دانلود مقالات ISI درباره کیناز جانوس + ترجمه فارسی

STAT3 Mediates Nilotinib Response in KIT-Altered Melanoma: A Phase II Multicenter Trial of the French Skin Cancer Network

Keywords: کیناز جانوس ; AE; adverse event; AKT; acutely transforming retrovirus AKT8 in rodent T-cell lymphoma; CI; confidence interval; CR; complete response; GIST; gastrointestinal stromal tumors; JAK; Janus kinase; MAPK; mitogen-activated protein kinase; OS; overall survival;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Imatinib prevents lung cancer metastasis by inhibiting M2-like polarization of macrophages

Keywords: کیناز جانوس ; TAM; tumor associated macrophage; CD206; cluster of differentiation 206; BMDMs; bone marrow derived macrophages; Arg1; arginase 1; Mgl2; macrophage galactose N-acetyl-galactosamine specific lectin 2; Mrc1; mannose receptor C-type 1; CDH1; cadherin 1; CCL2

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

A change in structural integrity of c-Kit mutant D816V causes constitutive signaling

Keywords: کیناز جانوس ; JAK; Janus kinase; JM region; juxtamembrane region; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; MD; molecular dynamics; MIHC; Myb-immortalized haemopoietic cells; WT; wild-type c-Kit; WTp; wild-type phosphorylated c-Kit; MT_D816V

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Nesfatin-1 functions as a switch for phenotype transformation and proliferation of VSMCs in hypertensive vascular remodeling

Keywords: کیناز جانوس ; α-SMA; α-smooth muscle actin; BCA; Bicinchoninic acid; CCK-8; Cell counting kit-8; CDK2; cyclin dependent kinase 2; DAPI; 4′,6-diamidino-2-phenylindole; DBP; diastolic blood pressure; DMEM; Dulbecco's modified Eagle's medium; DHE; dhydroethidium; EdU;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

The proinflammatory effects of macrophage-derived NADPH oxidase function in autoimmune diabetes

Keywords: کیناز جانوس ; ABIS; All Babies in Southwest Sweden study; APC; Antigen presenting cells; Arg-1; Arginase 1; CB3; Coxsackievirus strain B3; CB4; Coxsackievirus strain B4; CGD; Chronic granulomatous disease; CSF-1; Colony-stimulating factor 1; AISY; Diabetes Autoimmunity

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Clinical variables and ethnicity may influenced by polymorphism of CAT −262C/T and MnSOD 47C/T antioxidant enzymes in Algerian type1 diabetes without complications

Keywords: کیناز جانوس ; T1D; type1 diabetes; CAT; Catalase; MnSOD; manganese superoxide dismutase; SOD; superoxide dismutase; WHO; World Health Organization; TAHINA; survey Transition And Health Impact in North Africa; INSP; National Institute of Public Health; ROS; Reactive oxy

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

STAT3: The art of multi-tasking of metabolic and immune functions in obesity

Keywords: کیناز جانوس ; Signal transducer and activator of transcription 3; Obesity; Metabolism; Lipid; Immune; AgRP; Agouti-related peptide; AMPK; AMP-activated protein kinase; AOX; acyl-CoA oxidase; ARC; arcuate nucleus; ATGL; adipose triglyceride lipase; BAT; brown adipose ti

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

IAPP in type II diabetes: Basic research on structure, molecular interactions, and disease mechanisms suggests potential intervention strategies

Keywords: کیناز جانوس ; 2DIR; two-dimensional infra-red spectroscopy; AFM; atomic force microscopy; AGE; advanced glycation end; CD; circular dichroism; CGRP; calcitonin gene-related peptides; DMSO; Dimethyl Sulfoxide; EGCG; epigallocatechin gallate; EPR; electron paramagnetic r

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Recent advances of RAF (rapidly accelerated fibrosarcoma) inhibitors as anti-cancer agents

Keywords: کیناز جانوس ; MAPK; RAF inhibitors; Anti-cancer agents; Abl; Abelson murine leukemia viral oncogene; ATP; Adenine triphosphate; Bcl-2; B-cell lymphoma; CNS; Central nervous system; COX-2; Cyclo-oxygenase enzyme-2; CR; Conserved region; CRD; Cysteine-rich domain; DFG; A

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2018 سفارش ترجمه

Protein tyrosine phosphatase conjugated with a novel transdermal delivery peptide, astrotactin 1-derived peptide recombinant protein tyrosine phosphatase (AP-rPTP), alleviates both atopic dermatitis-like and psoriasis-like dermatitis

Keywords: کیناز جانوس ; Atopic dermatitis; psoriasis; transdermal delivery peptide; protein tyrosine phosphatase; T-cell protein tyrosine phosphatase; transcutaneous drug; immunomodulatory protein; AD; Atopic dermatitis; AP; Astrotactin 1-derived peptide; CHS; Contact hypersen

دانلود رایگان متن کامل مقاله ISI 75 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy as a pharmacological target in hematopoiesis and hematological disorders

Keywords: کیناز جانوس ; 3-MA; 3-methyladenine; ALL; acute lymphoblastic leukemia; AMKL; acute megakaryoblastic leukemia; AML; acute myeloid leukemia; AMPK; 5′-adenosine monophosphate-activated protein kinase; APL; acute promyelocytic leukemia; Atg; autophagy-related proteins;

دانلود رایگان متن کامل مقاله ISI 80 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular cloning, transcriptional profiling, and subcellular localization of signal transducer and activator of transcription 2 (STAT2) ortholog from rock bream, Oplegnathus fasciatus

Keywords: کیناز جانوس ; STAT2; signal transducer and activator of transcription 2; JAK; Janus kinase; IL-10; interleukin-10; TYK2; tyrosine kinase 2; IFN; interferon; ISGF3; IFN-stimulated gene factor 3; ISG; IFN-stimulated gene; CREB; cyclic AMP-response element-binding protein

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

JAK/STAT pathway directed therapy of T-cell leukemia/lymphoma: Inspired by functional and structural genomics

Keywords: کیناز جانوس ; JAK/STAT; T-cell malignancy; JAK inhibitor; ATLL; adult T-cell leukemia/lymphoma; γc; common gamma receptor dependent cytokine; HTLV-1; human T-cell lymphotropic virus-1; IL-2/IL-2R; interleukin 2/interleukin 2 receptor; JAK; Janus kinase; JAK3i; Janus k

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Spinal dorsal horn astrocytes: New players in chronic itch

Keywords: کیناز جانوس ; Astrocytes; Spinal dorsal horn; STAT3; Lipocalin-2; Mouse; ATF3; activating transcription factor 3; CNS; central nervous system; CV; conventional; GRP; gastrin-releasing peptide; GRPR; GRP receptor; GFAP; glial fibrillary acidic protein; JAK; Janus kinase

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

The JAK/STAT signaling pathway and photobiomodulation in chronic wound healing

Keywords: کیناز جانوس ; AP; activator protein; ATP; adenosine triphosphate; Ca2+; calcium ions; cAMP; cyclic adenosine monophosphate; Cox; cytochrome c oxidase; Cu; copper; Cyto c; cytochrome c; DNA; deoxyribonucleic acid; ECM; extracellular matrix; EGF; epidermal growth factor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Cinnamic acid derivatives inhibit hepatitis C virus replication via the induction of oxidative stress

Keywords: کیناز جانوس ; Hepatitis C virus; Cinnamic acid; STAT3; Reactive oxygen species; HCV; hepatitis C virus; IFN; interferon; ROS; reactive oxygen species; STAT3; signal transducer and activator of transcription 3; JAK; Janus kinase; IL-6; interleukin-6; OAS3; 2′-5′-oli

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Interleukin-10 inhibits neuroinflammation-mediated apoptosis of ventral mesencephalic neurons via JAK-STAT3 pathway

Keywords: کیناز جانوس ; PD; Parkinson's disease; IL-10; interleukin-10; IL-10R; interleukin-10 receptor; LPS; lipopolysaccharide; TH; tyrosine hydroxylase; TNF-α; tumor necrosis factor-α; BDNF; brain derived neurotrophic factor; JAK; Janus kinase; STAT; signal transducer and a

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Tofacitinib ameliorates inflammation in a rat model of airway neutrophilia induced by inhaled LPS

Keywords: کیناز جانوس ; JAK; Inhaled LPS rat model; Tofacitinib; Lung inflammation; BALF; STAT3; BALF; bronchoalveolar lavage fluid; JAK; janus kinase; LPS; lipopolysaccharide; pSTAT3; phosphorylated STAT3; STAT; signal transducers and activators of transcription; TLR; toll-like

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Tofacitinib, an oral Janus kinase inhibitor, for the treatment of Latin American patients with rheumatoid arthritis: Pooled efficacy and safety analyses of Phase 3 and long-term extension studies

Keywords: کیناز جانوس ; Janus kinase; Latin America; Rheumatoid arthritis; Tofacitinib; Kinasas Janus; Latinoamérica; Artritis reumatoide; Tofacitinib;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The evolutionary divergence of STAT transcription factor in different Anopheles species

Keywords: کیناز جانوس ; STAT; Signal Transducer and Activator of Transcription; JAK; Janus kinase; NJ; Neighbor-Joining; An.; Anopheles; MEGA; Molecular Evolutionary Genetics Analysis; UTR; untranslated region; MYA; million years ago; P. berghei; Plasmodium berghei; SOCS; suppre

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Repigmentation in vitiligo using the Janus kinase inhibitor tofacitinib may require concomitant light exposure

Keywords: کیناز جانوس ; JAK; Janus kinase; narrowband ultraviolet B; nbUVB; phototherapy; ruxolitinib; tofacitinib; vitiligo; BSA; body surface area; CXCL9; C-X-C motif chemokine ligand 9; ELISA; enzyme-linked immunosorbent assay; IFN-γ; interferon gamma; JAK; Janus kinase; nbU

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The good and the bad faces of STAT1 in solid tumours

Keywords: کیناز جانوس ; BAD; Bcl2-associated agonist of cell death; Bcl; B-cell lymphoma; CD; cluster of differentiation; CDK; cyclin-dependent kinase; CTL; cytotoxic T lymphocyte; CUG; cancer upregulated gene; CXCL; C-X-C motive ligand; DC; dendritic cells; DAMP; danger-associa

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Crosstalk between STAT5 activation and PI3K/AKT functions in normal and transformed mammary epithelial cells

Keywords: کیناز جانوس ; Signal transduction; Janus kinase; STAT; Phosphatidylinositol 3-Kinases; Proto-oncogene proteins c-akt; Mammary gland development; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Short communicationDocosahexaenoic acid inhibits IL-6 expression via PPARγ-mediated expression of catalase in cerulein-stimulated pancreatic acinar cells

Keywords: کیناز جانوس ; DAPI; 4′,6-diamidino-2-phenylindole; DCF-DA; dichlorofluorescein diacetate; DHA; docosahexaenoic acid; JAK; Janus kinase; NADPH; nicotinamide adenine dinucleotide phosphate; NF-κB; nuclear factor kappa-B; PPARγ; peroxisome proliferator-activated recep

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

6-Hydroxy-3-O-methyl-kaempferol 6-O-glucopyranoside potentiates the anti-proliferative effect of interferon α/β by promoting activation of the JAK/STAT signaling by inhibiting SOCS3 in hepatocellular carcinoma cells

Keywords: کیناز جانوس ; Kaempferol glucopyranoside; Saussurea stella; Interferon; JAK/STAT; SOCS3; CML; chronic myelogenous leukemia; ERK; extracellular signal-regulated kinase; HCC; hepatocellular carcinoma; JAK; janus kinase; IFN; interferon; ISRE; interferon-sensitive respons

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Research reportPoly-dimensional network comparative analysis reveals the pure pharmacological mechanism of baicalin in the targeted network of mouse cerebral ischemia

Keywords: کیناز جانوس ; Akt; Serine/threonine kinase; BA; Baicalin/baicalein; CM; Concha margaritifera; CNS; Central nervous system; ERK; Extracellular signal-regulated kinase; GPCRs; Caspase-2 and Galpha (q)-specific amine G-protein-coupled receptors; JAK; Janus kinase; JNK; c-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperInnovative drug vehicle for local treatment of inflammatory skin diseases: Ex vivo and in vivo screening of five topical formulations containing poly(lactic acid) (PLA) nanoparticles

Keywords: کیناز جانوس ; PLA; poly(lactic acid); AD; atopic dermatitis; JAK; janus kinase; PBS; phosphate-buffered saline; BSA; bovine serum albumin; PFA; paraformaldehyde; PDI; polydispersity index; NP; nanoparticle; fluoNP; fluorescent nanoparticle; rpm; rotation per minute; EE

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Rapamycin-Sensitive Late-LTP is Enhanced in the Hippocampus of IL-6 Transgenic Mice

Keywords: کیناز جانوس ; ANOVA; analysis of variance; ACSF; artificial cerebral-spinal fluid; CNS; central nervous system; DNA; deoxyribonucleic acid; ERK; extracellularly regulated kinase; fEPSP; field excitatory postsynaptic potential; HFS; high-frequency stimulation; I/O; inpu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Dual Inhibition of Mnk2 and FLT3 for potential treatment of acute myeloid leukaemia

Keywords: کیناز جانوس ; Mnk inhibitor; FLT3 inhibitor; Dual inhibitor; AML; Drug discovery; Anti-leukaemic agent; AML; acute myeloid leukaemia; CDK; cyclin-dependent kinase; eIF; eukaryotic initiation factor; Erk; extracellular signal-regulated kinase; FLT3; Fms-like tyrosine ki

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

JAK-inhibitor tofacitinib suppresses interferon alfa production by plasmacytoid dendritic cells and inhibits arthrogenic and antiviral effects of interferon alfa

Keywords: کیناز جانوس ; CMV; cytomegalovirus; HCV; hepatitis C virus; IFNα; interferon alpha; JAK; Janus kinase; PBMC; peripheral blood mononuclear cells; PDCs; plasmacytoid dendritic cells; RA; rheumatoid arthritis; RASFs; rheumatoid arthritis synovial fibroblasts; SLE; system

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Treatment of Hypereosinophilic Syndrome with Cutaneous Involvement with the JAK Inhibitors Tofacitinib and Ruxolitinib

Keywords: کیناز جانوس ; HES; hypereosinophilic syndrome; JAK; Janus kinase; L-HES; lymphocytic variant HES; STAT; signal transducer and activator of transcription; Th2; T helper type 2;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

BMI1 and MEL18 Promote Colitis-Associated Cancer in Mice via REG3B and STAT3

Keywords: کیناز جانوس ; PcG; Colon Cancer; Ulcerative Colitis; PAP; AOM; azoxymethane; BMI1; BMI1 proto-oncogene, polycomb ring finger; BrdU; 5-bromo-2-deoxyuridine; CAC; colitis-associated cancer; ChIP; chromatin immunoprecipitation; Co-IP; co-immunoprecipitation; DSS; dextran

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Ruxolitinib reverses dysregulated T helper cell responses and controls autoimmunity caused by a novel signal transducer and activator of transcription 1 (STAT1) gain-of-function mutation

Keywords: کیناز جانوس ; STAT1 gain of function; IFN-γ; ruxolitinib; autoimmunity; TH1 cell; TH17 cell; follicular T helper cell; T helper cell polarization; ATG; Anti-thymocyte globulin; BSA; Body surface area; GOF; Gain of function; IC50; Half-maximal inhibitory concentration

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Functional analyses of the interaction of chicken interleukin 23 subunit p19 with IL-12 subunit p40 to form the IL-23 complex

Keywords: کیناز جانوس ; JAK; Janus kinase; STAT; signal transducer and activator of transcription; SOCS; suppressor of cytokine signaling; TYK2; tyrosine kinase 2; NF-κB; nuclear factor kappa B; C/EBP; CCAAT-enhancer-binding proteins; GATA-1; GATA-binding factor 1; AP-1; Activa

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleMACC1 regulates Fas mediated apoptosis through STAT1/3 - Mcl-1 signaling in solid cancers

Keywords: کیناز جانوس ; Solid cancers; MACC1; STAT signaling; Fas mediated apoptosis; Bcl-2 family proteins; MACC1; Metastasis associated in colon cancer 1; CRC; Colorectal cancer; STAT; Signal transducers and activators of transcription; JAK; Janus kinase; Mcl-1; Myeloid cell l

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

The 20 kDa and 22 kDa forms of human growth hormone (hGH) exhibit different intracellular signalling profiles and properties

Keywords: کیناز جانوس ; 22K-GH; 22 kDa growth hormone; 20K-GH; 20 kDa growth hormone; GHR; growth hormone receptor; JAK; Janus kinase; STAT; signal transducers and activators of transcription; 22 kDa GH; 20 kDa GH; Signalling pathway; JAK2-STAT5;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation

Keywords: کیناز جانوس ; HCC; Tumor Progression; Benign; SHH; bex7,8HCA; β-catenin mutated hepatocellular adenoma in exon 7 or 8; bex7,8IHCA; β-catenin mutated inflammatory hepatocellular adenoma in exon 7 or 8; bex3IHCA; β-catenin mutated inflammatory hepatocellular adenoma i

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Analysis of JAK-STAT signaling pathway genes and their microRNAs in the intestinal mucosa of genetically disparate chicken lines induced with necrotic enteritis

Keywords: کیناز جانوس ; JAK; Janus kinase; STAT; signal transducer and activator of transcription; SOCS; suppressor of cytokine signaling; IL; interleukin; RT; reverse transcription; TYK2; tyrosine kinase 2; SH2 (PTPN); src homology 2-containing tyrosine phosphatase 2; PIAS; pro

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

RhoA/ROCK pathway mediates leptin-induced uPA expression to promote cell invasion in ovarian cancer cells

Keywords: کیناز جانوس ; uPA; urokinase plasminogen activator; ObR; leptin receptor; OB-Rb; The long form of leptin receptor; RhoA; Ras homolog gene family, member A; ROCK; Rho-associated coiled-coil-forming protein kinase; siRNA; small interfering RNA; C3; C3 transferase; JAK; J

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

A conserved inhibitory role of suppressor of cytokine signaling 1 (SOCS1) in salmon antiviral immunity

Keywords: کیناز جانوس ; SOCS; JAK/STAT signaling; IPNV; SAV; Interferons; Atlantic salmon; bp; base pair; JAK; Janus kinase; IFN; Interferon; SH2; SRC-homology 2; ESS; extended SH2 domain; KIR; kinase inhibitory region; SOCS; suppressors of cytokine signaling; STAT; Signal Trans

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

The multi-site docking protein Gab1 is constitutively phosphorylated independent from its recruitment to the plasma membrane in Jak2-V617F-positive cells and mediates proliferation of human erythroleukaemia cells

Keywords: کیناز جانوس ; AEBSF; 4-(2-aminoethyl)-benzolsulfonylfluorid; DMEM; Dulbecco's modified Eagle's medium; EGFR; epidermal growth factor receptor; Epo; erythropoietin; EpoR; erythropoietin receptor; Erk; extracellular signal regulated kinase; FCS; fetal calf serum; Gab1; G

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Role of Runx2 in breast cancer-mediated bone metastasis

Keywords: کیناز جانوس ; Runx2; runt-related transcription factor 2; BRC; breast cancer gene; HER; herceptin; ER; estrogen; PR; progesterone; ECM; extra cellular matrix; EMT; epithelial mesenchymal transition; JAK/STAT; Janus Kinase; NFκB; nuclear factor kappa-B; MMP; matrix met

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Oxidized phospholipids exert a dual effect on bile acid-induced CCL2 expression in pancreatic acini

Keywords: کیناز جانوس ; Inflammatory gene expression; Pancreatic acinar cells; PPARγ; Oxidized phospholipids; TLR4; CCL2; chemokine (C-C motif) ligand 2; FA; fatty acid; JAK; janus kinase; JNK-MAPK; c-Jun NH2-terminal kinase mitogen-activated protein kinase; NF-κB; nuclear fac

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

BH3-only protein BIM: An emerging target in chemotherapy

Keywords: کیناز جانوس ; A1; Bcl-2-related protein A1; Apaf-1; Apoptotic protease-activating factor 1; ASK1; Apoptosis Signal Regulated Kinase 1; Bad; Bcl-2 associated agonist of cell death; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-associated X protein; Bcl-2; B-cell l

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Altered expression of interferon-stimulated genes is strongly associated with therapeutic outcomes in hepatitis B virus infection

Keywords: کیناز جانوس ; Chronic hepatitis B; Antiviral therapy; IFN signaling pathway; STAT1; MX; Peg-IFN; pegylated interferon; HBeAg; hepatitis B e antigen; HBsAg; hepatitis B surface antigen; NAs; nucleot(s)ide analogues; CHB; chronic hepatitis B; ETV; entecavir; ISGs; interf

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Nrf2 signaling pathway: Pivotal roles in inflammation

Keywords: کیناز جانوس ; ARE; antioxidant response element; CBP; cAMP-response-element-binding protein binding protein; COX-2; cyclooxygenase 2; Gclc; glutamate cysteine ligase catalytic subunit; Gclm; glutamate cysteine ligase regulatory subunit; GSH; glutathione; HO-1; heme oxy

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Janus kinase 2 activation participates in prostaglandin E2-induced hyperalgesia

Keywords: کیناز جانوس ; Janus kinase; PKC; Inflammatory hyperalgesia; PGE2;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Structure-based design and development of (benz)imidazole pyridones as JAK1-selective kinase inhibitors

Keywords: کیناز جانوس ; Janus Kinase; JAK1 kinase inhibitor; Structure-based design

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Mitochondrial STAT3: Powering up a potent factor

Keywords: کیناز جانوس ; EGF; epidermal growth factor; ETC; Electron Transport Chain; GAS; γ-activated sequence; IκB; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor; JAK; Janus Kinase; LIF; leukemia inhibitory factor; NF-κB; nuclear factor kappa-l

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Sophoraflavanone G from Sophora alopecuroides inhibits lipopolysaccharide-induced inflammation in RAW264.7 cells by targeting PI3K/Akt, JAK/STAT and Nrf2/HO-1 pathways

Keywords: کیناز جانوس ; SG; Sophoraflavanone G; LPS; lipopolysaccharide; NO; nitric oxide; PGE2; prostaglandin E2; iNOS; inducible nitric oxide synthase; COX-2; cyclooxygenase-2; TNF-α; tumor necrosis factor-α; IL-6; interleukin-6; IL-1β; interleukin-1β; PI3K; phosphoinositi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه