Keywords: MDM2; ABC; ATP-binding cassette; AKT; V-Akt murine thymoma viral oncogene homolog; ALDH1; aldehyde dehydrogenase 1; AR; androgen receptor; Bad; Bcl-2-associated death promoter; Bak; Bcl-2 homologous antagonist killer; Bax; Bcl-2-associated X protein; Bcl-2; B-c
مقالات ISI MDM2 (ترجمه نشده)
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Keywords: MDM2; 4- Shogaol (PubChem CID: 9794897); 6- Shogaol (PubChem CID: 5281794); Apigenin (PubChem CID: 5280443); Berberine (PubChem CID: 2353); Bergamottin (PubChem CID: 5471349); Caffeic acid (PubChem CID: 689043)Capsaicin (PubChem CID: 1548943); Cardamonin (PubCh
Keywords: MDM2; Ub; ubiquitin; UBLs; ubiquitin-like proteins; DUBs; deubiquitinating enzymes; TCR; T cell receptor; UPS; ubiquitin-proteasome system; IAPs; inhibitors of apoptosis-related proteins; GAPs; GTPase-activating proteins; PI3K; phosphatidylinositol 3-kinase;
Keywords: MDM2; ACTB; actin-β; ACTG1; actin-γ1; ADA; American Diabetes Association; Ascl1; achaete-scute homolog 1; BMPR2; bone morphogenetic protein receptor type 2; CCNG2; cyclin G2; CNS; central nervous system; CRKL; CRK-like proto-oncogene adaptor protein; CSNK2A2;
Keywords: MDM2; ACC; acetyl-CoA carboxylase; ALDOA; aldolase A; AIs; aromatase inhibitors; AMPK; AMP-activated protein kinase; BC; breast cancer; CML; chronic myelogenous leukemia; CT; computed tomography; CPT1; carnitine palmitoyltransferase 1; CRC; colorectal cancer; 2
Keywords: MDM2; AA; amino acid; Aβo; oligomeric β-amyloid; Aβ; β-amyloid; AD; Alzheimer's disease; α7nAChR; α7 nicotinic acetylcholine receptor; ALS; amyotrophic lateral sclerosis; APLP1; amyloid beta precursor-like protein 1; APP; amyloid precursor protein; β-A
Keywords: MDM2; HCC; Hepatocellular carcinoma; DH; Dysplastic hepatocytes; Mdm2; Mouse double minute 2; PFT; Pfithrin-α; PH; Primary hepatocytes; HBSS; Hank's balanced salt solution; EDTA; Ethylenediaminetetraacetic acid; BSA; Bovine serum albumin; FACS; Fluorescence ac
Keywords: MDM2; AAV; adeno-associated virus; Arx; aristaless-related homeobox; BA; biliary atresia; BAC; bacterial artificial chromosome; BDL; bile duct ligation; CD; campomelic dysplasia; CDE; choline-deficient ethionine-supplemented diet; Cdx2; caudal type homeobox 2;
Keywords: MDM2; Cancer; Inflammation; Sesquiterpenoid; MDM2; p53; NF-κB;
27-hydroxycholesterol: A novel player in molecular carcinogenesis of breast and prostate cancer
Keywords: MDM2; 27-OHC; 27-hydroxycholesterol; ADT; androgen deprivation therapy; AR; androgen receptor; ATF4; Activating Transcription Factor 4; ATF6; Activating Transcription Factor 6; C/EBP; CCAAT / Enhancer binding proteins; CHOP; C/EBP homologous protein; CIP2A; can
Keywords: MDM2; Aptamer; Apoptosis; Targeted therapy; Intrinsic apoptosis pathway; Extrinsic apoptosis pathway; Intramer; Akt; PKB (protein kinase B); Bcl; B-cell lymphoma family protein; BH; Bcl-2 homology domain; Bmi-1; B lymphoma Mo-MLV insertion region 1; CD; cluster
Keywords: MDM2; AFP; Alpha-fetoprotein; ANAs; Antinuclear antibodies; APCs; Antigen presenting cells; ANXA-1; Annexin A1; BRCA; Breast cancer susceptibility gene; CT; Cancer-testis; EGFR; Epidermal growth factor receptor; ELISA; Enzyme linked immunosorbent assay; HDR; Ho
Keywords: MDM2; AIF; apoptosis inducing factor; Ang; angiopoietin; AP-1; activator protein-1; APEX; Assessment of Proteasome Inhibition for Extending Remissions; ATP; adenosine-5â²-triphosphate; BiPN; bortezomib-induced peripheral neuropathy; CiPN; chemotherapy-induced
Keywords: MDM2; Polycyclic spiro-fused carbocyclicoxindoles; Antiproliferative activity; p53 inducer; MDM2;
Keywords: MDM2; ALK; anaplastic lymphoma receptor tyrosine kinase; ABCB1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; APE1; apurinic/apyimidinic endonuclease 1; AKT; v-akt murine thymoma viral oncogene; BER; base excision repair; BRCA1; breast cancer 1; BRCA2
Keywords: MDM2; Phyllodes tumor; Lipophyllodes; Immunohistochemistry; MDM2
Keywords: MDM2; BAK; BCL-2 antagonist killer; BAX; BCL-2 associated X protein; CDK1; cyclin dependent kinase 1; CLDN-6; claudin-6; CM; cardiomyocyte; CPE; Clostridium perfringens endotoxin; GPX2; glutathione peroxidase-2; GSH; glutathione; GSR; glutathione reductase; GSS
Keywords: MDM2; Sarcoma; Liposarcoma; Myxoid liposarcoma; Pleomorphic liposarcoma; CDK4; MDM2; FUS-CHOP; Trabectedin;
Keywords: MDM2; cardiomyopathy; catecholamine; gene therapy; heart failure; AAV; adeno-associated virus; AC; adenylyl cyclase; AC6mut; AC6 mutant, contains an amino acid substitution that reduces its catalytic activity; Ad5; adenovirus-5; AKAP; A-kinase-anchoring protein
Keywords: MDM2; Drp1; Dynamin-related protein1; GSK3β; Glucose synthase kinase 3 beta; CDK5; Cyclin dependent kinase 5; miRNA; micro ribonucleic acid; NMDAR; N-methyl-D-aspartate receptor; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; AD; Alzhei
Keywords: MDM2; Kidney; Stem cells; Regenerative medicine; Bcl2; B-cell lymphoma 2; CD10; neprilysin; CD15; 3-fucosyl-N-acetyl-lactosamine; CD133; prominin 1; CKD; chronic kidney disease; CK7; cytokeratin 7; CK8-18; cytokeratin 8-18; EMA (MUC1); anti-endomysial (mucin 1)
Keywords: MDM2; NAD+; nicotinamide adenine dinucleotide; SIRT; sirtuin; PARP; poly(ADP-ribose) polymerase; OHCs; outer hair cells; ROS; reactive oxygen species; NOX; NAD(P)H oxidases; TNF; tumor necrosis factor; RANTES; regulated on activation normal T-cell expressed and
Keywords: MDM2; α-TOS; α-tocopheryl succinate; BAP1; BRCA1 associated protein-1; BRCA1; breast cancer susceptibility gene 1; CDK4; cyclin-dependent kinase 4; CEA; carcinoembryonic antigen; CSC(s); cancer stem(-like) cell(s); CTGF; connective tissue growth factor (CCN2)
Keywords: MDM2; Decidual cells; MIF; Apoptosis; AKT signaling pathway; Mdm2; Cell survival
Keywords: MDM2; Ultraviolet B; Keratinocyte stem cells; p53; MDM2; Vanillin;
Keywords: MDM2; AEC; alveolar epithelial cell; AT2; alveolar epithelial type II; AM; alveolar macrophage; ARE; antioxidant response element; BALF; bronchoalveolar lavage fluid; JNK; c-Jun N-terminal kinase; EGFR; epidermal growth factor receptor; ECM; extracellular matri
Keywords: MDM2; MDM2; Rheumatoid arthritis; FLS; MAPK; NF-κB
Keywords: MDM2; MDM2; CDK4; amplification; lipoma; liposarcoma
Characterization, functional and signaling elucidation of pigeon (Columba livia) interferon-α: Knockdown p53 negatively modulates antiviral response
Keywords: MDM2; Columba livia interferon-α; Antiviral activity; p53; Autophagy; Apoptosis; Mdm2;
Isolation of a peptide containing d-amino acid residues that inhibits the α-helix-mediated p53-MDM2 interaction from a one-bead one-compound library
Keywords: MDM2; d-Amino acids; Left-handed α-helix; PPI inhibitors; MDM2; P53; One-bead one-compound; α,α-Disubstituted amino acids;
Strategies of biochemical adaptation for hibernation in a South American marsupial, Dromiciops gliroides: 3. Activation of pro-survival response pathways
Keywords: MDM2; ATR; ataxia telangiectasia and Rad3 related; Chk; checkpoint kinase; HSP; heat shock protein; H2A.X; histone 2A member X; MDM2; mouse double minute 2; Monito del monte; Hibernation; Metabolic rate depression; Stress response; Cell cycle regulation; Heat s
Autoubiquitination of feline E3 ubiquitin ligase BCA2
Keywords: MDM2; BCA2; breast cancer associated gene 2; RNF115; ring finger protein 115; BZF; BCA2 zinc finger; Mdm2; mouse double minute 2; BRCA1; breast cancer 1; FMC; feline mammary carcinoma; WHO; World Health Organization; ATCC; American Type Culture Collection; BCIP
Osteosarcoma arising in fibrous dysplasia, confirmed by mutational analysis of GNAS gene
Keywords: MDM2; FD; Fibrous dysplasia; GNAS; Guanine nucleotide-binding protein/α-subunit; MDM2; Mouse double minute 2 homolog; Fibrous dysplasia; Osteosarcoma; GNAS gene;
Survivin is critically involved in VEGFR2 signaling-mediated esophageal cancer cell survival
Keywords: MDM2; Survivin; VEGFR2; AKT1; MDM2; Esophageal cancer;
DGKζ ablation engenders upregulation of p53 level in the spleen upon whole-body ionizing radiation
Keywords: MDM2; Diacylglycerol kinase ζ; Ionizing radiation; p53; Mdm2; Spleen; Apoptosis;
Role of Forkhead Box O (FOXO) transcription factor in aging and diseases
Keywords: MDM2; FOXO; Forkhead box O; DBD; DNA-binding domain; NLS; Nuclear localization sequence; NES; Nuclear export sequence; IRE; Insulin-responsive element; ARDs; Age-related diseases; RTK; Receptor tyrosine kinase; PI3K; Phosphoinositide 3kinase; SGK; Serum and glu
Dysregulation and restoration of homeostatic network plasticity in fragile X syndrome mice
Keywords: MDM2; Fmr1; FXS; p53; Mdm2; Neural network; Plasticity;
Ubiquitination and SUMOylation in the chronic inflammatory tumor microenvironment
Keywords: MDM2; Inflammation-associated cancer; Ubiquitin-proteasome system (UPS); Small ubiquitin-like modifier (SUMO); Tumor microenvironment; Cytokine profile; Transcription factors; 15d-PGJ2; 15-Deoxy-Delta-12,14-prostaglandin J2; AR; androgen receptor; Ala; alanine;
The beneficial effects of Zn on Akt-mediated insulin and cell survival signaling pathways in diabetes
Keywords: MDM2; Akt2-KO; Akt2 gene deletion; CHO; Chinese hamster ovary; DM; diabetes mellitus; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ER; endoplasmic reticulum; GLUT4; glucose transporter type-4; GS; glycogen synthase; GSK-3; glycogen synt
Global gene expression analysis of knockdown Triosephosphate isomerase (TPI) gene in human gastric cancer cell line MGC-803
Keywords: MDM2; TPI; triosephosphate isomerase; GC; gastric cancer; DEGs; differentially expressed genes; PPI; protein-protein interaction; G3P; glyceraldehyde 3-phosphate; DHAP; dihydroxyacetone phosphate; RT-qPCR; reverse transcription-quantitative polymerase chain rea
Long noncoding RNA MEG3 inhibits proliferation of chronic myeloid leukemia cells by sponging microRNA21
Keywords: MDM2; CML; chronic myeloid leukemia; BSP; bisulfite sequencing PCR; RT-qPCR; real-time quantitative polymerase chain reaction; WB; Western blotting; FCM; flow cytometry; Chronic myeloid leukemia blast crisis; Methylation; Tyrosine kinase inhibitor; MMP-2; MDM2;
Part A: Temporal and dose-dependent transcriptional responses in the liver of fathead minnows following short term exposure to the polycyclic aromatic hydrocarbon phenanthrene
Keywords: MDM2; SREBF1; sterol regulatory element binding transcription factor 1; FASN; fatty acid synthase; HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12; ACACA; acetyl-CoA carboxylase alpha; CYB5A; cytochrome b5 type A (microsomal); SLC27A4; solute carrier family
Natural products targeting the p53-MDM2 pathway and mutant p53: Recent advances and implications in cancer medicine
Keywords: MDM2; MDM2; Natural products; Oncogene; p53; Tumor suppressor;
Promising new therapeutic targets for regulation of inflammation and immunity: RING-type E3 ubiquitin ligases
Keywords: MDM2; ALS; amyotrophiclateral sclerosis; AP-1; activator protein 1; APC; antigen-presenting cell; APC/C; anaphase promoting complex/cyclosome; CLR; C-type lectin receptor; CRL; Cullin RING ligase; ERK; extracellular signalregulated kinase; FANC; Fanconi anemia
Overexpression of GRIM-19 accelerates radiation-induced osteosarcoma cells apoptosis by p53 stabilization
Keywords: MDM2; Osteosarcoma; Radiation; GRIM-19; MDM2; p53; Apoptosis;
Epithelial mesenchymal transition Transcription Factor (TF): The structure, function and microRNA feedback loop
Keywords: MDM2; SNAIL; Snail family transcriptional repressor; ZEB; Zinc finger E-box binding homeobox; BMP1; Bone Morphogenetic protein1; TWIST; twist family bHLH transcription factor 1; GSC; goosecoid hemeobox; TGF-β; transforming growth factor beta; NPC; nasopharynge
Proteomic investigating the cooperative lethal effect of EGFR and MDM2 inhibitors on ovarian carcinoma
Keywords: MDM2; EGFR; MDM2; DIGE; Proteomics;
Ubiquitination/sumoylation: An alternative pathway to modify gene regulation directed by xenosensors
Keywords: MDM2; Epigenetic regulation; Post-translational modifications; Nuclear receptors; Xenobiotics metabolism; AHR; aryl hydrocarbon receptor; AHRR; aryl hydrocarbon receptor repressor; ARNT; aryl hydrocarbon receptor nuclear translocator; CAR; constitutive androsta
PKM2, a potential target for regulating cancer
Keywords: MDM2; PK; pyruvate kinase; HCC; hepatocellular carcinoma; FBP; fructose 1,6-bisphosphate; SAICAR; Succinyl-5-aminoimidazole-4-carboxamide-1-ribose-50-phosphate; hnRNPs; heterogeneous nuclear ribonucleoproteins; PTB; polypyrimidine tract-binding protein; NEK2; n
Solubility changes of promyelocytic leukemia (PML) and SUMO monomers and dynamics of PML nuclear body proteins in arsenite-treated cells
Keywords: MDM2; PML; Arsenic; Solubility; SUMOylation; DAXX; MDM2;