Keywords: کلیه جنینی انسان 293; Aβ1-42; 42-amino acid-long Aβ peptide; AD; Alzheimer's disease; ADAPT; Alzheimer's Disease Anti-Inflammatory Prevention Trial; ADAS-Cog; Alzheimer's Disease Assessment Scale-Cognitive Subscale; ADCS-ADL; Alzheimer's Disease Cooperative Study Activ
مقالات ISI کلیه جنینی انسان 293 (ترجمه نشده)
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Keywords: کلیه جنینی انسان 293; Skin; TGFβ; Inflammation; Extracellular matrix; Therapy; ACE; angiotensin-converting enzyme; ACE2; angiotensin-converting enzyme 2; AT1; angiotensin II receptor type 1; ADAM; a disintegrin and metalloproteinase family sheddase; AT2; angiotensin II recept
Keywords: کلیه جنینی انسان 293; CKD; chronic kidney disease; NSAIDs; non-steroidal anti-inflammatory drugs; IS; indoxyl sulfate; CVD; cardiovascular diseases; OAT; organic anion transporters; CHO; Chinese hamster ovary; HEK 293; human embryonic kidney 293; MDCKII; Madin-Darby canine kid
Keywords: کلیه جنینی انسان 293; Rhein; Rhein acyl glucuronide; Methotrexate; Organic anion transporter; Drug-drug interaction; AUC; area under the plasma time-concentration curve; ES; estrone sulfate; HBSS; Hank's balanced salt solution; HEK293; human embryonic kidney 293; IS; internal
Keywords: کلیه جنینی انسان 293; MOPr; μ-opioid receptor; GPCR; G protein-coupled receptor; TM; transmembrane domain; BRET; bioluminescence resonance energy transfer; MD; molecular dynamics; HEK 293; human embryonic kidney 293; Rluc; renilla luciferase; GFP; green fluorescent protein; Y
Keywords: کلیه جنینی انسان 293; Essential tremor; Brain; Genetics; Human population; Mouse models; Pathophysiology; ABA; Allen brain atlas; AβPPswe/PS1ÎE9; amyloid-β protein precursor and presenilin-1; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ATP; adenosine tri-ph
Keywords: کلیه جنینی انسان 293; ACTH; adrenocorticotropic hormone; BT; 2-sec-butyl dihydrothiazole; CAII; carbonic anhydrase II; CO2; carbon dioxide; CS2; carbon disulfide; cVA; 11-cis-vaccenyl acetate; DB; dehydro-exo-brevicomin; GC-D; guanylyl cyclase D; ELG; extraorbital lacrimal gla
Identification of biologically active δ-lactone eicosanoids as paraoxonase substrates
Keywords: کلیه جنینی انسان 293; Eicosanoid; Esterase; Lactone; Isoprostanes; Paraoxonase; AEBSF; 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride; cyclo-EC; cyclo-epoxycyclopentenone; 5,6-DHTL; 5,6-dihydroxy-eicosatrienoic acid lactone; EC; epoxycyclopentenone; 5,6-EET; 5,6-epoxye
The longevity gene INDY (I'm Not Dead Yet) in metabolic control: Potential as pharmacological target
Keywords: کلیه جنینی انسان 293; Aak2; 5â²AMP-activated protein kinase catalytic subunit alpha-2; ACC; acetyl CoA carboxylase; Acly; ATP citrate lyase; Adipo-IR; adipose tissue insulin resistance index; ADME; absorption, distribution, metabolism, excretion; AGA; appropriate-for-gestatio
Structural and functional analysis of two novel somatostatin receptors identified from topmouth culter (Erythroculter ilishaeformis)
Keywords: کلیه جنینی انسان 293; HEK293; Human Embryonic Kidney 293; SSTRs; somatostatin receptors; mRNAs; messenger-ribonucleic acid; SS; Somatostatin; MC-LR; microcystin-LR; E2; 17β-estradiol; MCs; microcystins; DMSO; dimethyl sulfoxide; MS-222; methanesulfonate-222; cDNA; complementa
The ciliary protein Rpgrip1l in development and disease
Keywords: کلیه جنینی انسان 293; BB; Basal body; Bbs; Bardet-Biedl syndrome; C. elegans; Caenorhabditis elegans; CC; Coiled-Coil; Cep290; Centrosomal Protein 290; COACH; Cerebellar Vermis Aplasia Oligophrenia Congenital Ataxia Coloboma Hepatic Fibrosis; CRD; Cone Rod Dystrophy; Cux1; Cut
The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques
Keywords: کلیه جنینی انسان 293; 17,18-Epoxyeicosatetraenoic acid; G protein-coupled receptor 40; Ï3 fatty acid; contact hypersensitivity; dermatitis; neutrophil; ALA; α-Linolenic acid; APC; Allophycocyanin; Chi3l3; Chitinase 3-like 3; CYP; Cytochrome P450; DAPI; 4â²-6-Diamidino-2
The efficacy of Dynorphin fragments at the κ, μ and δ opioid receptor in transfected HEK cells and in an animal model of unilateral peripheral inflammation
Keywords: کلیه جنینی انسان 293; FCA; Freund's Complete Adjuvant; KOP; κ-opioid receptor; MOP; μ-opioid receptor; DOP; δ-opioid receptor; HEK; human embryonic kidney 293; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; BSA; bovine serum albumin; Dynorphin; cAMP; Opioid re
Osmotic and heat stress-dependent regulation of MLK4β and MLK3 by the CHIP E3 ligase in ovarian cancer cells
Keywords: کلیه جنینی انسان 293; MLK3; Mixed Lineage Kinase 3; MLK4; Mixed Lineage Kinase 4; MAPK; mitogen-activated protein kinase; MAP3K; MAPK kinase kinase; MAP2K; MAPK kinase; JNK; c-Jun N-terminal kinase; siRNA; short interfering RNA; ERK; extracellular signal-regulated kinase; HEK2
Novel signaling of dynorphin at κ-opioid receptor/bradykinin B2 receptor heterodimers
Keywords: کلیه جنینی انسان 293; AC; adenylyl cyclase; B1R; bradykinin B1 receptor; B2R; bradykinin B2 receptor; BK; bradykinin; BRET; bioluminescence resonance energy transfer; CFP; cyan fluorescent protein; CNS; central nervous system; CRE; cAMP-response element; CREB; cAMP-response el
Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma
Keywords: کلیه جنینی انسان 293; Regulated Cell Death; Antitumor Immunity; HMGB1; ATP; AURKA; aurora kinase A; DAMPs; damage-associated molecular patterns; GSK3β; glycogen synthase kinase 3 beta; HEK293; human embryonic kidney 293; HPDE; human pancreatic duct epithelial cell; ICD; immun
Exploring the potential of genome editing CRISPR-Cas9 technology
Keywords: کلیه جنینی انسان 293; Cas; CRISPR-associated proteins; cccDNA; covalently closed circular DNA; CCR5; C-C chemokine receptor type 5; CHO; Chinese hamster ovary; CRISPRs; clustered regularly interspaced short palindromic repeats; CRISPRa; CRISPR activation; CRISPRi; CRISPR inter
Pervanadate induces Mammalian Ste20 Kinase 3 (MST3) tyrosine phosphorylation but not activation
Keywords: کلیه جنینی انسان 293; Cys; cysteine; DMEM; Dulbecco's modified Eagle's medium; EGFR; epidermal growth factor receptor; GPCR; G protein-coupled receptor; HEK 293; human embryonic kidney 293; HPK1; hematopoietic progenitor kinase 1; MST; mammalian Ste20 kinase; MAP4K; MAP kinase
Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer
Keywords: کلیه جنینی انسان 293; Epigenetic inhibitors; Prostate cancer; Kidney cells; Nephrotoxicity; 5-Aza; 5-aza-2ʹ-deoxycytidine; CBZ; carbamazapine; CDK; cyclin-dependent kinase; CDKN1a; cyclin-dependent kinase inhibitor 1a; CFZ; carfilzomib; ChIP; chromatin immunoprecipitation; DM
In vitro pharmacological evaluation of multitarget agents for thromboxane prostanoid receptor antagonism and COX-2 inhibition
Keywords: کلیه جنینی انسان 293; AA; arachidonic acid; CV; cardiovascular; COX; cyclooxygenase coxibs; COX-2; selective inhibitors; DMEM; Dulbecco's modified eagle's medium; EIA; enzyme immunoassay; IP; inositol phosphate; HEK293; human embryonic kidney 293; NSAID; nonsteroidal anti-
Identification of NF-κB inhibitors following Shenfu injection and bioactivity-integrated UPLC/Q-TOF-MS and screening for related anti-inflammatory targets in vitro and in silico
Keywords: کلیه جنینی انسان 293; BMC; Benzoyl-mesaconine; CAD; Coronary artery disease; CHD; Coronary heart disease; DEX; Dexamethasone; DMEM; Dulbecco's modified Eagle's Medium; ELISA; Enzyme-linked immunosorbent assay; ESI; Electrospray ionization; FBS; Fetal bovine serum; FUZ; Fuzil
SGIP1 alters internalization and modulates signaling of activated cannabinoid receptor 1 in a biased manner
Keywords: کلیه جنینی انسان 293; Seven transmembrane receptors; G-protein coupled receptors; Cannabinoid receptor 1; Protein-protein interactions; Bias signaling; Receptor endocytosis; SGIP1; src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1; CC
Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis
Keywords: کلیه جنینی انسان 293; NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; Nrf2; nuclear factor erythroid 2-related factor 2; Keap1; Kelch-like ECH associated protein 1; TUNEL; terminal deoxynucleotidyl transferase dUTP nick end labeling; MTT; 3-(4,5-di
Epoxyeicosatrienoic acids act through TRPV4-TRPC1-KCa1.1 complex to induce smooth muscle membrane hyperpolarization and relaxation in human internal mammary arteries
Keywords: کلیه جنینی انسان 293; LIMAs; human left internal mammary arteries; EETs; epoxyeicosatrienoic acids; 11,12-EET; 11,12-epoxyeicosatrienoic acid; KCa1.1; large conductance Ca2Â +-activated K+ channels; TRPV4; vanilloid transient receptor potential channel 4; TRPC1; canonical tran
The role of exosomes and “exosomal shuttle microRNA” in tumorigenesis and drug resistance
Keywords: کلیه جنینی انسان 293; TD-exosomes; tumor-derived-exosomes; MVBs; multivesicular bodies; CEA; carcinoembryonic antigen; PTEN; phosphatase and tensin homologue; GSK; glycogen synthase kinase; NK; natural killer; MDR; multi-drug resistance; ABC; ATP-binding cassette; MAC; membran
Calcineurin B homologous protein 3 negatively regulates cardiomyocyte hypertrophy via inhibition of glycogen synthase kinase 3 phosphorylation
Keywords: کلیه جنینی انسان 293; Akt; protein kinase B; ANP; atrial natriuretic peptide; CaMKII; Ca2Â +/calmodulin-dependent protein kinase II; CHP3; calcineurin B homologous protein 3; DAPI; 4â²,6-diamidino-2-phenylindole dihydrochloride; DMEM; Dulbecco's modified Eagle's medium; FBS;
Role of cystic fibrosis transmembrane conductance regulator-associated ligand (CAL) in regulating the trafficking and signaling of corticotropin-releasing factor receptor 1
Keywords: کلیه جنینی انسان 293; 5HT2AR; Serotonin 2A receptor; ACTH; Adrenocorticotropin hormone; ANOVA; Analysis of variance; CAL; CFTR-associated ligand; cAMP; Cyclic adenosine monophosphate; CFTR; Cystic Fibrosis Transmembrane Conductance Regulator; CNS; Central nervous system; CRF;
Ca2Â +-dependent repair of pneumolysin pores: A new paradigm for host cellular defense against bacterial pore-forming toxins
Keywords: کلیه جنینی انسان 293; PLY; pneumolysin; SLO; streptolysin O; TLR; toll-like receptor; PKC; protein kinase C α; HEK; human embryonic kidney 293; CCh; carbachol; AEC; airway epithelial cells; HBE; human bronchial epithelial 16HBE14o-; Anx; annexin; Plasma membrane; Calcium; Ann
PDZK1/NHERF3 Differentially Regulates Corticotropin-releasing Factor Receptor 1 and Serotonin 2A Receptor Signaling and Endocytosis
Keywords: کلیه جنینی انسان 293; ANOVA; analysis of variance; β 1AR; β 1-adrenergic receptor; β2AR; β2-adrenergic receptor; CRF; corticotropin-releasing factor; CRFR1; CRF receptor 1; CRFR2; CRF receptor 2; ERK1/2; extracellular signal-regulated kinase; GKAP; guanylate kinase-associa
Bioactivity-integrated UPLC/Q-TOF-MS of Danhong injection to identify NF-κB inhibitors and anti-inflammatory targets based on endothelial cell culture and network pharmacology
Keywords: کلیه جنینی انسان 293; Akt; protein kinase B; ANAVO; analysis of variance; Bax; Bcl-2 associated X protein; Bcl-2; B-cell lymphoma-2; BCR; B cells receptors; CA; caffeic acid; CAD; coronary artery disease; CHM; Chinese herbal medicines; DEX; dexamethasone; DHI; Danhong injectio
Comparative evaluation of different cultivars of Flos Chrysanthemi by an anti-inflammatory-based NF-κB reporter gene assay coupled to UPLC-Q/TOF MS with PCA and ANN
Keywords: کلیه جنینی انسان 293; TCM; traditional Chinese medicine; UPLC-Q/TOF MS; ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry; BPI; base peak intensity; PCA; principal component analysis; ANN; artificial neural network; FC; Flos Chrysanthemi; BJ;
Protein kinase C enhances human sodium channel hNav1.7 resurgent currents via a serine residue in the domain III-IV linker
Keywords: کلیه جنینی انسان 293; PEPD; paroxysmal extreme pain disorder; VGSC; voltage-gated sodium channels; Bis I; bisindolylmaleimide I; PMA; phorbol 12-myristate 13-acetate; Che; chelerythrine; AP; action potential; DRG; dorsal root ganglion; PKC; protein kinase C; HEK293; human embr
SIRT4 inhibits cigarette smoke extracts-induced mononuclear cell adhesion to human pulmonary microvascular endothelial cells via regulating NF-κB activity
Keywords: کلیه جنینی انسان 293; COPD; chronic obstructive pulmonary disease; CS; cigarette smoking; CSE; cigarette smoking extracts; VCAM-1; vascular cell adhesion molecule-1; HPMECs; human pulmonary microvascular endothelial cells; FBS; fetal bovine serum; Ad-SIRT4; adenoviral SIRT4; H
A truncating SCN5A mutation combined with genetic variability causes sick sinus syndrome and early atrial fibrillation
Keywords: کلیه جنینی انسان 293; AF; atrial fibrillation; AP; action potential; BrS; Brugada syndrome; GFP; green fluorescent protein; HEK293; human embryonic kidney 293; HP; holding potential; INa; inward sodium current; LQTS; long QT syndrome; SNP; single nucleotide polymorphism; SSS;
Aquaporin-facilitated transmembrane diffusion of hydrogen peroxide
Keywords: کلیه جنینی انسان 293; AQP; aquaporin; ASMC; aortic smooth muscle cells; CM-H2DCFDA; (5-(and-6)-chloromethyl-2,7-dichlorodihydrofluorescein diacetate acetyl ester; EGF; epidermal growth factor; GLP; glycerol facilitator-like protein; HDCFDA; 2â²7â²-dichlorodihydrofluorescein
A KCNQ1 mutation contributes to the concealed type 1 long QT phenotype by limiting the Kv7.1 channel conformational changes associated with protein kinase A phosphorylation
Keywords: کلیه جنینی انسان 293; AKAP9; A-kinase anchoring protein 9 (Yotiao); AP; action potential; APD90; steady-state action potential duration at 90% repolarization; ECG; electrocardiogram/electrocardiographic; HEK293; human embryonic kidney 293; IKs; slowly activating delayed rectif
Insulin receptor substrate-1 (IRS-1) forms a ribonucleoprotein complex associated with polysomes
Keywords: کلیه جنینی انسان 293; IRSs; insulin receptor substrates; IGFs; insulin-like growth factors; PABPC1; poly(A) binding protein cytoplasmic 1; MALDI-TOF-MS; matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry; BN-PAGE; blue native-polyacrylamide gel elec
Chorein, the protein responsible for chorea-acanthocytosis, interacts with β-adducin and β-actin
Keywords: کلیه جنینی انسان 293; ChAc; chorea-acanthocytosis; VPS13A; vacuolar protein sorting 13 homolog A; HEK293; human embryonic kidney 293; TtVPS13A; Tetrahymena thermophila VPS13A; MEME; Minimum Essential Medium Eagle; FBS; fetal bovine serum; CBB; Coomassie Brilliant Blue; MALDI-T
Modulation of low-voltage-activated T-type Ca2Â + channels
Keywords: کلیه جنینی انسان 293; LVA; low-voltage-activated; HVA; high-voltage-activated; T-type channels; T-type Ca2Â + channels; cAMP; cyclic adenosine monophosphate; PKA; protein kinase A; PKC; protein kinase C; PKG; protein kinase G; PTK; protein tyrosine kinase; HEK293; human embryo
Accessory subunits alter the temperature sensitivity of Kv4.3 channel complexes
Keywords: کلیه جنینی انسان 293; AP; action potential; APD; action potential duration; AUC; area under the curve; CHO; Chinese hamster ovary; DPPL; dipeptidyl aminopeptidase-like protein; DPP6S/DPP6L; short/long isoform of dipeptidyl aminopeptidase-like protein 6; ÎG0; change in Gibbs f
Reduction of nuclear encoded enzymes of mitochondrial energy metabolism in cells devoid of mitochondrial DNA
Keywords: کلیه جنینی انسان 293; ATP; adenosine-tri-phosphate; BN PAGE; Blue Native polyacrylamide gel electrophoresis; CS; citrate synthase; DAPI; diamidino-2-phenylindole; DMEM; Dulbecco's modified Eagles's medium; EDTA; ethylene-diamine-tetra-acetic acid; EtBr; ethidium bromide; H
Crystal structure of a conformation-dependent rabbit IgG Fab specific for amyloid prefibrillar oligomers
Keywords: کلیه جنینی انسان 293; Fab; Antigen-binding fragment; PDB; Protein Data Bank; AD; Alzheimer's disease; M204; Monoclonal antibody 204; PFOs; Prefibrillar oligomers; Aβ; Amyloid beta peptide; FOs; Fibrillar oligomers; APFs; Annular protofibrils; IgG; Immunoglobulin G; (HEK293) c
A novel role for P2X7 receptor signalling in the survival of mouse embryonic stem cells
Keywords: کلیه جنینی انسان 293; ES; embryonic stem; m; mouse; HEK293; human embryonic kidney 293; Ion channel; ATP; Stem cell; Receptor; Survival; P2X receptor;
Ensemble and single particle fluorimetric techniques in concerted action to study the diffusion and aggregation of the glycine receptor α3 isoforms in the cell plasma membrane
Keywords: کلیه جنینی انسان 293; ãr2ã; mean square displacement; Ï0; laser beam radius at 1/e2 of its maximum intensity; CLSM; confocal laser scanning microscope; Dâ²; time-dependent diffusion coefficient; D1-3; diffusion coefficient derived from the time lags 1 to 3; DC; dichroi
Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein
Keywords: کلیه جنینی انسان 293; 17-N-Allylamino-17-demethoxygeldanamycin (17-AAG):GABAA receptor-protein-like 1 (GABARAPL1); Glandular epithelial cell 1 (GEC1); Heat shock protein 90 (HSP90); Michigan cancer foundation-7 (MCF-7); Proteasome inhibitors; 17-AAG; 17-N-Allylamino-17-demetho
Proteolytic cleavage of the disease-related lysosomal membrane glycoprotein CLN7
Keywords: کلیه جنینی انسان 293; BFA; brefeldin A; CHX; cycloheximide; Ctsb; cathepsin B; Ctsl; cathepsin L; DMEM; Dulbecco's minimal essential medium; endo H; endoglycosidase H; ER; endoplasmic reticulum; GFP; green fluorescent protein; HEK293; human embryonic kidney 293; HGSNAT; hepari
The third intracellular loop of D1 and D5 dopaminergic receptors dictates their subtype-specific PKC-induced sensitization and desensitization in a receptor conformation-dependent manner
Keywords: کلیه جنینی انسان 293; AC; adenylyl cyclase; Bmax; maximal binding capacity; BSA; bovine serum albumin; β2-AR; β2-adrenergic receptor; CA; [3H]-cAMP formed; CT; cytoplasmic tail; DA; dopamine; DMSO; dimethyl sulfoxide; EL3; third extracellular loop; EC50; effective concentrat
Signalling pathway of goldfish melanin-concentrating hormone receptors 1 and 2
Keywords: کلیه جنینی انسان 293; cAMP; cyclic AMP; ERK1/2; extracellular signal-related kinase 1/2; gfMCHR; goldfish melanin-concentrating hormone receptor; HEK293; human embryonic kidney 293; MCH; melanin-concentrating hormone; MCHR1; MCH-1 receptor; MCHR2; MCH-2 receptor; PTX; pertussi
Vibrio vulnificus IlpA induces MAPK-mediated cytokine production via TLR1/2 activation in THP-1 cells, a human monocytic cell line
Keywords: کلیه جنینی انسان 293; LPS; lipopolysaccharide; TNF-α; tumor necrosis factor-α; IlpA; immunogenic lipoprotein A; rIlpA; recombinant IlpA; mrIlpA; mutant rIlpA protein; IL; interleukin; TLR; toll-like receptor; HEK 293; human embryonic kidney 293; PBS; phosphate-buffered salin
KChIP1 modulation of Kv4.3-mediated A-type K+ currents and repetitive firing in hippocampal interneurons
Keywords: کلیه جنینی انسان 293; CA1 hippocampus; inhibitory neurons; excitability; K+ channels; accessory proteins; ACSF; artificial cerebrospinal fluid; AHP; afterhyperpolarization; DMEM; Dulbelcco's modified Eagle's medium; DPPL; dipeptidyl-peptidase-like protein; ERK; extracellular s