Keywords: لپه; High internal phase emulsions; Medium internal phase emulsions; PolyMIPEs; PolyHIPEs; Hydrophilic porous polymers; IP; Internal phase; HIPE; High internal phase emulsion; MIPE; Medium internal phase emulsion; LIPE; Low internal phase emulsion; w.r.t; With
مقالات ISI لپه (ترجمه نشده)
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Keywords: لپه; Dihydrocapsiate; HFD; Obesity; Glucose intolerance; Hepatic steatosis; ACOX1; Acyl-CoA oxidase 1; ADIPO; adiponectin; AIN; American Institute of Nutrition; ANOVA; 1-way analysis of variance; BAT; brown adipose tissue; BMI; body mass index; C/EBPβ; CCAAT/
Keywords: لپه; Digestibility; LIPE; Sorghum silage; Weanling horse;
Keywords: لپه; Glycosaminoglycans; Weight loss; Fat loss; White adipose tissue; Oxidative metabolism; B2m; beta-2 microglobulin; BAT; brown adipose tissue; CCK; cholecystokinin; Cox5a; cytochrome c oxidase subunit Va; Cpt1a; carnitine palmitoyltransferase 1a (liver isof
Keywords: لپه; Muscle fat; Pig; Adipogenesis; Meat quality; Fat genes; FASN; LIPE; SCD; LPL; Gene expression; Protein; Lipid metabolism;
Keywords: لپه; Bmp4; bone morphogenetic protein 4; EGCG; (-)-epigallocatechin-3-gallate; Ex; voluntary exercise; GTE; decaffeinated green tea extract; HF; high fat diet; Lipe; hormone sensitive lipase; LF; low fat; mt-Co3; cytochrome C oxidase subunit III; mt-Cytb; cyto
Long-term inhibition of PDE5 ameliorates aging-induced changes in rat testis
Keywords: لپه; Actb/ACTB; gene/protein for β-actin; AKT; protein for protein kinase B (AKT/PRKGB); BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; Cyp11a1; gene for cytochrome P450 side chain cleavage enzyme; Cyp17
Part A: Temporal and dose-dependent transcriptional responses in the liver of fathead minnows following short term exposure to the polycyclic aromatic hydrocarbon phenanthrene
Keywords: لپه; SREBF1; sterol regulatory element binding transcription factor 1; FASN; fatty acid synthase; HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12; ACACA; acetyl-CoA carboxylase alpha; CYB5A; cytochrome b5 type A (microsomal); SLC27A4; solute carrier family
Novel indanone derivatives as MAO B/H3R dual-targeting ligands for treatment of Parkinson's disease
Keywords: لپه; Multi-targeting; Neurodegenerative diseases; Histamine H3 receptor antagonist; Monoamine oxidase inhibitor; Neurotransmitter dysregulation; Parkinson's disease; AChE; acetylcholinesterase; anal. calc.; elementary analysis calculated; BuChE; butyrylcholine
Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes
Keywords: لپه; ADME; absorption, distribution, metabolism and excretion; Clint; intrinsic clearance; Clp; plasma clearance; Clu; unbound clearance; DCM; dichloromethane; DHEP; dog hepatocytes; DLM; dog liver microsomes; DMAc; dimethylacetamide; DMF; dimethylformamide; D
Diverse amide analogs of sulindac for cancer treatment and prevention
Keywords: لپه; NSAID; non-steroidal anti-inflammatory drug; COX; cyclooxygenase; SSA; sulindac sulfide amide; SAR; structure-activity relationship; AA; amino acid; ALL; acute lymphoblastic leukemia; CPC; choroid plexus carcinoma; TPSA; topological polar surface area; Li
Optimization of amide-based EP3 receptor antagonists
Keywords: لپه; EP3 receptor; PGE2; GPCR; LipE; Metabolites; P-gp; Indazole;
Translocator protein ligands based on N-methyl-(quinolin-4-yl)oxypropanamides with properties suitable for PET radioligand development
Keywords: لپه; Translocator protein; PET; Carbon-11; Ligand; Binding affinity; Lipophilic efficiency; DIPEA; diisopropylethylamine; DMF; N,N-dimethylformamide; DMSO; dimethylsulfoxide; HFIP; hexafluoroisopropyl alcohol; HRMS-ESI; high resolution mass spectrometry electr
2-Acylamino-5-nitro-1,3-thiazoles: Preparation and in vitro bioevaluation against four neglected protozoan parasites
Keywords: لپه; Neglected diseases; Nitazoxanide; 5-Nitrothiazole; Giardia; LiPE;
Kinase domain inhibition of leucine rich repeat kinase 2 (LRRK2) using a [1,2,4]triazolo[4,3-b]pyridazine scaffold
Keywords: لپه; AD; Alzheimer's disease; ANK; ankyrin repeat domain; ARM; armadillo repeat domain; AUC; area under the curve; BA; brain availability; BBB; blood brain barrier; BCRP; breast cancer related protein; BI; brain impairment; CSD; Cambridge Structural Database
Substituted azaquinazolinones as modulators of GHSr-1a for the treatment of type II diabetes and obesity
Keywords: لپه; Diabetes; Obesity; Azaquinazolinone; Ghrelin; Prosidion; LipE
Structure based design of an in vivo active hydroxamic acid inhibitor of P. aeruginosa LpxC
Keywords: لپه; LpxC; Antibacterial; Gram negative; Structure based drug design; Hydroxamic acid; Pseudomonas aeruginosa; LipE; Lipophilic efficiency; Computer aided drug design
Discovery of PF-184563, a potent and selective V1a antagonist for the treatment of dysmenorrhoea. The influence of compound flexibility on microsomal stability
Keywords: لپه; V1a antagonists; Triazoles; LiPE; Lead optimisation; Number of rotatable bonds
3-(Pyridin-2-yl-ethynyl)benzamide metabotropic glutamate receptor 5 negative allosteric modulators: Hit to lead studies
Keywords: لپه; mGluR5; Negative allosteric modulator; Anxiolytic; LipE;
Expression of 11β-hydroxysteroid dehydrogenase type 1 in visceral and subcutaneous adipose tissues of patients with polycystic ovary syndrome is associated with adiposity
Keywords: لپه; PCOS; 11β-HSD1; Glucocorticoids; Obesity; HOMA-IR; Plasma lipids; LPL; LIPE; PPARG; Adiponectin; GLUT4
Azaindole N-methyl hydroxamic acids as HIV-1 integrase inhibitors-II. The impact of physicochemical properties on ADME and PK
Keywords: لپه; HIV integrase; Azaindole hydroxamates; Antiviral; ADME; PK; Log D; LipE; Physicochemical parameters
Rapid assessment of a novel series of selective CB2 agonists using parallel synthesis protocols: A Lipophilic Efficiency (LipE) analysis
Keywords: لپه; CB2; Agonist; Lipophilicity; LiPE; Parallel synthesis;
Characterization of Beta3-Adrenoceptors in Human Internal Mammary Artery and Putative Involvement in Coronary Artery Bypass Management
Keywords: لپه; Ach; acetylcholine; CABG; coronary artery bypass graft; IMA; internal mammary artery; LIPE; hormone-sensitive lipase; L-NMMA; NG-monomethyl-L-arginine monoacetate; NO; nitric oxide; PE; phenylephrine; RT-PCR; reverse transcription-polymerase chain reactio