochondria apoptosis
Inverse expression of Jun activation domain binding protein 1 and cell cycle inhibitor p27Kip1: influence on proliferation in hepatocellular carcinoma
Keywords: Jab1; p27Kip1; Hepatocellular carcinoma; Immunohistochemistry
Interaction of the stress protein p8 with Jab1 is required for Jab1-dependent p27 nuclear-to-cytoplasm translocation
Keywords: p8; Jab1; p27; Two hybrid; Cell cycle
Adapter protein NRBP associates with Jab1 and negatively regulates AP-1 activity
Keywords: NRBP, nuclear receptor binding protein; Jab1, Jun activation domain-binding protein 1; AP-1, activating protein-1NRBP; AP-1; Signal transduction; Jab1
CSN5/Jab1 inhibits cardiac L-type Ca2+ channel activity through protein–protein interactions
Keywords: CSN5; Jab1; Cardiac myocyte; L-type Ca2+ channel; Protein–protein interactionBSA, bovine serum albumin; CSN5, COP9 signalosome subunit 5; DMEM, Dulbecco's modified Eagle Medium; ER, endoplasmic reticulum; IP, immunoprecipitation; Jab1, Jun activation doma
Depletion of Jab1 inhibits proliferation of pancreatic cancer cell lines
Keywords: Pancreatic cancer; Jab1; RNAi; Growth inhibition; Apoptosis; Myc
Molecular cloning and characterization of human Aph2 gene, involved in AP-1 regulation by interaction with JAB1
Keywords: hAph2; zf-DHHC; Yeast two-hybrid; JAB1; AP-1
The neuronal POU transcription factor Brn-2 interacts with Jab1, a gene involved in the onset of neurodegenerative diseases
Keywords: Brn-2; Neocortex; Interaction protein; Jab1; Neurodegenerative diseases;
Small Jab1-containing subcomplex is regulated in an anchorage- and cell cycle-dependent manner, which is abrogated by ras transformation
Keywords: COP9 signalosome; Cell cycle; Jab1; ras transformation; Cdk inhibitor p27; Anchorage dependence;
Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif
Keywords: C60SMIF; MIF mutant with Cys60 exchanged for Ser; CALC; Cys-Ala-Leu-Cys motif; CSN; COP9 signalosome; CSN5; subunit 5 of COP9 signalosome; IVT; in vitro transcription/translation; FCS; fetal calf serum; JAB1; c-Jun activation domain binding protein-
Human Homologue of Maid Is a Useful Marker Protein in Hepatocarcinogenesis
Keywords: AAF/PH; 2-acetylaminofluorene/partial hepatectomy; AH; adenomatous hyperplasia; CDAA; choline-deficient L-amino acid-defined; DAPI; 4â²,6-diamidino-2-phenyliondole dihydrochloride; DIP1; D-type cyclin-interaction protein 1; GCIP; Grap2 cyclin-D interacti
COPing with hypoxia
Keywords: COP9 signalosome; CSN; Hypoxia; VHL; CSN5; Jab1;
The interaction between HIF-1 and AP-1 transcription factors in response to low oxygen
Keywords: AEC; aortic endothelial cell; bFGF; basic fibroblast growth factor; cAMP; cyclic adenosine 3â²,5â²-monophosphate; CKI; cyclin-dependent kinase inhibitor; CRY1; cryptochrome 1; CYP3A6; cytochrome p450 oxidase 3A6; DEC1; deleted in esophageal cancer 1; 4E