دانلود مقالات ISI درباره Janus Kinase 2 + ترجمه فارسی

Increased STAT5 signaling in the ring dove brain in response to prolactin administration and spontaneous elevations in prolactin during the breeding cycle

Keywords: JAK2; Janus Kinase 2; STAT5; Signal Transducer and Activator of Transcription 5; pSTAT5; phosphorylated STAT5; ir; immunoreactivity; POA; preoptic area; SCN; suprachiasmatic nucleus of the hypothalamus; PVN; paraventricular nucleus of the hypothalamus; VM

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibitory effects of AG490 on H2O2-induced TRPM2-mediated Ca2+ entry

Keywords: TRPM2; TRPA1; Janus kinase 2; AG490; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

CEP-33779 antagonizes ATP-binding cassette subfamily B member 1 mediated multidrug resistance by inhibiting its transport function

Keywords: ABC; ATP-binding cassette; ABCC1; multidrug resistance-associated protein 1; ABCG2; breast cancer resistance protein; CSCs; Cancer stem cell; DOX; doxorubicin; FTC; fumitremorgin C; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; Rho123; Rhodamine 123; M

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Aspirin-triggered Lipoxin A4 attenuates mechanical allodynia in association with inhibiting spinal JAK2/STAT3 signaling in neuropathic pain in rats

Keywords: ALX; LXA4 receptor; ATL; aspirin-triggered Lipoxin A4; CCI; chronic constriction injury; COX-2; cycloxygenase-2; CSF; cerebral spinal fluid; CT; threshold cycle; DMSO; dimethyl sulfoxide; FITC; fluorescein isothiocyanate; JAK2; Janus Kinase 2; LO; lipoxyg

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells

Keywords: Ace-tubulin; Acetylated-tubulin; ANOVA; analysis of variance; DAPI; 4′,6-diamidino-2-phenylindole; E-cad; E-cadherin; ELISA; enzyme-linked immunosorbent assay; FAK; focal adhesion kinase; FITC; fluorescein isothiocyanate; GAPDH; glyceraldehyde-3-phospha

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The association of the JAK2 46/1 haplotype with non-splanchnic venous thrombosis

Keywords: JAK2; Janus kinase 2; SVT; splanchnic venous thrombosis; non-SVT; non-splanchnic venous thrombosis; MPNs; myeloproliferative neoplasms; SNP; single nucleotide polymorphism; HWE; Hardy-Weinberg equilibrium; AS-PCR; allele-specific polymerase chain reaction

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Critical role of FANCC in JAK2 V617F mutant-induced resistance to DNA cross-linking drugs

Keywords: ATM; ataxia-telangiectasia mutated; Epo; erythropoietin; EpoR; erythropoietin receptor; ET; essential thrombocythemia; FA; Fanconi anemia; JAK2; Janus kinase 2; MPNs; myeloproliferative neoplasms; PMF; primary myelofibrosis; PV; polycythemia vera; RT-PCR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Peroxiredoxin V selectively regulates IL-6 production by modulating the Jak2-Stat5 pathway

Keywords: PrdxV; peroxiredoxin V; LPS; lipopolysaccaride; IL-6; interleukin 6; Jak2; janus kinase 2; Stat5; signal transducer and activator of transcription 5; SOCS1; suppressor of cytokine signaling 1; TNF-α; tumor necrosis factor α; IFN-β; interferon β; RANTE

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Transcriptomic profiling of progesterone in the male fathead minnow (Pimephales promelas) testis

Keywords: 11-KT; 11-ketotestosterone; AKT1; RAC-α serine/threonine-protein kinase; APOE; apolipoprotein E; APP; amyloid β (A4) precursor protein; AR; androgen receptor; BCL2L1; BCL2-like 1; BCL6; B-cell CLL/lymphoma 6; BMP2; bone morphogenetic protein 2; BMP4; bo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Gene expression profiling for analysis acquired oxaliplatin resistant factors in human gastric carcinoma TSGH-S3 cells: The role of IL-6 signaling and Nrf2/AKR1C axis identification

Keywords: AKR1Cs; aldo-keto reductase family members (e.g. AKR1C1, AKR1C2, or AKR1C3); ARE; antioxidant response element; cisplatin; cis-diamminedichloroplatinum(II) (CDDP); ERCC-1; excision repair cross-complementing-1; ERK; extracellular signal-related kinase; FF

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Janus kinase (JAK) 2 V617F mutation as the cause of primary thrombocythemia in acromegaly with severe visceromegaly and divergence between growth hormone and insulin-like growth factor-1 concentrations during the follow-up: causal or casual association?

Keywords: Acromegaly; Growth hormone; Insulin-like growth factor-1; Janus kinase 2; Growth hormone receptor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Anti-atherogenic mechanisms of high density lipoprotein: Effects on myeloid cells

Keywords: HDL; High density lipoprotein; apo; Apolipoprotein; ABC; ATP binding cassette transporter; TLR; Toll like receptor; HSPC; Hematopoietic stem and multipotent progenitor cell; IL; Interleukin; CBS; IL-3 receptor common beta-subunit; GM-CSF; Granulocyte macr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Amino acid residue E543 in JAK2 C618R is a potential therapeutic target for myeloproliferative disorders caused by JAK2 C618R mutation

Keywords: Constitutive activation; Conformational change; Janus kinase 2; Myeloproliferative disorders; Target; Inhibitor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Peroxisome proliferator-activated receptor-γ cross-regulation of signaling events implicated in liver fibrogenesis

Keywords: AdipoR; adiponectin receptor; AMPK; 5′-AMP-activated protein kinase; AP1; activator protein 1; C/EBP; CCAAT/enhancer binding protein; CHB; chronic hepatitis B; Cidea; mitochondrial cell death-inducing DNA fragmentation factor α-like effector A; CTGF; c

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Janus kinase 2 - A novel negative regulator of estrogen receptor α function

Keywords: CA; constitutive active; CDK2; Cyclin dependent kinase 2; CDK7; Cyclin dependent kinase 7; CK2; Casein kinase 2; DCC; dextran-coated charcoal-treated; DNA-PK; DNA-dependent protein kinase; E2; 17β-estradiol; EGFR; Epidermal growth factor receptor; ER; es

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

CIKS (Act1 or TRAF3IP2) mediates Angiotensin-II-induced Interleukin-18 expression, and Nox2-dependent cardiomyocyte hypertrophy

Keywords: Act1; activator of NF-κB; ACM; adult cardiomyocytes; ANF; atrial natriuretic factor; AP-1; activator protein-1; AT1; angiotensin II type 1 receptor; ATRAP; AT1-receptor-associated protein; ARAP1; type 1 Ang II-receptor-associated protein 1; C/EBP; CCAAT/

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Aurora kinase A critically contributes to the resistance to anti-cancer drug cisplatin in JAK2 V617F mutant-induced transformed cells

Keywords: Aurka; Aurora kinase; Epo; erythropoietin; EpoR; erythropoietin receptor; JAK2; Janus kinase 2; MPNs; myeloproliferative neoplasms; RT-PCR; reverse transcriptase-polymerase chain reaction; STAT5; signal transducers and activators of transcription 5; TAE;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Role of Notch and its oncogenic signaling crosstalk in breast cancer

Keywords: 4T1 cells; mouse mammary cancer cell line; ADAM; a disintegrin and metalloprotease; Akt; protein kinase B; ALDH; aldehyde dehydrogenase; ANK; ankyrin; Axin2; the Axin-related protein; BALB/c; an albino, laboratory-bred strain of the house mouse; Bcl-2; B-

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Kudzu root: Traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases

Keywords: ACE2; angiotensin-converting enzyme 2; ADP; adenosine diphosphate; AGE; advanced glycation end-products; APV; DL-2-amino-5-phosphonovaleric acid; AT1; angiotensin II type I receptor; Aβ25-35; β-amyloid; Bcl-2; B-cell leukemia/lymphoma-2; BKCa; large-con

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2011 سفارش ترجمه

Analysis of JAK2 and STAT3 polymorphisms in patients with ankylosing spondylitis in Chinese Han population

Keywords: Janus kinase 2; Signal transducer and activator of transcription 3; Polymorphism; Ankylosing spondylitis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Research ArticleFerroportin disease: A systematic meta-analysis of clinical and molecular findings

Keywords: AUROC; area under the receiver operator curve; ER; endoplasmic reticulum; HIC; hepatic iron concentration; JAK2; Janus Kinase 2; MRI; magnetic resonance imaging; PolyPhen; polymorphism phenotyping; ROC; receiver operator curve; SIFT; sorting intolerant fr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Identification of a novel inhibitor of JAK2 tyrosine kinase by structure-based virtual screening

Keywords: Janus kinase 2; Virtual screening; Inhibitor; Pharmacological evaluation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2

Keywords: Janus kinase 2; JAK2; Structure based design; 2-Amino-pyrazolo[1,5-a]pyrimidines; Polycythemia vera; Kinase inhibitor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Undiagnosed Myeloproliferative Disease in Cases of Intra-Abdominal Thrombosis: The Utility of the JAK2 617F Mutation

Keywords: BCS; Budd-Chiari syndrome; BMB; bone marrow biopsy; CT; computerized tomography; EHPVT; extrahepatic portal vein thrombosis; ET; essential thrombocythemia; JAK2; Janus kinase 2; MPD; myeloproliferative disorder;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Leptin regulated calcium channels of neuropeptide Y and proopiomelanocortin neurons by activation of different signal pathways

Keywords: leptin; patch-clamp; calcium current; POMC; NPY; AgRP; agouti-related peptide; ARC; arcuate nucleus; [Ca2+]i; cytosolic Ca2+ concentration; DMEM; modified Dulbecco's Eagle's medium; DMSO; dimethysulfoxide; HVA; high voltage-activated calcium channel; IH

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Evaluation of “Increased” Hemoglobin in the JAK2 Mutations Era: A Diagnostic Algorithm Based on Genetic Tests

Keywords: CP; congenital polycythemia; Epo; erythropoietin; EPOR; erythropoietin receptor; ET; essential thrombocythemia; HIF; hypoxia-inducible factor; JAK2; Janus kinase 2; MPD; myeloproliferative disorder; p50; oxygen tension at which hemoglobin is 50% saturated

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Erythropoietin is neuroprotective on GABAergic neurons against kainic acid-excitotoxicity in the rat spinal cell cultures

Keywords: Spinal cord; GABAergic neurons; Erythropoietin; Kainic acid; Glutamate decarboxylase 67; Janus kinase 2

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

6-(Methylsulfinyl)hexyl isothiocyanate suppresses inducible nitric oxide synthase expression through the inhibition of Janus kinase 2-mediated JNK pathway in lipopolysaccharide-activated murine macrophages

Keywords: AP-1; activator protein-1; ERK; extracellular signal-regulated kinase 1/2; iNOS; inducible nitric oxide synthase; Jak2; Janus kinase 2; JNK; c-Jun N-terminal kinase; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinase; 6-MITC; 6-(methylsulfiny

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه