Anti-atherogenic mechanisms of high density lipoprotein: Effects on myeloid cells

► HDL can regulate myelopoiesis through ABCA1 and ABCG1. ► HDL can prevent monocyte entry into the atherosclerotic lesion by inhibiting number and activation. ► HDL attenuates neutrophil activation and adhesion in acute models of inflammation. ► HDL modulates macrophage functions including migration, efferocytosis and TLR signaling.