Ras/MAP Kinase pathways are involved in Ras specific apoptosis induced by sodium butyrate
Keywords: کیناز MAP; Sodium butyrate; Apoptosis; Ras; MAP kinase; ERK;
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Proteomic identification of glyceraldehyde 3-phosphate dehydrogenase as an inhibitory target of hydrogen peroxide in Arabidopsis
Keywords: کیناز MAP; Arabidopsis thaliana; Glyceraldehyde 3-phosphate dehydrogenase; Hydrogen peroxide; Proteomics; Reactive oxygen species signalling; DMSO; dimethyl sulfoxide; DTT; dithiothreitol; 5â²-IAF; 5â²-iodoacetamide fluorescein; LC-ESI-MS/MS; liquid chromatography
Disruption of two putative nuclear localization sequences is required for cytosolic localization of mitogen-activated protein kinase phosphatase-2
Keywords: کیناز MAP; MKP; MAP kinase; NLS; Nuclear localization;
Inhibition of epidermal growth factor-induced cell transformation by tannins
Keywords: کیناز MAP; AP-1; activator protein 1; BME; basal medium Eagle; DMSO; dimethylsulfoxide; DTT; dithiothreitol; EBV-EA; Epsten-Barr virus early antigen; EGCG; (â)-epigallochatechin-3-gallate; EGF; epidermal growth factor; EGFR; EGF receptor; ERKs; extracellular-sig
Integration of progesterone receptor mediated rapid signaling and nuclear actions in breast cancer cell models: Role of mitogen-activated protein kinases and cell cycle regulators
Keywords: کیناز MAP; Progesterone receptor; MAP Kinase; Cyclin-dependent protein kinase; Cyclin D1; Breast cancer; Cell cycle progression;
FK1706, a novel non-immunosuppressive immunophilin: neurotrophic activity and mechanism of action
Keywords: کیناز MAP; Immunophilin; Nerve growth factor; MAP kinase; Neurite outgrowth;
Developmental regulation of activated ERK expression in the spinal cord and dorsal root ganglion of the chick embryo
Keywords: کیناز MAP; MAP kinase; Oligodendrocyte; Dorsal horn; Spinal nerve; Immunohistochemistry;
Food restriction increases NMDA receptor-mediated calcium-calmodulin kinase II and NMDA receptor/extracellular signal-regulated kinase 1/2-mediated cyclic amp response element-binding protein phosphorylation in nucleus accumbens upon D-1 dopamine receptor
Keywords: کیناز MAP; food restriction; NMDA receptor; MAP kinase; nucleus accumbens; D1 receptor; AL; ad libitum fed; ANOVA; analysis of variance; CaMK II; calcium-calmodulin kinase II; CREB; cyclic AMP response element-binding protein; DA; dopamine; ECL; enhanced chemilumi
cAMP-response element-binding protein mediates prostaglandin F2α-induced hypertrophy of vascular smooth muscle cells
Keywords: کیناز MAP; Prostaglandins; Hypertrophy; Vascular smooth muscle cells; Signal transduction; MAP kinase; cAMP-response element-binding protein;
Curcumin suppresses phorbol ester-induced matrix metalloproteinase-9 expression by inhibiting the PKC to MAPK signaling pathways in human astroglioma cells
Keywords: کیناز MAP; Curcumin; Astroglioma; Matrix metalloproteinase-9; NF-κB; AP-1; PKC; MAP kinase; Gene expression; Signal transduction;
Francisella tularensis LVS initially activates but subsequently down-regulates intracellular signaling and cytokine secretion in mouse monocytic and human peripheral blood mononuclear cells
Keywords: کیناز MAP; Francisella tularensis; activation; NF-κB; MAP kinase; TNF-α;
H2O2 Accumulation by Catalase Reduction Changes MAP Kinase Signaling in Aged Human Skin In Vivo
Keywords: کیناز MAP; skin; aging; MAP kinase; catalase; H2O2; MMP-1;
Exposure to toxic concentrations of aluminum activates a MAPK-like protein in cell suspension cultures of Coffea arabica
Keywords: کیناز MAP; Aluminum toxicity; Coffee cell suspension cultures; MAP kinase-like activity; BSA; bovine serum albumin; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol-bis(aminoethylether)-N,N,Nâ²,Nâ²-tetraacetic acid; ERK; extracellular signal-regulated
Inhibition of sphingolipid biosynthesis decreases phosphorylated ERK2 in LLC-PK1 cells
Keywords: کیناز MAP; Fumonisin B1; Sphingolipids; LLC-PK1 cells; MAP Kinase; ERK2;
ERK1/2 activation by angiotensin II inhibits insulin-induced glucose uptake in vascular smooth muscle cells
Keywords: کیناز MAP; Insulin resistance; Angiotensin II; Vascular smooth muscle cell; Glucose uptake; MAP kinase; IRS-1;
Uptake of LPS/E. coli/latex beads via distinct signalling pathways in medfly hemocytes: the role of MAP kinases activation and protein secretion
Keywords: کیناز MAP; MAPK; mitogen-activated protein kinase; ERK; extracellular-signal regulated kinase; MEK; MAPK/ERK Kinases; GRB2; growth factor receptor-bound protein 2; JNK; c-jun N-terminal kinase; MAP kinase; Protein secretion; Phagocytosis; LPS; E. coli; Insect immuni
Following in vitro activation of mitogen-activated protein kinases by mass spectrometry and tryptic peptide analysis: purifying fully activated p38 mitogen-activated protein kinase α
Keywords: کیناز MAP; MAP kinase; p38 MAPKα; Purification; Activation; Kinetics;
Connexin43 synthesis, phosphorylation, and degradation in regulation of transient inhibition of gap junction intercellular communication by the phorbol ester TPA in rat liver epithelial cells
Keywords: کیناز MAP; Cell communication; Gap junctions; Connexin 43; Degradation; Phosphorylation; Tetradecanoylphorbol acetate; Protein kinase C; MAP kinase;
Activation of mitogen activated protein kinase pathways and melanogenesis by novel nitro-derivatives of 7-hydroxycomarin in human malignant melanoma cells
Keywords: کیناز MAP; 6-Nitro-7-hydroxycoumarin; 3,6,8-Trinitro-7-hydroxycoumarin; Malignant melanoma; Melanogenesis; MAP kinase; Differientation;
TGF-β1 induces cardiac hypertrophic responses via PKC-dependent ATF-2 activation
Keywords: کیناز MAP; Cytokine; Hypertrophy; MAP kinase; Myocyte; Protein phosphorylation; ANF; atrial natriuretic factor; Ang II; angiotensin II; ATF; activating transcription factor; BNP; brain natriuretic peptide; DN; dominant negative; ET-1; endothelin-1; MAPKKK; mitogen-a
Quantitative proteomic analysis of fibroblast nuclear proteins after stimulation with mitogen activated protein kinase inhibiting heparan sulfate
Keywords: کیناز MAP; Cell growth; Fibroblast; Heparan sulfate; Mitogen-activated protein kinase (MAP kinase); Signal transduction; bFGF; basic fibroblast growth factor; CS; chondroitin sulfate; DS; dermatan sulfate; DexS; dextran sulfate; EGF; epidermal growth factor; EMEM; E
MAPK signalling pathways as molecular targets for anti-inflammatory therapy-from molecular mechanisms to therapeutic benefits
Keywords: کیناز MAP; ARE; AU-rich element; ASK; Apoptosis Signal regulating Kinase; ATF-2; Activating Transcription Factor 2; CRE; Cyclic AMP Responsive Element; ERK; Extracellular signal regulated kinase; iNOS; inducible Nitric Oxide Synthase; JNK; c-Jun N-terminal Kinase; L
Substrate specificity of protein kinases and computational prediction of substrates
Keywords: کیناز MAP; AGC; protein kinases A, G, C; AMPK; AMP-activated protein kinase; CaMK; calmodulin-dependent kinase; CDK; cyclin-dependent kinase; CMGC kinases; cyclin-dependent kinases, MAP kinases, glycogen synthase kinase 3 (GSK3) and CK2-related protein kinases; FRET
Syndecan-2 overexpression induces osteosarcoma cell apoptosis: Implication of syndecan-2 cytoplasmic domain and JNK signaling
Keywords: کیناز MAP; Syndecan; Apoptosis; Osteosarcoma cells; Signaling; MAP kinase;
A pro- and an anti-inflammatory cytokine are synthetised in distinct brain macrophage cells during innate activation
Keywords: کیناز MAP; BM; brain macrophages; DC; dendritic cells; LPS; lipopolysaccharide; TNF; tumour necrosis factor; MAPK; MAP kinase; Toll like receptor; Microglia subsets; CNS;
IGF-I protects cortical neurons against ceramide-induced apoptosis via activation of the PI-3K/Akt and ERK pathways; is this protection independent of CREB and Bcl-2?
Keywords: کیناز MAP; Development and regeneration; Neuronal death; Ara-C; Cytosine arabinoside; BSA; Bovine serum albumin; CaMKIV; Calcium-calmoduline kinase IV; CAPP; Ceramide activated protein phosphatase; cer: c2-ceramide; CREB; CAMP-response element binding protein; ECLEn
Extracellular signal-regulated kinase-1 and -2 are activated by gastric luminal injury in dorsal root ganglion neurons via n-methyl-d-aspartate receptors
Keywords: کیناز MAP; retrograde tracing; MAP kinase; TRPV1; MK-801; hypersensitivity; DRG; dorsal root ganglion; ERK 1/2; extracellular signal-regulated kinase-1 and -2; NF200; neurofilament 200; NMDA; N-methyl-d-aspartate; PBS; phosphate-buffered saline; pERK 1/2; phosphoryl
Electroacupuncture regulates NMDA receptor NR1 subunit expression via PI3-K pathway in a rat model of cerebral ischemia-reperfusion
Keywords: کیناز MAP; Disorders of nervous system; Ischemia; Cerebral ischemia; Electroacupuncture; NMDA receptor subunit; TrkA; MAP kinase; PI3-kinase;
Relationship between constitutive nuclear factor-kappaB (NF-κB) and inhibitor kappaB-alpha (IκB-α) in an interferon-α-sensitive human Burkitt lymphoma cell line
Keywords: کیناز MAP; Constitutive NF-κB; IκB-α; Interferon-α; Cell proliferation; MAP kinase; Burkitt lymphoma;
APC/C-Cdc20-mediated degradation of cyclin B participates in CSF arrest in unfertilized Xenopus eggs
Keywords: کیناز MAP; Cytostatic factor; Metaphase II arrest; Xenopus egg; Cyclin B degradation; The anaphase-promoting complex/cyclosome; Cdc20; Mos; MAP kinase;
Differential roles of p39Mos-Xp42Mpk1 cascade proteins on Raf1 phosphorylation and spindle morphogenesis in Xenopus oocytes
Keywords: کیناز MAP; Spindle formation; p39Mos; MAP Kinase; Meiosis; Xenopus;
Control of reproductive processes by growth hormone: Extra- and intracellular mechanisms
Keywords: کیناز MAP; Growth hormone; Insulin-like growth factor I; Insulin-like growth factor binding protein 3; Oxytocin; cAMP; Protein kinase A; Protein kinase G; Tyrosine kinase; MAP kinase; CDC2 kinase;
Role of cytosolic phospholipase A2 in the enhancement of α2-adrenoceptor-mediated vasoconstriction by the thromboxane-mimetic U46619 in the porcine isolated ear artery: Comparison with vasopressin-enhanced responses
Keywords: کیناز MAP; AEBSF; 4-(2-aminoethyl)benzenesulphonyl fluoride; ANOVA; analysis of the variance; E-64; trans-epoxysuccinyl-l-leucylamide-(4-guanidino) butane; ERK; extracellular signal-regulated kinase; HELSS; Haloenol lactone suicide substrate; MAP kinase; mitogen-act
Urocortin 2 induces tyrosine hydroxylase phosphorylation in PC12 cells
Keywords: کیناز MAP; Corticotropin-releasing factor; Urocortin 2; Noradrenaline; PKA; MAP kinase; Tyrosine hydroxylase;
Short chain fatty acids regulate tyrosine hydroxylase gene expression through a cAMP-dependent signaling pathway
Keywords: کیناز MAP; Neurotransmitters, modulators, transporters, and receptors; Catecholamines; SCFA; short chain fatty acids; SB; sodium butyrate; PKA; protein kinase A; cAMP; cyclic adenosine mono phosphate; CREB; cAMP response element binding protein; CRE; cAMP response e
Expression, purification, and enzymatic characterization of the dual specificity mitogen-activated protein kinase phosphatase, MKP-4
Keywords: کیناز MAP; Dual specificity phosphatase; Protein tyrosine phosphatase superfamily; Type 2 diabetes; MAP kinase; Insulin signaling; Diabetes mellitus;
Mechanisms involved in the nociception produced by peripheral protein kinase c activation in mice
Keywords: کیناز MAP; Protein kinase C; Phorbol ester; Glutamate; Substance P; MAP kinase; Nociception; Mice;
Antiangiogenic activity of β-eudesmol in vitro and in vivo
Keywords: کیناز MAP; Angiogenesis; Endothelial cell; Growth; Migration; Tube formation; MAP kinase;
Molecular mechanisms of the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced inverted U-shaped dose responsiveness in anchorage independent growth and cell proliferation of human breast epithelial cells with stem cell characteristics
Keywords: کیناز MAP; Dioxin; TCDD; Human breast cancer; Anchorage independent growth; Breast tumorigenesis; Inverted U-shaped responsiveness; MAP kinase; Cell signaling;
Insulin, glucagon and fatty acid treatment of hepatocytes does not result in phosphorylation or changes in activity of triacylglycerol hydrolase
Keywords: کیناز MAP; Apo; apolipoprotein; ATGL; adipose triglyceride lipase; BSA; bovine serum albumin; BSDL; bile salt-dependent lipase; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; FBS; fetal bovine serum; HS; horse serum; HSL; hormone sensitive lipa
Purification and kinetic characterization of recombinant human mitogen-activated protein kinase kinase kinase COT and the complexes with its cellular partner NF-κB1 p105
Keywords: کیناز MAP; COT; Tpl-2; NF-κB1 p105; MAP kinase; MAP3 kinase; Metal cofactor; Kinetic; Km; kcat; Regulation; Mechanism;
Baker's yeast as a tool for the development of antifungal kinase inhibitors-targeting protein kinase C and the cell integrity pathway
Keywords: کیناز MAP; DAG; diacyl glycerol; FACS; fluorescent activated cell sorting; GAP; GTPase activating protein; GEF; GDP/GTP exchange factor; GFP; green fluorescent protein; HR1; homology region 1; MAPK(KK); mitogen activated protein kinase (kinase kinase); PKC; protein
Induction of apoptosis in the lung tissue from rats exposed to cigarette smoke involves p38/JNK MAPK pathway
Keywords: کیناز MAP; CS; cigarette smoke; MAPK; mitogen-activated protein kinases family; JNK; c-Jun N-terminal kinase; ERK2; extracellular signal regulating kinase2; FasL; Fas ligand; PKC-α; protein kinase C-α; STAT1; signal transducer and activated of transcription; MEK1;
Germinal vesicle materials are requisite for male pronucleus formation but not for change in the activities of CDK1 and MAP kinase during maturation and fertilization of pig oocytes
Keywords: کیناز MAP; CDK1; Germinal vesicle; Male pronucleus; MAP kinase; Sperm head decondensation;
Signaling by Kit protein-tyrosine kinase-The stem cell factor receptor
Keywords: کیناز MAP; Akt; APS; Bad; Cancer; Cbl; Dok1; Erk; Fyn; Grb2; Grb7; Hematopoiesis; Leukemia cell lines; Lyn; MAP kinase; Mast cell; Oncogene; Piebaldism; Protein kinase; Protein phosphatase; Proto-oncogene; Ras; Shp1; Shp2; Src family kinase;
Activation of c-Jun NH2-terminal kinase (JNK) signaling pathway is essential for the stimulation of hepatitis C virus (HCV) non-structural protein 3 (NS3)-mediated cell growth
Keywords: کیناز MAP; HCV NS3; HCC; MAP kinase; JNK; Cell growth;
Ethanol induces the production of cytokines via the Ca2+, MAP kinase, HIF-1α, and NF-κB pathway
Keywords: کیناز MAP; Mast cells; TNF-α; TGF-β1; Alcohol; MAP kinase; HIF-1α; NF-κB
Activation of p38 and p42/44 MAP kinase in neuropathic pain: Involvement of VPAC2 and NK2 receptors and mediation by spinal glia
Keywords: کیناز MAP; MAP kinase; mitogen-activated protein kinase; TNF-α; tumor necrosis factor-α; PPT; propentofylline; VIP; vasoactive intestinal polypeptide; PACAP; pituitary adenylate cyclase-activating peptide; CCI; chronic constriction injury;
A MAPK pathway is involved in the control of mitosis after fertilization of the sea urchin egg
Keywords: کیناز MAP; MAP kinase; Egg; Sea urchin; ERK; Mitosis; Fertilization; Mitotic spindle;
Progressive left ventricular remodeling, myocyte apoptosis, and protein signaling cascades after myocardial infarction in rabbits
Keywords: کیناز MAP; Apoptosis; Infarction; MAP kinase; Mitochondria; Oxygen radical;