مقالات ISI (ترجمه نشده)
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Determination of a new designer drug, N-hydroxy-3,4-methylenedioxymethamphetamine and its metabolites in rats using ultra-performance liquid chromatography–tandem mass spectrometry
Keywords: N-OH MDMA; MDMA; MDA; Rats; Biological samples; UPLC–MS/MS
MDMA (ecstasy) delays pubertal development and alters sperm quality after developmental exposure in the rat
Keywords: MDMA; Male fertility; Developmental and behavioural toxicity; Sexual maturation; Sperm; Rat
Identification of post-generation effect of 3,4-methylenedioxymethamphetamine on the mouse brain by large-scale gene expression analysis
Keywords: MDMA; Neurotoxicity; Cerebral cortex; Gene expression; Offspring
MDMA administration decreases serotonin but not N-acetylaspartate in the rat brain
Keywords: Magnetic resonance spectroscopy; MDMA; Neurotoxicity; Glutamate; Hippocampus; Rat
Effects of MDMA (“ecstasy”) during adolescence on place conditioning and hippocampal neurogenesis
Keywords: Adolescent; MDMA; Conditioned place preference; Hippocampus; Proliferation; Neurogenesis; Flow cytometry; Development
Deaths involving serotonergic drugs
Keywords: Fatalities; Tramadol; Venlafaxine; SSRI; MDMA; Serotonin toxicity
Neurodegeneration, Neuroprotection, and Disease-Oriented NeuroscienceResearch PaperGenetic inactivation of Pleiotrophin triggers amphetamine-induced cell loss in the substantia nigra and enhances amphetamine neurotoxicity in the striatum
Keywords: neurotoxicity; methamphetamine; MDMA; RPTPβ/ζ; ERK1/2; Fyn; DA; dopamine; DAT; dopamine transporter; ERK1/2; extracellular-signal regulated kinase 1/2; ERK1; p44 ERK; ERK2; p42 ERK; GFAP; glial-fibrillary acidic protein; MDMA; 3,4-methylenedioxymethamph
Acute MDMA administration alters the distribution and circadian rhythm of wheel running activity in the rat
Keywords: MDMA; Activity; Sleep; Serotonin; Activity rhythm; Rat
Is ecstasy a drug of dependence?
Keywords: Dependence; MDMA; Ecstasy; Amphetamines; Nosology
Acute SSRI-induced anxiogenic and brain metabolic effects are attenuated 6 months after initial MDMA-induced depletion
Keywords: Serotonin; SSRI antidepressant; Anxiety; MDMA; Functional imaging; Social interaction; LCMRglu
GC–IRD methods for the identification of some tertiary amines related to MDMA
Keywords: MDMA; 2-Dimethylamino-1-(methoxyphenyl)ethanone; N,N-dimethyl-2-(methoxymethylphenyl)ethanamine; N,N-dimethyl-2-(2,3- and 3,4-methylenedioxyphenyl)ethanamine; Regioisomers; Isobaric substances; GC–IRD
Affinity of aporphines for the human 5-HT2A receptor: Insights from homology modeling and molecular docking studies
Keywords: Nantenine; Aporphine; Serotonin; MDMA; 5-HT2A; 5-HT; 5-hydroxytryptamine, serotonin; AcOH; acetic acid; Boc; tert-butoxycarbonyl; BLAST; Basic Local Alignment Search Tool; BRho; bovine rhodopsin; CDI; 1,1â²-carbonyldiimidazole; D; aspartic acid; DCM; dic
MDMA causes a redistribution of serotonin transporter from the cell surface to the intracellular compartment by a mechanism independent of phospho-p38-mitogen activated protein kinase activation
Keywords: ecstasy; SERT trafficking; MDMA; p38 MAPK; β-PMA; β-phorbol 12-myristate 13-acetate; FBS; fetal bovine serum; GFAP; glial fibrillary acidic protein; GFP-hSERT; green fluorescent protein-tagged human serotonin transporter; HEK; human embryonic kidney cel
Role of serotonin transporter inhibition in the regulation of tryptophan hydroxylase in brainstem raphe nuclei: time course and regional specificity
Keywords: selective serotonin reuptake inhibitor; serotonin transporter; dorsal raphe nucleus; median raphe nucleus; raphe magnus nucleus; caudal linear nucleus; ANOVA; analysis of variance; APTEX; 3-aminopropyltrietoxysilane; BH4; (6R)-5,6,7,8-tetrahydrobiopterin;
Electrophysiological and structural alterations in striatum associated with behavioral sensitization to (±)3,4-methylenedioxymethamphetamine (ecstasy) in rats: role of drug context
Keywords: dendritic spines; electrophysiology; MDMA; morphology; striatum; sensitizationAMPH, amphetamine; ANOVA, analysis of variance; DA, dopamine; MDMA, 3,4-methylenedioxymethamphetamine; NAc, nucleus accumbens; NOSENS, group of animals that did not express sens
A fatal case of myocardial damage due to misuse of the “designer drug” MDMA
Keywords: MDMA; Myocardial damage; Myoglobinuria
Simultaneous liquid chromatographic-electrospray ionization mass spectrometric quantification of 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) and its metabolites 3,4-dihydroxymethamphetamine, 4-hydroxy-3-methoxymethamphetamine and 3,4-methylenedioxya
Keywords: MDMA; Metabolites; LC–ESI-MS; Human plasma; Validation; Acidic hydrolysis
Effects of chronic intracerebroventricular 3,4-methylenedioxy-N-methamphetamine (MDMA) or fluoxetine on the active avoidance test in rats with or without exposure to mild chronic stress
Keywords: MDMA; Fluoxetine; Active avoidance; Serotonin; Mild chronic stress; Rats
Long-term neurobiological consequences of ecstasy: A role for pre-existing trait-like differences in brain monoaminergic functioning?
Keywords: 3,4-Methylenedioxymethamphetamine; MDMA; Serotonin; Dopamine; SAL and LAL mice; Brain; Personality; Coping style; 5-HT; DA
MDMA reinstates cocaine-seeking behaviour in mice
Keywords: MDMA;; Cocaine;; Drug-seeking;; Relapse;; d-amphetamine;; Reinstatement
Chronic exposure to MDMA (ecstasy) increases DNA damage in sperm and alters testes histopathology in male rats
Keywords: Ecstasy; MDMA; 3,4-Methylenedioxymethamphetamine; Rat; Male fertility; Chronic administration
Effect of 8-hydroxy-2-(N,N-di-n-propylamino)tetralin and MDMA on the discriminative stimulus effects of the classical hallucinogen DOM in rats
Keywords: DOM; MDMA; (±)8-OH DPAT; R(+)8-OH DPAT; S(â)8-OH DPAT; NAN-190; Methylenedioxymethamphetamine; Hallucinogens; Drug discrimination;
The high prevalence of substance use disorders among recent MDMA users compared with other drug users: Implications for intervention
Keywords: Alcohol use disorder; Ecstasy; Marijuana use disorder; MDMA; Substance use disorder
Methylenedioxymethamphetamine (MDMA)-related fatalities in Australia: Demographics, circumstances, toxicology and major organ pathology
Keywords: MDMA; Ecstasy; Fatalities; Death; Cardiovascular; Pathology
MDMA (ecstasy) modulates locomotor and prefrontal cortex sensory evoked activity
Keywords: MDMA; Rat; Behavior; Sensory evoked potential
Association of MDMA/ecstasy and other substance use with self-reported sexually transmitted diseases among college-aged adults: A national study
Keywords: Alcohol use; College students; Epidemiology; MDMA; Sexually transmitted diseases
The effect of Ecstasy on memory is moderated by a functional polymorphism in the cathechol-O-methyltransferase (COMT) gene
Keywords: 3,4-methylenedioxymethamphetamine; MDMA; Catechol-O-methyltransferase; Memory; Neuropsychology
Sexual Dysfunction in Men Who Abuse Illicit Drugs: A Preliminary Report
Keywords: Illicit Drug; Sexual Dysfunction; Heroin; Amphetamine; MDMA;
Long-term behavioral consequences of prenatal MDMA exposure
Keywords: MDMA; Prenatal; Attention; Spatial learning; Self-administration; Open field; Morris water maze; Progressive ratio responding; Amphetamine challenge; Radial arm maze; Hyperthermia; Body composition
Drogas de sÃntesis: novedades
Keywords: Drogas de sÃntesis; MDMA; Metanfetamina; Research chemicals;
Acetyl-l-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain
Keywords: ecstasy; 5-HT; oxidative stress; neurodegeneration; mitochondrial DNA; ALC; acetyl-l-carnitine; ANOVA; analysis of variance; bp; base pairs; BSA; bovine serum albumin; CoA; acetyl-coenzyme A; COXI; cytochrome c oxidase; DNPH; 2,4-dinitrophenylhydrazine; E
Repeated exposure to MDMA provides neuroprotection against subsequent MDMA-induced serotonin depletion in brain
Keywords: MDMA; Neuroprotection; Serotonin; Neurotoxicity;
Different likelihood ratio approaches to evaluate the strength of evidence of MDMA tablet comparisons
Keywords: Drug profiling; MDMA; Multivariate distributions; Pearson; Evidence evaluation; Likelihood ratio
Acute behavioural and neurotoxic effects of MDMA plus cocaine in adolescent mice
Keywords: Elevated plus maze; Social behaviour; Dopamine; Serotonin; Mice; MDMA; Cocaine
Hallucinogen-related disorders in a national sample of adolescents: The influence of ecstasy/MDMA use
Keywords: Alcohol use disorder; Ecstasy; MDMA; Hallucinogen use disorder; Marijuana use disorder; Subthreshold dependence
Transcriptomic configuration of mouse brain induced by adolescent exposure to 3,4-methylenedioxymethamphetamine
Keywords: MDMA; Neurotoxicity; Cerebral cortex; Molecular signature;
The distribution of γ-hydroxybutyrate-induced Fos expression in rat brain: Comparison with baclofen
Keywords: c-Fos; gamma-hydroxybutyrate; GABAB; locomotor activity; reward; sleep; ANOVA; analysis of variance; AUC; area under the curve; GBL; γ-butyrolactone; GHB; γ-hydroxybutyrate; LHB; lateral habenula; MDMA; 3,4-methylenedioxymethamphetamine; MFB; medial for
Memantine prevents MDMA-induced neurotoxicity
Keywords: MDMA; Ecstasy; Memantine; Mice; Dark Agouti rat; Neurotoxicity
Effects of the selective neurotensin antagonist SR 142948A on 3,4-methylenedioxymethamphetamine-induced behaviours in mice
Keywords: Neurotensin; MDMA; Gene expression; Behavior; Mice
Drug intelligence based on MDMA tablets data: I. Organic impurities profiling
Keywords: Drug profiling; Statistics; MDMA; Ecstasy; Organic impurities; GC/MS
Liquid chromatographic–electrospray ionization mass spectrometric assay for simultaneous determination of 3,4-methylenedioxymethamphetamine and its metabolites 3,4-methylenedioxyamphetamine, 3,4-dihydroxymethamphetamine, and 4-hydroxy-3-methoxymethampheta
Keywords: MDMA; Metabolites; LC–ESI-MS; Validation; Neurotoxicity; Brain; Rat
Drug intelligence based on MDMA tablets data: 2. Physical characteristics profiling
Keywords: Drug profiling; Intelligence; Statistics; MDMA; Ecstasy; Physical Characteristics
pH dependent efflux of methamphetamine derivatives and their reversal through human Caco-2 cell monolayers
Keywords: MDMA; MDEA; p-MA; Epinephrine; Noradrenalin; Reserpine
Risperidone attenuates and reverses hyperthermia induced by 3,4-methylenedioxymethamphetamine (MDMA) in rats
Keywords: MDMA; Dopamine; Serotonin; Microdialysis; Risperidone
Effects of priming injections of MDMA and cocaine on reinstatement of MDMA- and cocaine-seeking in rats
Keywords: MDMA; Cocaine; Self-administration; Relapse; Drug-seeking
When administered to rats in a cold environment, 3,4-methylenedioxymethamphetamine reduces brown adipose tissue thermogenesis and increases tail blood flow: Effects of pretreatment with 5-HT1A and dopamine D2 antagonists
Keywords: MDMA; thermoregulation; ambient temperatureiBAT, interscapular brown adipose tissue; MDMA, 3,4-methylenedioxymethamphetamine; SNA, sympathetic nerve activity; 8-OH-DPAT, 8-hydroxy-2(di-n-propylamino) tetralin
Behavioural and neurotoxic long-lasting effects of MDMA plus cocaine in adolescent mice
Keywords: Elevated plus maze; Locomotor activity; Social behaviour; Dopamine; Serotonin; MDMA; Cocaine; (Mouse)
Memantine prevents the cognitive impairment induced by 3,4-methylenedioxymethamphetamine in rats
Keywords: Memantine; MDMA; Ecstasy; Learning and memory; Object recognition; Morris water maze
Development of a two-step injector for GC–MS with on-column derivatization, and its application to the determination of amphetamine-type stimulants (ATS) in biological specimens
Keywords: On-column derivatization; MBTFA; Trifluoroacetylation; ATS; Methamphetamine; MDMA; GC–MS; Sample injector; Automation