Elucidating binding modes of zuonin A enantiomers to JNK1 via in silico methods
Keywords: MAPK; Kinase; Non-ATP competitive inhibitor; Docking; Molecular dynamics; JNK; MAPK
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The role of ERK1/2 in the regulation of proliferation and differentiation of astrocytes in developing brain
Keywords: MAPK; ERK1/2; MAPK; Astrocyte development; Glioma
EETs mediate cardioprotection of salvianolic acids through MAPK signaling pathway
Keywords: MAPK; Salvianolic acids; Acute myocardial infarction; EETs/sEH; MAPK
TRPM7 mediates breast cancer cell migration and invasion through the MAPK pathway
Keywords: MAPK; TRPM7; Breast cancer; Invasion; Src; MAPK
The Hordeum vulgare signalling protein MAP kinase 4 is a regulator of biotic and abiotic stress responses
Keywords: MAPK; GC–MS, gas chromatography–mass spectrometry; JA, jasmonic acid; MAP kinase, mitogen activated protein kinase; PAMP, pathogen associated molecular pattern; SA, salicylic acidBarley; Cereal; MAPK; Magnaporthe grisea; Salt stress
Leptin induces cell invasion and the upregulation of matrilysin in human colon cancer cells
Keywords: MAPK; Akt; human colon cancer cells; invasion; leptin; MAPK; matrilysin; siRNA;
Anti-inflammatory effects of linalool in RAW 264.7 macrophages and lipopolysaccharide-induced lung injury model
Keywords: MAPK; Linalool; Lipopolysaccharide; NF-κB; MAPK; Cytokines; Acute lung injury; Anti-inflammatory
Suppressive effects of levobupivacaine on endotoxin-induced microglial activation
Keywords: MAPK; Microglia; LPS; NF-κB; MAPK; Chemokine; Cytokine
Interleukin-33 mediates formalin-induced inflammatory pain in mice
Keywords: MAPK; CNS; central nervous system; ERK; extracellular-signal-regulated kinases; IL-33; interleukin-33; MAPK; mitogen-activated protein kinases; rIL; recombinant IL-33; SEM; standard error; SPSS; Statistical Package for the Social Sciences; PBS; phosphate buffer
Differential gene expressions of the MAPK signaling pathway in enterovirus 71-infected rhabdomyosarcoma cells
Keywords: MAPK; Enterovirus 71; Rhabdomyosarcoma cells; MAPK; PCR array
Single prolonged stress enhances hippocampal glucocorticoid receptor and phosphorylated protein kinase B levels
Keywords: MAPK; PTSD; posttraumatic stress disorder; SPS; single prolonged stress; EPM; elevated plus maze; OF; open field; GR; glucocorticoid receptor; Akt; protein kinase B; pAkt; phosphorylated Akt; PI3K; phosphoinositide 3-kinase; mTOR; mammalian target of Rapamycin;
A vitamin D3 analog augmented interleukin-8 production by human monocytic cells in response to various microbe-related synthetic ligands, especially NOD2 agonistic muramyldipeptide
Keywords: MAPK; IL-8; MAPK; Muramyldipeptide; NF-κB; NOD2; Vitamin D3 analog
Two initiation sites of early detection of colon cancer revealed by localization of pERK1/2 in the nuclei or in aggregates at the perinuclear region of the tumor cells
Keywords: MAPK; Colon cancer; MAPK; pERK1/2; Cancer stem cells; p53; KRAS; Epiregulin
Targeting apoptosis pathways in cancer by Chinese medicine
Keywords: MAPK; Cancer; Apoptosis; ROS; DNA damage; NF-κB; MAPK; Drug
ELK1 Transcription Factor Linked to Dysregulated Striatal Mu Opioid Receptor Signaling Network and OPRM1 Polymorphism in Human Heroin Abusers
Keywords: MAPK; Addiction; MAPK; opioid; rat; self-administration; transcriptome
Postmortem and ex vivo carbon monoxide ventilation reduces injury in rat lungs transplanted from non-heart-beating donors
Keywords: MAPK; cGMP; cyclic guanosine monophosphate; CO; carbon monoxide; DCD; donation-after-cardiac-death donor; ERK; extracellular signal-regulated kinase; EVLP; ex vivo lung perfusion; HO; heme oxidase; IL; interleukin; IκBα; nuclear factor of kappa light polypep
Synergistic inhibition of thyroid cancer by suppressing MAPK/PI3K/AKT pathways
Keywords: MAPK; Thyroid cancer; AZD6244; GDC0941; Synergism; MAPK; PI3K/AKT
Arsenic induces the expressions of angiogenesis-related factors through PI3K and MAPK pathways in SV-HUC-1 human uroepithelial cells
Keywords: MAPK; Arsenite; HIF-1α; COX-2; VEGF; MAPK; PI3K/AKT
Chlorogenic acid, a dietary polyphenol, protects acetaminophen-induced liver injury and its mechanism
Keywords: MAPK; Chlorogenic acid; Acetaminophen; Caspase; GSH; Trx; MAPK
Protective effect of esculentoside A on lipopolysaccharide-induced acute lung injury in mice
Keywords: MAPK; Esculentoside A; Acute lung injury; LPS; MAPK; IκBa
Replacement treatment with microRNA-143 and -145 induces synergistic inhibition of the growth of human bladder cancer cells by regulating PI3K/Akt and MAPK signaling pathways
Keywords: MAPK; microRNA-143; microRNA-145; Bladder cancer; PI3K/Akt; MAPK
Angelicin regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways
Keywords: MAPK; Angelicin; Lipopolysaccharide; Cytokines; NF-κB; MAPK
Crocetin, a carotenoid derivative, inhibits retinal ischemic damage in mice
Keywords: MAPK; Crocetin; MAPK; Oxidative stress; Retinal ischemia
Dietary unsaponifiable fraction from extra virgin olive oil supplementation attenuates acute ulcerative colitis in mice
Keywords: MAPK; Unsaponifiable fraction; Extra virgin olive oil; iNOS; COX-2; MAPK; IκBα
BML-111 attenuates hemorrhagic shock-induced acute lung injury through inhibiting activation of mitogen-activated protein kinase pathway in rats
Keywords: MAPK; Hemorrhagic shock; Acute lung injury; Inflammation; BML-111; MAPK
Pituitary tumor transforming gene and insulin-like growth factor 1 receptor expression and immunohistochemical measurement of Ki-67 as potential prognostic markers of pituitary tumors aggressiveness
Keywords: MAPK; PA; pituitary adenomas; PTTG; pituitary tumor transforming gene; IGF1R; insulin-like growth factor 1 receptor; RT-PCR; real time polymerase chain reaction; PI3K/Akt; phosphoinositide 3-kinase/Akt pathway; MAPK; mitogen-activated protein kinases; MRI; magn
Linoleic acid increases adhesion, chemotaxis, granule release, intracellular calcium mobilisation, MAPK phosphorylation and gene expression in bovine neutrophils
Keywords: MAPK; MMP-9, metalloproteinase-9; MAPK, mitogen-activating protein kinase; COX-2, cyclooxygenase-2Neutrophils; Linoleic acid; MMP-9; CD11b; MAPK
Participation of cAMP-dependent protein kinase and MAP kinase pathways during Anabas testudineus oocyte maturation
Keywords: MAPK; cAMP dependent protein kinase; H89; PKI; Oocyte maturation; MAPK; Anabas testudineus
Synthetic lethal interaction between PI3K/Akt/mTOR and Ras/MEK/ERK pathway inhibition in rhabdomyosarcoma
Keywords: MAPK; Apoptosis; Rhabdomyosarcoma; PI3K; MAPK
Remote Ischemic Preconditioning for Coronary Artery Bypass Graft Operations
Keywords: MAPK; 17; AAR; area at risk; ATP; adenosine triphosphate; AUC; area under the curve; BNP; brain natriuretic peptide; CABG; coronary artery bypass graft; CGRP; calcitonin gene-related peptide; CK-MB; creatine kinase-MB; I; induction; I/R; ischemia-reperfusion; i
Anti-tumorigenic action of 2-[piperidinoethoxyphenyl]-3-[4-hydroxyphenyl]-2H-benzo(b)pyran: Evidence for involvement of GPR30/EGFR signaling pathway
Keywords: MAPK; Endometrial cancer; Benzopyrans; GPR30; EGFR signaling; MAPK; Ishikawa xenograft model;
Riccardin D-26, a synthesized macrocyclic bisbibenzyl compound, inhibits human oral squamous carcinoma cells KB and KB/VCR: In vitro and in vivo studies
Keywords: MAPK; Synthesized macrocyclic bisbibenzyl compound; KB/VCR; MDR; Mitochondria-mediated intrinsic apoptosis pathway; MAPK; PI3K/Akt
RKIP regulates MAP kinase signaling in cells with defective B-Raf activity
Keywords: MAPK; RKIP; Raf-1; B-Raf; MAPK
Effects of recombinant trout leptin in superoxide production and NF-κB/MAPK phosphorylation in blood leukocytes
Keywords: MAPK; CD4; cluster of differentiation 4; CD8; cluster of differentiation 8; ERK; extracellular-signal-regulated kinase; ERK1/2; extracellular signal-regulated kinase 1/2; IL-6; interleukin 6; IL-12; interleukin 12; JNK; c-Jun N-terminal kinase; NF-κB; nuclear
Yuwen02f1 suppresses LPS-induced endotoxemia and adjuvant-induced arthritis primarily through blockade of ROS formation, NFkB and MAPK activation
Keywords: MAPK; Diphenylpyrazole; ROS; NFκB; MAPK; Inflammatory animal
CB1 cannabinoid receptors promote maximal FAK catalytic activity by stimulating cooperative signaling between receptor tyrosine kinases and integrins in neuronal cells
Keywords: MAPK; 2-AG; 2-arachidonoylglycerol; BSA; bovine serum albumin; CB1; CB1 cannabinoid receptor; Csk; C-terminal Src kinase; DAGL; diacylglycerol lipase; DTT; dithiothreitol; ECM; extracellular matrix; ERK1/2; extracellular signal-regulated kinases 1 and 2; EGFR;
dNF-YB plays dual roles in cell death and cell differentiation during Drosophila eye development
Keywords: MAPK; NF-Y; Nuclear transcription factor Y; HFM; histone-fold motif; dNF-YB; Drosophila NF-YB; MAPK; mitogen-activated protein kinase; debcl; death executioner Bcl-2; HSC; hematopoietic stem cell; SMW; the second mitotic wave; BrdU; Bromodeoxyuridine; Pros; Pro
Thioredoxin-mimetic peptides (TXM) reverse auranofin induced apoptosis and restore insulin secretion in insulinoma cells
Keywords: MAPK; Thioredoxin; Oxidative stress; Diabetes; Insulin secretion; MAPK; Apoptosis; Molecular dynamics; ASK1
Progastrin-Induced Secretion of Insulin-Like Growth Factor 2 From Colonic Myofibroblasts Stimulates Colonic Epithelial Proliferation in Mice
Keywords: MAPK; Mouse Model; Colon Cancer; PKC; PI3K; CCK-2R; cholecystokinin-2 receptor; CgA; chromogranin A; DAPI; 4â²,6-diamidino-2-phenylindole; DMSO; dimethyl sulfoxide; FCS; fetal calf serum; G-Gly; glycine-extended gastrin; G-17; gastrin-17; hGAS; high circulatin
MicroRNA-137, an HMGA1 Target, Suppresses Colorectal Cancer Cell Invasion and Metastasis in Mice by Directly Targeting FMNL2
Keywords: MAPK; Mouse Model; Gene Expression; Tumor Suppressor Activity; Signaling Pathway; Akt; protein kinase B; CRC; colorectal cancer; ERK; extracellular signal-regulated kinase; FMNL2; formin-like 2; HMGA; high-mobility group AT-hook; MAPK; mitogen-activated prote
Pro-Angiogenic Activity of TLRs and NLRs: A Novel Link Between Gut Microbiota and Intestinal Angiogenesis
Keywords: MAPK; Angiogenesis; IBD; TLR; NLR; bFGF; basic fibroblast growth factor; DMEM; Dulbecco's minimal essential medium; FAK; focal adhesion kinase; FBS; fetal bovine serum; GFP; green fluorescent protein; HIF; human intestinal fibroblast; HIMEC; human intestinal mi
Loss of Protein Tyrosine Phosphatase Nonreceptor Type 22 Regulates Interferon-γ-Induced Signaling in Human Monocytes
Keywords: MAPK; SOCS1; ICAM1; MCP1; Th17; CD; Crohn's disease; ERK; extracellular signal-regulated kinase; IBD; inflammatory bowel disease; ICAM; intracellular adhesion molecule; IFN-γ; interferon γ; IκB; inhibitor of κB; IL; interleukin; Jak; Janus kinase; JNK; c-
Endogenous opiates and behavior: 2012
Keywords: MAPK; Ach; acetylcholine; ACTH; adrenocorticotrophic hormone; ANG; angiotensin; ATP; adenosine triphosphate; BAM22; bovine adrenal medulla 22; BDNF; brain-derived neurotrophic factor; BEND; beta-endorphin; BFNA; beta-funaltrexamine; BNST; bed nucleus of the str
Neuronal and intracellular signaling pathways mediating GLP-1 energy balance and glycemic effects
Keywords: MAPK; Leptin; GLP-1; NTS; Hypothalamus; Pancreas; Insulin; PKA; AMPK; MAPK; ERK; CREB; Food intake; Obesity;
Collagen I confers gamma radiation resistance
Keywords: MAPK; Collagen; Gamma radiation; MAPK; Thermoluminescent dosimeters
Involvement of the MAPK and RhoA/ROCK pathways in PGE2-mediated CCR7-dependent monocyte migration
Keywords: MAPK; Monocytes; CCR7; Migration; MAPK; RhoA/ROCK
Hyperosmotic Stress Induces Cell Death in an Odontoblast-lineage Cell Line
Keywords: MAPK; Cell death; hyperosmotic stress; MAPK; odontoblast cells; sucrose
Vitronectin improves cell survival after radiation injury in human umbilical vein endothelial cells
Keywords: MAPK; Vitronectin; Integrin; p21; Radiation; MAPK
Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics
Keywords: MAPK; ASK1; apoptosis signal-regulating kinase 1; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; BAX; Bcl2 associated X protein; BAK; BCL2-antagonist/killer; CHOP; C/EBP-homologous protein; eIF2α; eukaryotic initiation factor
Identification of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4-one derivatives as inhibitors of the phosphatase SerB653 in Porphyromonas gingivalis, implicated in periodontitis
Keywords: MAPK; IC50; half-maximal inhibitory concentration; MIC; minimum inhibitory concentration; IL-8; interleukin-8; PMSF; phenylmethylsulfonyl fluoride; DMSO; dimethyl sulfoxide; MAPK; mitogen-activated protein kinase; Periodontitis; Gram-negative anaerobe; Haloacid