دانلود مقالات ISI درباره کیناز جانوس + ترجمه فارسی

The dietary flavonoid myricetin regulates iron homeostasis by suppressing hepcidin expression

Keywords: کیناز جانوس ; AI; anemia of inflammation; BMP; bone morphogenetic protein; ERK; extracellular signal-regulated kinase; ESAs; erythropoiesis-stimulating agents; HAMP; hepcidin antimicrobial peptide; HJV; hemojuvelin; IL-6; interleukin-6; JAK; Janus kinase; LPS; lipopoly

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

tPA promotes cortical neuron survival via mTOR-dependent mechanisms

Keywords: کیناز جانوس ; DIV; days in vitro; JAK; Janus kinase; mTOR; mammalian target of rapamycin; p2; postnatal day 2; PDL; poly-d-lysine; p-S6; phospho-S6; p-STAT3; phosphorylated signal transducer and activator of transcription 3; tPA; tissue plasminogen activator; Tissue pl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Ensemble docking-based virtual screening yields novel spirocyclic JAK1 inhibitors

Keywords: کیناز جانوس ; AUC; area under the (ROC) curve; EF; enrichment factor; FDA; Food and Drug Administration; FPR; false positive rate; HTVS; high throughput virtual screening; JAK; Janus kinase; LLE; lipophilic ligand efficiency; LELP; lipophilicity-corrected ligand effici

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

JAK1/2 Inhibitor Ruxolitinib Controls a Case of Chilblain Lupus Erythematosus

Keywords: کیناز جانوس ; JAK; Janus kinase; LE; lupus erythematosus; MF; myelofibrosis; STAT; signal transducer and activator of transcription;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Cancer development, chemoresistance, epithelial to mesenchymal transition and stem cells: A snapshot of IL-6 mediated involvement

Keywords: کیناز جانوس ; Cytokine; IL-6; Cancer stem cell; Chemoresistance and EMT; MAPK; mitogen-activated protein kinases; STAT3; signal transducer and activator of transcription 3; gp130; glycoprotein 130; C/EBP; CCAAT/enhancer-binding protein; JAK; Janus kinase; PI3K; phospho

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Results from oral gavage carcinogenicity studies of ruxolitinib in Tg.rasH2 mice and Sprague-Dawley (Crl:CD) rats

Keywords: کیناز جانوس ; Ruxolitinib; Jakafi; Jakavi; Janus kinase; JAK; Carcinogenicity; Tg.rasH2;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

STAT3 and SOCS3 regulate NG2 cell proliferation and differentiation after contusive spinal cord injury

Keywords: کیناز جانوس ; CNTF; Ciliary neurotrophic factor; CSPG; Chondroitin sulfate proteoglycan; DAPI; 4′,6-Diamidino-2-phenylindole; EdU; 5-Ethynyl-2′-deoxyuridine; GFAP; Glial fibrillary acidic protein; JAK; Janus kinase; LIF; Leukemia inhibitory factor; NG2; Neural glia

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Epigallocatechin gallate and mitochondria-A story of life and death

Keywords: کیناز جانوس ; ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; ALT; alanine aminotransferase; AMP; adenosine monophosphate; AP-1; activator protein-1; ASK1; apoptosis signal-regulating kinase 1; ATP; adenosine triphosphate; Bax; BCL2-Associated X Protein; Bc

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Crystal Structure of a Complex of the Intracellular Domain of Interferon λ Receptor 1 (IFNLR1) and the FERM/SH2 Domains of Human JAK1

Keywords: کیناز جانوس ; JAK; Janus kinase; IFNAR1; interferon-α receptor 1; IFNLR1; interferon-λ receptor 1; TVMV; tobacco vein mottling virus; TEV; tobacco etch virus; MR; molecular replacement; JAK/STAT signaling; cytokine receptors; Janus kinases; protein-protein interact

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Oncogenic KRAS signaling and YAP1/β-catenin: Similar cell cycle control in tumor initiation

Keywords: کیناز جانوس ; YAP1; Yes; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; eIF4E; eukaryotic translation initiation factor 4E; PI3K; phosphatidylinositide-3-kinase; WNT; Wingless-type mouse mammary tumor virus integration site family m

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Janus kinases and Src family kinases in the regulation of EGF-induced vimentin expression in MDA-MB-468 breast cancer cells

Keywords: کیناز جانوس ; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; EMT; epithelial-mesenchymal transition; FBS; fetal bovine serum; JAK; Janus kinase; NT; non-targeting; PP2; 4-amino-5-(4-clorophenyl)-7-(t-butyl) pyrazolo[3,4-d] pyrimidine; SFK; Src fa

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Modulatory influences of estradiol and other anorexigenic hormones on metabotropic, Gi/o-coupled receptor function in the hypothalamic control of energy homeostasis

Keywords: کیناز جانوس ; 2-AG; 2-arachidonoylglycerol; AgRP; agouti-related peptide; AMPK; AMP-activated protein kinase; ARC; hypothalamic arcuate nucleus; CRH; corticotropin-releasing hormone; DSI; depolarization-induced suppression of inhibition; ERK; extracellular signal-regul

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Interleukin-6/STAT pathway is responsible for the induction of gene expression of REG Iα, a new auto-antigen in Sjögren׳s syndrome patients, in salivary duct epithelial cells

Keywords: کیناز جانوس ; IFN, interferon; IL, interleukin; JAK, Janus kinase; MSG, minor salivary glands; SS, Sjögren׳s syndrome; STAT, signal transducer and activator of transcriptionRegenerating gene; Interleukin-6; Sjögren׳s syndrome; Janus kinase; Signal transducer and activa

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Matrine suppresses proliferation and induces apoptosis in human cholangiocarcinoma cells through suppression of JAK2/STAT3 signaling

Keywords: کیناز جانوس ; Ac-DEVD-CHO; N-acetyl-Asp-Glu-Val-Asp-aldehyde; EGCG; epigallocatechin-3-gallate; IL-6; interleukin-6; JAK; Janus kinase; JC-1; 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimi-dazolylcarbocyanine iodide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-dip

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

C-mannosylation of thrombopoietin receptor (c-Mpl) regulates thrombopoietin-dependent JAK-STAT signaling

Keywords: کیناز جانوس ; Post-translational modification; C-mannosylation; Thrombopoietin receptor; c-Mpl; JAK-STAT; TPO; thrombopoietin; JAK; Janus kinase; STAT; signal transducer and activator of transcription; ECD; extracellular domain;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Acute nitrogen dioxide (NO2) exposure enhances airway inflammation via modulating Th1/Th2 differentiation and activating JAK-STAT pathway

Keywords: کیناز جانوس ; NO2; nitrogen dioxide; MUC5AC; mucin gene; IL-1β; Interleukin-1β; IL-6; Interleukin-6; ICAM-1; intercellular adhesion molecule; Th2; subtype of helper T lymphocyte; JAK; Janus kinase; STAT; signal transducer and activator of transcription; IL-4; Interle

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Mutations leading to constitutive active gp130/JAK1/STAT3 pathway

Keywords: کیناز جانوس ; Inflammatory hepatocellular adenomas; gp130; STAT3; FRK; GNAS; JAK1; HCA; hepatocellular adenoma; IHCA; inflammatory HCA; HCC; hepatocellular carcinoma; STATs; ignal transducer and activator of transcription; JAK; Janus kinase; LGL; large granular lymphoc

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Effects of the I682F mutation on JAK2's activity, structure and stability

Keywords: کیناز جانوس ; JAK; Janus kinase; JH; JAK homology; STAT5s; ignal transducer and activator of transcription 5; B-ALL; B-cell acute lymphoblastic leukemia; MPDs; myeloproliferative disorders; ALL; acute lymphoblastic leukemia; WT; Wild type; ANS; 1-anilino-8-naphthalenes

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Systems biology of IL-6, IL-12 family cytokines

Keywords: کیناز جانوس ; Systems biology; Mathematical modeling; IL-6-type cytokines; Quantitative analyses; Epo; erythropoietin; gp; glycoprotein; hESC; human embryonic stem cells; EGF; epidermal growth factor; ERK; extracellular signal regulated kinase; HGF; hepatocyte growth f

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

IL-10/Janus kinase/signal transducer and activator of transcription 3 signaling dysregulates Bim expression in autoimmune lymphoproliferative syndrome

Keywords: کیناز جانوس ; ALPS; Bim; Bcl-2 pathway; IL-10; BH3 mimetic; ABT-737; T cell homeostasis; double negative T cells; apoptosis; ALPS; Autoimmune lymphoproliferative syndrome; CDR; Complementarity determining region; DNTC; Double negative T cells; IL-10R; IL-10 receptor; J

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Quality control mechanisms in cellular and systemic DNA damage responses

Keywords: کیناز جانوس ; DNA damage; Ageing; Ubiquitin proteasome system; DNA repair; Progeroid syndromes; Genome stability; ARF; adenosine diphosphate ribosylation factor; AT; ataxia telangiectasia; ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; BER; base excis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular and cellular pharmacologyDifferences in gene expression and alterations in cell cycle of acute myeloid leukemia cell lines after treatment with JAK inhibitors

Keywords: کیناز جانوس ; Ruxolitinib (PubChem CID: 25126798); Gandotinib (PubChem CID: 46213929); Fedratinib (PubChem CID: 16722836); Tofacitinib (PubChem CID: 9926791); Janus kinase; JAK inhibitors; Cell cycle; Cyclin D1; Aurora A kinase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Interferon-γ in foam cell formation and progression of atherosclerosis

Keywords: کیناز جانوس ; IFN-γ; interferon-γ; IFNGR; IFN-γ receptor; VSMC; vascular smooth muscle cell; IL; interleukin; LPS; lipopolysaccharide; TNF-α; tumor necrosis factor-α; STAT; signal transducer and activator of transcription; NF-κB; nuclear factor-κB; TLR; Toll-lik

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Leukemia inhibitory factor (LIF)

Keywords: کیناز جانوس ; Leukemia inhibitory factor; JAK/STAT/SOCS; LIF receptor; Embryonic stem cells; Pregnancy; Nerve and muscle; LIF; leukemia inhibitory factor; CNTF; ciliary neurotrophic growth factor; CT1; cardiotrophin 1; CLC; carditrophin-like cytokine; JAK; Janus kinase

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

A Janus Kinase in the JAK/STAT signaling pathway from Litopenaeus vannamei is involved in antiviral immune response

Keywords: کیناز جانوس ; Janus kinase; JAK/STAT pathway; Positive feedback loop; Litopenaeus vannamei; WSSV

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Interleukin-6 enhances acid-induced apoptosis via upregulating acid-sensing ion channel 1a expression and function in rat articular chondrocytes

Keywords: کیناز جانوس ; ASICs; acid-sensing ion channels; ASIC1a; acid-sensing ion channel 1a; AA; adjuvant arthritis; IL-6; interleukin-6; RA; rheumatoid arthritis; JAK; janus kinase; STAT; signal transducer and activator of transcription; MAPK; mitogen-activated protein kinase

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

MAPK-induced Gab1 translocation to the plasma membrane depends on a regulated intramolecular switch

Keywords: کیناز جانوس ; Crk; CT10 regulator of kinase; CRKL; Crk-like protein; ERK; extracellular signal regulated kinase; FCS; foetal calf serum; Gab1; Grb2-associated binder 1; Grb2; growth factor receptor bound protein 2; IL-6; interleukin-6; JAK; Janus kinase; HEK; human emb

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Folic acid mediates activation of the pro-oncogene STAT3 via the Folate Receptor alpha

Keywords: کیناز جانوس ; CNTF(R); Ciliary neurotrophic factor (receptor); EGF; Epidermal growth factor; ERK; Extracellular signal-regulated kinase; FRα; Folate receptor alpha; GPI; glycophosphatidylinositol; IFN; Interferon; IL-6(R); Interleukin 6 (receptor); ISG; Interferon sti

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Permanent uncoupling of male-specific CYP2C11 transcription/translation by perinatal glutamate

Keywords: کیناز جانوس ; CHIP; chromatin immunoprecipitation; CYP; cytochrome P450; GH; growth hormone; GHR; growth hormone receptor; HYPOX; hypophysectomized; JAK; Janus kinase; miRNA; microRNA; MSG; monosodium glutamate; pSTAT5b; phospho signal transducers and activators of tra

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

The plastic response of Manduca sexta to host and non-host plants

Keywords: کیناز جانوس ; Manduca sexta; Herbivore; Transcriptome; Detoxification; Olfactory receptor; Immunity; AM; antennae and maxillae; G; gut with Malpighian tubules; SG; silk gland (labial gland); W; whole insect; P450; cytochrome P450 monooxygenase; GST; glutathione S-trans

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Cardioprotective potential of annexin-A1 mimetics in myocardial infarction

Keywords: کیناز جانوس ; Ac2-26; Cardioprotection; Cardiomyopathy; Formyl peptide receptors; Inflammation; Ischemia-reperfusion; Aβ42; 42-amino acid beta-amyloid peptide; ABC; ATP-binding cassette; Ac2-26; N-terminal-derived annexin-A1 peptide (acetyl-AMVSEFLKQAWIENEEQEYVVQTVK

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Oncostatin M-dependent Mcl-1 induction mediated by JAK1/2-STAT1/3 and CREB contributes to bioenergetic improvements and protective effects against mitochondrial dysfunction in cortical neurons

Keywords: کیناز جانوس ; BH domain; Bcl-2 homology domain; CBP; CREB-binding protein; ChIP; chromatin immunoprecipitation; CHX; cycloheximide; CREB; cAMP-response element-binding protein; DIV; days-in-vitro; DMSO; dimethyl sulfoxide; ERK; extracellular signal-regulated kinase; FC

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2015 سفارش ترجمه

STAT signaling in different breast cancer sub-types

Keywords: کیناز جانوس ; STAT; Signal Transducer and Activator of Transcription; ER; Estrogen Receptor; HER2; human epidermal growth factor 2; TNBC; Triple Negative Breast Cancer; IL; interleukin; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; JAK; Janu

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Short communicationAngoline: A selective IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum

Keywords: کیناز جانوس ; STAT3; signal transducer and activator of transcription protein 3; JAK; Janus kinase; NF-κB; nuclear factor κB; IL-6; Interleukin-6; TNFα; tumor necrosis factor-α; IFN; interferon γ; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Novel α-galactosidase A mutation in patients with severe cardiac manifestations of Fabry disease

Keywords: کیناز جانوس ; Akt; protein kinase B; Bp; base pair; cDNA; DNA complementary to RNA; CT; threshold cycle number; ERK; extracellular signal-regulated kinase; FSGD; fish specific genome duplication; GH; growth hormone; GHR; growth hormone receptor; JAK; Janus kinase; mRNA

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors

Keywords: کیناز جانوس ; JAK inhibitor; Pyrrolo[1,2-b]pyridazine; Janus kinase; JAK3; TYK2;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Scaffold hopping towards potent and selective JAK3 inhibitors: Discovery of novel C-5 substituted pyrrolopyrazines

Keywords: کیناز جانوس ; Kinase inhibitors; Janus kinase; JAK; Structure based drug design; Scaffold hopping; Intramolecular hydrogen bond;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Low expression level of OB-Rb results from constitutive translocational attenuation attributable to a less efficient signal sequence

Keywords: کیناز جانوس ; VCAM-1; vascular endotherial cell adhesion molecule-1; PrP; prion protein; Prl; prolactin; JAK; Janus kinase; STAT; signal transducer and activator of transcription; SRP; signal recognition particle; Dox; doxycycline; TMD; transmembrane domain; PK; protei

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

CDX2 can be regulated through the signalling pathways activated by IL-6 in gastric cells

Keywords: کیناز جانوس ; CDX; caudal type homeobox; ERK; extracellular-signal-regulated-kinase; H. pylori; Helicobacter pylori; IL; interleukin; JAK; Janus kinase; MAPK; mitogen-activated protein kinase; SHP; Src-homology protein tyrosine phosphatase; SOX; SRY-related HMG-box; ST

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

SOCS1 Prevents Graft Arteriosclerosis by Preserving Endothelial Cell Function

Keywords: کیناز جانوس ; endothelial activation; endothelial adhesion molecule; SOCS1; EC; endothelial cell; GA; graft arteriosclerosis; ICAM; intercellular adhesion molecule; JAK; Janus kinase; PECAM; platelet/endothelial cell adhesion molecule; SOCS1; suppressor of cytokine sig

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Adiponectin inhibits leptin-induced oncogenic signalling in oesophageal cancer cells by activation of PTP1B

Keywords: کیناز جانوس ; Adipo; adiponectin; BrdU; bromodeoxyuridine; ELISA; enzyme-linked immunoabsorbant assay; JAK; janus kinase; MMP; matrix metalloproteinase; MTT; 3-(4,5-dimethylthiazol-2-y-l)-2, 5-diphenyltetrazolium bromide; OAC; oesophageal adenocarcinoma; PTP; protein t

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

FLLL31, a derivative of curcumin, attenuates airway inflammation in a multi-allergen challenged mouse model

Keywords: کیناز جانوس ; STAT; signal transducer and activator of transcription; JAK; Janus kinase; LPS; lipopolysaccharide; Con A; concanavalin A; HDM; house dust mite; PBS; phosphate-buffered saline; NO; nitric oxide; Dex; dexamethasone; TNF-α; tumor necrosis factor α; IL; in

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

PTPLAD2 is a tumor suppressor in esophageal squamous cell carcinogenesis

Keywords: کیناز جانوس ; ESCC; esophageal squamous cell carcinoma; JAK; Janus kinase; LOH; loss of heterozygosity; MTT; 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyltetrazolium bromide; PTPLAD; protein tyrosine phosphatase-like A domain; SOCS3; suppressor of cytokine signaling 3; STAT

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The role of JAK-STAT signaling in adipose tissue function

Keywords: کیناز جانوس ; Brown and white adipose; Janus kinase; Immune cell; Cytokine; Tyk2; Obesity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Kilham rat virus-induced type 1 diabetes involves beta cell infection and intra-islet JAK-STAT activation prior to insulitis

Keywords: کیناز جانوس ; Innate immunity; Islets; Janus kinase; Kilham rat virus; LEW1.WR1 rat; Signal transducer and activator of transcription; Type 1 diabetes;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Luteolin sensitizes the antiproliferative effect of interferon α/β by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in can

Keywords: کیناز جانوس ; luteolin; 3′,4′,5,7-tetrahydroxyflavone; IFN; interferon; JAK; Janus kinase; STAT; signal transducer and activator of transcription; ISRE; interferon α-stimulated response element; PDE; phosphodiesterase; cAMP; cyclic adenosine 3′,5′-monophosphat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Reviews and feature articleA molecular perspective on TH2-promoting cytokine receptors in patients with allergic disease

Keywords: کیناز جانوس ; Thymic stromal lymphopoietin; IL-4; IL-13; receptors; cytokines; TH2; allergy; asthma treatment; FNIII; Fibronectin III; IL-4R; IL-4 receptor; IL-7R; IL-7 receptor; IL-13R; IL-13 receptor; JAK; Janus kinase; MMP; Matrix metalloproteinase; STAT; Signal tra

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Study of interferon-β antiviral activity against Herpes simplex virus type 1 in neuron-enriched trigeminal ganglia cultures

Keywords: کیناز جانوس ; HSV-1; Herpes simplex virus type 1; TG; trigeminal ganglion; IFN; interferon; gB; HSV-1 glycoprotein B; Oas; 2′-5′ oligoadenylate synthetase; RNase-L; latent ribonuclease or 2′,5′-oligoisoadenylate synthetase-dependent RNAse; Pkr; double strande

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

A Phase 2 Study of Tofacitinib, an Oral Janus Kinase Inhibitor, in Patients With Crohn's Disease

Keywords: کیناز جانوس ; Tofacitinib; CP-690,550; Crohn's Disease; Randomized Control Trial; AE; adverse event; ANC; absolute neutrophil count; CDAI; Crohn's Disease Activity Index; CI; confidence interval; CRP; C-reactive protein; HDL; high-density lipoprotein; IBDQ; Inflamm

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Oxidative stress impairs multiple regulatory events to drive persistent cytokine-stimulated STAT3 phosphorylation

Keywords: کیناز جانوس ; JAK; Janus kinase; STAT; Signal Transducer and Activator of Transcription; TC-PTP; T-cell protein tyrosine phosphatase; SOCS3; suppressor of cytokine signalling 3; H2O2; hydrogen peroxide; LIF; leukemia inhibitory factor; OSM; oncostatin M; MAPK; mitogen-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه