Keywords: AM; adrenomedulin; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMY; amylin; AT; angiotensin type; β-CCT; beta-carboline-3-carboxylate-t-butyl ester; CT; calcitonin; CTR; calcitonin receptor; CLR; calcitonin receptor-like receptor; DZ; di
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Keywords: ABCA1; ATP-binding cassette transporter; ACOG; American College of Obstetricians and Gynecologists; ACSM; American College of Exercise Medicine; AMPK; AMP-activate protein kinase; ADA; American Diabetes Association; BMI; body mass index; BMR; Basal metabo
Keywords: aR'; activity coefficient ratio; CDC; complete depolarization cocktail; ÎÏM; mitochondrial membrane potential; ÎÏP; plasma membrane potential; FCCP; carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone; GSIS; glucose-stimulated insulin secretion; KA
Keywords: [Ca2+]i; intracellular calcium concentration; VDCCs; voltage-dependent Ca2Â + channels; ATP; adenosine triphosphate; RyR; ryanodine receptors; BKCa; large conductance calcium-activated K+ channels; KATP; ATP-sensitive K+ channels; KIR; inward rectifier K+
Keywords: [Ca++]i; intracellular Ca2+ concentration; 2ME2; 2-methoxyestradiol, a natural metabolite of estradiol; 4-OH-Tmx; 4-hydroxytamoxifen, a metabolite of Tmx; 5-HT3R; 5-hydroxytryptamine receptor subtype 3; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropio
Keywords: Ach; acetylcholine (Ach); Ad; adrenaline; AKAP; A kinase anchoring protein; Ano1; anoctamin-1 Ca2 +-activated Clâ channel encoded by the ANO1 gene; α-SMA; α-smooth muscle actin; ASMCs; atypical smooth muscle cells; eYFP; enhanced-yellow fluorescent p
Keywords: 6PGDH; 6-phosphogluconate dehydrogenase; KATP; ATP-sensitive K+ channel; ER; endoplasmic reticulum; G6PDH; glucose-6-phosphate dehydrogenase; GC; gas chromatography; GHB; γ-hydroxybutyric acid; GSIS; glucose-stimulated insulin secretion; ICDc; cytosolic
Keywords: KATP; TDP-43; Stroke; VCID; Arteriosclerosis; Lipohyalinosis; Synucleinopathy; NFT; Neuropathology; SUR2; Oldest-old; PART;
Keywords: Heart; Electrophysiology; Mechanics; Sinoatrial node; Atrium; Ventricle; Slow force response; AF; atrial fibrillation; AP; action potential; BR; beating rate; Ca2+; calcium; Clswell; swelling-activated chloride channel; ECC; excitation-contraction couplin
Keywords: GLUT; Glucose transporter; T1DM; Type-1 diabetes mellitus; T2DM; Type-2 diabetes mellitus; PKB/Akt; protein kinase B; GSK-3; glycogen synthase kinase-3; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator-1α; FOXO; forkhead box O; VLDL;
Keywords: ADHD; attention deficit hyperactivity disorder; ALS; amyotrophic lateral sclerosis; ATP; adenosine triphosphate; IRB; institutional review board; KATP; ATP-sensitive potassium;
Keywords: prostate; prostatic hyperplasia; muscle; smooth; calcium channels; interstitial cells of Cajal; α-SMA; α-smooth muscle actin; AMP; peak amplitude; ATP; adenosine triphosphate; ATPase; adenosine triphosphatase; ICC; interstitial cell of Cajal; [K+]o; ext
Keywords: e-5'-NT; 5'-nucleotidase; ADA; adenosine deaminase; ADP; adenosine diphosphate; ADK; adenosine kinase; AR; adenosine receptor; ATP; adenosine triphosphate; AC; adenylate cyclase; AD; Alzheimer's disease; KATP; ATP-sensitive potassium; cAMP; cyclic 3
Keywords: BK; big potassium channel; BN-PAGE; blue native polyacrylamide gel electrophoresis; Cav; voltage-gated calcium; CNG; cyclic nucleotide-gated channels; CRAC; cholesterol binding sites; CTD; cytoplasmic domain; ENaC; epithelial sodium channels; FRET; Först
Keywords: CPG; hypothermic hyperkalemic cardioplegia; DZX; diazoxide; KATP; adenosine triphosphate-sensitive potassium channel; MI; metabolic inhibition; TYR; Tyrode's solution;
Keywords: Gases; Neuroprotective effect; Mechanism; Clinical translation; Research perspectives; AD; Alzheimer's disease; AMPA; alpha-amino-d-hydroxy-5-methyl-4-isoxazole-propionate; Ar; argon; ATA; absolute atmosphere; ATP; adenosine triphosphate; BBB; blood-bra
Keywords: Bcl-2; B cell lymphoma 2; Bcl-xL; B cell lymphoma-extra large; ARE; antioxidant-response element; Cul3; cullin 3; Cyt c; cytochrome c; Drp1; dynamin-related protein 1; ERK; extracellular signal-regulated kinase; GSH; glutathione; GST; glutathione S-tran
The toxic effects of monosodium glutamate (MSG) - The involvement of nitric oxide, prostanoids and potassium channels in the reactivity of thoracic arteries in MSG-obese rats
Keywords: Monosodium glutamate; Nitric oxide; Obesity; Potassium channels; Thromboxane A2; A23187; calcium ionophore; BKCa; Large Conductance Ca2+-activated K+ channels; cGMP; cyclic guanosine monophosphate; COX; cyclooxygenase; EDCF; endothelial derived contractin
Formaldehyde regulates vascular tensions through nitric oxide-cGMP signaling pathway and ion channels
Keywords: Formaldehyde; Thoracic aorta ring; Vascular tension; Ion channels; Signal pathway; 4-AP; 4-aminopyridine; ACh; acetylcholine; l-NAME; NG-nitro-l-arginine methyl ester; ACE; angiotensin-converting enzyme; VSMCs; vascular smooth muscle cells; BKCa; big-cond
ATP-sensitive and maxi potassium channels regulate BRL 37344-induced tocolysis in buffaloes-an in vitro study
Keywords: BRL 37344; KATP; BKCa; Beta3-adrenoceptors; Myometrium;
Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension
Keywords: ADRF; adipocyte-derived relaxing factor; AE; anion exchanger; ATP; adenosine triphosphate; BH4; tetrahydrobiopterin; BKCa; big conductance Ca2+-sensitive K+ channel; CaM; calmodulin; cAMP; cyclic adenosine monophosphate; CAT; cysteine aminotransferase; CB
Existence of ATP sensitive potassium currents on human periodontal ligament cells
Keywords: PDL; human periodontal ligament; RT-PCR; reverse transcriptase polymerase chain reaction; KATP; ATP-sensitive K+ channel; Human periodontal ligament cell; Inside-out patch; KATP channels;
Suppression of adenosine monophosphate-activated protein kinase selectively triggers apoptosis in activated T cells and ameliorates immune diseases
Keywords: Glibenclamide; T lymphocytes; AMPK; KATP; Apoptosis; Contact hypersensitivity; Glibenclamide (PubChem CID: 3488); Compound C (PubChem CID: 11524144); AICAR (PubChem CID: 17513); Cyclosporin A (PubChem CID: 5284373); 5-HD (PubChem CID: 23676659); Cromakali
Glyburide treatment in gestational diabetes is associated with increased placental glucose transporter 1 expression and higher birth weight
Keywords: Glyburide; Placenta; Fetal growth; Pregnancy; Glucose transport; Syncytiotrophoblast; GDM; gestational diabetes mellitus; BMI; body mass index; KATP; ATP-sensitive potassium channel; MVM; microvillous plasma membrane; BM; basal plasma membrane; GLUT; gluc
The synthetic peptide PnPP-19 induces peripheral antinociception via activation of NO/cGMP/KATP pathway: Role of eNOS and nNOS
Keywords: Nitric oxide; PnPP-19; Antinociception; Spider toxin; Pain; NO; nitric oxide; nNOS; Neuronal nitric oxide synthase; eNOS; Endothelial nitric oxide synthase; KATP; ATP-Sensitive potassium channels; cGMP; Cyclic guanosine monophosphate; PGE2; Prostaglandin
Testosterone rapidly increases Ca2+-activated K+ currents causing hyperpolarization in human coronary artery endothelial cells
Keywords: ANOVA; analysis of variance; BKCa; large conductance Ca2+-activated K+ channel; DHT; dihydrotestosterone; DIDS; 4,4â²-diisothiocyanatostilbene-2,2â²-disulfonic acid; DMSO; dimethyl sulfoxide; EET; epoxyeicosatrienoic acid; EGTA; ethylene glycol-bis(β-a
Optimization and evaluation of zein nanoparticles to improve the oral delivery of glibenclamide. In vivo study using C. elegans
Keywords: Glibenclamide; Diabetes; Zein; Nanoparticles; C. elegans; SANS; Controlled release; T2DM; Type II diabetes mellitus; GB; glibenclamide; KATP; ATP-dependent potassium channels; ZN; zein; Lys; lysine; NP; nanoparticles; RSM; Response surface methodology; CC
Research PaperParadoxical lower sensitivity of Locus Coeruleus than Substantia Nigra pars compacta neurons to acute actions of rotenone
Keywords: ACA; N-(p-amylcinnamoyl) anthranilic acid; DA; dopamine; DAergic; dopaminergic; FSCV; fast-scan cyclic voltammetry; KATP; ATP-sensitive potassium channel; LC; Locus Coeruleus; NA; noradrenaline; NAergic; noradrenergic; Non-DAergic; non-dopaminergic; PD; P
Transcribing β-cell mitochondria in health and disease
Keywords: β-Cell; Mitochondria; Islets; Genome-wide association study (GWAS); Insulin secretion; Expression quantitative trait locus (eQTL); ATGL; adipocyte triglyceride lipase; AMPK; AMP-dependent protein kinase; COX; Cytochrome c oxidase; CYTB; Cytochrome b; ERR
Oleate induces KATP channel-dependent hyperpolarization in mouse hypothalamic glucose-excited neurons without altering cellular energy charge
Keywords: ACC; acetyl-CoA carboxylase; AMPK; adenosine 5â²-monophophate-activated protein kinase; AMP-PNP; 5â²-adenylylimidodiphosphate; ARC; arcuate nucleus; CPT1; carnitine palmitolytransferase-1; CSF; cerebrospinal fluid; GE; glucose-excited; GI; glucose-inhib
Mechanisms of the amplifying pathway of insulin secretion in the β cell
Keywords: ABCC8; ATP binding cassette subfamily C member 8; ADCY5; adenylyl cyclase type 5; AICAR; 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside; DPP-IV; dipeptidyl peptidase 4; G6PD; glucose-6-phosphate dehydrogenase; GDH; glutamate dehydrogenase; GIP; gast
Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: GRN, TMEM106B, ABCC9, and KCNMB2
Keywords: CARTS; GWAS; PGRN; KATP; rs704180;
Biomarkers of Insulin for the Diagnosis of Hyperinsulinemic Hypoglycemia in Infants and Children
Keywords: FFA; Free fatty acids; GK; Glucokinase; GST; Glucagon stimulation test; IGFBP-1; Insulin-like growth factor binding protein-1; KATP; Adenosine triphosphate-dependent potassium; LINE; Localized islet cell nuclear enlargement; ROC; Receiver operating curv
Suppression of outward K+ currents by activating dopamine D1 receptors in rat retinal ganglion cells through PKA and CaMKII signaling pathways
Keywords: 4-AP; 4-aminopyridine; AC; adenylate cyclase; Bis IV; bisindolylmaleimide IV; BKCa; large-conductance Ca2+-activated K+ channels; CaMKII; calcium/calmodulin-dependent protein kinase II; CNS; central nervous system; DA; dopamine; DMSO; dimethyl sulfoxide;
The bile acid TUDCA increases glucose-induced insulin secretion via the cAMP/PKA pathway in pancreatic beta cells
Keywords: 6E-CDCA; 6-Ethyl-chedeoxycholic acid; ADP; Adenosine diphosphate; AKT or PTB; Protein kinase B; ATP; Adenosine triphosphate; AUC; Area under curve; BSA; Bovine serum albumin; cAMP; Cyclic adenosine monophosphate; CREB; cAMP response element-binding protei
Disruption of ATP-sensitive potassium channel function in skeletal muscles promotes production and secretion of musclin
Keywords: Action potential; Calcium; Natriuretic peptide; Fatty acid; Endurance; AKT; protein kinase B; ANP; atrial natriuretic peptide; ATP; adenosine triphosphate; CaMKII; calcium/calmodulin-dependent protein kinase II; FOXO1; forkhead box O1 transcription factor
Equol increases cerebral blood flow in rats via activation of large-conductance Ca2+-activated K+ channels in vascular smooth muscle cells
Keywords: ACh; acetylcholine; 4-AP; 4-aminopyridine; ANOVA; analysis of variance; BaCl2; barium chloride; BK; large-conductance, voltage- and Ca2+ -activated K+ channel; BSA; bovine serum albumin; CASMCs; cerebral artery smooth muscle cells; DBP; diastolic blood pr
Tingenone, a pentacyclic triterpene, induces peripheral antinociception due to NO/cGMP and ATP-sensitive K+ channels pathway activation in mice
Keywords: Tingenone; Nitric oxide; KATP; Pain; Antinociception;
Original scientific articleDiazoxide Cardioprotection Is Independent of Adenosine Triphosphate-Sensitive Potassium Channel Kir6.1 Subunit in Response to Stress
Keywords: CPG; hypothermic hyperkalemic cardioplegia; DZX; diazoxide; KATP; adenosine triphosphate-sensitive potassium channel; Kir; potassium inward rectifier; sKATP; sarcolemmal adenosine triphosphate-sensitive potassium channel; SUR; sulfonylurea receptor; T
The molecular mechanisms of sodium metabisulfite on the expression of KATP and L-Ca2+ channels in rat hearts
Keywords: CA; chromosomal aberrations; Ct; threshold cycle; EC; excitation-contraction; FASEB; Federation of American Societies for Experimental Biology; HE; hematoxylin-eosin; KATP; ATP-sensitive K+; Kir6.x; inward-rectifying K+ channel family; L-Ca2+; L-type
KATP-channels play a minor role in the protective hypoxic shut-down of cerebellar activity in eider ducks (Somateria mollissima)
Keywords: aCSF; artificial cerebrospinal fluid; DMSO; dimethyl sulfoxide; I/R; ischemia-reperfusion; KATP; ATP-sensitive potassium; MUA; multi-unit activity; diving; hypoxia; cerebellum; neurons; spontaneous activity; KATP-channels;
Electrophysiologic consequences of KATP gain of function in the heart: Conduction abnormalities in Cantu syndrome
Keywords: α-MHC; α-myosin heavy chain; AV; atrioventricular; AVERP; AV effective refractory period in AV node; CS; Cantu syndrome; DTG; double transgenic; ECG; electrocardiogram; ERP; effective refractory period; GOF; gain of function; Kir; inward rectifier potas
Lipid agonism: The PIP2 paradigm of ligand-gated ion channels
Keywords: AA; arachidonic acid; ASIC; acid-sensing ion channel; ATP; adenosine triphosphate; BK; big conductance potassium channel; Cav; voltage-dependent calcium channel or VDCC; Ci-VSP; Ciona intestinalis voltage-sensitive phosphatase; CoA; coenzyme A; CTD; cytop
Research ReportThe H2S-producing enzyme CSE is dispensable for the processing of inflammatory and neuropathic pain
Keywords: BCA; β-cyanoalanine; CAT; cysteine aminotransferase; CBS; cystathione β-synthase; CSE; cystathionine γ-lyase; DRGs; dorsal root ganglia; H2S; hydrogen sulfide; KATP; ATP-sensitive K+; LPS; lipopolysaccharides; MPST; 3-mercaptopyruvate sulfurtransferase
Prolonged hyperglycemia & hyperinsulinemia increases BDNF mRNA expression in the posterior ventromedial hypothalamus and the dorsomedial hypothalamus of fed female rats
Keywords: ANOVA; analysis of variance; aVMH; anterior ventromedial nucleus of the hypothalamus; BDNF; brain-derived neurotrophic factor; CV; coefficients of variance; DMH; dorsomedial nucleus of the hypothalamus; Dzx; diazoxide; E2; estradiol; EDTA; ethylenediamine
Cardioprotective potential of annexin-A1 mimetics in myocardial infarction
Keywords: Ac2-26; Cardioprotection; Cardiomyopathy; Formyl peptide receptors; Inflammation; Ischemia-reperfusion; Aβ42; 42-amino acid beta-amyloid peptide; ABC; ATP-binding cassette; Ac2-26; N-terminal-derived annexin-A1 peptide (acetyl-AMVSEFLKQAWIENEEQEYVVQTVK
ABCC8 genetic variants and risk of diabetes mellitus
Keywords: KATP; ATP-sensitive K+; CALPN10; calpain 10; PRKACG; cAMP-dependent protein kinase catalytic subunit G; DM; diabetes mellitus; ENSA; endosulfine alpha; FOXA2; forkhead box A2; GWAS; genome-wide association studies; GDM; gestational diabetes mellitus; HVA;
D-chiro-inositol glycan stimulates insulin secretion in pancreatic β cells
Keywords: INS-2; Insulin secretion; KATP; PP2C; Islet; MIN6
Quaternary ammonium salt of U50488H, a new κ-opioid receptor agonist, protects rat heart against ischemia/reperfusion injury
Keywords: Quaternary ammonium of U50488H (PubChem CID: Q-U50488H)Quaternary ammonium of U50488H (Q-U50488H); κ-opioid receptor; KATP; Ischemia/reperfusion (I/R) injury; Myocardial infarction; Apoptosis
Hesperetin inhibits rat coronary constriction by inhibiting Ca2+ influx and enhancing voltage-gated K+ channel currents of the myocytes
Keywords: Hesperetin: PubChem CID 72281; 9,11-Dideoxy-9a,11a- methanoepoxy prostaglandin F2α (U46619): PubChem CID 5311493; S-(â)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester (Bay K 8644): PubChem CID 2303