Keywords: LC، locus coeruleus; CCI, Chronic Constriction Injury; ED50, Effective Dose 50; EZM, Elevated Zero Maze test; i.p., Intraperitoneal; i.v., Intravenous; LC, Locus Coeruleus; NAT, Noradrenaline Transporter; pCREB, Phospho-cAMP Response Element-Binding protein; STZ, Streptozotoc
مقالات ISI LC، locus coeruleus (ترجمه نشده)
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Keywords: LC، locus coeruleus; BSA, bovine serum albumin; EGFP, enhanced green fluorescent protein; GiA, gigantocellular nucleus pars α; IML, intermediolateral cell column; LC, locus coeruleus; LH, lateral hypothalamus; NGS, normal goat serum; NTS, nucleus tractus solitarius; PAG, peri
Keywords: LC، locus coeruleus; LC, locus coeruleus; NSIA, noxious stimulation-induced analgesia; mGluRs, metabotropic glutamate receptors; GLT-1, glutamate transporter-1; siRNA, small interfering RNALocus coeruleus; Astrocytes; Glutamate transporter-1; Endogenous analgesia; Small inter
Keywords: LC، locus coeruleus; ACC, anterior cingulate cortex; TMN, tuberomammillary nucleus; DH, dorsal hippocampus; DG, dentate gyrus; PSC, primary somatosensory cortex; PAG, periaqueductal gray; RN, raphe nucleus; LC, locus coeruleus; CABA, gama-amino butyric acid; CCK, cholecystoki
Keywords: LC، locus coeruleus; 5-HT, serotonin; ACh, acetylcholine; GABA, gamma-aminobutyric acid; HA, histamine; IN, interneuron; LC, locus coeruleus; LH, lateral hypothalamus; PFC, prefrontal cortex; SCN, suprachiasmatic nucleus; SERT, serotonin transporter; TMN, tuberomammillary nuc
Keywords: LC، locus coeruleus; DR, dorsal raphe; DMH, dorsomedial hypothalamus; GPCR, G protein coupled receptor; GABA, gamma amino butyric acid; LDT, laterodorsal tegmental nucleus; LC, locus coeruleus; LPC, lysophosphatydylcholine; NMDA, N-methyl-d-aspartate; NSCC, non-selective cati
The μ1-opioid receptor and 5-HT2A- and 5HT2C-serotonergic receptors of the locus coeruleus are critical in elaborating hypoalgesia induced by tonic and tonic–clonic seizures
Keywords: LC، locus coeruleus; DMSO, dimethyl sulfoxide; DRN, dorsal raphe nucleus; LC, locus coeruleus; PAG, periaqueductal gray matter; PTZ, pentylenetetrazole; TFLs, tail-flick latenciespost-ictal antinociception; GABA-A receptor; locus coeruleus; μ1-opiod receptors; 5-HT2A- and 5-H
Pedunculopontine arousal system physiology – Deep brain stimulation (DBS)
Keywords: LC، locus coeruleus; DBS, deep brain stimulation; EEG, electroencephalogram; LC, locus coeruleus; PD, Parkinson׳s disease; PGO, ponto-geniculo-occipital; PPN, pedunculopontine nucleus; REM, rapid eye movement; RAS, reticular activating system; SN, substantia nigra; STN, subth
β1-and β2-adrenoceptors in hippocampal CA3 region are required for long-term memory consolidation in rats
Keywords: LC، locus coeruleus; AC, Adenyl cyclase; AR, Adrenoceptor; BSA, Bovine serum albumin; CA1, Cornu ammonis 1; CA3, Cornu ammonis 3; GPCR, G Protein-coupled receptor; LC, Locus coeruleus; NE, Norepinephrine; PB, Phosphate buffer; PBS, Phosphate-buffered saline; PKA, cAMP-depende
Characterization of nociceptive response to chemical, mechanical, and thermal stimuli in adolescent rats with neonatal dopamine depletion
Keywords: LC، locus coeruleus; 6-OHDA, 6-hydroxydopamine; ADHD, attention-deficit hyperactivity disorder; ANOVA, analysis of variance; Fos-ir, c-Fos-immunoreactivity; LC, locus coeruleus; MAP, methamphetamine; SN, substantia nigra; TH, tyrosine hydroxylase; VTA, ventral tegmental arean
Mouse strain and brain region-specific expression of the glutaminyl cyclases QC and isoQC
Keywords: LC، locus coeruleus; AD, Alzheimer's disease; APP, amyloid precursor protein; CCL2, chemokine (C-C motif) ligand 2; EWN, Edinger–Westphal nucleus; LC, locus coeruleus; MCP-1, monocyte chemoattractant protein-1; PB, phosphate buffer; PBS, phosphate-buffered saline; QC, glutami
Functional role of Barrington’s nucleus in the micturition reflex: Relevance in the surgical treatment of Parkinson’s disease
Keywords: LC، locus coeruleus; BN, Barrington’s nucleus; CRF, corticotropin-releasing factor; DBS, deep brain stimulation; GPe, external globus pallidus; GPi, internal globus pallidus; LC, locus coeruleus; LUT, lower urinary tract; PAG, periaqueductal gray matter; PD, Parkinson’s disea
Alpha-synuclein interferes with cAMP/PKA-dependent upregulation of dopamine β-hydroxylase and is associated with abnormal adaptive responses to immobilization stress
Keywords: LC، locus coeruleus; PD, Parkinson's disease; NErgic, norepinephrinergic; NE, norepinephrine; DBH, dopamine β-hydroxylase; LC, locus coeruleus; TH, tyrosine hydroxylase; cAMP, cyclic AMP; CRE, cAMP response element; α-SYN, alpha-synuclein; PBS, phosphate-buffered saline; ECL,
Differential regulation of CDK5 and c-Fos expression by morphine in the brain of Lewis and Fischer 344 rat strains
Keywords: LC، locus coeruleus; AP-1, activator protein-1; CDK5, cyclin-dependent kinase 5; DARPP-32, dopamine- and cAMP-regulated phosphoprotein, Mr 32 kDa; DPX, distyrene plasticizer xylene; F344, Fischer 344; LC, locus coeruleus; NAC, nucleus accumbens; NTS, nucleus tractus solitariu
Neuroanatomical distribution of μ-opioid receptor mRNA and binding in monogamous prairie voles (Microtus ochrogaster) and non-monogamous meadow voles (Microtus pennsylvanicus)
Keywords: LC، locus coeruleus; AChE, acetylcholinesterase; CP, caudate-putamen; CRF, corticotropin-releasing factor; CTAP, d-Phe-Cys-Tyr-d-Trp-Arg-Thr-Pen-Thr-NH2; KOR, κ-opioid receptor; LC, locus coeruleus; LS, lateral septal nucleus; MnR, median raphe; MOR, μ-opioid receptor; NAcsh,
Translational reciprocity: Bridging the gap between preclinical studies and clinical treatment of stress effects on the adolescent brain
Keywords: LC، locus coeruleus; ACTH, adrenocorticotropic hormone; BPD, borderline personality disorder; CRF, corticotropin-releasing factor; DHEA, dehydroepiandrosterone; GR, glucocorticoid receptor; HPA, hypothalamic–pituitary–adrenal; LC, locus coeruleus; MDD, major depressive disord
Immunohistochemical evidence for synaptic release of GABA from melanin-concentrating hormone containing varicosities in the locus coeruleus
Keywords: LC، locus coeruleus; Cy, cyanine; GAD, glutamic acid decarboxylase; Geph, gephyrin; LC, locus coeruleus; LDCV, large dense core vesicles; MCH, melanin-concentrating hormone; NA, noradrenaline; Orx, orexin; PS, paradoxical sleep; REM, rapid eye movement; SSV, small synaptic ve
Rat vagus nerve stimulation model of seizure suppression: nNOS and ΔFos B changes in the brainstem
Keywords: LC، locus coeruleus; AMB, nucleus ambiguus; DMV, dorsal motor nucleus of the vagus nerve; LC, locus coeruleus; nNOS, neuronal nitric oxide synthase; NTS, nucleus of the solitary tract; PBN, parabrachial nucleus; TBS, Tris-buffered saline; TBS-T, Tris-buffered saline containin
Arousal effects of orexin A on acute alcohol intoxication-induced coma in rats
Keywords: LC، locus coeruleus; Orexins; Arousal; Alcohol intoxication; Coma; Prefrontal cortex; Histamine; Serotonin; NoradrenalinePFC, prefrontal cortex; LC, locus coeruleus; TMN, tuberomammillary nuclei; DR, dorsal raphe; CSF, cerebrospinal fluid; EEG, electroencephalogram; i.c.v., i
The amnesic effect of intra-central amygdala administration of a cannabinoid CB1 receptor agonist, WIN55,212-2, is mediated by a beta-1 noradrenergic system in rat
Keywords: LC، locus coeruleus; BLA, basolateral amygdala; CeA, central amygdala; IA, inhibitory avoidance; LC, locus coeruleus; mPFC, medial prefrontal cortex; NE, norepinephrine; VTA, ventral tegmental areacannabinoid receptor; amnesia; isoprenaline; atenolol; central amygdala; rat
Cannabinoid modulation of noradrenergic circuits: Implications for psychiatric disorders
Keywords: LC، locus coeruleus; AR, adrenergic receptor; CB1r, cannabinoid type 1 receptor; ∆9-THC, ∆9-tetrahydrohydrocannabinol; FAAH, fatty acid amide hydrolase; LC, locus coeruleus; MAO, monoamine oxidase; NE, norepinephrine; NET, norepinephrine transporter; Acb, nucleus accumbens; N
Loss of spinal motor neurons and alteration of alpha-synuclein immunostaining in MPTP induced Parkinsonism in mice
Keywords: LC، locus coeruleus; α-syn, alpha-synuclein; ALS, Amyotrophic Lateral Sclerosis; CNS, central nervous system; DA, dopamine; DAT, dopamine transporter; GFAP, glial fibrillar acidic protein; H&E, hematoxilin and eosin; LC, locus coeruleus; MAO-B, monoammino-oxidase type B; MPP+
Automated gait analysis in bilateral Parkinsonian rats and the role of l-DOPA therapy
Keywords: LC، locus coeruleus; DA, dopamine; K–S, Kolmogorov–Smirnov (normality test); l-DOPA, levodopa, 3,4-dihydroxyphenyl-l-alanine; LC, locus coeruleus; mfb, medial forebrain bundle; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridin; NA, noradrenalin; 6-OHDA, 6-hydroxydopamine; PD,
Dorsal horn antinociception mediated by the paraventricular hypothalamic nucleus and locus coeruleous: A comparative study
Keywords: LC، locus coeruleus; LC, locus coeruleus; PVN, paraventricular hypothalamic nucleus; PAG, periaqueductal gray; WDR, wide dynamic range; YOH, yohimbinePain; Antinociception; Spinal cord; Noradrenaline; Oxytocin
Opioids inhibit visceral afferent activation of catecholamine neurons in the solitary tract nucleus
Keywords: LC، locus coeruleus; AP, action potential; CA, catecholamine; EGTA, ethylene glycol tetraacetic acid; HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; LC, Locus Coeruleus; Met-Enk, Met-enkephalin; MOP-Rs, mu opioid receptors; NTS, solitary tract nucleus; ST-EPSCs, s
Interaction between the carbon monoxide and nitric oxide pathways in the locus coeruleus during fever
Keywords: LC، locus coeruleus; bilirubin; heme oxygenase; nitrite/nitrate; nitric oxide synthase; thermoregulation; lipopolysaccharidecGMP, cyclic guanosine 3′,5′-monophosphate; CO, carbon monoxide; COX, cyclooxygenase; CSF, cerebrospinal fluid; HO, heme oxygenase; LC, locus coeruleus;
Neurobiological studies of fatigue
Keywords: LC، locus coeruleus; BF, basal forebrain; BDNF, brain-derived neurotrophic factor; DMH, dorsomedial hypothalamus; IGL, intergeniculate leaflet; LH, lateral hypothalamus; LDT, laterodorsal tegmentum; LPS, lipopolysaccaride; LC, locus coeruleus; MnPO, median preoptic area; MAPK
Activation of inactivation process initiates rapid eye movement sleep
Keywords: LC، locus coeruleus; α, alpha; ACh, acetylcholine; CRF, caudal brain stem reticular formation; EEG, electroencephalogram; EMG, electromyogram; EOG, electrooculogram; FTG, gigantocellular tegmental field; GABA, gamma amino butyric acid; LC, locus coeruleus; LDT, laterodorsal t
Altered circadian profiles in attention-deficit/hyperactivity disorder: An integrative review and theoretical framework for future studies
Keywords: LC، locus coeruleus; APA, American Psychiatric Association; ADHD, attention-deficit hyperactivity disorder; SCN, suprachiasmatic nucleus; CLOCK gene, circadian locomotor output cycles kaput gene; LC, locus coeruleus; MSLT, multiple sleep latency test; PSG, polysomnography; OD
Impairment of the tyrosine hydroxylase neuronal network in the orbitofrontal cortex of a genetically modified mouse model of schizophrenia
Keywords: LC، locus coeruleus; Animal model; Immunohistochemistry; Orbitofrontal cortex; Schizophrenia; 14-3-3 EpsilonKO, knockout; TH, tyrosine hydroxylase; VTA, ventral tegmental area; LC, locus coeruleus
Taltirelin, a thyrotropin-releasing hormone analog, alleviates mechanical allodynia through activation of descending monoaminergic neurons in persistent inflammatory pain
Keywords: LC، locus coeruleus; CFA, complete Freund's adjuvant; CMC, carboxymethylcellulose; CNS, central nervous system; LC, locus coeruleus; 6-OHDA, 6-hydroxydopamine; PAG, periaqueductal gray; PCPA, dl-p-chlorophenylalanine; RVM, rostral ventromedial medulla; TRH, thyrotropin-releas
Differential effects of inescapable stress on locus coeruleus GRK3, alpha2-adrenoceptor and CRF1 receptor levels in learned helpless and non-helpless rats: A potential link to stress resilience
Keywords: LC، locus coeruleus; AR, adrenoceptor; CRF1, corticotropin-releasing factor 1 receptor; LH, learned helpless; NH, non-helpless; TC, tested control; LC, locus coeruleus; GPCR, G protein-coupled receptor; GRK, G protein-coupled receptor kinase; TH, tyrosine hydroxylaseLearned h
Animal models for vagus nerve stimulation in epilepsy
Keywords: LC، locus coeruleus; 3-MPA, mercaptopropionic acid; EEG, electro encephalogram; GAERS, genetic absence epilepsy rats from Strasbourg; LC, locus coeruleus; NE, norepinephrine; NTS, nucleus tractus solitarius; PTZ, pentylenetetrazole; VNS, vagus nerve stimulationVagus nerve sti
Sex-specific influence of exposure to bisphenol-A between adolescence and young adulthood on mouse behaviors
Keywords: LC، locus coeruleus; Bisphenol-A; Behavior; Learning and memoryBPA, bisphenol-A; CNS, central nervous system; EPA, Environmental Protection Agengy; LC, locus coeruleus; PND, postnatal day; Ovx, ovariectomized; LTP, long-term potentiation
Progress and challenges in the study of α6-containing nicotinic acetylcholine receptors
Keywords: LC، locus coeruleus; α-Ctx, alpha-conotoxin; CNS, central nervous system; GoF, gain-of-function; KO, knock-out; LC, locus coeruleus; MPTP, 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine; nAChRs, nicotinic acetylcholine receptors; PD, Parkinson's disease; PET, positron emission
Adaptation to potential threat: The evolution, neurobiology, and psychopathology of the security motivation system
Keywords: LC، locus coeruleus; AM, amygdala; BNST, bed nucleus of the stria terminalis; CRH, corticotropin-releasing hormone; GC, glucocorticoids; HPC, hippocampus; LC, locus coeruleus; MOPFC, medial prefrontal cortex and orbital prefrontal cortex; PVN, paraventricular nucleusPotential
Differential effects of background noise of various intensities on neuronal activation associated with arousal and stress response in a maze task
Keywords: LC، locus coeruleus; BF, basal forebrain; BGN, background noise; BLA, basolateral amygdala; CeA, central nucleus of amygdala; ChAT, choline acetyltransferase; LC, locus coeruleus; LDT, laterodorsal tegmental nucleus; MS/DS, medial septum/vertical limb of the diagonal band; MT
c-Fos induction by a 14 T magnetic field in visceral and vestibular relays of the female rat brainstem is modulated by estradiol
Keywords: LC، locus coeruleus; ANOVA, analysis of variance; AP, area postrema; BSA, bovine serum albumin; cc, central canal; CTA, conditioned taste aversion; ER, estrogen receptor; IV, fourth ventricle; LC, locus coeruleus; lPBN, lateral parabrachial nucleus; MeV, medial vestibular nuc
Noradrenergic lesion of the locus coeruleus increases apomorphine-induced circling behavior and the firing activity of substantia nigra pars reticulata neurons in a rat model of Parkinson's disease
Keywords: LC، locus coeruleus; DA, dopamine; DSP-4, N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine; ISI, interspike interval; ISIH, interspike interval histogram; LC, locus coeruleus; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NA, noradrenalin; PBS, phosphate buffered saline; PD
Selective noradrenergic vulnerability in alpha-synuclein transgenic mice
Keywords: LC، locus coeruleus; PD, Parkinson's disease; DA, dopamine; DOPAC, 3,4 dihydroxyphenylacetic acid; HVA, homovanillic acid; NE, noradrenaline; LC, locus coeruleus; SN, substantia nigra; str, striatum; Cx, cortex; OB, olfactory bulb; Sp.C, spinal cord; mesen, mesenechaphalon; T
Hypocretin/orexin in arousal and stress
Keywords: LC، locus coeruleus; ACTH, adrenocorticotropin hormone; CRF, corticotropin-releasing factor; DA, dopamine; HCRT, hypocretin/orexin; HPA, hypothalamo–pituitary–adrenal; ICV, intracerebroventricular; LC, locus coeruleus; LH, lateral hypothalamus; MSA, medial septal area; MPOA,
MPTP-induced parkinsonism extends to a subclass of TH-positive neurons in the gut
Keywords: LC، locus coeruleus; Parkinson's disease; Gut; MPTP; Mouse; DopaminePD, Parkinson's disease; DA, dopamine; LC, locus coeruleus; NE, norepinephrine; GI, gastrointestinal; ENS, enteric nervous system; 6-OHDA, 6-hydroxydopamine; MP, myenteric plexus; TH, tyrosine hydroxylase; SD
Studies on the hippocampal formation: From basic development to clinical applications: Studies on schizophrenia
Keywords: LC، locus coeruleus; EEG, electroencephalogram; GABA, gamma aminobutyric acid; CA1, cornu ammonis 1 of hippocampus; CA2, cornu ammonis 2 of hippocampus; CA3, cornu ammonis 3 of hippocampus; LC, locus coeruleus; LOD, logarithmic odds; NMDA, N-methyl-d-aspartic acid; S, septal
Characterization of cannabinoid-1 receptors in the locus coeruleus: Relationship with mu-opioid receptors
Keywords: LC، locus coeruleus; CB1r, cannabinoid receptor type 1; CB1r−/−, CB1r knock out; EM, electron microscopy; FITC, fluorescein isothiocyanate; -ir, immunoreactivity; i.p., intraperitoneal; LC, locus coeruleus; MOR, mu-opioid receptor; NE, norepinephrine; PGi, nucleus paragiganto
Autism, fever, epigenetics and the locus coeruleus
Keywords: LC، locus coeruleus; ASD, autism spectrum disorders; CpG, cytosine dinucleotide; CRH, corticotropin-releasing hormone; LC, locus coeruleus; LC-NA, locus coeruleus-noradrenergic system; LPS, lipopolysaccharide; NA, noradrenalineGene–environmental interaction; Prenatal stressor
Effect of reversible inactivation of locus ceruleus on spatial reference and working memory
Keywords: LC، locus coeruleus; working memory; reference memory; Morris water maze; reversible inactivation; LC; noradrenergic systemAch, acetylcholine; DNB, dorsal noradrenergic bundle; LC, locus coeruleus; MSA, medial septal area; MWM, Morris water maze; NE, norepinephrine; PH, prepo
Dissecting natural sensory plasticity: Hormones and experience in a maternal context
Keywords: LC، locus coeruleus; A1, primary auditory field; AAF, anterior auditory field; AC, auditory cortex; AII, secondary auditory field; Dbh, dopamine beta-hydroxylase; DR, dorsal raphe nuclei; ER, estrogen receptor; LC, locus coeruleus; MU, multiunit; NB, nucleus basalis; TH, tyro
Stress-induced activity in the locus coeruleus is not sensitive to stressor controllability
Keywords: LC، locus coeruleus; LC, locus coeruleus; NE, norepinephrine; TH, tyrosine hydroxylase; ABC, avidin–biotin–horseradish peroxidase complex; PBS, phosphate-buffered saline; DAB, 3,3′-diaminobenzidine tetrahydrochloride; ANOVA, analysis of variance; HC, homecage control; ES, esc
The firing activity of pyramidal neurons in medial prefrontal cortex and their response to 5-hydroxytryptamine-1A receptor stimulation in a rat model of Parkinson's disease
Keywords: LC، locus coeruleus; medial prefrontal cortex; 5-hydroxytryptamine; 5-HT1A receptors; Parkinson's disease; electrophysiologyDA, dopamine; DRN, dorsal raphe nucleus; ISI, interspike interval; ISIH, interspike interval histogram; LC, locus coeruleus; mPFC, medial prefrontal cor
Electrophysiological characterization of the effects of asenapine at 5-HT1A, 5-HT2A, α2-adrenergic and D2 receptors in the rat brain
Keywords: LC، locus coeruleus; 5-HT, 5-hydroxytryptamine (serotonin); DRN, dorsal raphe nucleus; LC, locus coeruleus; NE, norepinephrine; SSRI, selective serotonin reuptake inhibitor; VTA, ventral tegmental area; 8-OH-DPAT, 8-hydroxy-2-(di-n-propylamino) tetralin; WAY100635, N-{2-[4(2-