Keywords: دیسکینزی ناشی از L-DOPA; Parkinson's disease; L-DOPA-induced dyskinesia; 6-OHDA; MPTP; Animal models; Rodents;
مقالات ISI دیسکینزی ناشی از L-DOPA (ترجمه نشده)
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Keywords: دیسکینزی ناشی از L-DOPA; 5-HIAA; 5-hydroxyindolacetic acid; 5-HT; serotonin; 6-OHDA; 6-hydroxydopamine; AIMs; Abnormal involuntary movements; ARC; activity-regulated cytoskeletal-associated protein; DA; dopamine; DOPAC; 3,4-dihydroxyphenylacetic acid; EDTA; ethylenediaminetetraac
Keywords: دیسکینزی ناشی از L-DOPA; Heterodimerization; L-DOPA-induced dyskinesia; Neurodegeneration
Modulation of CaMKIIa-GluN2B interaction in levodopa-induced dyskinesia in 6-OHDA-lesioned Parkinson's rats
Keywords: دیسکینزی ناشی از L-DOPA; CaMKIIa; GluN2B; Interactions; L-dopa-induced dyskinesia; Coimmunoprecipitation;
Selegiline increases on time without exacerbation of dyskinesia in 6-hydroxydopamine-lesioned rats displaying l-Dopa-induced wearing-off and abnormal involuntary movements
Keywords: دیسکینزی ناشی از L-DOPA; 6-OHDA; 6-hydroxydopamine; AIMs; abnormal involuntary movements; ALO; axial, forelimb and orolingual; ANOVA; analysis of variance; Arc; activity-regulated cytoskeleton-associated protein; CDS; continuous dopaminergic stimulation; COMT; catechol-O-methyltr
Behavioral and cellular dopamine D1 and D3 receptor-mediated synergy: Implications for L-DOPA-induced dyskinesia
Keywords: دیسکینزی ناشی از L-DOPA; Parkinson's disease; L-DOPA-Induced dyskinesia; Abnormal involuntary movements; D1R-D3R interactions; DA; Dopamine; DOPAC; Dihydroxyphenylacetic acid; PD; Parkinson's disease; LID; L-DOPA-Induced Dyskinesia; D1R; Dopamine D1 Receptor; D2R; Dopamine D2 Rec
The combination of the opioid glycopeptide MMP-2200 and a NMDA receptor antagonist reduced l-DOPA-induced dyskinesia and MMP-2200 by itself reduced dopamine receptor 2-like agonist-induced dyskinesia
Keywords: دیسکینزی ناشی از L-DOPA; L-DOPA-induced dyskinesia; 6-Hydroxydopamine; Opioid glycopeptide; μ-Opioid receptor (MOR); δ-Opioid receptor (DOR); NMDA receptor antagonist;
A preclinical study on the combined effects of repeated eltoprazine and preladenant treatment for alleviating L-DOPA-induced dyskinesia in Parkinson's disease
Keywords: دیسکینزی ناشی از L-DOPA; 5-HT; Serotoninergic; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NHP; Non-human primate; PD; Parkinson's disease; LID; L-DOPA-induced dyskinesia; L-DOPA; L-3,4-dihydroxyphenylalanine; Parkinson's disease; L-DOPA-induced dyskinesia; 5-HT; Adenosin
Region-specific bioconversion of dynorphin neuropeptide detected by in situ histochemistry and MALDI imaging mass spectrometry
Keywords: دیسکینزی ناشی از L-DOPA; IMS; imaging mass spectrometry; DA; dopamine; PD; Parkinson's disease; LID; L-DOPA-induced dyskinesia; NEM; N-Ethylmaleimide; DynB; dynorphin B; Neuropeptide; Dynorphin; Bioconversion; Enzyme; Enzyme inhibitor; Histochemistry; MALDI imaging mass spectro
Daily consumption of methylene blue reduces attentional deficits and dopamine reduction in a 6-OHDA model of Parkinson's disease
Keywords: دیسکینزی ناشی از L-DOPA; LID; l-dopa-induced dyskinesia; MB; methylene blue; NHS; normal horse serum; PB; phosphate buffer; PBS; phosphate-buffered saline; PD; Parkinson's disease; PFA; paraformaldehyde; SNc; substantia nigra; TH; tyrosine hydroxylase; VTA; ventral tegmental ar
Intrastriatal injection of ionomycin profoundly changes motor response to l-DOPA and its underlying molecular mechanisms
Keywords: دیسکینزی ناشی از L-DOPA; AIMs; abnormal involuntary movement scale; ANOVA; analysis of variance; CPU; striatum; CREB; cAMP response element-binding protein; DARPP32; dopamine- and c-AMP-regulated phosphoprotein of 32Â kDa; DREAM; calcium-binding protein downstream regulatory elem
Synthesis and characterization of a series of chiral alkoxymethyl morpholine analogs as dopamine receptor 4 (D4R) antagonists
Keywords: دیسکینزی ناشی از L-DOPA; Dopamine 4 receptor; Antagonist; Morpholine; L-DOPA-induced dyskinesia; Dopamine Selectivity;
The novel 5-HT1A receptor agonist, NLX-112 reduces l-DOPA-induced abnormal involuntary movements in rat: A chronic administration study with microdialysis measurements
Keywords: دیسکینزی ناشی از L-DOPA; NLX-112; Befiradol; Parkinson's disease; l-DOPA-Induced dyskinesia; 5-HT1A receptor; 5-HT1A agonist;
An evaluation of istradefylline treatment on Parkinsonian motor and cognitive deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque models
Keywords: دیسکینزی ناشی از L-DOPA; Istradefylline; KW-6002; Parkinson's disease; l-DOPA-induced dyskinesia; Cognition; MPTP; CLD; Chronic low dose; CPT; Continuous performance task; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NHP; Non-human primate; PD; Parkinson's disease; LID;
Research PaperBuspirone requires the intact nigrostriatal pathway to reduce the activity of the subthalamic nucleus via 5-HT1A receptors
Keywords: دیسکینزی ناشی از L-DOPA; 5-HT; serotonin; 6-OHDA; 6-hydroxydopamine; aCSF; artificial cerebrospinal fluid; DRN; dorsal raphe nucleus; LID; l-DOPA-induced dyskinesia; PD; Parkinson's disease; STN; subthalamic nucleus; TH; tyrosine hydroxylase; Serotonin hydrochloride (PubChem CID:
Effect of serotonin transporter blockade on L-DOPA-induced dyskinesia in animal models of Parkinson's disease
Keywords: دیسکینزی ناشی از L-DOPA; 6-OHDA; 6-hydroxydopamine; AIMs; abnormal involuntary movements; L-DOPA; L-3,4-dihydroxyphenylalanine; LID; L-DOPA-induced dyskinesia; MPTP; 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; SERT; serotonin transporter; SSRIs; selec
Loss of glutamic acid decarboxylase (Gad67) in striatal neurons expressing the Drdr1a dopamine receptor prevents l-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned mice
Keywords: دیسکینزی ناشی از L-DOPA; 6-OHDA; 6-hydroxydopamine; AIM; abnormal involuntary movements; ANOVA; Analysis of variance; Gad; glutamic acid decarboxylase; l-DOPA; levodopa; LID; l-DOPA-induced dyskinesia; GABA; 6-hydroxydopamine; levodopa; dyskinesia; striatum; striatonigral;
Derangement of Ras-Guanine Nucleotide-Releasing Factor 1 (Ras-GRF1) and Extracellular Signal-Regulated Kinase (ERK) Dependent Striatal Plasticity in L-DOPA-Induced Dyskinesia
Keywords: دیسکینزی ناشی از L-DOPA; Depotentiation; L-DOPA-induced dyskinesia; Long-term potentiation (LTP); Long-term depression (LTD); Ras-ERK signaling; Ras-GRF1; Striatum;
Modulation of l-DOPA's antiparkinsonian and dyskinetic effects by α2-noradrenergic receptors within the locus coeruleus
Keywords: دیسکینزی ناشی از L-DOPA; Locus coeruleus; l-DOPA-Induced dyskinesia; Norepinephrine; Clonidine; Atipamezole; α2-adrenoceptor;
Contribution of brain serotonin subtype 1B receptors in levodopa-induced motor complications
Keywords: دیسکینزی ناشی از L-DOPA; 5-HT1B serotonin receptor; Parkinson's disease; l-DOPA-induced dyskinesia; Human; MPTP-lesioned monkey; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AIMs; abnormal involuntary movements; DA; dopamine; DL; dorsolateral; DM; dorsomedial; GAB
Effects of prolonged neuronal nitric oxide synthase inhibition on the development and expression of l-DOPA-induced dyskinesia in 6-OHDA-lesioned rats
Keywords: دیسکینزی ناشی از L-DOPA; 6-OHDA; Dopamine; Serotonin; Parkinson's disease; l-DOPA-induced dyskinesia; Turnover; Nitric oxide; Nitric oxide synthase inhibitors;
Overexpression of GRK6 rescues l-DOPA-induced signaling abnormalities in the dopamine-depleted striatum of hemiparkinsonian rats
Keywords: دیسکینزی ناشی از L-DOPA; Parkinson's disease; l-DOPA-induced dyskinesia; GRK6; Lentivirus; ERK1/2; p38; Akt; JNK; ÎFosB;
Activity of serotonin 5-HT1A receptor 'biased agonists' in rat models of Parkinson's disease and l-DOPA-induced dyskinesia
Keywords: دیسکینزی ناشی از L-DOPA; Parkinson's disease; l-DOPA-Induced dyskinesia; l-DOPA; Dopamine, serotonin; 5-HT; Biased agonist; 5-HT1A receptor; 6-OHDA rat model of PD;
Striatal tyrosine hydroxylase-positive neurons are associated with l-DOPA-induced dyskinesia in hemiparkinsonian mice
Keywords: دیسکینزی ناشی از L-DOPA; 6-OHDA; 6-hydroxydopamine; AADC; aromatic acid decarboxylase; AIMs; abnormal involuntary movements; DA; dopamine; L-DOPA; L-3,4-dihydroxyphenylalanine; LID; L-DOPA-induced dyskinesia; MFB; medial forebrain bundle; NHS; normal horse serum; OD; optical dens
Effects of l-tryptophan on l-DOPA-induced dyskinesia in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque model of Parkinson's disease
Keywords: دیسکینزی ناشی از L-DOPA; 5-HT; 5-Hydroxytryptamine; 5-HTP; 5-Hydroxytryptophan; BBB; Blood-brain barrier; DA; Dopamine; l-DOPA; l-3,4-Dihydroxyphenylalanine; l-AADC; l-Amino acid decarboxylase; LID; l-DOPA-induced dyskinesia; MPTP; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine;
Abnormal structure-specific peptide transmission and processing in a primate model of Parkinson's disease and l-DOPA-induced dyskinesia
Keywords: دیسکینزی ناشی از L-DOPA; Parkinson's disease; Mass spectrometry; Peptides; l-DOPA-induced dyskinesia; Primate; MPTP;
(6aR)-11-Amino-N-propyl-noraporphine, a new dopamine D2 and serotonin 5-HT1A dual agonist, elicits potent antiparkinsonian action and attenuates levodopa-induced dyskinesia in a 6-OHDA-lesioned rat model of Parkinson's disease
Keywords: دیسکینزی ناشی از L-DOPA; Dopamine-D2 receptor; L-DOPA-induced dyskinesia; Parkinson disease; 5-HT1A receptor;
The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation
Keywords: دیسکینزی ناشی از L-DOPA; Graft-induced dyskinesia; L-DOPA-induced dyskinesia; Parkinson's disease; Dopamine D1 receptor; Dopamine D2 receptor; Eticlopride; SCH23390; Buspirone; Cell transplantation;
Subthalamotomy-induced changes in dopamine receptors in parkinsonian monkeys
Keywords: دیسکینزی ناشی از L-DOPA; 6-OHDA; 6-hydroxydopamine; DA; dopamine; DAT; dopamine transporter; DL; dorsolateral; DM; dorsomedial; DOPAC; 3,4-dihydroxyphenylacetic acid; GPe; globus pallidus pars externa; GPi; globus pallidus pars interna; HFS; high-frequency stimulation; HPLC; high
RGS4 is involved in the generation of abnormal involuntary movements in the unilateral 6-OHDA-lesioned rat model of Parkinson's disease
Keywords: دیسکینزی ناشی از L-DOPA; 6-OHDA; 6-hydroxydopamine; AIMs; abnormal involuntary movements; GPCR; G-protein coupled receptor; LID; l-DOPA-induced dyskinesia; PD; Parkinson's disease; PPE-B; pre-proenkephalin B; RGS; regulators of G-protein signalling; RGS4; Parkinson's disease; l-D
Angiotensin type 1 receptor blockage reduces l-dopa-induced dyskinesia in the 6-OHDA model of Parkinson's disease. Involvement of vascular endothelial growth factor and interleukin-1β
Keywords: دیسکینزی ناشی از L-DOPA; 6-OHDA; 6-hydroxydopamine; AII; angiotensin; AIMs; abnormal involuntary movements; AT1; angiotensin type 1 receptor; BBB; blood-brain barrier; DA; dopamine; DIV; days in vitro; dNTP; deoxynucleotide triphosphate; ERK; extracellular-regulated kinase; GAD
Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease
Keywords: دیسکینزی ناشی از L-DOPA; Noradrenaline; Locus coeruleus; Parkinson's disease; DBH-Saporin; Motor impairment; L-DOPA-induced dyskinesia; Staircase test
Update on the pharmacology of selective inhibitors of MAO-A and MAO-B: Focus on modulation of CNS monoamine neurotransmitter release
Keywords: دیسکینزی ناشی از L-DOPA; Enzyme active site structure; Presynaptic inhibition; Exocytotic and non-exocytotic release; Neuroprotection; Parkinson's disease; Affective disorders; MAO; monoamine oxidase; MAO-A; monoamine oxidase isoform A; MAO-B; monoamine oxidase isoform B; COMT; c
Anti-dyskinetic effect of the neuronal nitric oxide synthase inhibitor is linked to decrease of FosB/DeltaFosB expression
Keywords: دیسکینزی ناشی از L-DOPA; l-DOPA; l-3,4-dihydroxiphenylalanine; PD; Parkinson's disease; LID; l-DOPA-induced dyskinesia; SNpc; Substantia nigra pars compacta; NOS; nitric oxide synthase; l-NOARG; NG-nitro-l-Arginine; 7-NI; 7-nitroindazole; l-NAME; NG-nitro-l-Arginine-methyl esther
Behavioural pharmacologyThe dopaminergic stabilizer pridopidine decreases expression of l-DOPA-induced locomotor sensitisation in the rat unilateral 6-OHDA model
Keywords: دیسکینزی ناشی از L-DOPA; 6-OHDA; l-DOPA-induced dyskinesia; Locomotor sensitisation; Rotation; Pridopidine;
Alternative splicing of AMPA receptor subunits in the 6-OHDA-lesioned rat model of Parkinson's disease and L-DOPA-induced dyskinesia
Keywords: دیسکینزی ناشی از L-DOPA; Parkinson's disease; L-DOPA-induced dyskinesia; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; Splicing; Calcium; Animal models; Glutamate;
Modulating mGluR5 and 5-HT1A/1B receptors to treat l-DOPA-induced dyskinesia: Effects of combined treatment and possible mechanisms of action
Keywords: دیسکینزی ناشی از L-DOPA; l-DOPA-induced dyskinesia; Parkinson's disease; Metabotropic glutamate receptor 5; DA agonist; 6-OHDA rat model; 5-HT1A/1B agonists;
Synergy between l-DOPA and a novel positive allosteric modulator of metabotropic glutamate receptor 4: Implications for Parkinson's disease treatment and dyskinesia
Keywords: دیسکینزی ناشی از L-DOPA; Akinesia; Basal ganglia; Electrophysiology; l-DOPA-induced dyskinesia; Lu AF21934; Rat; Striatum;
Research ReportEffects of 5-HT1A receptor stimulation on striatal and cortical M1 pERK induction by l-DOPA and a D1 receptor agonist in a rat model of Parkinson's disease
Keywords: دیسکینزی ناشی از L-DOPA; serotonin; 5-HT; serotonin 1A receptor; 5-HT1AR; 6-hydroxydopamine; 6-OHDA; abnormal involuntary movements; AIMs; D1 receptor; D1R; dopamine; DA; ±8-OH-DPAT; DPAT; extracellular-regulated kinase; ERK; l-DOPA-induced dyskinesia; LID; primary motor cortex;
Research ReportImpact of dopamine versus serotonin cell transplantation for the development of graft-induced dyskinesia in a rat Parkinson model
Keywords: دیسکینزی ناشی از L-DOPA; 5-HT; 6-OHDA; Amphetamine-induced dyskinesia; Graft-induced dyskinesia (GID); Parkinson's disease; L-DOPA-induced dyskinesia;
Impact of L-DOPA treatment on regional cerebral blood flow and metabolism in the basal ganglia in a rat model of Parkinson's disease
Keywords: دیسکینزی ناشی از L-DOPA; AIB; [14C]-aminoisobutyric acid; AIMs; abnormal involuntary movements; BBB; blood-brain barrier; DA; dopamine; 2-DG; [14C]-2-deoxyglucose; IAP; [14C]-iodoantipyrine; KPBS-T; potassium phosphate buffered saline containing 0.25% Triton-X; LID; L-DOPA-indu
Effects of L-DOPA and STN-HFS dyskinesiogenic treatments on NR2B regulation in basal ganglia in the rat model of Parkinson's disease
Keywords: دیسکینزی ناشی از L-DOPA; 6-OHDA; 6-hydroxydopamine; AIMS; abnormal involuntary movements; DA; dopamine; EP; entopeduncular nucleus; L-DOPA; l-3,4-dihydroxyphenylalanine; LID; L-DOPA-induced dyskinesia; NMDA; N-methyl-d-aspartate; PD; Parkinson's disease; SNc; substantia nigra par
Influence of corticostriatal δ-opioid receptors on abnormal involuntary movements induced by L-DOPA in hemiparkinsonian rats
Keywords: دیسکینزی ناشی از L-DOPA; AIMs; abnormal involuntary movements; DPDPE; [d-Pen2, d-Pen5]-enkephalin; EDTA; ethylenediaminetetraacetic acid; 6-OHDA; hydroxydopamine hydrochloride, HPLC, high performance liquid chromatography; l-DOPA; l-3,4-dihydroxyphenylalanine + benserazide; LID
Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease
Keywords: دیسکینزی ناشی از L-DOPA; Graft-induced dyskinesia; L-DOPA-induced dyskinesia; Parkinson's disease; Serotonin; Dopamine D2 receptor; Cell transplantation;
Animal models of l-DOPA–induced dyskinesia: an update on the current options
Keywords: دیسکینزی ناشی از L-DOPA; l-DOPA-induced dyskinesia; 6-OHDA; MPTP; animal models; abnormal involuntary movements; Parkinson's diseaseAIMs, abnormal involuntary movements; LID, l-DOPA-induced dyskinesia; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MFB, medial forebrain bund
Positive association between striatal serotonin level and abnormal involuntary movements in chronic l-DOPA-treated hemiparkinsonian rats
Keywords: دیسکینزی ناشی از L-DOPA; Parkinson's disease; Dopamine; 5-Hydroxytryptamine; Abnormal involuntary movement score; l-DOPA-induced dyskinesia;
Role of the primary motor cortex in l-DOPA-induced dyskinesia and its modulation by 5-HT1A receptor stimulation
Keywords: دیسکینزی ناشی از L-DOPA; Primary motor cortex; Parkinson’s disease; l-DOPA-induced dyskinesia; Serotonin; c-FosDA, Dopamine; PD, Parkinson’s disease; LID, l-DOPA-induced dyskinesia; 5-HT, Serotonin; 5-HT1AR, Serotonin 1A receptor; M1, Primary motor cortex; PFC, Prefrontal cortex;
Context-driven changes in l-DOPA-induced behaviours in the 6-OHDA lesioned rat
Keywords: دیسکینزی ناشی از L-DOPA; Context-dependent conditioning; Context-specific sensitisation; l-DOPA-induced dyskinesia; Abnormal involuntary movements; Rotation
Evaluation of the D3 dopamine receptor selective agonist/partial agonist PG01042 on l-dopa dependent animal involuntary movements in rats
Keywords: دیسکینزی ناشی از L-DOPA; Parkinson's Disease; Dyskinesia; l-dopa; Dopamine receptors; D3 dopamine receptors; 6-OHDA; 6-hydroxydopamine; AIM; abnormal involuntary movement; AMG; amygdala; DMSO; dimethylsulfoxide; GIRK; G protein-regulated inward rectifying potassium channels; GP
Impact of dopamine to serotonin cell ratio in transplants on behavioral recovery and L-DOPA-induced dyskinesia
Keywords: دیسکینزی ناشی از L-DOPA; Parkinson's disease; Cell transplantation; Motor behavior; L-DOPA-induced dyskinesia; Serotonin;