Keywords: وقتی; Biphalin; Opioid receptors; MOR/DOR/KOR agonist; Synergistic analgesic effect; Cyclic peptides; Acm; acetamidomethyl; ACN; acetonitrile; BBB; blood brain barrier; Boc; t-butyloxycarbonyl; BOP; (benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluoro
مقالات ISI وقتی (ترجمه نشده)
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Keywords: وقتی; Sciatic nerve; TRPV1; Substance P; Manual therapy, DRG; Neuropathic pain; CCI; chronic constriction injury; DOR; δ-opioid receptor; DRG; dorsal root ganglion; KOR; κ-opioid receptor; MOR; µ-opioid receptor; NM; neural mobilization; TRPV1; transient rec
Keywords: وقتی; 3âV; third ventricle; BDNF; brain-derived neurotrophic factor; BT3; BetaTubulin-III; CA1; cornu ammonis area 1; CAq; cerebral aqueduct; CNS; central nervous system; CPE; choroid plexus epithelium; CSF; cerebrospinal fluid; DAPI; 4,6-diamidino-2-phenylin
Keywords: وقتی; Abiotic Stress; Archaea; Bacteria; Carbon Fixation; Genetic Engineering; Nitrogen Acquisition; Phosphate Acquisition; Yield; 3-PGA; 3-Phosphoglycerate; γ-ECS; γ-Glutamylcysteine synthetase; AS; Asparagine synthetase; BetA; Choline dehydrogenase; BicA; B
Keywords: وقتی; BNST; Bed nucleus of the stria terminalis; DYN; Dynorphin; KOR; Kappa-opioid receptor; MOR; mu-opioid receptor; nor-BNI; nor-binaltorphimine; Oprk1; KOR gene; Pdyn; Prodynorphin - DYN gene; USV; Ultrasonic vocalization; SA; Self administration; Alcohol de
Keywords: وقتی; Apelin; APJ receptors; Elabela; Vasodilation; Vasoconstriction; APJ; apelin receptor; ACE-2; angiotensin converting enzyme type-2; AT-1; angiotensin-1; BKCa; large conductance calcium-activated potassium; CAD; coronary artery disease; cAMP; cyclic adenosi
Keywords: وقتی; AUD; Alcohol use disorder; FDA; Food and Drug Administration; MOR; Mu opioid receptor; DOR; Delta opioid receptor; KOR; Kappa opioid receptor; NMDA; N-methyl-d-aspartate; GABA; Gaba amino butyric acid; DSM-IV; Diagnostic and statistical measurement IV; PA
Keywords: وقتی; Chronic alcohol exposure; Alcohol withdrawal; Stress; Alcohol drinking; Neuropeptides; HPA; hypothalamic-pituitary-adrenocortical; CRF; corticotropin-releasing factor; DYN; dynorphin; KOR; kappa opioid receptor; CeA; central nucleus of the amygdala; BNST;
Keywords: وقتی; Kappa opioid receptor; Serotonin; Clearance; Serotonin transporter; Phosphorylation; Trafficking; 5-HT; 5-hydroxytryptamine (serotonin); Akt X; Akt inhibitor X (10-(4â²-(N-diethylamino)butyl)-2-chlorophenoxazine); Akt; protein kinase B/Akt; BNI; nor-bina
Keywords: وقتی; BD; binge drinking; BEC; blood ethanol concentration; CNO; clozapine-n-oxide; B6; C57BL/6J inbred mice; CRF; corticotropin-releasing factor; DOR; δ-opioid receptor; DREADDS; designer receptors exclusively activated by designer drugs; DA; dopamine; DAT; d
Keywords: وقتی; ANS; autonomic nervous system; BP; blood pressure; CFA; Complete Freund's adjuvant; DRG; dorsal root ganglion; fMRI; functional magnetic resonance imaging; FSH; Follicle-stimulating hormone; GABA; gamma-Aminobutyric acid; KOR; kappa-opioid receptor; LH; L
Keywords: وقتی; Ach; acetylcholine; ACTH; adrenocorticotrophic hormone; BDNF; brain-derived neurotrophic factor; BEND; beta-endorphin; BFNA; beta-funaltrexamine; BNST; bed nucleus of the stria terminalis; Ca(2+); calcium; CaMKII; calcium/calmodulin-dependent protein kina
Keywords: وقتی; KOR (kappa opioid receptor); CRF (corticotrophin-releasing factor); GPCR (g-protein coupled receptor); GIRK (g-protein gated inwardly rectifying potassium channel); FST (forced swim test); ICSS (intracranial self-stimulation); EPM (elevated plus maze); MO
Keywords: وقتی; Drug reward; Dynorphin; Kappa opioid receptor; Paraventricular nucleus of thalamus; BNST; bed nucleus of the striaterminalis; CeA; central amygdala; Dyn-A; dynorphin-A; GIRK; G-protein-coupled inwardly rectifying potassium; GPCRs; G-protein coupled recept
Keywords: وقتی; BLa; basolateral nucleus; BLC; basolateral nuclear complex; CCK+; cholecystokinin-positive; DAB; diaminobenzidine; DOR; delta opioid receptor; KOR; kappa opioid receptor; MOR; mu opioid receptor; MOR+; MOR-positive; MOR-ir; MOR-immunoreactivity; PAG; peri
Keywords: وقتی; Fear extinction; Exposure therapy; Augmented relearning; Reconsolidation; Drug development; Cognitive enhancer; 5-HT; 5-hydroxytryptamine = serotonin; AC; adenylate cyclase; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMY; amygdala; BA;
Keywords: وقتی; Ach; acetylcholine; AchE; acetylcholine esterease; ACTH; adrenocorticotrophic hormone; ADHD; attention deficit/hyperactivity disorder; AIDS; autoimmune deficiency syndrome; AMSH; alpha-melanocyte-stimulating hormone; BAM; bovine adrenal medulla peptide; B
Keywords: وقتی; r/m HK-1; rat/mouse hemokinin-1; FAM; carboxyfluorescein; PPT; preprotachykinin; MOR; μ-opioid receptor; POMC; proopiomelanocortin; KOR; κ-opioid receptor; PDYN; prodynorphin; DOR; δ-opioid receptor; PENK; proenkephalin; GAPDH; glyceraldehyde-3-phospha
Muscarinic modulation of the Xenopus laevis tadpole spinal mechanosensory pathway
Keywords: وقتی; mAChR; Muscarinic acetylcholine receptors; nAChR; nicotinic acetylcholine receptor; dli; dorsolateral interneuron; dlc; dorsolateral commissural interneuron; dla; dorsolateral ascending interneuron; EPSP; Excitatory postsynaptic potential; IPSP; inhibitor
Can crosstalk between DOR and PARP reduce oxidative stress mediated neurodegeneration?
Keywords: وقتی; Oxidative stress (OS); Delta opioid receptor (DOR); Poly (ADP-ribose)-polymerase1 (PARP1); Neuroprotection; Attenuation; OS; Oxidative stress; DOR; Delta opioid receptor; PARP; Poly (ADP-ribose)-polymerase; AD; Alzheimer's disease; PD; Parkinson's disease
Exploring the loblolly pine (Pinus taeda L.) genome by BAC sequencing and Cot analysis
Keywords: وقتی; LP; loblolly pine; GMs; gene models; BAC; bacterial artificial chromosome; SPB; sodium phosphate buffer; Tm; melting temperature; Mmvc; monovalent cation concentration; M·s; product of nucleotide molarity and reassociation time in seconds; HR; highly rep
Novel signaling of dynorphin at κ-opioid receptor/bradykinin B2 receptor heterodimers
Keywords: وقتی; AC; adenylyl cyclase; B1R; bradykinin B1 receptor; B2R; bradykinin B2 receptor; BK; bradykinin; BRET; bioluminescence resonance energy transfer; CFP; cyan fluorescent protein; CNS; central nervous system; CRE; cAMP-response element; CREB; cAMP-response el
Involvement of the dynorphin/KOR system on the nociceptive, emotional and cognitive manifestations of joint pain in mice
Keywords: وقتی; Osteoarthritis; KOR; Dynorphin; Opioids; Anhedonia; Anxiety; Cognition;
Synergistic combinations of the dual enkephalinase inhibitor PL265 given orally with various analgesic compounds acting on different targets, in a murine model of cancer-induced bone pain
Keywords: وقتی; ACEA; arachidonyl-2â²-chloroethylamide; AEA; N-arachidonoylethanolamide, anandamide; APN; aminopeptidase N; BNI; nor-binaltorphimine; CCI; chronic constrictive injury; CYP; cyprodime; DENKI; dual enkephalinase inhibitor; DOR; delta opioid receptor; ENK;
Postoperative hyperalgesia-A clinically applicable narrative review
Keywords: وقتی; AEs; adverse events; CNS; central nervous system; COX-A; cyclooxygenase antagonists; DOR; delta opioid receptors; KOR; kappa opioid receptors; IV; intravenous(ly); LPT; long-term potentiation/potentials; MAC; monitored anesthesia care; MO; morphine; MOR;
Antagonism of the kappa opioid receptor attenuates THC-induced place aversions in adult male Sprague-Dawley rats
Keywords: وقتی; THC; norBNI; KOR; Place aversion conditioning; Rats; Dose-response;
Digital gene expression profiling of flax (Linum usitatissimum L.) stem peel identifies genes enriched in fiber-bearing phloem tissue
Keywords: وقتی; DGE; digital gene expression; DEGs; differentially expressed genes; qRT-PCR; quantitative real-time PCR; GO; the Gene Ontology database; KEGG; The Kyoto Encyclopedia of Genes and Genomes database; ESTs; expressed sequence tags; L; leaf samples; SP; stem p
Research paperEnkephalin levels and the number of neuropeptide Y-containing interneurons in the hippocampus are decreased in female cannabinoid-receptor 1 knock-out mice
Keywords: وقتی; BSA; bovine serum albumin; CA; cornu ammonis; CB1; cannabinoid 1 receptors; CCK; cholecystokinin; DG; dentate gyrus; DOR; delta-opioid receptor; DYN; dynorphin; GABA; gamma amino butyric acid; GCL; granule cell layer; IML; inner molecular layer; KOR; kapp
Research reportCB1 receptor antagonism prevents long-term hyperexcitability after head injury by regulation of dynorphin-KOR system and mGluR5 in rat hippocampus
Keywords: وقتی; CB; cannabinoid; KOR; κ opioid receptor; FPI; fluid percussion injury; PTZ; pentylenetetrazole; mGluRs; metabotropic glutamate receptors; GABA; γ-aminobutyric acid; eCBs; endocannabinoid; PTE; post-traumatic epilepsy; Post-traumatic epilepsy; Prevention
ReviewControl of arousal through neuropeptide afferents of the locus coeruleus
Keywords: وقتی; LC; locus coeruleus; CRF; corticotropin releasing factor; ORX; orexin; MCH; melanin-concentrating hormone; SS; somatostatin; NE; norepinephrine; KOR; kappa opioid receptor; MOR; mu opioid receptor; PVN; paraventricular nucleus of the hypothalamus; CNA; ce
Multitarget opioid ligands in pain relief: New players in an old game
Keywords: وقتی; Pain; MOR; DOR; KOR; Bifunctional ligands; Bivalent ligands
Morphine sulfate concomitantly decreases neuronal differentiation and opioid receptor expression in mouse embryonic stem cells
Keywords: وقتی; bFGF; basic fibroblast growth factor; DMEM; Dulbecco's Modified Eagle's Medium; DMEM-ITS; Dulbecco's Modified Eagle's Medium supplemented with insulin, transferrin, and selenium; DOR; δ-opioid receptor; EB cells; embryoid body cells; EGF; epiderm
The orexin 1 receptor modulates kappa opioid receptor function via a JNK-dependent mechanism
Keywords: وقتی; GPCR; G protein-coupled receptor; OX1R; orexin 1 receptor; KOR; kappa opioid receptor; JNK; c-Jun N-terminal kinase; cAMP; cyclic adenosine monophosphate; VTA; ventral tegmental area; CHO; Chinese hamster ovary; FLIPR; fluorescence in situ plate reader; P
Endomorphin-1 analogues (MELs) penetrate the blood-brain barrier and exhibit good analgesic effects with minimal side effects
Keywords: وقتی; Antinociception; Blood-brain barrier; Constipation; Endomorphin; Tolerance; BBB; bloodâbrain barrier; cAMP; cyclic adenosine monophosphate; CCI; chronic constriction injury; CNS; central nervous system; DOR; δ opioid receptor; EM-1; endomorphin-1; EM
Prenatal ethanol exposure alters ethanol-induced Fos immunoreactivity and dopaminergic activity in the mesocorticolimbic pathway of the adolescent brain
Keywords: وقتی; AcbC; nucleus accumbens core; AcbSh; nucleus accumbens shell; ANOVA; analysis of variance; GD; gestational day; IL; infralimbic prefrontal cortex; ir; immunoreactivity; KOR; kappa opioid receptor; NHS; normal horse serum; NM; non-manipulated during gestat
Investigation of the role of βarrestin2 in kappa opioid receptor modulation in a mouse model of pruritus
Keywords: وقتی; Pruritus; Kappa opioid receptor; Biased ligand; Mouse models of itch; U50,488H; KOR antagonist; βarr2-KO; βarrestin2 knockout; CP; chloroquine phosphate; CPA; conditioned place aversion; DMSO; dimethyl sulfoxide; 5â²-GNTI; 5â²-guanidinonaltrindole; GP
Heterodimerization of human orexin receptor 1 and kappa opioid receptor promotes protein kinase A/cAMP-response element binding protein signaling via a Gαs-mediated mechanism
Keywords: وقتی; GPCR; G-protein-coupled receptor; OX1R; orexin (hypocretin) receptor 1; KOR; kappa opioid receptor; BRET; bioluminescence resonance energy transfer; FRET; fluorescence resonance energy transfer; CREB; cAMP-response element binding protein; PKA; protein ki
Characterization of kappa opioid receptor mediated, dynorphin-stimulated [35S]GTPγS binding in mouse striatum for the evaluation of selective KOR ligands in an endogenous setting
Keywords: وقتی; Dynorphin; Kappa opioid receptor; [35S]GTPγS binding; Mouse striatum; Selectivity; Drug discovery; KOR antagonist; CTOP; D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2; DAMGO; [D-Ala2, NMe-Phe4, Gly-ol5]-enkephalin; Dyn; dynorphin; DOR; delta opioid receptor; [
Neuropathic plasticity in the opioid and non-opioid actions of dynorphin A fragments and their interactions with bradykinin B2 receptors on neuronal activity in the rat spinal cord
Keywords: وقتی; Dynorphin A; Opioid; Non-opioid; Bradykinin receptor; Neuropathy; Spinal cord; WDR; Wide dynamic range; DRG; Dorsal root ganglia; B2 receptor; Bradykinin 2 receptor; SNL; Spinal nerve ligation; CFA; Complete freund's adjuvant; KOR; Kappa opioid receptor;
Evaluation of the agonist PET radioligand [11C]GR103545 to image kappa opioid receptor in humans: Kinetic model selection, test-retest reproducibility and receptor occupancy by the antagonist PF-04455242
Keywords: وقتی; KOR; kappa opioid receptor; MOR; mu opioid receptor; DOR; delta opioid receptor; TRV; relative test-retest variability; aTRV; absolute test-retest variability; ICC; intra-class correlation coefficient; 11C-GR103545; PF-04455242; Kappa opioid receptor;
Salvinorin A regulates dopamine transporter function via a kappa opioid receptor and ERK1/2-dependent mechanism
Keywords: وقتی; Kappa opioid receptor; Dysphoric; Pro-depressant; Dopamine transporter; Serotonin transporter; Trafficking; Salvinorin A; ASP+; trans 4-(4-(dimethylamino)-styryl)-N-methylpyridinium); BNI; nor-binaltorphimine; BRET; Biolumiescence resonance energy transfe
Endogenous opiates and behavior: 2012
Keywords: وقتی; Ach; acetylcholine; ACTH; adrenocorticotrophic hormone; ANG; angiotensin; ATP; adenosine triphosphate; BAM22; bovine adrenal medulla 22; BDNF; brain-derived neurotrophic factor; BEND; beta-endorphin; BFNA; beta-funaltrexamine; BNST; bed nucleus of the str
Kappa opioid regulation of anxiety-like behavior during acute ethanol withdrawal
Keywords: وقتی; DYN; dynorphin; KOR; kappa opioid receptor; nor-BNI; norbinaltorphimine; U50,488; (trans)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclo-hexyl] benzeneacetamide; CRF; corticotropin-releasing factor; NPY; neuropeptide Y; Ethanol; Kappa opioid; Stress; W
Chromatin alterations in response to forced swimming underlie increased prodynorphin transcription
Keywords: وقتی; ANOVA; analysis of variance; BSA; bovine serum albumin; ChIP; chromatin immunoprecipitation; FST; Forced Swim Test; KOR; kappa opioid receptor; nor-BNI; norbinaltorphimine; PCR; polymerase chain reaction; pDyn; prodynorphin; stress; dynorphin; histones; C
Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein
Keywords: وقتی; 17-N-Allylamino-17-demethoxygeldanamycin (17-AAG):GABAA receptor-protein-like 1 (GABARAPL1); Glandular epithelial cell 1 (GEC1); Heat shock protein 90 (HSP90); Michigan cancer foundation-7 (MCF-7); Proteasome inhibitors; 17-AAG; 17-N-Allylamino-17-demetho
Uniform assessment and ranking of opioid Mu receptor binding constants for selected opioid drugs
Keywords: وقتی; MOR; Mu opioid receptor; DOR; delta opioid receptor; KOR; kappa opioid receptor; DAMGO; (d-Ala2, N-MePhe4, Gly-ol)-enkephalin; GPCR; G-protein coupled receptors; FDA; Food and Drug Administration; Ki; equilibrium dissociation constant for the test compoun
Opioids as facilitators of feeding: Can any food be rewarding?
Keywords: وقتی; Morphine; DAMGO; MOR; KOR; Taste aversion; Alpha-MSH; Oxytocin
Activation of peripheral delta-opioid receptors leads to anti-hyperalgesic responses in the masseter muscle of male and female rats
Keywords: وقتی; trigeminal; muscle pain; sex differences; potassium channels; Sprague-Dawley rats; AUC; area under curve; DOR; delta (δ) opioid receptor; DRG; dorsal root ganglia; KATP; ATP-sensitive potassium channels; KOR; kappa (κ) opioid receptor; MOR; mu (μ) op
GABAergic transmission modulates ethanol excitation of ventral tegmental area dopamine neurons
Keywords: وقتی; reward; mesolimbic; alcohol dependence; electrophysiology; inhibitory synaptic transmission; aCSF; artificial cerebral spinal fluid; ANOVA; analysis of variance; CeA; central amygdale; DA; dopaminergic; DOR; delta-opioid receptor; KOR; kappa-opioid recept
Up-regulation of adenylylcyclases I and II induced by long-term adaptation of rats to morphine fades away 20Â days after morphine withdrawal
Keywords: وقتی; AC; adenylyl cyclase; β-AR; β-adrenergic receptor; DADLE; [2-d-alanine, 5-d-leucine]enkephalin = Tyr-d-Ala-Gly-Phe-d-Leu; DAMGO; [2-d-alanine, 4-N-methylphenylalanine, 5-glycinol]enkephalin = Tyr-d-Ala-Gly-N-methyl-Phe-Gly-ol; DOR; δ-opioid recepto