Keywords: COX; cyclooxygenase; DAPI; 4,6-diamidino-2-phenylindole; EDTA; ethylene diamine tetraacetic acid; IκBα; nuclear factor kappa light polypeptide gene enhancer in B cells inhibitor; LPS; lipopolysaccharide; MnPO; median preoptic nucleus; mPGES; microsomal
مقالات ISI (ترجمه نشده)
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Keywords: ACSL4; acyl-CoA synthetase long-chain family member 4; AD; Alzheimer's disease; ARE; antioxidant-responsive element; ANT; adenine nucleotide translocase; AP-1; activator protein-1; ATP; adenosine triphosphate; Bak; Bcl-2 antagonist/killer; BCEC; brain c
Keywords: Retinal ganglion cells; Axon regeneration; Cancer genes; PTEN; Visual system repair mechanisms; AAV; Adeno-associated virus; CNS; Central Nervous System; CNTF; ciliary neurotrophic factor; DLK; dual leucine zipper kinase; DRG; dorsal root ganglion; EGFR;
Keywords: CRP; C-reactive protein; HDL; high density lipoprotein; LDL; low density lipoprotein; PPARγ; peroxisome proliferator activated receptor-γ; DPP-4; dipeptidyl peptidase-4; GLP-1; glucagon like peptide-1; TRIB3; tribbles homolog 3; ATF-4; activating transc
Keywords: C3G; cyanidin-3-glucoside; COX; cyclooxygenase; DADS; diallyl disulfide; EC; endothelial cell; EGCG; epicatechin-3-gallate and epigallocatechin-3-gallate; EGFR; epidermal growth factor receptor; eNOS; endothelial nitric oxide synthase; FGFR; fibroblast gr
Keywords: 4E-BP; 4E binding protein; AP-1; activator protein-1; Ad-AH; EBV-negative adenocarcinoma cell line; Akt; serine/threonine kinase; ARNT; aryl hydrocarbon receptor nuclear translocator; ATP/ADP; adenosine tri- or diphosphate; CAIX and CAXII; carbonic anhydr
Keywords: EpCAM; epithelial cell adhesion molecule; ER; estrogen receptor; HIF; hypoxia inducible factor; HO-1; heme oxygenase-1; IDO-1; indoleamine 2,3-dioxygenase; FoxP3; Forkhead-Box-Protein P3; IL-10; interleukin 10; MDSC; myeloid-derived suppressor cells; NK c
Keywords: Oral squamous cell carcinoma; Cancer-associated inflammation; COX-2; STAT-3; AP-1; NF-κB; Oral submucous fibrosis; Oral lichen planus;
Keywords: Nicotine exposure; Lactation; Hypothalamus; Neuropeptides; Developmental plasticity; ACTH; adrenocorticotropic hormone; AgRP; agouti-related peptide; ARC; arcuate nucleus; C; control group; CART; cocaine and amphetamine-regulated transcript; CRH; corticot
Hepatic cell sheets engineered from human mesenchymal stem cells with a single small molecule compound IC-2 ameliorate acute liver injury in mice
Keywords: Hepatic cell sheets; Mesenchymal stem cells; Liver regeneration; Wnt/β-catenin signal inhibitor; Acute liver failure; BM-MSCs; bone marrow-derived mesenchymal stem cells; NF-κB; nuclear factor-kappa B; IL-6; interleukin-6; STAT-3; Signal Tranducer and A
Andrographolide, a diterpene lactone from Andrographis paniculata and its therapeutic promises in cancer
Keywords: Andrographolide; Andrographis paniculata; Diterpene lactone; Anticancer; Chemotherapy; Bioactive lactone; ACS; American Chemical Society; AKT; activated protein kinase; Andro; Andrographolide derivative or conjugate; AP-1; activator protein-1; Cdk; Cyclin
Reduced substrate stiffness promotes M2-like macrophage activation and enhances peroxisome proliferator-activated receptor γ expression
Keywords: PPARγ; Peroxisome proliferator-activated receptor γ; ECM; extracellular matrix; TGF-β; transforming growth factor-β; PI3K; phosphoinositide 3-kinase; F-actin; filamentous-actin; TNF-α; tumor necrosis factor-α; IL; interleukin; FCS; fetal calf serum;
Curcumin synergizes with the endocannabinoid reuptake inhibitor OMDM-2 in human MCF-7 breast cancer and U-87 glioblastoma cells
Keywords: Î9-THC; Delta-9-tetrahydrocannabinol; 2-AG; 2-arachidonoylglycerol; AEA; Anandamide; BCL2; B-cell CLL/lymphoma 2; CB-1; Cannabinoid receptor 1; CB-2; Cannabinoid receptor 2; CI; Combination Index; CXCR4; chemokine receptor type 4; DDS; Drug delivery syst
27-Hydroxycholesterol induces invasion and migration of breast cancer cells by increasing MMP9 and generating EMT through activation of STAT-3
Keywords: 27HC; 27-hydroxycholesterol; MMPs; matrix metalloproteinases; E2; estradiol; ER; estrogen receptor; EMT; epithelial-mesenchymal transition; ZEB1; zinc finger E-box-bindingprotein-1; STAT-3; signal transducer and activator of transcription 3; GREB1; growth
BiologySTAT3 Expression in Host Myeloid Cells Controls Graft-versus-Host Disease Severity
Keywords: Bone marrow transplantation; Graft-versus-host disease; STAT-3; Myeloid cells;
Sodium butyrate regulates Th17/Treg cell balance to ameliorate uveitis via the Nrf2/HO-1 pathway
Keywords: NaB; sodium butyrate; EAU; experimental autoimmune uveitis; Nrf2; nuclear factor erythroid 2 -related factor 2; HO-1; heme oxygenase-1; DLN; draining lymphoid nodes; Treg cells; CD4Â +Â T regulatory cells; Foxp3; Forkhead box protein 3; STAT-3; signal tra
Blueberry and malvidin inhibit cell cycle progression and induce mitochondrial-mediated apoptosis by abrogating the JAK/STAT-3 signalling pathway
Keywords: Apoptosis; Blueberry; Cell cycle; Hamster buccal pouch carcinogenesis; Malvidin; STAT-3;
Interleukin 17 regulates SHP-2 and IL-17RA/STAT-3 dependent Cyr61, IL-23 and GM-CSF expression and RANKL mediated osteoclastogenesis by fibroblast-like synoviocytes in rheumatoid arthritis
Keywords: Interleukin 17; Fibroblast-like synoviocytes; Rheumatoid arthritis; SHP-2; STAT-3; Osteoclast;
The prenylflavonoid Icaritin enhances osteoblast proliferation and function by signal transducer and activator of transcription factor 3 (STAT-3) regulation of C-X-C chemokine receptor type 4 (CXCR4) expression
Keywords: Osteoblast; Icaritin; CXCR4; STAT-3; Anabolic therapeutic;
Porphyromonas gingivalis-stimulated macrophage subsets exhibit differential induction and responsiveness to interleukin-10
Keywords: MÏs; macrophages; IL-10; interleukin-10; IL-10R; interleukin-10 Receptor; TNFα; tumour necrosis factor-α; CP; chronic periodontitis; PG-LPS; porphyromonas gingivalis lipopolysaccharide; TLR; toll-like receptor; ET; endotoxin tolerance; STAT-3; signal t
Differential expression of transcription factors NF-κB and STAT3 in periodontal ligament fibroblasts and gingiva of healthy and diseased individuals
Keywords: Periodontal disease; Cell biology; Fibroblast; Transcription factor; NF-kappa B; STAT-3;
The translocator protein (18Â kDa) and its role in neuropsychiatric disorders
Keywords: 3α-HSD; 3α-hydroxysteroid dehydrogenase; 3β-HSD; 3β-hydroxysteroid dehydrogenase/Î5âÎ4; AIF; apoptosis inducing factor; AD; Alzheimer's disease; ANT; adenine nucleotide translocator; AP-1; activator protein 1; APAF-1; apoptotic peptidase activat
Leptin receptor overlapping transcript (LepROT) gene participates in insulin pathway through FoxO
Keywords: 20E; 20-Hydroxyecdysone; S; Dimethyl sulfoxide; FBS; Fetal bovine serum; H. armigera; Helicoverpa armigera; HaEpi; H. armigera epidermal cell line; IGF; Insulin/insulin-like growth factor; IR; Insulin receptor; IRS; Insulin receptor substrate; JAK2; Janus
Resveratrol Inhibited Non-small Cell Lung Cancer Through Inhibiting STAT-3 Signaling
Keywords: Resveratrol; A549 cells; STAT-3; Apoptosis; Proliferation;
Regulators of mitochondrial complex I activity: A review of literature and evaluation in postmortem prefrontal cortex from patients with bipolar disorder
Keywords: BD; bipolar disorder; DHEA; Dehydropiandrosterone; DJ-1; protein deglycase; DOPAC 3,4; dihydroxyphenylacetic acid; FMN; flavine mononucleotide; Grx2; glutaredoxin 2; GSH; glutathione; 6-OHDA; 6-hydroxydopamine; IMP-2; insulin-like growth factor 2 [IGF2] m
Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment
Keywords: APRIL; a proliferation-inducing ligand; ATM; ataxia telangiectasia mutated; BAFF; B-cell activating factor; BAFFR; BAFF receptor; BAG6; BCL2-associated athanogene 6; BCMA; B-cell maturation antigen; BCL2; B-cell lymphoma 2; BCR; B cell receptor; bFGF; bas
Protective and immunomodulatory effect of flos Lonicerae japonicae by augmenting IL-10 expression in a murine model of acute lung inflammation
Keywords: Flos Lonicerae japonicae; Lung inflammatorn; Interleukin-10; Interleukin-6; NF-κB; Sp1; STAT-3;
Hsp90/Cdc37 assembly modulates TGFβ receptor-II to act as a profibrotic regulator of TGFβ signaling during cardiac hypertrophy
Keywords: Hsp90; Heat shock protein 90; Cdc37; Cell division cycle 37; AngII; Angiotensin II; TGFβ; Transforming growth factor β; ECM; Extracellular matrix; TβR-I; Transforming growth factor β receptor-I; TβR-II; Transforming growth factor β receptor-II; 17AA
A novel stereo bioactive metabolite isolated from an endophytic fungus induces caspase dependent apoptosis and STAT-3 inhibition in human leukemia cells
Keywords: HMC; (R)-5-hydroxy-2-methylchroman-4-one; MTT; 3-(4,5-Dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide; PARP-1; Poly(ADP-Ribose) Polymerase-1; PI; propidium iodide; Rh-123; Rhodamine-123; Z-VAD-fmk; benzyloxycarbonyl-Val-Ala-Asp fluoro-methyl-ketone
Central acylated ghrelin improves memory function and hippocampal AMPK activation and partly reverses the impairment of energy and glucose metabolism in rats infused with β-amyloid
Keywords: GOAT; ghrelin O-acyltransferase; GHSR; growth hormone secretagogue receptor; LV; lateral ventricle; ICV; intracerebroventricular; AD-G; Acyl-ghrelin ICV infusion; AD-DES-G; Des-acyl-ghrelin ICV infusion; AD-C; phosphate buffered saline ICV infusion; Non-A
Human S100A9 potentiates IL-8 production in response to GM-CSF or fMLP via activation of a different set of transcription factors in neutrophils
Keywords: S100A9; NF-κB; CREB-1; STAT-3; STAT-5; Neutrophil
Modulation of vascular smooth muscle cell phenotype by STAT-1 and STAT-3
Keywords: STAT-1; STAT-3; Smooth muscle cell; Phenotype; Oncostatin-M;
Down-regulation of miRNA-204 by LMP-1 enhances CDC42 activity and facilitates invasion of EBV-associated nasopharyngeal carcinoma cells
Keywords: Nasopharyngeal carcinoma; Epstein-Barr virus; Latent membrane protein 1; miR-204; Cdc42; Stat-3;
Interleukin 18 activates MAPKs and STAT3 but not NF-κB in hippocampal HT-22 cells
Keywords: IL-18; Hippocampus; Brain; HT-22; STAT-3; Signaling; IL-18Rα; IL-18Rβ; Isoforms; NF-κB
GLP-1 promotes angiogenesis in human endothelial cells in a dose-dependent manner, through the Akt, Src and PKC pathways
Keywords: GLP-1; Glucagon-Like Peptide 1; HCAECs; Human Coronary Artery Endothelial Cells; HUVECs; Human Umbilical Vein Endothelial Cells; VEGF; Vascular Endothelial Growth Factor; STAT-3; Signal transducer and activator of transcription 3; AMPK; 5' adenosine monop
Use of the anti-inflammatory cytokine interleukin-11 to reverse HIV-1gp120 repression of a natural killer cell line
Keywords: HIV-1; NK cells; gp120; IL-11; Cytotoxicity; IFN-γ; NK-92MI; STAT-3; Apoptosis; Bcl-XL;
Dexamethasone down-regulates the inflammatory mediators but fails to reduce the tissue injury in the lung of acute pancreatitis rat models
Keywords: Adhesion molecules; Chemokines; Glucocorticoids; Pulmonary damage; ANOVA; analysis of variance; ARDS; acute respiratory distress syndrome; cDNA; complementary deoxyribonucleic acid; CINC; cytokine-induced neutrophil chemoattractant; ICAM-1; intercellular
Opposing roles of STAT-1 and STAT-3 in regulating vascular endothelial growth factor expression in vascular smooth muscle cells
Keywords: VEGF; STAT-3; STAT-1; HIF-1α; Oncostatin-M; Smooth muscle cell
The regulatory effect of veratric acid on NO production in LPS-stimulated RAW264.7 macrophage cells
Keywords: Veratric acid; iNOS; NF-κB; MAPKs; STAT-1; STAT-3; GSK-3β;
A Phase 2 Trial of Flavopiridol (Alvocidib) and Cisplatin in Platin-Resistant Ovarian and Primary Peritoneal Carcinoma: MC0261
Keywords: Cyclin dependent kinase; CDK; Stat-3
Herbal medicines for the prevention of alcoholic liver disease: A review
Keywords: ACC; acetyl-CoA carboxylase; ACLY; ATP-citrate lyase; ALD; alcoholic liver disease; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AMPK; AMP-activated protein kinase; AST; aspartate aminotransferase; AOX; acyl-CoA oxidase; CAT; catalase; COX-2;
Anti-atherogenic mechanisms of high density lipoprotein: Effects on myeloid cells
Keywords: HDL; High density lipoprotein; apo; Apolipoprotein; ABC; ATP binding cassette transporter; TLR; Toll like receptor; HSPC; Hematopoietic stem and multipotent progenitor cell; IL; Interleukin; CBS; IL-3 receptor common beta-subunit; GM-CSF; Granulocyte macr
Inhibition of STAT-3 results in greater cetuximab sensitivity in head and neck squamous cell carcinoma
Keywords: STAT-3; EGFr; Head and neck cancer; Radiation;
Research ReportIL-10 directly protects cortical neurons by activating PI-3 kinase and STAT-3 pathways
Keywords: IL-10; Neuroprotection; Oxygen-glucose deprivation; Glutamate; STAT-3; AKT;
Oncostatin M is expressed in atherosclerotic lesions: A role for Oncostatin M in the pathogenesis of atherosclerosis
Keywords: Oncostatin M; Smooth muscle cell; Atherosclerosis; Carotid plaques; ApoEâ/â; STAT-1; STAT-3;
Prognostic significance of IL-8-STAT-3 pathway in astrocytomas: Correlation with IL-6, VEGF and microvessel morphometry
Keywords: IL-8; STAT-3; IL-6; VEGF; astrocytoma
Paucity of genotype-phenotype correlations in STAT3 mutation positive Hyper IgE Syndrome (HIES)
Keywords: Autosomal dominant hyper-IgE syndrome(AD-HIES); Job's syndrome; STAT-3; Genotype-phenotype;
Galactose specific adhesin of enteroaggregative E. coli induces IL-8 secretion via activation of MAPK and STAT-3 in INT-407 cells
Keywords: EAEC; Adhesin; Signaling; MAPK; STAT-3; IL-8
Synergistic benefits of erythropoietin and simvastatin after traumatic brain injury
Keywords: Akt/PKB; a serine/threonine protein kinase B; BBB; Blood Brain Barrier; BrdU; Bromodeoxyuridine; BDNF; Brain-derived neurotrophic factor; CCI; Controlled cortical impact; CREB; CyclicAMP responsive element binding protein; CNS; Central nervous system; eNO
Inhibition of STAT-3 results in radiosensitization of human squamous cell carcinoma
Keywords: STAT-3; Radiosensitization