Keywords: LB، بدن Lewy; Ab, antibody; α-syn, alpha-synuclein; CNS, central nervous system; ENS, enteric nervous system; GI, gastrointestinal; IBD, inflammatory bowel disease; IHC, immunohistochemistry; LB, Lewy body; LN, Lewy neurites; Mc, monoclonal; nα-syn, nitrated alpha-synu
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Keywords: LB، بدن Lewy; PD, Parkinson’s disease; DAergic, dopaminergic; SNpc, substantia nigra pars compacta; DA, dopamine; LB, lewy body; α-syn, alpha synuclein; L-DOPA, levodopa; MAO, monoamine oxidase; CNS, central nervous system; DDS, drug delivery systems; MPs, microparticl
Sensitive analysis of α-synuclein by nonlinear laser wave mixing coupled with capillary electrophoresis
Keywords: LB، بدن Lewy; Ultrasensitive nonlinear spectroscopy; Electrophoresis; α-Synuclein; Parkinson's diseasePD, Parkinson's disease; LB, Lewy body; SNARE, soluble N-ethylmaleimide sensitive factor attachment protein receptor; CSF, cerebrospinal fluid; ELISA, enzyme-linked im
Chronic mild stress accelerates the progression of Parkinson's disease in A53T α-synuclein transgenic mice
Keywords: LB، بدن Lewy; PD, Parkinson's disease; CMS, chronic mild stress; LB, Lewy body; 6-OHDA, 6-hydroxy-dopamine; DA, dopamine; CORT, corticosterone; TH, tyrosine hydroxylase; Iba-1, ionized calcium-binding adaptor molecule 1; SNpc, substantia nigra pars compacta; DOPAC, dih
Splicing variants of porcine synphilin-1
Keywords: LB، بدن Lewy; ORF, open reading frame; LB, Lewy body; SNCAIP, α-synuclein interacting proteinα-Synuclein; Lewy body; Parkinson's disease; Pig; Synphilin-1
Axon degeneration in Parkinson's disease
Keywords: LB، بدن Lewy; [3H]TBZOH, tritiated α-dihydrotetrabenazine; 6-OHDA, 6-hydroxydopamine; AAV, adeno-associated virus; AD, Alzheimer's disease; AVs, autophagic vacuoles; DLB, dementia with Lewy Bodies; ILB, incidental Lewy bodies; LB, Lewy body; LRRK2, leucine rich repeat
Parkin Co-Regulated Gene is involved in aggresome formation and autophagy in response to proteasomal impairment
Keywords: LB، بدن Lewy; 3-MA, 3-methyladenine; AV, autophagic vesicle; BSA, bovine serum albumin; ER, endoplasmic reticulum; FBS, foetal bovine serum; LB, Lewy body; LC3, light chain 3; MT, microtubule; MTOC, microtubule organising centre; PACRG, Parkin Co-Regulated Gene; PD, Pa
Genetically engineered mouse models of Parkinson's disease
Keywords: LB، بدن Lewy; MPTP, 1-methyl 4-phenyl 1,2,3,6-tetrahydropyridine; MPP+, 1-methyl-4-phenylpyridinium; 6-OHDA, 6-hydroxydopamine; COMT, catechol-O-methyltransferase; DA, dopamine; DAT, dopamine transporter; L-DOPA, levodopa; LB, Lewy body; LPS, lipopolysaccharride; MAOB,
Conserved C-Terminal Charge Exerts a Profound Influence on the Aggregation Rate of α-Synuclein
Keywords: LB، بدن Lewy; PD, Parkinson's disease; LB, Lewy body; α-syn, α-synucleinParkinson's disease; α-synuclein; aggregation; posttranslational modification; linear growth theory
The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease
Keywords: LB، بدن Lewy; Parkinson's disease; pacemaking; calcium; endoplasmic reticulum; mitochondrial oxidant stress; l-type channelsDA, dopaminergic; DHP, dihydropyridine; ER, endoplasmic reticulum; LB, Lewy body; LC, locus ceruleus; mito-roGFP, mitochondrially-targeted redox-
Leucine-rich repeat kinase 2 induces α-synuclein expression via the extracellular signal-regulated kinase pathway
Keywords: LB، بدن Lewy; ERK, extracellular signal-regulated kinase; JNK, c-Jun N-terminal kinase; LB, Lewy body; LRRK2, leucine-rich repeat kinase 2; MAPK, mitogen-activated protein kinase; MEK, MAPK/ERK kinase; PD, Parkinson's disease; SNCA, α-synucleinLRRK2; Mitogen-activated
Proteomics in human Parkinson's disease research
Keywords: LB، بدن Lewy; ALS, amyotrophic lateral sclerosis; α-SYN, α-synuclein; AD, Alzheimer's disease; CNS, central nervous system; CSF, cerebrospinal fluid; DA, dopamine; DUB, deubiquinating enzyme; 2-DE, two-dimensional electrophoresis; HE, hematoxylin–eosin; LB, Lewy body;
N-terminal region of α-synuclein is essential for the fatty acid-induced oligomerization of the molecules
Keywords: LB، بدن Lewy; PD, Parkinson’s disease; αS, alpha-synuclein; LB, Lewy body; LN, Lewy neurite; FA, fatty acid; PUFA, polyunsaturated fatty acid; FABP, fatty acid-binding protein; OA, Oleic acid; ALA, α-linolenic acid; GRK, G protein-coupled receptor kinase; NAC, non-amyl
Regional and cellular localisation of Parkin Co-Regulated Gene in developing and adult mouse brain
Keywords: LB، بدن Lewy; EO-PD, early-onset Parkinson's disease; GFAP, glial fibrillary acidic protein; Gapdh, Glyceraldehyde-3-phosphate dehydrogenase; 12N, hypoglossal nucleus; kDa, kilodalton; LB, Lewy body; MdV, medullar reticular nucleus; PACRG, Parkin Co-Regulated Gene; PRK
Selective loss of nigral dopamine neurons induced by overexpression of truncated human α-synuclein in mice
Keywords: LB، بدن Lewy; DA, dopamine; H&E, hematoxylin and eosin; LB, Lewy body; PD, Parkinson's disease; SNc, substantia nigra pars compacta; Tg, transgenic; TH, tyrosine hydroxylase; VTA, ventral tegmental areaParkinson's disease; Animal model; α-Synuclein; Transgenic mouse; T
Ultra-high field NMR studies of antibody binding and site-specific phosphorylation of α-synuclein
Keywords: LB، بدن Lewy; CK2, casein kinase 2; LB, Lewy body; NMR, nuclear magnetic resonanceUltra-high field NMR spectroscopy; Intrinsically disordered protein; α-Synuclein; Phosphorylation; Antibody; Epitope
Parkin Co-regulated Gene (PACRG) is regulated by the ubiquitin–proteasomal system and is present in the pathological features of parkinsonian diseases
Keywords: LB، بدن Lewy; bp, base pairs; BSA, bovine serum albumin; EO-PD, early-onset Parkinson's disease; FBS, fetal bovine serum; GFAP, glial fibrillary acidic protein; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; kDa, kilodalton; LB, Lewy body; LC, locus coeruleus; MSA, m
α-Synuclein enhances dopamine D2 receptor signaling
Keywords: LB، بدن Lewy; CHO, Chinese hamster ovary; CRE, cAMP-responsive element; D2R, dopamine D2 receptor; LB, Lewy body; MAPK, mitogen-activated protein kinase; PD, Parkinson's disease; RIA, radioimmunoassay; SN, substantia nigraα-Synuclein; Dopamine; Dopamine D2 receptor; cA
Interaction of TPPP/p25 protein with glyceraldehyde-3-phosphate dehydrogenase and their co-localization in Lewy bodies
Keywords: LB، بدن Lewy; DAPI, 4′,6-diamidino-2-phenylindole; DHB, 2,5-dihydroxybenzoic acid; DTE, 1,4-dithioerythritol; DTT, 1,4-dithiothreitol; FCS, fetal calf serum; GAPDH (EC 1.2.1.12), glyceraldehyde-3-phosphate dehydrogenase; IAM, iodoacetamide; LB, Lewy body; MALDI-TOF, ma
A Novel Mechanism of Interaction between α-Synuclein and Biological Membranes
Keywords: LB، بدن Lewy; α-syn, α-synuclein; LB, Lewy body; PD, Parkinson’s disease; DSG, disuccinimidyl glutarate; DSP, dithiobis [succinimidylpropionate]; PK, proteinase K; SUV, small unilamellar vesicles; PA; PC; PGParkinson’s disease; synuclein; membrane; chemical crosslinkin