Keywords: Cocoa flavanols; Endothelium; Oxidative injury; Signaling pathways; Cardiovascular diseases; AKT/PKB; protein kinase B; AMPK; adenosine monophosphate-activated protein kinase; DAF-FM-DA; 4-amino-5-methylamino-2,7-difluorofluorescein diacetate; DCFH-DA; 2â
مقالات ISI (ترجمه نشده)
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Keywords: GI50; half-maximal cell growth inhibitory concentration; Hesperetin; Hesperetin-7-butyrate; Apoptosis; JNKs;
Keywords: KCs; kupffer cells; JNKs; C-Jun N-terminal kinases; MAPKs; mitogen-activated protein kinases; CCR2; C-C motif chemokine receptor 2; ATMs; Adipose tissue macrophages; HFD; high-fat diet; MLK3; mixed-lineage kinase 3; PPAR; peroxisome proliferator-activat
Keywords: ABCA; ATP-binding cassette transporter; AIM; Apoptosis inhibitor of macrophage; APC; antigen-presenting cell; ASC; apoptotic speck protein containing a caspase recruitment domain; AT; adipose tissue; ATM; AT macrophage; BLT; leukotriene B4 receptor; BM; b
Keywords: AA; arachidonic acid; ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; ANT; adenine nucleotide translocase; Apaf-1; apoptotic protease activating factor-1; ATP; adenosine triphosphate; ATP-ase; ATP synthase;
Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; GRP78; glucose-regulated protein 78; ERKs; extracellular signal-regulated kinases; JNKs; c-Jun NH2-terminal protein kinases; SAPKs; stress-activated protein kinases; MAPKKs; MAPK kinases; MKP; MAP
The multifaceted role of glutathione S-transferases in cancer
Keywords: Glutathione-S transferase; Carcinogenesis; Biomarkers; Drug resistance; Tumor suppressor; AD; Aricaidine; AP-1; Activator protein 1; ASK1; Apoptosis signal-regulating kinase; CSC; cancer stem cells; EGFR; Epidermal growth factor receptor; GSH; glutathione
Berberine confers neuroprotection in coping with focal cerebral ischemia by targeting inflammatory cytokines
Keywords: TTC; 23,5-triphenyltetrazolium chloride; MCAO; middle cerebral artery occlusion; p-AKT; phosphorylated Protein kinase B; pGSK; phosphorylated Glycogen synthase kinase; pCREB; phosphorylated cAMP response element-binding protein; NF-κB; nuclear factor-κB
Antileukemic effect of paclitaxel in combination with metformin in HL-60 cell line
Keywords: APL; acute promyelocytic leukemia; AML; acute myeloid leukemia; PML/RARα; promyelocytic leukemia/retinoic acid receptor α; ATRA; all-trans retinoic acid; ATO; arsenic trioxide; T2DM; Type 2 Diabetes Mellitus; mTORC1; rapamycin complex 1; AMPK; AMP-activ
Activation of NPY-Y2 receptors ameliorates disease pathology in the R6/2 mouse and PC12 cell models of Huntington's disease
Keywords: Aβ; beta-amyloid; ABC; avidin-biotin complex; BBB; blood brain barrier; BDNF; brain derived neurotrophic factor; BSA; bovine serum albumin; CREB; cAMP response element binding protein; cDNA; complementary deoxyribonucleic acid; DAB, 3; 3-diaminobenzidine
Redox regulation of proteasome function
Keywords: Abcd1; ATP binding cassette subfamily D member 1; AD; Alzheimer's disease; ALD; adrenoleukodystrophy; ALS; amyotrophic lateral sclerosis; AP-1; activator protein-1; APP; amyloid precursor protein; CNS; central nervous system; DDI; DNA-damage inducible 1;
Cancer development, chemoresistance, epithelial to mesenchymal transition and stem cells: A snapshot of IL-6 mediated involvement
Keywords: Cytokine; IL-6; Cancer stem cell; Chemoresistance and EMT; MAPK; mitogen-activated protein kinases; STAT3; signal transducer and activator of transcription 3; gp130; glycoprotein 130; C/EBP; CCAAT/enhancer-binding protein; JAK; Janus kinase; PI3K; phospho
High glucose and hyperglycemic sera from type 2 diabetic patients impair DC differentiation by inducing ROS and activating Wnt/β-catenin and p38 MAPK
Keywords: DCs; dendritic cells; DM2; type 2 diabetes; ROS; reactive oxygen species; MAPKs; mitogen-activated protein kinases; PAMPs; pathogen associated molecular patterns; DAMPs; damage associated molecular patterns; TCF/LEF; T-cell factor/lymphoid enhancer factor
Cross-talk between EPAS-1/HIF-2α and PXR signaling pathway regulates multi-drug resistance of stomach cancer cell
Keywords: EPAS-1; Endothelial PAS domain-containing protein 1; PXR; Pregnane X Receptor (PXR); MDR; multi-drugs resistance; CYP3A4; cytochromes P450 3A4; HIF-2α; hypoxia-inducible transcription factors; ARNT; aryl hydrocarbon receptor nuclear translocator; HRE; hy
Age-related activation of MKK/p38/NF-κB signaling pathway in lung: From mouse to human
Keywords: ALI; acute lung injury; ANOVA; analysis of variance; BALF; bronchoalveolar lavage fluid; COPD; chronic obstructive pulmonary disease; DAB; 3, 3â²-diaminobenzidine tetrahydrochloride; DAPI; 4â², 6-diamidino-2-phenylindole; DMSO; dimethyl sulphoxide; ERKs
Neuroprotective changes of thalamic degeneration-related gene expression by acupuncture in an MPTP mouse model of parkinsonism: Microarray analysis
Keywords: MPTP; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; DA; Dopamine; 6-OHDA; 6-Hydroxydopamine; TBS; Tris-buffered saline; TH; tyrosine hydroxylase; SDS-PAGE; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; PVDF; polyvinyl
Negative regulation of human U6 snRNA promoter by p38 kinase through Oct-1
Keywords: PMA; phorbol 12-myristate 13-acetate; snRNA; small nuclear RNA; RNA Pol III; RNA polymerase III; PSE; proximal sequence element; DSE; distal sequence element; SNAPc; snRNA activating-protein complex; MAPK; mitogen-activated protein kinase; ERKs; extracell
Up-regulation of cyclin D1 by JNK1/c-Jun is involved in tumorigenesis of human embryo lung fibroblast cells induced by a low concentration of arsenite
Keywords: CDK; cyclin-dependent kinase; HELF; human embryo lung fibroblast; JNKs; Jun-N-terminal kinases; MAPKs; mitogen activated protein kinases; NF-κB; nuclear factor kappa B; PI-3Ks; phosphoinositide 3-Kinases; Rb; retinoblastoma; Arsenite; Cell cycle; Jun-N-t
The KDEL receptor induces autophagy to promote the clearance of neurodegenerative disease-related proteins
Keywords: KDEL receptor; ER stress; neurodegenerative disease-related proteins; autophagy; ALS; amyotrophic lateral sclerosis; ARF1; ADP ribosylation factor 1; ARF1-GAP; ARF1 GTPase-activating protein; ATG5; autophagy-related gene 5; BIP; binding immunoglobulin pro
c-Jun N-terminal kinase (JNK) signaling: Recent advances and challenges
Keywords: Ago; Argonaute; DELFIA; Dissociation Enhanced Lathanide Fluoro-Immuno Assay; D-JNKI-1; cell-permeable JIP1-derived JNK inhibitory peptide-1 (D-amino acids); ELISA; enzyme-linked immunosorbent assays; ERK; extracellular signal-regulated kinase (ERK); FITC;
Jun signalling in the epidermis: From developmental defects to psoriasis and skin tumors
Keywords: bZip, basic leucine zipper; EGFR, epidermal growth factor receptor; EGF, epidermal growth factor; GM-CSF, granulocyte-macrophage colony stimulating factor; G-CSF, granulocyte colony stimulating factor; HB-EGF, heparin-binding epidermal growth factor; JNKs
Involvement of JNKs and p38-MAPK/MSK1 pathways in H2O2-induced upregulation of heme oxygenase-1 mRNA in H9c2 cells
Keywords: Heme oxygenase-1; MSK1; JNKs; p38-MAPK; Oxidative stress
Cellular neuroscienceLipopolysaccharide plus 12-o-tetradecanoylphorbol 13-acetate induction of migration and invasion of glioma cells in vitro and in vivo: Differential inhibitory effects of flavonoids
Keywords: invasion; migration; LPS; TPA; flavonoids; MMP-9; DMSO; dimethyl sulfoxide; ECM; extracellular matrix; ERKs; extracellular regulated protein kinases; iNOS; inducible nitric oxide synthase; JNKs; c-Jun N-terminal kinases; KAE; kaempferol; LPS; lipopolysacc
Morin inhibits 12-O-tetradecanoylphorbol-13-acetate-induced hepatocellular transformation via activator protein 1 signaling pathway and cell cycle progression
Keywords: TPA; 12-O-tetradecanoylphorbol-13-acetate; AP-1; activator protein 1; MAP; mitogen-activated protein; ATCC; American Type Culture Collection; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; DMEM; Dulbecco modified Eagle medium; FBS; fet
Inhibition of epidermal growth factor-induced cell transformation by tannins
Keywords: AP-1; activator protein 1; BME; basal medium Eagle; DMSO; dimethylsulfoxide; DTT; dithiothreitol; EBV-EA; Epsten-Barr virus early antigen; EGCG; (â)-epigallochatechin-3-gallate; EGF; epidermal growth factor; EGFR; EGF receptor; ERKs; extracellular-sig
Quercetin, but not rutin and quercitrin, prevention of H2O2-induced apoptosis via anti-oxidant activity and heme oxygenase 1 gene expression in macrophages
Keywords: HO-1; heme oxygenase 1; SnPP; tin protoporphyrin; CO; carbon monoxide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; NBT; nitroblue tetrazolium; BCIP; 5-bromo-4-chloro-3-indolyl phosphate; RT-PCR; reverse transcriptase-polymerase cha