
Structure-based epitope and PEGylation sites mapping of phenylalanine ammonia-lyase for enzyme substitution treatment of phenylketonuria
Keywords: طیف سنجی جرمی; Phenylketonuria; Phenylalanine ammonia-lyase; Epitope mapping; Immunodominant; PEGylation; Enzyme therapy; Protein engineering; Mass spectroscopy;