Keywords: 5-HT; 5-hydroxytryptamine; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CAMKII; Calcium/calmodulin-dependent protein kinase II; CaV; voltage-gated calcium (channel); CGRP; calcitonin gene-related peptide; CB; cannabinoid receptor; CNS; cen
مقالات ISI (ترجمه نشده)
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Keywords: Oxysterols; Survival; Nrf2; Autophagy; 5,6-S; 5,6-secosterol; 24OH; 24-hydroxycholesterol; 25OH; 25-hydroxycholesterol; 27OH; 27-hydroxycholesterol; 7K; 7-ketocholesterol; 7βOH; 7β-hydroxycholesterol; AGE; advanced glycation end products; AMPK; AMP-acti
Keywords: Beta cells; Diabetes; Eicosanoids; Fatty aldehyde dehydrogenase; Glutathione peroxidase; Glutathione-S-transferase4-hydroxyalkenals; 4-Hydroxynonenal; Lipid peroxidation; Phospholipase A; 12-HETE (PubChem CID: 5283155); 15-HETE (PubChem CID: 280724); 4-HN
Keywords: PM; particulate matter; O3; ozone; COPD; chronic obstructive pulmonary disease; PM2.5-10; PM with an aerodynamic diameter 2.5-10 μm; PM2.5; PM with an aerodynamic diameter less than 2.5 μm; PM0.1; PM with an aerodynamic diameter less than 0.1 μm
Keywords: Biotoxin; Bioterrorism; Biological warfare agent; BW; Biological warfare; CW; chemical weapons; BWAs; Biological warfare agents; BoNTs; Clostridium botulinum neurotoxins; LD50; median lethal dose; PBT; pentavalent botulinum toxoid; SEB; Staphylococus aure
Keywords: AP-1; adaptor protein 1; ASL; airway surface liquid; CCO; cytochrome c oxidase; CF; cystic fibrosis; COX-2; cyclooxygenase 2; Csk; c-src kinase; DMEM; Dulbeccos' minimal essential medium; DMT1; divalent metal ion transporter 1; DUOX; dual oxidase; EGFR;
Keywords: ADC; arginine decarboxylase; BBL; berberine bridge enzyme-like; bHLH; basic helix-loop-helix; DMN; dihydrometanicotine; ERF; ethylene response factor; JA; jasmonic acid; JAZ; jasmonate ZIM-domain; MAPKK; mitogen-activated protein kinase kinase; MATE;
Strategies of biochemical adaptation for hibernation in a South American marsupial Dromiciops gliroides: 1. Mitogen-activated protein kinases and the cell stress response
Keywords: CREB; cAMP response element binding protein; ERK; extracellular signal-regulated protein kinase; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; MAPKK; MAPK kinase; MAPKKK; MAPKK kinase; p38; p38 protein kinase; TNF-α; tumor necrosi
Subtle regulation of cotton resistance to Verticillium wilt mediated by MAPKK family members
Keywords: Cotton; Verticillium wilt; MAPKK; Resistance regulation;
Inhibition of anthrax lethal factor by ssDNA aptamers
Keywords: BSA; bovine serum albumin; CD; circular dichroism; DMEM; Dulbecco's Modified Eagle Medium; DMSO; dimethyl sulfoxide; EMSA; electrophoretic mobility shift assay; EF; Edema factor; FBS; fetal bovine serum; GST; Glutathione S-transferase; LF; lethal factor;
A constitutively-active IKK-complex at the axon initial segment
Keywords: Axon initial segment; NF-κB; IKK 2 Kinase; Ankyrin-G; Proximity ligation assay; Axon; AIS; axon initial segment; ASA; acetyl-salicylic acid; DMEM; Dulbecco's modified Eagle media; eGFP; enhanced green-fluorescent protein; FADD; Fas-associated death dom
Fgf regulates dedifferentiation during skeletal muscle regeneration in adult zebrafish
Keywords: EdU; 5-ethynyl-2â²-deoxyuridine; EOM; extraocular muscle; hpi; hours post injury; dpi; days post injury; Fgf; fibroblast growth factor; Fgfr; fibroblast growth factor receptor; LR; lateral rectus; Tc; cell cycle length; Ts; length of S-phase; MAPK; mitog
Identification of a novel Ser/Thr protein phosphatase Ppq1 as a negative regulator of mating MAP kinase pathway in Saccharomyces cerevisiae
Keywords: MAPK; mitogen-activated protein kinase; MAPKK; mitogen-activated protein kinase kinase; MAPKKK; mitogen-activated protein kinase kinase kinase; PP1; Phosphoprotein phosphatase 1; yEGFP; yeast enhanced green fluorescent protein; pNPP; p-nitrophenyl phospha
Valproic acid suppresses lipopolysaccharide-induced cyclooxygenase-2 expression via MKP-1 in murine brain microvascular endothelial cells
Keywords: AREs; AU-rich elements; BBB; blood-brain barrier; C/EBPβ; CCAAT enhancer binding protein beta; CNS; central nervous system; COX-2; cyclooxygenase-2; HAT; histone acetyltransferase; HDAC; histone deacetylase; JNK; c-Jun N-terminal kinase; LPS; lipopolys
Nemo-like kinase, a multifaceted cell signaling regulator
Keywords: NLK; Nemo-like kinase; IL-6; intereukin-6; MAPK; mitogen activated protein kinase; ERK; extracellular-signal regulated kinase; Pro; proline; Ser; serine; Thr; threonine; C. elegans; Caenorhabditis elegans; POP-1; Posterior pharynx defect protein 1; LEF1;
p38 mitogen-activated protein kinase (p38 MAPK)-mediated autoimmunity: Lessons to learn from ANCA vasculitis and pemphigus vulgaris
Keywords: AIH; autoimmune hepatitis; ANCA; anti-neutrophil cytoplasmic antibody; DSG; desmoglein; DUSP; dual specificity phosphatase; EAE; experimental autoimmune encephalomyelitis; GADD45; growth arrest and DNA damage inducible gene 45; GC; germinal center; HSP; h
Tau protein kinases: Involvement in Alzheimer's disease
Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; Arg; Abl-related gene; SFK; Src family kinase; Aβ; β-amyloid; BBB; blood brain barrier; LD50; lethal dose 50; c-Abl; c-Abelson; Cables; c-Abl-binding adaptator protein; CaMKII; Ca2+/calmodulin-dep
Redox signaling loops in the unfolded protein response
Keywords: AGR2; anterior gradient 2; ARE; antioxidant responsive element; ATF4; activating transcription factor-4; ATF6; activating transcription factor-6; ASK1; apoptosis signal-regulating kinase-1; BI-1; BAX inhibitor-1; BiP; immunoglobulin heavy chain-binding pr
Reactive oxygen species participate in the p38-mediated apoptosis induced by potassium deprivation and staurosporine in cerebellar granule neurons
Keywords: K25; high potassium; K5; potassium deprivation; CGN; cerebellar granule neurons; Kmp; kaempferol; CAT; catalase; SOD; superoxide dismutase; SB; SB203580; DHEt; dihydroethidium; FDA; flourescein diacetate; PI; propidium iodide; DIV; days in vitro; MAPKs; m
The enhanced host-cell permissiveness of human cytomegalovirus is mediated by the Ras signaling pathway
Keywords: DMEM; Dulbecco's Modified Eagle's Medium; E; Early; EBV; Epstein-Barr virus; EGF; Epidermal Growth Factor; EGFR; Epidermal Growth Factor Receptor; ERK; Extracellular Regulated Kinase; FBS; Fetal Bovine Serum; FTI; Farnesyl Transferase Inhibitor; HFF; Huma
Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis
Keywords: DEVD.fmk; benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe) fluoromethyl ketone; DTT; dithiothreitol; EDTA; ethylene diamine tetra-acetic acid; FADD; Fas-associated death domain; GAP; GTPase activating protein; IB1; Islet Brain 1; JSAP; JNK/SAPK-associated
Cadmium activates Arabidopsis MPK3 and MPK6 via accumulation of reactive oxygen species
Keywords: Cd; cadmium; Zn; zinc; Cu; copper; MAPK; mitogen-activated protein kinase; MAPKK; mitogen-activated protein kinase kinase; MAPKKK; mitogen-activated protein kinase kinase kinase; GSH; glutathione; DAB; 3,3-diaminobenzidine; ROS; reactive oxygen species; M
The activation of p38alpha, and not p38beta, mitogen-activated protein kinase is required for ischemic preconditioning
Keywords: βKO; p38β knock-out; I/R%; myocardial infarction as a percentage of myocardium at risk of infarction; DRα; drug-resistant p38α; DRβ; drug-resistant p38β; HSP27; heat stress protein of 27 kDa; MAPK; mitogen-activated protein kinase; MAPKK; mitogen-a
Herpesviruses: Hijacking the Ras signaling pathway
Keywords: BL; Burkitt's lymphoma; COX-2; cytochrome c oxidase subunit II; E; Early; EBNA; Epstein-Barr nuclear antigen; EBV; Epstein-Barr virus; EGF; Epidermal Growth Factor; EGFR; Epidermal Growth Factor Receptor; Elk; Ets-related transcription factor; ERK; ex
PACAP protects against TNFα-induced cell death in olfactory epithelium and olfactory placodal cell lines
Keywords: AA; amino acid; AC; adenylate cyclase; BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; CNS; central nervous system; dNTP; deoxynucleotide triphosphate; dT; deoxythymidine; EC1; first extracellular domain of PAC1R sequence; FBS; fetal bovi
Inhibition of the MAP kinase ERK protects from lipopolysaccharide-induced lung injury
Keywords: COPD; chronic obstructive pulmonary disease; MAPKK; mitogen-activated protein kinase kinase; MAPKKK; mitogen-activated protein kinase kinase kinase; LPS; lipopolysaccharide; ERK; extracellular signal-related kinase; MEK; extracellular signal-regulated kin
The Gα4 G protein subunit interacts with the MAP kinase ERK2 using a D-motif that regulates developmental morphogenesis in Dictyostelium
Keywords: PCR; polymerase chain reaction; MAP kinase; mitogen-activated protein kinase; MAPKK; MAP kinase kinase; ERK; extracellular signal-regulated kinase; CD; common docking site; D-motif; MAPK docking site; SDS; sodium dodecyl sulfate; cAMP; cyclic adenosine mo
A Polymorphism in MAPKAPK3 Affects Response to Interferon Therapy for Chronic Hepatitis C
Keywords: GAS; interferon-γ-activated site; IFN; interferon; IFNAR1; type I interferon receptor-1; ISRE; interferon-stimulated response element; JAK; Janus-activated kinase; MAP; mitogen-activated protein; MAPKAPK; mitogen-activated protein kinase-activated pr
TAB2, a nucleoside diphosphate protein kinase, is a component of the tMEK2 disease resistance pathway in tomato
Keywords: Nucleoside diphosphate protein kinase; MAPKK; Protein interaction; Disease resistance; Tomato2DE, two-dimensional electrophoresis; KIM, kinase interaction motif; LC–MS/MS, liquid chromatography–tandem mass spectrometry; MALDI, matrix-assisted laser desorp
The nerve growth factor and its receptors in airway inflammatory diseases
Keywords: ADAM; a disintegrin and metalloprotease domain; AP-1; activating protein 1; AP-2; clathrin adaptative protein-2; APPL; amyloid precursor protein-like; ARMS; ankyrin repeat-rich membrane spanning; BDNF; brain-derived neurotrophic factor; bFGF; basic fibrob
Function and regulation in MAPK signaling pathways: Lessons learned from the yeast Saccharomyces cerevisiae
Keywords: Mitogen_activated protein kinase; MAPK; Fus3; Kss1; Hog1; Mpk1/Slt2; Smk1; Mitogen_activated protein kinase kinase; MAPKK; Ste7; Pbs2; Mkk1; Mkk2; Mitogen_activated protein kinase kinase kinase; MAPKKK; Ste11; Ssk2; Ssk22; Bck1; Mitogen_activated protein
Molecular cloning and characterization of a novel MAP kinase gene in Chorispora bungeana
Keywords: RACE; Mitogen-activated protein kinases; Chorispora bungeana; Environmental stresses; ABA; Abscisic acid; MAPK; mitogen-activated protein kinase; MAPKK; MAPK kinase; MAPKKK; MAPKK kinase; ORF; Open reading frame; RACE; Rapid amplification of cDNA ends; RT
Alteration of activator protein 1 DNA binding activity in gentamicin-induced hair cell degeneration
Keywords: aminoglycosides; immediate early genes; inner and outer hair cells; organ of Corti; signaling pathways; AP-1; activating protein-1; EMSA; electrophoretic-mobility-shift-assay; ERK; extracellular signal-related kinase; FBS; fetal bovine serum; FITC; fluore
Evolutionary perspectives on innate immunity from the study of Caenorhabditis elegans
Keywords: DAF; abnormal dauer formation; ERK; extracellular signal-related kinase; JNK; c-Jun amino-terminal kinase; MAP; mitogen-activated protein; MAPK; MAP kinase; MAPKK; MAPK kinase; NLP; neuropeptide-like protein; PMK; p38 mitogen-activated protein kinase fami
Evidence that C-terminal non-kinase domain of Pbs2p has a role in high osmolarity-induced nuclear localization of Hog1p
Keywords: MAPKK; PBS2; HOG pathway; Debaryomyces hansenii;
Kinase signaling cascades in the mitochondrion: a matter of life or death
Keywords: AKAP; A-kinase anchoring protein; Akt/PKB; protein kinase B; DAG; diacylglycerol; ERK; extracellular signal-regulated protein kinase; GSK3β; glycogen synthase kinase 3β; IP3; inositol triphosphate; JNK/SAPK; c-Jun N terminal kinase/stress-activated prot
The neuroprotective effects of K252a through inhibiting MLK3/MKK7/JNK3 signaling pathway on ischemic brain injury in rat hippocampal CA1 region
Keywords: K252a; MLK3; MKK7; JNK3; c-Jun; cerebral ischemia; AP-1; activator protein-1; ASK1; apoptosis signal-regulated kinase 1; BSA; bovine serum albumin; DMSO; dimethyl sulfoxide; HEPES; N-[2-hydroxyethyl]-piperazine-Nâ²-[2-ethanesulfonic acid]; I/R; ischemia/
Protein kinases as targets for antimalarial intervention: Kinomics, structure-based design, transmission-blockade, and targeting host cell enzymes
Keywords: CamK; calmodulin kinase; CDK; cyclin-dependent kinase; CDPK; calcium-dependent protein kinase; CK1; casein kinase 1; CQ; chloroquine; EPK; eukaryotic protein kinase domain; ERK; extracellular signal-regulated kinase; GSK3; glycogen synthase kinase 3; Hb;
l-γ-Glutamyl-l-cysteinyl-glycine (glutathione; GSH) and GSH-related enzymes in the regulation of pro- and anti-inflammatory cytokines: a signaling transcriptional scenario for redox(y) immunologic sensor(s)?
Keywords: NAC; N-acetyl-l-cysteine; AIDS; acquired immune deficiency syndrome; RANTES; activation normal T cell expressed and secreted; AP; activator/activating protein; ARDS; acute respiratory distress syndrome; ARE; antioxidant response element; ARNT; aryl-hydroc
N-methyl-d-aspartate (NMDA) and the regulation of mitogen-activated protein kinase (MAPK) signaling pathways: A revolving neurochemical axis for therapeutic intervention?
Keywords: AA; arachidonic acid; AIDS; acquired immunodeficiency syndrome; ALS; amyotrophic lateral sclerosis; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; APV; 2-amino-5-phosphonovalerate; 2-AP5; 2-amino-5-phosphonopentanoic acid; ATF; activating tr