دانلود مقالات ISI درباره Map Kinase Kinase + ترجمه فارسی

ژنومیک سرطان پستان و نشانگرهای ایمنی و انکولوژیک برای هدایت درمان های ایمنی

Breast cancer genomics and immuno-oncological markers to guide immune therapies

Keywords: APC; antigen presenting cell; APOBEC; apolipoprotein B mRNA editing enzyme catalytic polypeptide-like; BRCA1/2; breast cancer 1/2; BCSS; breast cancer specific survival; B2M; β-2-microglobulin; CAF; cancer associated fibroblast; CCL; chemokine ligand; CD

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

مسیرهای متفاوتی از شکستگی اندام بر روی التهاب میتوکندریا

Mitochondria-meditated pathways of organ failure upon inflammation

Keywords: ADP; adenosine diphosphate; ANT; adenine nucleotide translocator; ATP; adenosine triphosphate; Bax; BCL2-associated X protein; Bcl-xL; B-cell lymphoma-extra large; CLP; cecal ligation and puncture; CyP; cyclophilin; DAMP; damage-associated molecular patte

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

انتقال سیگنال و مکانیزم های اپی ژنتیک در کنترل فعال سازی میکروگلایز در عفونت های عصبی

Signal transduction and epigenetic mechanisms in the control of microglia activation during neuroinflammation

Keywords: AP-1; activator protein 1; APC; antigen-presenting cells; ARE; AU-rich element; ASK; Apoptosis Signal regulating Kinase; ATF-2; Activating Transcription Factor 2; CRE; Cyclic AMP Responsive Element; CBP; CREB binding protein; CsA; ciclosporin A; ERK; Extr

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

سیگنال گیرنده سنجش کلسیم در فیزیولوژی و سرطان

Calcium sensing receptor signalling in physiology and cancer

Keywords: APC; adenomatous polyposis coli; bFGF; basic fibroblast growth factor; Ca2 +i; intracellular calcium; Ca2 +o; extracellular calcium; CaSR; calcium sensing receptor; CDX-2; caudal type homeobox 2; EGF; epidermal growth factor; ERK; extracellular-signal-r

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

گیرنده های سطحی سلول های نوتروفیل و مسیرهای انتقال سیگنال داخل سلولی آنها

Neutrophil cell surface receptors and their intracellular signal transduction pathways

Keywords: Abl; Abelson leukemia proto-oncogene; ADAP; adhesion and degranulation promoting adapter protein (Fyb, SLAP-130); Asc; apoptosis-associated speck-like protein containing a CARD; BCR; B-cell receptor; C3G; Crk SH3 domain-binding guanine nucleotide exchange

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Androgen receptor (AR) degradation enhancer ASC-J9® in an FDA-approved formulated solution suppresses castration resistant prostate cancer cell growth

Keywords: Androgen receptor; Prostate cancer; Prostate therapy; ASC-J9®; IC50; Epithelial cells; Stromal cells; Fibroblasts; Myofibroblasts; Apoptosis; FDA-approved formula; AR; androgen receptor; PCa; prostate cancer; RT-PCR; reverse transcription polymerase chai

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway

Keywords: Akt; oncogene in the transforming retrovirus, AKT8; AP-1; activator protein 1; ARAF; v-raf murine sarcoma 3611 viral oncogene homologue; ASK1; apoptosis signal-regulating kinase 1; BCL2; B-cell lymphoma 2; BCL-XL; B-cell lymphoma extra large; BRAF; v-raf

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2018 سفارش ترجمه

Pervanadate induces Mammalian Ste20 Kinase 3 (MST3) tyrosine phosphorylation but not activation

Keywords: Cys; cysteine; DMEM; Dulbecco's modified Eagle's medium; EGFR; epidermal growth factor receptor; GPCR; G protein-coupled receptor; HEK 293; human embryonic kidney 293; HPK1; hematopoietic progenitor kinase 1; MST; mammalian Ste20 kinase; MAP4K; MAP kinase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Fgf regulates dedifferentiation during skeletal muscle regeneration in adult zebrafish

Keywords: EdU; 5-ethynyl-2′-deoxyuridine; EOM; extraocular muscle; hpi; hours post injury; dpi; days post injury; Fgf; fibroblast growth factor; Fgfr; fibroblast growth factor receptor; LR; lateral rectus; Tc; cell cycle length; Ts; length of S-phase; MAPK; mitog

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

The p21-activated kinase, PAK2, is important in the activation of numerous pancreatic acinar cell signaling cascades and in the onset of early pancreatitis events

Keywords: CCK; COOH-terminal octapeptide of cholecystokinin; TPA; 12-O-tetradecanoylphorbol-13-acetate; PAK; p21-activated kinases; SFK; Src family of kinases; PKC; protein kinase C; PYK2; proline-rich tyrosine kinase 2; FAK; focal adhesion kinase; SHC; Src homolog

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Myrsine seguinii ethanolic extract and its active component quercetin inhibit macrophage activation and peritonitis induced by LPS by targeting to Syk/Src/IRAK-1

Keywords: Ms-EE; ethanolic extract of Myrsine seguinii; PGE2; prostaglandin E2; NO; nitric oxide; COX; cyclooxygenase; iNOS; inducible NO synthase; (TNF)-α; tumour necrosis factor; ERK; extracellular signal-related kinase; TLR; toll-like receptors (TLR); MAPK; mit

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of conserved and novel microRNAs in Manduca sexta and their possible roles in the expression regulation of immunity-related genes

Keywords: Posttranscriptional regulation; Illumina sequencing; Lepidoptera; Insect immunity; Target site prediction; Alk; anaplastic lymphoma kinase; AMP; antimicrobial peptides; ANKRD54; ankyrin repeat domain 54; Aop; anterior open; aPKC; atypical protein kinase C

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Arrestin-3 binds the MAP kinase JNK3α2 via multiple sites on both domains

Keywords: GPCR; G protein-coupled receptor; JNK; c-Jun NH2-terminal protein kinase; MAPK; mitogen-activated protein kinase; MKK or MAPKK; MAP kinase kinase; MAPKKK; MAP kinase kinase kinase; ASK1; Apoptosis signal-regulating kinase 1, a.k.a. mitogen-activated prote

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Research ReportDelayed administration of the nucleic acid analog 2Cl-C.OXT-A attenuates brain damage and enhances functional recovery after ischemic stroke

Keywords: COA-Cl; 2Cl-C.OXT-A; ERK; extracellular signal-regulated kinase; LDH; lactate dehydrogenase; MAPK; mitogen-activated protein kinase; MCAO; middle cerebral artery occlusion; MEK; MAP kinase kinase; OGD; oxygen-glucose deprivation; rCBF; regional cerebral b

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

E-type prostanoid receptor 4 (EP4) in disease and therapy

Keywords: AMPK; AMP-activated protein kinase; cAMP; cyclic adenylyl monophosphate; CFTR; cystic fibrosis transmembrane conductance regulator; ClC; chloride channel; COX; cyclooxygenase; CREB; cAMP-response element-binding protein; DP; D-type prostanoid receptor; DS

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

Crystal and solution structures disclose a putative transient state of mitogen-activated protein kinase kinase 4

Keywords: JNK; c-Jun NH2-terminal kinase; MAP; mitogen-activated protein; MAP2K; MAP kinase kinase; MAP3K; MAP kinase kinase kinase; npMAP2K4; non-phosphorylated MAP2K4; IPTG; isopropyl-β-d-thiogalactopyranoside; ANP; adenylyl-imidodiphosphate; ATP; adenosine trip

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

A continuous spectrophotometric assay for mitogen-activated protein kinase kinases

Keywords: Phosphorylation; Dephosphorylation; MAP kinase; MAP kinase kinase; MAP kinase phosphatase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

MicroRNA 497 modulates interleukin 1 signalling via the MAPK/ERK pathway

Keywords: IL; interleukin; MAPK; mitogen-activated protein kinase; NFκB; nuclear factor κB; AP-1; jun proto-oncogene; ERK; extracellular signal-regulated kinase; JNK; c-Jun amino-terminal kinase; P38; mitogen-activated protein kinase 14; MEK; MAP Kinase kinase; R

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Redox signaling loops in the unfolded protein response

Keywords: AGR2; anterior gradient 2; ARE; antioxidant responsive element; ATF4; activating transcription factor-4; ATF6; activating transcription factor-6; ASK1; apoptosis signal-regulating kinase-1; BI-1; BAX inhibitor-1; BiP; immunoglobulin heavy chain-binding pr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Methanol extract of Osbeckia stellata suppresses lipopolysaccharide- and HCl/ethanol-induced inflammatory responses by inhibiting Src/Syk and IRAK1

Keywords: Os-ME; methanol extract of Osbeckia stellata; PGE2; prostaglandin E2; NO; nitric oxide; COX; cyclooxygenase; iNOS; inducible NO synthase; TNF-α; tumor necrosis factor-alpha; ERK; extracellular signal-related kinase; TLR; toll-like receptor; MAPK; mitogen

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease

Keywords: AD; Alzheimer's disease; AKT; protein kinase B; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor; aPKC; atypical protein kinase C; APP; amyloid-β precursor protein; ATG; AuTophaGy-related; BDNF; brain-derived neurotrophic factor; C/EBP; C

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Trypanosoma brucei: Two mitogen activated protein kinase kinases are dispensable for growth and virulence of the bloodstream form

Keywords: Trypanosoma; Protein kinase; MAP kinase kinase; Gene knockout; Virulence; Stress;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Dual role of NO donors in the reversal of tumor cell resistance and EMT: Downregulation of the NF-κB/Snail/YY1/RKIP circuitry

Keywords: Bcl-xL; B-cell leukemia-xL; CDDP; cis-diammine-dichloro-platinum; DETANONOate; (Z)-1-[2-(2-aminoethyl)-N-(2-ammonio-ethyl) amino] diazen-1-ium-1, 2-diolate; DHMEQ; dehydroxymethylepoxyquinomicin; DR; death receptor; ERK; extracellular signal-regulated kin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders

Keywords: Apoptosis; Brain-derived neurotrophic factor (BDNF); Glycogen synthase kinase 3 (GSK-3); Lithium; Neurodegenerative diseases; Neuroprotection; 3-NP; 3-nitropropionic acid; Aβ; β-amyloid; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AP-1;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2010 سفارش ترجمه

The role of protein synthesis in cell cycling and cancer

Keywords: Cell cycle; Elongation factor 2; Elongation factor 2 kinase; Apoptosis; Cancer; AMPK; AMP-activated Kinase; cAMP; cyclic AMP; PKA; Protein Kinase A; FLIP; FLICE-Like Inhibitor Protein; XIAP; X-linked Inhibitor of Apoptosis; EF2; Elongation Factor 2; cdc2/

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

The Gα4 G protein subunit interacts with the MAP kinase ERK2 using a D-motif that regulates developmental morphogenesis in Dictyostelium

Keywords: PCR; polymerase chain reaction; MAP kinase; mitogen-activated protein kinase; MAPKK; MAP kinase kinase; ERK; extracellular signal-regulated kinase; CD; common docking site; D-motif; MAPK docking site; SDS; sodium dodecyl sulfate; cAMP; cyclic adenosine mo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

AP1 binding site is another target of FGF2 regulation of bone sialoprotein gene transcription

Keywords: BSP; bone sialoprotein; FGF2; fibroblast growth factor 2; FRE; FGF response element; bp; base pair(s); nts; nucleotides; PKC; protein kinase C; PKA; cAMP dependent protein kinase; MAP kinase; mitogen activated protein kinase; MEK; MAP kinase kinase; Pit-1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

A mutation in the Arabidopsis MAP kinase kinase 9 gene results in enhanced seedling stress tolerance

Keywords: MAP kinase; MAP kinase kinase; Abscisic acid; Salt

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Investigation of cell cycle arrest effects of actinomycin D at G1 phase using proteomic methods in B104-1-1 cells

Keywords: AMD; actinomycin D; Hsp; heat shock protein; hTM; human tropomyosin; MEK; MAP kinase kinase; Actinomycin; Proteomics; Cell cycle; MEKK3; Hsp70;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Nuclear phospholipase C-β1b activation during G2/M and late G1 phase in nocodazole-synchronized HL-60 cells

Keywords: PLC; phospholipase C; PtdIns(4,5)P2; phosphatidylinositol 4,5-bisphosphate; DAG; diacylglycerol; Ins(1,4,5)P3; inositol(1,4,5)P3; PKC; protein kinase C; PI3K; phosphatidylinositol 3-kinase; MAPK; mitogen-activated protein kinase; MEK; MAP kinase kinase; P

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

MAPK signalling pathways as molecular targets for anti-inflammatory therapy-from molecular mechanisms to therapeutic benefits

Keywords: ARE; AU-rich element; ASK; Apoptosis Signal regulating Kinase; ATF-2; Activating Transcription Factor 2; CRE; Cyclic AMP Responsive Element; ERK; Extracellular signal regulated kinase; iNOS; inducible Nitric Oxide Synthase; JNK; c-Jun N-terminal Kinase; L

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

N-methyl-d-aspartate (NMDA) and the regulation of mitogen-activated protein kinase (MAPK) signaling pathways: A revolving neurochemical axis for therapeutic intervention?

Keywords: AA; arachidonic acid; AIDS; acquired immunodeficiency syndrome; ALS; amyotrophic lateral sclerosis; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; APV; 2-amino-5-phosphonovalerate; 2-AP5; 2-amino-5-phosphonopentanoic acid; ATF; activating tr

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2005 سفارش ترجمه

Hepatocyte growth factor, its receptor, and their potential value in cancer therapies

Keywords: Abl; Abelson murine leukemia viral oncogene; AGTR; angiotensin II receptor; Arf; Archaeal Rieske-type ferredoxin; Arp; actin-related protein; BCL2; B-cell CLL/lymphoma 2; BID; BH3 interacting domain death agonist; cMET; receptor for hepatocyte growth fact

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2005 سفارش ترجمه