A role for IL-17 in induction of an inflammation at the fetomaternal interface in preterm labour
Keywords: MAPK; Amniotic fluid; Chorioamnionitis; IKK; MAPK; Preterm delivery; Th17
مقالات ISI MAPK (ترجمه نشده)
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Lysophosphatidic acid induces upregulation of Mcl-1 and protects apoptosis in a PTX-dependent manner in H19-7 cells
Keywords: MAPK; LPA; lysophosphatidic acid; NPC; neuronal progenitor cell; Mcl; myeloid cell leukemia; GSK-3; glycogen synthase kinase 3; PTX; pertussis toxin; FGF; fibroblast growth factor; S1P; sphingosine 1-phosphate; GPCR; G-protein coupled receptor; E; embryonic day
Innate immune response to H3N2 and H1N1 influenza virus infection in a human lung organ culture model
Keywords: MAPK; Influenza virus; Lung; Cytokine; Chemokine; MAPK; IP-10; MIP-1α
Characterization of a novel MK3 splice variant from murine ventricular myocardium
Keywords: MAPK; DMSO; dimethylsulfoxide; DTT; dithiothreitol; ERK; extracellular signal-related kinase; FPLC; fast protein liquid chromatography; GST; glutathione S-transferase; MAPK; mitogen-activated protein kinase; MK2; MAPK-activated protein kinase-2; MK3; MAPK-activ
Dexamethasone enhances the norepinephrine-induced ERK/MAPK intracellular pathway possibly via dysregulation of the α2-adrenergic receptor: Implications for antidepressant drug mechanism of action
Keywords: MAPK; 5-HT; serotonin; AP-1; activator protein 1; AR; adrenergic receptor; BDNF; brain derived neurotrophic factor; DEX; dexamethasone; FCS; fetal calf serum; GC; glucocorticoid; GPCR; G-protein-coupled receptor; GR; glucocorticoid receptor; GRK; G-protein rece
Oleate dose-dependently regulates palmitate metabolism and insulin signaling in C2C12 myotubes
Keywords: MAPK; Akt; protein kinase B; ANOVA; one-way analysis of variance; ASP; acid-soluble products; BSA; bovine serum albumin; C2; C2-carnitine; DAG; diacylglycerides; DGAT; diacylglycerol acyltransferase; DMEM; Dulbecco's modified Eagle's medium; FCS; Fetal calf ser
Comparative proteome profile during the early period of small-for-size liver transplantation in rats revealed the protective role of Prdx5
Keywords: MAPK; Comparative proteome; Small-for-size liver transplantation; Oxidative stress; Apoptosis; Regeneration; LDLT; living-donor liver transplantation; IRI; ischemia-reperfusion injury; SFSG; small-for-size liver graft; SFSLT; Small-for-size liver transplantat
Clinical utility of calcimimetics targeting the extracellular calcium-sensing receptor (CaSR)
Keywords: MAPK; CaSR; calcium-sensing receptor; Cao2+; extracellular calcium concentration; PTH; parathyroid hormone; NKF; National Kidney Foundation; FDA; US Food and Drug Administration; CKD; chronic kidney disease; MGluR; metabotropic glutamate receptor; GABA; gamma a
Oncogenic KRAS Desensitizes Colorectal Tumor Cells to Epidermal Growth Factor Receptor Inhibition and Activation
Keywords: MAPK; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kinase; MAPK; mitogen-activated protein kinase; MEK; MAPK/ERK kinase; PI3K; phosphatidylinositol-3-kinase;
Arsenic trioxide-mediated antiplatelet activity: pivotal role of the phospholipase Cγ2-protein kinase C-p38 MAPK cascade
Keywords: MAPK; AA; arachidonic acid; APL; acute promyelocytic leukemia; As2O3; arsenic trioxide; ATRA; all-trans-retinoic acid; ATP; adenosine triphosphate; BSA; bovine serum albumin; ECL; enhanced chemiluminescence; EDTA; ethylenediaminetetraacetic acid; DAG; diacylgly
Resin monomer-induced differential activation of MAP kinases and apoptosis in mouse macrophages and human pulp cells
Keywords: MAPK; Resin monomer; TEGDMA; MAPK; Cytokine; Apoptosis
Green tea polyphenol epigallocatechi3-gallate: Inflammation and arthritis
Keywords: MAPK; Green Tea; EGCG; Osteoarthritis; Rheumatoid arthritis; MAPK; NF-κB
Morphine tolerance attenuates the resolution of postoperative pain and enhances spinal microglial p38 and extracellular receptor kinase phosphorylation
Keywords: MAPK; chronic pain; microglial memory; MAPK; opioids; paw incision; glia; ERK; extracellular receptor kinase; GFAP; glial fibrillary acidic protein; Iba1; ionized calcium adaptor-binding protein 1; JNK; c-Jun N-terminal kinase; MAPK; mitogen activated protein k
Paired Immunoglobulin-Like Receptor B (PIR-B) Negatively Regulates Macrophage Activation in Experimental Colitis
Keywords: MAPK; Inhibitory Receptors; Macrophages; IBD; DSS; dextran sodium sulfate; eGFP; enhanced green fluorescent protein; ERK; extracellular signal-regulated kinase; Ig; immunoglobulin; IL; interleukin; ILT; immunoglobulin-like transcript; ITIM; immunoreceptor tyr
Neuroprotection of ethanol against ischemia/reperfusion-induced brain injury through decreasing c-Jun N-terminal kinase 3 (JNK3) activation by enhancing GABA release
Keywords: MAPK; ethanol; neuroprotection; brain ischemia-reperfusion; GABA; c-Jun N-terminal kinase 3 (JNK3); Akt/PKB; protein kinase B; ERK; extracellular signal-regulated kinase; Gluk2; glutamate receptor 6; GluN2A; N-methyl-d-aspartic acid receptor subunit 2A; JNK; c-
Estrogen receptor alpha and G-protein coupled receptor 30 mediate the neuroprotective effects of 17β-estradiol in novel murine hippocampal cell models
Keywords: MAPK; glutamate; immortalization; cell biology; signal transduction; hippocampus; membrane estrogen receptor; Akt; homologous enzyme sequence of viral oncogene v-akt isolated from AKR mouse spontaneous thymoma cell line and also called protein kinase B; AR; and
Allicin protects against cardiac hypertrophy and fibrosis via attenuating reactive oxygen species-dependent signaling pathways
Keywords: MAPK; Allicin; Cardiac hypertrophy; MAPK; Reactive oxygen species;
Disruption of Smad-dependent signaling for growth of GST-P-positive lesions from the early stage in a rat two-stage hepatocarcinogenesis model
Keywords: MAPK; ATF; activating transcriptional factor; DEHP; di(2-ethylhexyl) phthalate; DEN; N-diethylnitrosamine; early-stage; 6Â weeks after starting tumor promotion; FB; fenbendazole; GST-P; glutathione S-transferase placental form; late-stage; 57Â weeks after start
c-Jun N-terminal kinase (JNK) signaling: Recent advances and challenges
Keywords: MAPK; Ago; Argonaute; DELFIA; Dissociation Enhanced Lathanide Fluoro-Immuno Assay; D-JNKI-1; cell-permeable JIP1-derived JNK inhibitory peptide-1 (D-amino acids); ELISA; enzyme-linked immunosorbent assays; ERK; extracellular signal-regulated kinase (ERK); FITC;
Hepatotoxicity of di-(2-ethylhexyl)phthalate is attributed to calcium aggravation, ROS-mediated mitochondrial depolarization, and ERK/NF-κB pathway activation
Keywords: MAPK; Di-(2-ethylhexyl)phthalate; Hepatic oxidative stress; NF-κB; MAPK; Apoptosis; Free radicals;
Tissue selectivity and potential clinical applications of trenbolone (17β-hydroxyestra-4,9,11-trien-3-one): A potent anabolic steroid with reduced androgenic and estrogenic activity
Keywords: MAPK; 17 β-TBOH; trenbolone; 17 α-TBOH; epitrenbolone; 17β-E2; estradiol; AR; androgen receptor; Akt; serine/threonine-specific kinase family; ACTH; adrenocorticotropic hormone; BMD; bone mineral density; Ca2+; calcium; CSA; cross-sectional area; DHT; dihydr
Pharmacodynamic Characterization of the Efficacy Signals Due to Selective BRAF Inhibition with PLX4032 in Malignant Melanoma
Keywords: MAPK; AKT; v-akt murine thymoma viral oncogene homolog; ANOVA; analysis of variance; ATCC; American Type Culture Collection; BRAF; v-raf murine sarcoma viral oncogene homolog B1; BRAFm; BRAF mutation; CKIT; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene
Targeting the MAPK pathway in melanoma: Why some approaches succeed and other fail
Keywords: MAPK; MAPK; Melanoma; V600EB-RAF; MEK; ERK; Resistance
Deregulation of Rab5 and Rab4 proteins in p85R274A-expressing cells alters PDGFR trafficking
Keywords: MAPK; EEA1; Early endosomal autoantigen 1; FRAP; Fluorescence recovery after photobleaching; GAP; GTPase activating protein; GDI; Guanine nucleotide dissociation inhibitor; GEF; Guanine nucleotide exchange factor; MAPK; Mitogen-activated protein kinase; p85α;
Angiogenesis and Current Antiangiogenic Strategies for the Treatment of Cancer
Keywords: MAPK; bFGF; basic fibroblast growth factor; DLL4; Notch ligand delta-like 4; ERK; extracellular signal-regulated kinase; FDA; Food and Drug Administration; HIF; hypoxia-inducible factor; MAPK; mitogen-activated protein kinase; MMP; matrix metalloproteinase; m
Analysis of expression and function of FGF-MAPK signaling components in the hindbrain reveals a central role for FGF3 in the regulation of Krox20, mediated by Pea3
Keywords: MAPK; Hindbrain; Rhombomeres; FGF; MAPK; Pea3; Krox20; Chick embryo; Patterning
Glutamate induces neurotrophic factor production from microglia via protein kinase C pathway
Keywords: MAPK; NTFs; neurotrophic factors; BDNF; brain-derived neurotrophic factor; GDNF; glial cell line-derived neurotrophic factor; NGF; nerve growth factor; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid; iGluR; ionotropic glutamate receptor; mGluR; me
The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine
Keywords: MAPK; Hexosamine; Insulin; Growth factor; O-GlcNAc; Neurodegeneration; Cancer; Diabetes; Cardiovascular disease; mTOR; AMPK; AKT; MAPK
Possible anti-obesity therapeutics from nature - A review
Keywords: MAPK; ACC; acetyl-CoA carboxylase; AMPK; adenosine 5â²-monophosphate-activated protein kinase; BAT; brown adipocyte tissue; C/EBP; CCAAT enhancer binding protein; CNS; central nervous system; CPT; carnitine palmitoyltransferase-1; DHA; docosahexaenoic acid; EC
Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds
Keywords: MAPK; WKFRHTGMVITXBX-UHFFFAOYSA-N; Boc; tert-butoxycarbonyl; BRAF; V-RAF murine sarcoma viral oncogene homolog B1; DCM; dichloromethane; DMF; dimethylformamide; ERK; extracellular regulated kinase; MAPK; mitogen-activated protein kinase; MEK; MAPK/ERK kinase; M
Up-regulation of Krüppel-Like Factor 8 Promotes Tumor Invasion and Indicates Poor Prognosis for Hepatocellular Carcinoma
Keywords: MAPK; Small Interfering RNA; siRNA; Liver Cancer; Metastatic Liver Cancer; Tumor Microenvironment; AFP; α-fetoprotein; ALT; alanine aminotransferase; BCLC; Barcelona Clinic Liver Cancer; cDNA; complementary DNA; ChIP; chromatin immunoprecipitation; EMT; epithe
Transcriptomic analysis of patients with tetralogy of Fallot reveals the effect of chronic hypoxia on myocardial gene expression
Keywords: MAPK; 20; 29; BAX; Bcl-2-associated X protein; CPB; cardiopulmonary bypass; ELISA; enzyme-linked immunosorbent assay; ERK; extracellular signal-regulated kinase; FDR; false discovery rate; MAPK; mitogen-activated protein kinase; RVH; right ventricular hypertrop
Cross-talk between adipose and gastric leptins for the control of food intake and energy metabolism
Keywords: MAPK; ACTH; adrenocorticotropic hormone; ADIPOR1/2; adiponectin receptor1/2; AgRP; agouti related protein; AMPK; AMP-activated protein kinase; BSDL; bile salt-dependent lipase; cAMP; cyclic adenosine-monophosphate; CART; cocaine amphetamine related transcript;
Endothelin promotes neurite elongation by a mechanism dependent on c-Jun N-terminal kinase
Keywords: MAPK; Neuron; Neurite; Outgrowth; Vascular; Regeneration; MAPK; Endothelin
Suppression of endothelial t-PA expression by prolonged high laminar shear stress
Keywords: MAPK; Endothelium; Shear stress; Fibrinolysis; t-PA; MAPK; NF-κB;
MEK1-independent activation of MAPK and MEK1-dependent activation of p70 S6 kinase by stem cell factor (SCF) in ovarian cancer cells
Keywords: MAPK; Ovarian cancer; Stem cell factor; MEK; MAPK; Signal transduction;
NSC-87877, inhibitor of SHP-1/2 PTPs, inhibits dual-specificity phosphatase 26 (DUSP26)
Keywords: MAPK; PTP; protein tyrosine phosphatase; DUSP; dual-specificity protein phosphatase; NSC-87877; 8-hydroxy-7-(6-sulfonaphthalen-2-yl)diazenyl-quinoline-5-sulfonic acid; MAPK; mitogen-activated protein kinase; DUSP26; NSC-87877; Protein tyrosine phosphatase (PTP)
Reactive oxygen species production and MAPK activation are implicated in tetrahydrobiopterin-induced SH-SY5Y cell death
Keywords: MAPK; BH4; Dopaminergic neuron; MAPK; Reactive oxygen species; SH-SY5Y; Tetrahydrobiopterin;
Regulation of the activity and expression of ERK8 by DNA damage
Keywords: MAPK; ERK8; MAPK; DNA damage; MMS
Lycopene inhibits PDGF-BB-induced retinal pigment epithelial cell migration by suppression of PI3K/Akt and MAPK pathways
Keywords: MAPK; Lycopene; Retinal pigment epithelial cell; ARPE19; PDGF; Cell migration; Cell adhesion; Cytotoxicity; Proliferative vitreoretinopathy; PI3K/Akt; MAPK
Synthesis and biological evaluation of p38α kinase-targeting dialkynylimidazoles
Keywords: MAPK; Diradical; Carbene; MAPK; Inflammation
1-Aryl-3,4-dihydroisoquinoline inhibitors of JNK3
Keywords: MAPK; Kinase; Inhibitor; JNK; JNK3; MAPK; Selective
Neuroprotection of interleukin-6 against NMDA attack and its signal transduction by JAK and MAPK
Keywords: MAPK; Interleukin-6; Neuroprotection; Cerebellar granule neurons; NMDA; JAK; MAPK
Cationic lipids activate cellular cascades. Which receptors are involved?
Keywords: MAPK; AP-1; activator protein 1; CD 14/80/86; cluster of differentiation 14/80/86; diC14-amidine; N-t-butyl-Nâ²-tetradecyl-3-tetradecylaminopropionamidine; DAG; diacylglycerol; DMPC; dimyristoyl-phosphatidylcholine; DMPG; dimyristoyl-phosphatidylglycerol; DMKD
Increased expressions and activations of apoptosis-related factors in cell signaling during incised skin wound healing in mice: A preliminary study for forensic wound age estimation
Keywords: MAPK; Skin wound healing; MAPK; JNK; NOS; Calpain; Caspase; Wound age estimation
Intracellular signaling pathways activated by kisspeptins through GPR54: Do multiple signals underlie function diversity?
Keywords: MAPK; KiSS-1; Kisspeptin; Metastin; GPR54; Signaling; Ca2+; MAPK;
Inhibitory effects of ivermectin on nitric oxide and prostaglandin E2 production in LPS-stimulated RAW 264.7 macrophages
Keywords: MAPK; Ivermectin; NO; PGE2; iNOS; COX-2; MAPK
Anti-inflammatory activity of ethanol extract from Geranium sibiricum Linne
Keywords: MAPK; Geranium sibiricum Linne (GSL); MAPK; Nuclear factor (NF)-κB; Activator protein (AP)-1; Interleukin (IL)-1β; Human mast cells (HMC-1)
Signaling mechanism mediating the anti-senescence effect of low-concentration chemical stressors sprayed onto bean seedlings
Keywords: MAPK; BA; N6-benzylaminopurine; Chl; chlorophyll; CK; cytokinin; Ctrl; control; DAG; diacylglycerol; DCMU; 3-(3,4-dichlorophenyl)-1,1-dimethylurea; DW; dry weight; ERK; extracellular regulated kinase; FW; fresh weight; IMPase; myo-inositol-1-monophosphatase; MA
Bushen Ningxin Decoction pharmacological serum promotes the proliferation and suppresses the apoptosis of murine osteoblasts through MAPK pathway
Keywords: MAPK; Bushen Ningxin Decoction; Pharmacological serum; Osteoblasts; Apoptosis; MAPK