Keywords: PE; preeclampsia; ePE; experimental preeclampsia; Preg; pregnant; Nonpreg; nonpregnant; WM; white matter; PA; parenchymal arteriole; KIR; inward rectifier potassium channel; IK; intermediate-conductance calcium-activated potassium channel; SK; Small-condu
مقالات ISI (ترجمه نشده)
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Keywords: 4-HNE; 4-hydroxynonenal; AD; Alzheimer's disease; ApoE-/- mice; Apolipoprotein E null mice; BBB; blood brain barrier; CD-36 receptor; cluster of differentiation 36 receptor; CNS; central nervous system; DIO; diet-induced obesity; FA; filtered air; HF; hig
Keywords: CAD; coronary artery disease (CAD); CNTs; carbon nanotubes; COX-2; cyclooxygenase-2; CVD; cardiovascular disease; DHE; dihydroethidium; DQ-gelatin; dye quenched-gelatin; ECM; extracellular matrix; ET-1; endothelin-1; FA-CT; filtered air control; ICAM-1; i
Keywords: Flavonoids; Quercetin; Plant-derived polyphenol; Cardiovascular action; Bioassay; CVD; Cardiovascular disease; eNOS; endothelial nitric oxide synthase; BcL2; B-cell lymphoma 2; MDA; malonaldehyde; TNFα; tumor necrosis factor α; IL-6; Interleukin 6; PPAR
Keywords: Vegetable oils; Beneficial effects; Repeatedly heated oils; Adverse effect; CVD; ABTS-2; 2â²-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid); ACE; angiotensin converting enzymes; ALA; alpha linolenic acid; ALP; alkaline phosphatase; ALT; alanine trans
Keywords: 1-OHP; 1-hydroxypyrene; 3-NT; 3-nitrotyrosine; 8-oxodGuo; 8-oxo-7,8-dihydro-2'-deoxyguanosine; 15-F2t-IsoP; 15-F2t-isoprostane; +dP/ dt; rate of change of pressure development; -dP/dt; rate of change of pressure decay; Ach; acetylcholine; p-AKT; phospho
Keywords: Oxysterols; Survival; Nrf2; Autophagy; 5,6-S; 5,6-secosterol; 24OH; 24-hydroxycholesterol; 25OH; 25-hydroxycholesterol; 27OH; 27-hydroxycholesterol; 7K; 7-ketocholesterol; 7βOH; 7β-hydroxycholesterol; AGE; advanced glycation end products; AMPK; AMP-acti
C1q tumor necrosis factor-related protein 9 in atherosclerosis: Mechanistic insights and therapeutic potential
Keywords: CTRP9; AdipoR1; N-cadherin; Atherosclerosis; Adiponectin; CVD; cardiovascular disease; CTRPs; C1q tumor necrosis factor-related proteins; AMI; acute myocardial infarction; HMW; high molecular weight; AMPK; adenosine monophosphate-activated protein kinase;
MicroRNA-98 regulates foam cell formation and lipid accumulation through repression of LOX-1
Keywords: MiR-98; LOX-1; Ox-LDL; Foam cells;
Exercise intervention attenuates hyperhomocysteinemia-induced aortic endothelial oxidative injury by regulating SIRT1 through mitigating NADPH oxidase/LOX-1 signaling
Keywords: HHcy; hyperhomocysteinemia; Hcy; homocysteine; LOX-1; lectin-like oxidized low density lipoprotein receptor-1; PKC; protein kinase C; SIRT1; sirtuin 1; CAD; coronary artery disease; SOD; superoxidase dismutase; GPx; glutathione peroxidase; and AMPK; AMP-a
Neutrophils and PMN-MDSC: Their biological role and interaction with stromal cells
Keywords: BM; bone marrow; BV8; prokineticin 2; CHOP; C/EBP homologous protein; EMT; epithelial-mesenchymal transition; ER; endoplasmic reticulum; G-CSF; granulocyte colony stimulating factor; GM-CSF; granulocyte-macrophage-colony stimulating factor; HBV; hepatit
Fluid shear stress regulates the expression of Lectin-like oxidized low density lipoprotein receptor-1 via KLF2-AP-1 pathway depending on its intensity and pattern in endothelial cells
Keywords: Fluid shear stress; Vascular endothelial cells; LOX-1; Mechanosensory complex; Kruppel-like factor 2; Activator protein-1;
LOX-1 mediated phenotypic switching of pulmonary arterial smooth muscle cells contributes to hypoxic pulmonary hypertension
Keywords: LOX-1; Pulmonary hypertension; Pulmonary vascular remodeling; Pulmonary arterial smooth muscle cells; Phenotype switching; Dedifferentiation;
Efferocytosis in atherosclerotic lesions: Malfunctioning regulatory pathways and control mechanisms
Keywords: ABC; ATP-binding cassette; ABCA1; ATP-binding membrane cassette transporter A1; ABCG1; ATP binding cassette transporter G1; ABCA7; ATP-binding cassette transporters A7; Abs; Antibodies; ACs; Apoptotic cells; AICAR; 5-aminoimidazole-4-carboxamide-1-β-d-ri
MicroRNA-23a-5p promotes atherosclerotic plaque progression and vulnerability by repressing ATP-binding cassette transporter A1/G1 in macrophages
Keywords: Atherosclerosis; miR-23a-5p; ABCA1/ABCG1; Foam cell formation; Plaque vulnerability; AIS; acute ischemic stroke; ACS; acute coronary syndromes; CAD; coronary artery disease; CEUS; Contrast-enhanced ultrasound; miRNAs; MicroRNAs; 3â² UTR; 3â² untranslate
Contribution of lectin-like oxidized low-density lipoprotein receptor-1 and LOX-1 modulating compounds to vascular diseases
Keywords: LOX-1; Endothelial dysfunction; Atherosclerosis; Pharmacological therapy: microRNAs; ACE; angiotensin converting enzyme; Ang II; Angiotensin II; AT1R; angiotensin II receptor type 1; CCB; calcium channel blocker; CRP; C-reactive protein; eNOS; endothelial
Inhibition of semicarbazide-sensitive amine oxidase reduces atherosclerosis in apolipoprotein E-deficient mice
Keywords: A7r5 hSSAO/VAP-1 cells; A7r5 cells overexpressing VAP-1/SSAO; AGE; advanced glycation end product; ALE; advanced lipoxidation end product; ALT; alanine transaminase; ApoE; apolipoprotein E; AST; aspartate aminotransferase; BMI; body mass index; CAD; coron
Enhanced radical scavenging activity of a procyanidin B3 analogue comprised of a dimer of planar catechin
Keywords: OxLDL; oxidized low-density lipoprotein; LOX-1; lectin-like oxidized low-density lipoprotein receptor; LDL; low-density lipoprotein; ROS; reactive oxygen species, NF-κB, nuclear factor-kappa B; DDQ; 2,3-dichloro-5,6-dicyano-p-banzoquinone, TMSOTf, triflu
The sirtuin family members SIRT1, SIRT3 and SIRT6: Their role in vascular biology and atherogenesis
Keywords: Atherosclerosis; CVD; Sirtuin; SIRT1; SIRT3; SIRT6; Oxidative stress; Lipid metabolism; ABC; Adenosine triphosphate binding cassette; ABCG; ABC sub-family G member; ADP; Adenosine diphosphate; AMPK; Adenosine monophosphate-activated protein kinase; eNOS;
Involvement of epithelial-mesenchymal transition afforded by activation of LOX-1/ TGF-β1/KLF6 signaling pathway in diabetic pulmonary fibrosis
Keywords: LOX-1; TGF-β1; KLF6; Epithelial-mesenchymal transition; Diabetes; Pulmonary fibrosis;
LOX-1 promotes right ventricular hypertrophy in hypoxia-exposed rats
Keywords: LOX-1; NADPH oxidase; ROS; Cell hypertrophy; RVH;
LOX-1 is involved in IL-1β production and extracellular matrix breakdown in dental peri-implantitis
Keywords: Peri-implantitis; Innate immunity; P. gingivalis; LOX-1; IL-1β; MMP2/9;
SIRT1 inhibition causes oxidative stress and inflammation in patients with coronary artery disease
Keywords: CAD; SIRT1; Oxidative stress; LOX-1;
Lectin-like oxidized low-density lipoprotein receptor-1 promotes endothelial dysfunction in LDL receptor knockout background
Keywords: LOX-1; Dyslipidemia; Reactive oxygen species; Endothelial dysfunction; ACh; acetylcholine; ANOVA; analysis of variance; bLOX-1tg; bovine LOX-1 transgenic mice; CD; control diet; eNOS; endothelial nitric oxide synthase; Ldlrâ/â; low-density lipoprotein
Innate immunity related pathogen recognition receptors and chronic hepatitis B infection
Keywords: acLDL; acylated LDL; AIM2; absent in melanoma 2; AP-1; activator protein 1; BDCA-2; blood DC antigen; BEC; biliary epithelial cells; CARD; caspase recruitment and activation domains; cDC; common dendritic cells; CL-L1; collectin liver 1; CL-K1; collectin
Varenicline enhances oxidized LDL uptake by increasing expression of LOX-1 and CD36 scavenger receptors through α7 nAChR in macrophages
Keywords: nAChR; nicotinic acetylcholine receptor; oxLDL; oxidized low-density lipoprotein; LOX-1; lectin-like oxidized LDL receptor-1; CD36; cluster of differentiation 36; SR-A; scavenger receptor class A; MLA; methyllycaconitine; DHβE; dihydro-β-erythroidine hy
Oxidized LDL at the crossroads of immunity in non-alcoholic steatohepatitis
Keywords: 25HC; 25-hydroxycholesterol; 27HC; 27-hydroxycholesterol; 4-HNE; 4-hydroxynonenal; CASP-1; Caspase-1; CD36; cluster of differentiation 36; Col1a1; collagen type 1, alpha 1; CONV-R; conventionally raised; CVD; cardiovascular disease; FA; fatty acid; FXR; f
The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARγ
Keywords: 7-Ketocholesteryl-9-carboxynonanoate; Oxidized low-density lipoprotein; LOX-1; PPARγ; ABCA1;
LOX-1: A potential target for therapy in atherosclerosis; an in vitro study
Keywords: LOX-1R; Lectin like oxidized LDL receptor,; oxLDL; oxidized LDLR; siLOX-1; siRNA against LOX-1 receptor mRNA; LOXTRV; LOX-1 transcript variants; TRV; transcript variants; LOX-1; siRNA; Atherosclerosis; OxLDL; Monocytes/Macrophage; TNF-α; IL-6; NF-kB;
Negative feedback regulation between microRNA let-7g and LOX-1 mediated hypoxia-induced PASMCs proliferation
Keywords: HPH; LOX-1; let-7g; microRNA; Cell proliferation; Negative feedback;
Dual signaling evoked by oxidized LDLs in vascular cells
Keywords: AAPH; 2,2'-azobis(2-amidinopropane) dihydrochloride; AIF; apoptotic inducing factor; AMVN; 2,4-dimethylvaleronitrile; AP-1; activator protein 1; ATF6; activating transcription factor 6; CDE; clathrin-dependent endocytosis; CCL2; chemokine ligand 2 (or MCP
ox-LDL induces endothelial dysfunction by promoting Arp2/3 complex expression
Keywords: Arp2/3; ox-LDL; LOX-1; Rac-1; Endothelial dysfunction
LOX-1 and TLR4 affect each other and regulate the generation of ROS in A. fumigatus keratitis
Keywords: Aspergillus fumigatus; Keratitis; LOX-1; TLR4; ROS;
Protective effect of Naoxintong against cerebral ischemia reperfusion injury in mice
Keywords: NXT; Naoxintong; tMCAO; Transient Middle Cerebral Artery Occlusion; IHC; Immunohistochemistry; qRT-PCR; Quantitative Reverse Transcription-Polymerase Chain Reaction; LOX-1; Lectin-like Oxidized Low-Density Lipoprotein Receptor-1; ERK; Extracellular Regula
AMP-activated protein kinase attenuates oxLDL uptake in macrophages through PP2A/NF-κB/LOX-1 pathway
Keywords: AICAR (PubChem CID: 17513); PDTC (PubChem CID: 2209); Okadaic acid (PubChem CID: 446512); Compound C (PubChem CID: 11524144); AMPK; Macrophage; oxLDL uptake; LOX-1; Atherosclerosis;
Collectin CL-P1 utilizes C-reactive protein for complement activation
Keywords: CRP; C-reactive protein; PTX3; pentraxin 3; CRD; carbohydrate recognition domain; Col; collagen; TCC; terminal complement complex; SR; scavenger receptor; CL-P1; collectin placenta 1; SR-AI; scavenger receptor type I; LOX-1; lectin-like oxidized LDL recep
The neutral sphingomyelinase-2 is involved in angiogenic signaling triggered by oxidized LDL
Keywords: Cer; ceramide; CAM; chorioallantoic membrane; HMEC-1; Human Microvascular Endothelial Cell-1; LDL; low density lipoproteins; mAb; monoclonal antibodies; nSMase2; neutral sphingomyelinase-2; oxLDL; oxidized LDL; ROS; reactive oxygen species; H2O2; hydrogen
Carbamylated Low-Density Lipoproteins Induce a Prothrombotic State Via LOX-1
Keywords: aggregation; arterial thrombosis; chronic kidney disease; platelets; vascular smooth muscle cells; AoSMC; aortic smooth muscle cell; CKD; chronic kidney disease; cLDL; carbamylated low-density lipoprotein; HAEC; human aortic endothelial cell; LDL; low-de
“Benifuuki” green tea, containing O-methylated EGCG, reduces serum low-density lipoprotein cholesterol and lectin-like oxidized low-density lipoprotein receptor-1 ligands containing apolipoprotein B: A double-blind, placebo-controlled randomized trial
Keywords: Dyslipidaemia; Benifuuki; O-methylated catechin; Lectin-like oxidized LDL receptor-1; LOX-1 ligand containing apolipoprotein B; EGCG; (â)-Epigallocatechin-3-O-gallate; EGCGâ³3Me; (â)-epigallocatechin-3-O-(3-O-methyl)-gallate; HDL; high-density lipopr
Roles of LOX-1 in microvascular dysfunction
Keywords: oxLDL receptor; LOX-1; Free radicals; Oxidative stress; Endothelial function; Microcirculation;
Elevation of circulating LOX-1 ligand levels in Zucker obese and diabetic rats
Keywords: Diabetes mellitus; LOX-1; Obesity; Oxidative stress; Zucker ratsANOVA, analysis of variance; HDL, high-density lipoprotein; LAB, LOX-1 ligands containing apolipoprotein B; LDL, low-density lipoprotein; LDL-C/HDL-C ratio, ratio of LDL cholesterol to HDL ch
Oxidized LDL attenuates protective autophagy and induces apoptotic cell death of endothelial cells: Role of oxidative stress and LOX-1 receptor expression
Keywords: Oxidized-LDL; LOX-1; Oxidative stress; Protective autophagy;
Increased LDL electronegativity in chronic kidney disease disrupts calcium homeostasis resulting in cardiac dysfunction
Keywords: Apo; apolipoprotein; CKD; chronic kidney disease; EDPVR; end-diastolic pressure-volume relationship; ESPVR; end-systolic pressure-volume relationship; HDL; high-density lipoprotein; LDL; low-density lipoprotein; LOX-1; lectin-like oxidized LDL recepto
Hemodynamic shear stress modulates endothelial cell autophagy: Role of LOX-1
Keywords: Shear stress; LOX-1; Autophagy; Inflammation;
High glucose activates Raw264.7 macrophages through RhoA kinase-mediated signaling pathway
Keywords: AGE; Advanced glycation endproduct; AP-1; Activator protein 1; CVD; Cardiovascular disease; DM; Diabetes mellitus; ERK; Extracellular regulated protein kinase; HF; Hydroxyfasudil; HG; High glucose; IKK; IκB kinase; JNK; c-Jun N-terminal kinase; LDL; Low
Modulation of oxidized-LDL receptor-1 (LOX1) contributes to the antiatherosclerosis effect of oleanolic acid
Keywords: Ox-LDL; oxidized low density lipoprotein; HUVECs; human umbilical vein endothelial cells; MTT; 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide; DCFDA; 2â²,7â²-dichlorofluorescein diacetate; ROS; reactive oxygen species; OA; oleanolic a
Pure peptides from amaranth (Amaranthus hypochondriacus) proteins inhibit LOX-1 receptor and cellular markers associated with atherosclerosis development in vitro
Keywords: Amaranth; Atherosclerosis; LOX-1; Peptides;
Oxidized LDL and NO synthesis-Biomarkers of endothelial dysfunction and ageing
Keywords: LDL; low-density lipoprotein; oxLDL; oxidized low-density lipoprotein; LOX-1; lectin-like oxidized LDL receptor-1; FFA; free fatty acids; ApoB-100; apolipoprotein B-100; H2O2; hydrogen peroxide; SOD; superoxide dismutase; ROS; reactive oxygen species; O2â
Role of Nrf2 in the pathogenesis of atherosclerosis
Keywords: ABCA1; ATP-binding cassette, sub-family A, member 1; ABCG1; ATP-binding cassette, sub-family G, member 1; ApoE; apolipoprotein E; ARE; antioxidant response element; ArgII; arginase II; CDDO-Im; 2-cyano-3,12 dioxooleana-1,9 dien-28-imidazolide; CXCL4; chem
LOX-1 expression and oxidized LDL uptake and toxicity in the HN33 neuronal cell line
Keywords: Neurodegeneration; LOX-1; Ox-LDL; HN33 cells; HypoxiaDiI, 1, 1’-dioctadecyl-3,3,3’,3’-tetramethyl-indocarbocyanine perchlorate; LOX-1, oxidized low-density lipoprotein receptor-1; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; Ox-LDL,