دانلود مقالات ISI درباره Mda5 + ترجمه فارسی

گیرنده های شناسایی الگوی هدف برای کشف مولکول های کوچک مولکولی کوچک

Targeting pattern-recognition receptors to discover new small molecule immune modulators

Keywords: Pattern-recognition receptors (PRRs); Toll-like receptors (TLRs); RIG-I-like receptors (RLRs); NOD-like receptors (NLRs); Small molecule modulators; BIR; baculovirus inhibitor repeat; CARD; caspase recruitment domains; CFS; chronic fatigue syndrome; CLR;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

سلول های ایمنی و سلول های غیر ایمنی با عملکرد ایمنی در کچلی پستانداران

Immune cells and non-immune cells with immune function in mammalian cochleae

Keywords: Cochlea; Immunity; Macrophage; Inflammation; TLR; Toll-like receptor; RIG-I; Retinoic acid inducible gene-I; MDA5; Melanoma differentiation-associated gene 5; TGF-β; Transforming growth factor beta; MHC-II; major histocompatibility complex II; ICAM-1; In

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

با توجه به دفاعی: کنترل ایمنی از عفونت ویروس زیکا

Taking the defensive: Immune control of Zika virus infection

Keywords: Zika virus; Type I interferon; RIG-I; MDA5; RIG-I signaling; Flavivirus; Viral antagonism; Innate immunity; JAK/STAT signaling; Antibody; T cells;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

فاکتور فشرده سازی پرولین / گلوتامین غنی یک آنتی ژن جدید رماتیسمی است که با آنتی بادی های ژنی 5 مرتبط با تمایز ضد ملانوم

Splicing factor proline/glutamine-rich is a novel autoantigen of dermatomyositis and associated with anti-melanoma differentiation-associated gene 5 antibody

Keywords: SFPQ; MDA5; Myositis; Antibody; CADM; Virus;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

میکروبیوم پوست و سلول های مشتق شده

Skin microbiome and mast cells

Keywords: AD; atopic dermatitis; AMP; antimicrobial peptide; CAPS; cryopyrin-associated periodic syndrome; CPA; carboxypeptidase A; CTMC; connective tissue mast cell; dsRNA; double-stranded RNA; GF; germ-free; HSV; herpes simplex virus; Ig; immunoglobulin; IL; inte

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

الگوی هیستوپاتولوژیک ریه در یک بازماندگان با بیماری ریه ای که به سرعت در حال پیشرفت است و ژن 5 مرتبط با تمایز آنتی مالانوما با آنتی بادی مثبت بالینی درماتومیوزیت آمیوپاتی

Lung histopathological pattern in a survivor with rapidly progressive interstitial lung disease and anti-melanoma differentiation-associated gene 5 antibody-positive clinically amyopathic dermatomyositis

Keywords: CADM; RP-ILD; MDA5; Lung histopathological pattern; DADMDA5, melanoma differentiation-associated gene 5; CADM, clinically amyopathic dermatomyositis; RP-ILD, rapidly progressive interstitial lung disease; DAD, diffuse alveolar damage; CT, computed tomogra

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

ساختارهای واکنش دهنده و واکنش های دیفرانسیل به القا کننده های ویروسی و غیر ویروسی ژن 5 مرتبط با تمایز ملانوم مرغ

Promoter structures and differential responses to viral and non-viral inducers of chicken melanoma differentiation-associated gene 5

Keywords: MDA5; Promoter; Chicken; Innate immunology; RIG-I-like receptor (RLR); Virus;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

ناهنجاری های ارثی گیرنده های ایمنی ذاتی در بیماری های التهابی کودکان مبتلا

Inherited anomalies of innate immune receptors in pediatric-onset inflammatory diseases

Keywords: ACP5; Acid phosphatase 5; ADAR1; Adenosine deaminase RNA-specific 1; AGS; Aicardi-Goutières syndrome; ALRs; AIM2-like receptors; AIM2; Absent in melanoma 2; ASC; Apoptosis-associated speck-like protein containing a CARD; CANDLE; Chronic atypical neutroph

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

تنظیم عملکرد ماکروفاژ و سلول های دندریتیک توسط پاتوژن ها و از طریق ایمونوادوالسیون در مخاط مخاطی

Regulation of macrophage and dendritic cell function by pathogens and through immunomodulation in the avian mucosa

Keywords: Ag; antigen; APC; antigen-presenting cells; AIV; avian influenza virus; BM; bone marrow; BALT; bronchus-associated lymphoid tissue; CG; chicken galectin; cLL; chicken lung lectin; CLR; C-type lectin receptors; DC; dendritic cells; DC-SIGN; DC-specific int

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

گیرنده های سطحی سلول های نوتروفیل و مسیرهای انتقال سیگنال داخل سلولی آنها

Neutrophil cell surface receptors and their intracellular signal transduction pathways

Keywords: Abl; Abelson leukemia proto-oncogene; ADAP; adhesion and degranulation promoting adapter protein (Fyb, SLAP-130); Asc; apoptosis-associated speck-like protein containing a CARD; BCR; B-cell receptor; C3G; Crk SH3 domain-binding guanine nucleotide exchange

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of inflammatory factors by double-stranded RNA receptors in breast cancer cells

Keywords: APCs; antigen presenting cells; BM-DCs; bone marrow-derived DCs; DCs; dendritic cells; DAMPs; danger associated molecular patterns; ELISA; enzyme-linked immunosorbent assay; FACS; fluorescence-activated cell sorting; GAPDH; glyceraldehyde-3-phosphate dehy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Aminoacyl-tRNA synthetases, therapeutic targets for infectious diseases

Keywords: ARS; aminoacyl-tRNA synthetase; TLR; toll-like receptor; RIG-I; retinoic acid-inducible gene-I; MAVS; mitochondrial antiviral signaling protein; IFN; interferon; ITCH; E3 ubiquitin-protein ligase Itchy homolog; MSC; multi-tRNA synthetase complex; AIMP; AR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

The role of type I interferons in innate and adaptive immunity against viruses in Atlantic salmon

Keywords: Adjuvant; DNA vaccine; Fish; IFN; ISG; TLR; CRFB; class II cytokine receptor family member; HE; hemagglutininesterase; IFN; interferon; IFN-I; type I IFN; IFNAR; mammalian type I IFN receptor; IPNV; infectious pancreatic necrosis virus; IPS-1; interferon

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Rig-I is involved in inflammation through the IPS-1/TRAF6 pathway in astrocytes under chemical hypoxia

Keywords: RIG-I; retinoic acid-inducible gene I; IPS-1; interferon-β promoter stimulator-1; TRAF; TNF receptor-associated factor; PRRs; pattern recognition receptors; TLRs; toll-like receptors; NLRs; NOD-like receptors; RLRs; RIG-like receptors; MDA5; melanoma dif

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of a novel porcine OASL variant exhibiting antiviral activity

Keywords: JEV; Japanese encephalitis virus; IFNs; interferons; ISGs; IFN-stimulated genes; OAS; 2',5'-oligoadenylate synthetase; PRRs; pattern-recognition receptors; RNase L; ribonuclease L; RIG-I; retinoic acid-inducible gene I; MDA5; melanoma differentiation-

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-melanoma differentiation-associated gene 5 (MDA5) dermatomyositis: A concise review with an emphasis on distinctive clinical features

Keywords: dermatomyositis; interstitial lung disease; MDA5; melanoma differentiation-associated gene 5; myositis; palmar papule; ulceration; CADM; clinically amyopathic dermatomyositis; CT; computed tomography; DLCO; diffusion capacity of the lung for carbon mono

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

The proinflammatory effects of macrophage-derived NADPH oxidase function in autoimmune diabetes

Keywords: ABIS; All Babies in Southwest Sweden study; APC; Antigen presenting cells; Arg-1; Arginase 1; CB3; Coxsackievirus strain B3; CB4; Coxsackievirus strain B4; CGD; Chronic granulomatous disease; CSF-1; Colony-stimulating factor 1; AISY; Diabetes Autoimmunity

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular characterisation, ontogeny and expression analysis of melanoma differentiation-associated factor 5 (MDA5) from Asian seabass, Lates calcarifer

Keywords: Melanoma differentiation-associated protein 5; MDA5; RLR; PRR; Asian seabass; Lates calcarifer; Bacterial infection; Poly I:C; Gene expression; Ontogeny;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Hepatitis D virus replication is sensed by MDA5 and induces IFN-β/λ responses in hepatocytes

Keywords: Hepatitis D virus; Hepatitis B virus; Innate immunity; Pattern recognition receptor; MDA5; Interferon induction; Interferon treatment; Hepatocytes;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll-Like Receptor 3 in Hepatocytes

Keywords: Exosomes; Escape; Virology; Rab27a; DMV; double-membrane vesicle; dsRNA; double-stranded RNA; EVs; extracellular vesicles; gt; genotype; HAV; hepatitis A virus; HCV; hepatitis C virus; HCVcc; cell culture derived HCV; IFIT1 or 3; interferon-induced protei

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2018 سفارش ترجمه

HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon

Keywords: Coinfection; Interferon-stimulated Gene; PRR; RIG-I; APOBEC; apolipoprotein B mRNA editing enzyme catalytic subunit; cccDNA; covalently closed circular DNA; CHB; chronic hepatitis B; circDNA; circular DNA; GFP-IRF3; green fluorescent protein-interferon

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2018 سفارش ترجمه

PACT is required for MDA5-mediated immunoresponses triggered by Cardiovirus infection via interaction with LGP2

Keywords: LGP2; PACT; MDA5; Type-I interferon; RIG-I-like receptors; Picornavirus; Cardiovirus;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

microRNA-145 regulates the RLR signaling pathway in miiuy croaker after poly(I:C) stimulation via targeting MDA5

Keywords: MicroRNAs; microRNA-145; MDA5; RLRs; Negatively regulate;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

The innate immune response to RSV: Advances in our understanding of critical viral and host factors

Keywords: ATF6; activated transcription factor 6; BAP31; B-cell receptor-associated protein 31; Bcl2; B-cell lymphoma 2; DR4/5; death receptor 4/5; DUOX2; dual oxidase 2; DVGs; defective viral genomes; IB; inclusion body; IFIT1; interferon-induced protein with tetr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Innate immunity related pathogen recognition receptors and chronic hepatitis B infection

Keywords: acLDL; acylated LDL; AIM2; absent in melanoma 2; AP-1; activator protein 1; BDCA-2; blood DC antigen; BEC; biliary epithelial cells; CARD; caspase recruitment and activation domains; cDC; common dendritic cells; CL-L1; collectin liver 1; CL-K1; collectin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

The antiviral signaling mediated by black carp MDA5 is positively regulated by LGP2

Keywords: MDA5; LGP2; Black carp; Innate immunity;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Spontaneous activation of a MAVS-dependent antiviral signaling pathway determines high basal interferon-β expression in cardiac myocytes

Keywords: Cardiac myocyte; Cardiomyocyte; Interferon; Mitochondria; MAVS; MAM; ER; endoplasmic reticulum; IFN; interferon; IKK; IκB kinase; ISG; interferon-stimulated gene; MAM; mitochondrial-associated ER membranes; MAVS; mitochondrial antiviral signaling; MDA5;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Human B cells fail to secrete type I interferons upon cytoplasmic DNA exposure

Keywords: IFN I; type I interferon(s); IFI16; interferon-inducible protein 16; cGAMP; cyclic GMP-AMP; cGAS; cGAMP synthase; STING; stimulator of interferon genes; TBK1; TANK-binding kinase 1; IRF3; interferon regulatory factor 3; ISG; interferon-stimulated genes; P

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

The anticancer functions of RIG-I-like receptors, RIG-I and MDA5, and their applications in cancer therapy

Keywords: 5′PP; 5′-diphosphate; 5′ppp; 5′triphosphorylated; Bcl2; B-cell lymphoma-2; BIRC3; baculoviral IAP repeat-containing 3; CARDs; caspase activation and recruitment domains; CRC; colorectal cancer; CTD; C-terminal domain; CTLs; cytotoxic T lymphocytes

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Fish TRIM32 functions as a critical antiviral molecule against iridovirus and nodavirus

Keywords: TRIM32; Grouper; Antiviral; Interferon; MDA5;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Zebrafish STAT6 negatively regulates IFNφ1 production by attenuating the kinase activity of TANK-binding kinase 1

Keywords: STAT6; Negative regulator; Interferon; TBK1; Zebrafish; CIP; calf intestinal phosphatase; CPE; cytopathic effect; EPC; epithelioma papulosum cyprini; GAS; interferon gamma activated sequence; IFN; interferon; IRF; IFN regulatory factor; IRF3; interferon r

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Duox2 is required for the transcription of pattern recognition receptors in acute viral lung infection: An interferon-independent regulatory mechanism

Keywords: Influenza A virus; Duox2; RIG-I; MDA5; Acute viral lung infection;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Gene expression profiling reveals the role of RIG1 like receptor signaling in p53 dependent apoptosis induced by PUVA in keratinocytes

Keywords: PUVA; 8-methoxypsoralen plus UVA; RIG-1; retinoic acid induced gene 1; MDA5; melanoma differentiation associated gene 5; MAVS; mitochondrial antiviral signaling protein; TBK; TANK-binding kinase 1; IKKε; inhibitor of kappaB kinase epsilon; IRF3; interfer

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Comprehensive assessment of myositis-specific autoantibodies in polymyositis/dermatomyositis-associated interstitial lung disease

Keywords: Polymyositis; Dermatomyositis; Myositis-specific autoantibody; Interstitial pneumonia; ARS; MDA5; ARS; aminoacyl tRNA-synthetase; BAL; bronchoalveolar lavage; CADM; clinically amyopathic dermatomyositis; CT; computed tomography; DM; dermatomyositis; GGA;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Antiviral function of grouper MDA5 against iridovirus and nodavirus

Keywords: MDA5; Grouper; Iridovirus; RGNNV; Antiviral

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Both RIG-I and MDA5 detect alphavirus replication in concentration-dependent mode

Keywords: Alphaviruses; Virus-host interactions; Innate immunity; Pattern recognition receptors; RIG-I; MDA5; Type I interferon;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Comparative transcriptome analyses indicate enhanced cellular protection against FMDV in PK15 cells pretreated with IFN-γ

Keywords: IFN-γ; Interferon gamma; FMDV; Foot and mouth disease virus; ISGs; IFN-stimulated genes; FMD; Foot-and-mouth disease; DGE; Digital gene expression; FDR; False discovery rate; GO; Gene Ontology; KEGG; Kyoto Encyclopedia of Genes and Genomes; qRT-PCR; Quan

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Testicular immunoregulation and spermatogenesis

Keywords: BTB; blood-testis barrier; EAO; experimental autoimmune orchitis; Gas6; growth arrest-specific gene 6; IRF3; interferon regulatory factor 3; IPS-1; IFN-β; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinases; MDA5; melanoma differentiation-

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Involvement of zebrafish RIG-I in NF-κB and IFN signaling pathways: Insights into functional conservation of RIG-I in antiviral innate immunity

Keywords: RIG-I; retinoic acid-inducible gene I; PRRs; pattern recognition receptors; IFN-I; type I IFN; TLRs; toll-like receptors; RLRs; retinoic acid-inducible gene I (RIG-I)-like receptors; MDA5; melanoma differentiation associated factor 5; LGP2; laboratory of

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

A DN-mda5 transgenic zebrafish model demonstrates that Mda5 plays an important role in snakehead rhabdovirus resistance

Keywords: Zebrafish; Danio rerio; Mda5; Rhabdovirus; Type I IFN; Antiviral

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Transcriptome comparative analysis revealed poly(I:C) activated RIG-I/MDA5-mediated signaling pathway in miiuy croaker

Keywords: Transcriptome; Poly(I:C); MDA5; TLR3; Signaling pathwayGO, Gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; DEGs, differentially expressed genes; ISGF3, IFN-stimulated gene factor 3; ISGs, IFN-stimulated genes; PRRs, host pattern recognition

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

DNA mismatch repair enzymes: Genetic defects and autoimmunity

Keywords: AA; aplastic anemia; ARS; aminoacyl tRNA synthetase; CMMR-D; constitutional mismatch repair-deficiency syndrome; DM; dermatomyositis; DM1; myotonic dystrophy type I; DNA-PKcs; DNA-dependent protein kinase; ELISA; enzyme-linked immunosorbent assay; HD; Hun

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleMDA5 plays a critical role in interferon response during hepatitis C virus infection

Keywords: HCV; hepatitis C virus; RIG-I; retinoic acid inducible gene I; MDA5; melanoma differentiation-associated gene 5; IFN; interferon; UTR; untranslated region; MAVS; mitochondrial antiviral signaling protein; PAMP; pathogen-associated molecular patterns; HCVc

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Inflammasome signaling pathways exert antiviral effect against Chikungunya virus in human dermal fibroblasts

Keywords: AIM2; absent in melanoma 2; ASC; apoptosis-associated speck-like protein containing a caspase recruitment domain; CHIKV; Chikungunya virus; ds; double-stranded; hpi; hours post infection; ISG; interferon-stimulated gene; MDA5; Melanoma differentiation-ass

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

CpA/CpG methylation of CiMDA5 possesses tight association with the resistance against GCRV and negatively regulates mRNA expression in grass carp, Ctenopharyngodon idella

Keywords: Grass carp (Ctenopharyngodon idella); MDA5; CpA; DNA methylation; mRNA expression; Grass carp reovirus;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Functions of the two zebrafish MAVS variants are opposite in the induction of IFN1 by targeting IRF7

Keywords: MAVS variants; Negative regulator; Interferon; IRF7; Zebrafish; CARD; caspase recruiting domain; CPE; cytopathic effect; DBD; DNA binding domain; EPC; epithelioma papulosum cyprini; GBP4; guanylate binding protein 4; IFN; interferon; IKKε; IkappaB kinase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleControl of temporal activation of hepatitis C virus-induced interferon response by domain 2 of nonstructural protein 5A

Keywords: HCV; hepatitis C virus; RIG-I; retinoic acid-inducible gene 1; TLR-3; Toll-like receptor 3; RLR; RIG-I like receptor; MDA5; Melanoma Differentiation-Associated protein 5; IFN; interferon; IRF-3; IFN regulatory factor-3; ISG; IFN-induced gene; MAVS; mitoch

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

LGP2 synergy with MDA5 in RLR-mediated RNA recognition and antiviral signaling

Keywords: Antiviral immunity; RIG-I-like receptors; MDA5; LGP2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

RNA degradation in antiviral immunity and autoimmunity

Keywords: nonsense-mediated decay; RNA exosome; pattern-recognition receptor; type I interferon; Aicardi-Goutières syndrome; MDA5;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Functions of MDA5 and its domains in response to GCRV or bacterial PAMPs

Keywords: Grass carp (Ctenopharyngodon idella); MDA5; RLR pathway; GCRV; CIK cells

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه