Pervanadate induces Mammalian Ste20 Kinase 3 (MST3) tyrosine phosphorylation but not activation

The Mammalian Ste20 Kinase 3 (MST3) undergoes tyrosine phosphorylation. The proline-rich motif of MST3 may position it close to the oncoprotein Src Homology 3 (SH3) domains of adaptor proteins. The unusual tyrosine-phosphorylated MST3 may create a docking site for downstream molecules, resulting in MST3 involvement in various signals.145