Effect of MDMA (ecstasy) on activity and cocaine conditioned place preference in adult and adolescent rats
Keywords: Adolescent; Adult; MDMA; Cocaine; Locomotor activity
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MDMA-like behavioral effects of N-substituted piperazines in the mouse
Keywords: MDMA; Drug discrimination; Head twitch response; Locomotor activity
Neurochemical and behavioral consequences of striatal injection of 5,7-dihydroxytryptamine
Keywords: Serotonin; Dopamine; 5,7-Dihydroxytryptamine; Nomifensine; MDMA; Ventral striatum; Neostriatum; Frontal cortex; Amygdala; Elevated plus maze; Anxiety; Avoidance; Locomotion; Ultrasonic vocalization;
MDMA (“Ecstasy”) suppresses the innate IFN-γ response in vivo: A critical role for the anti-inflammatory cytokine IL-10
Keywords: MDMA; IFN-γ; Immunosuppression; IL-10; Ecstasy; Drug abuse
Serotonin2C receptor localization in GABA neurons of the rat medial prefrontal cortex: Implications for understanding the neurobiology of addiction
Keywords: immunohistochemistry; parvalbumin; calbindin; calretinin; prelimbic prefrontal cortex; ACC; anterior cingulate cortex; DA; dopamine; DAPI; 4â²,6-diamidoino-2-phenylindole; DOI; 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane; GAD 67; glutamate decarboxylas
Neurotoxicity mechanisms of thioether ecstasy metabolites
Keywords: cortical neurons; MDMA; thioether MDMA-metabolites; NAC; neurotoxicityAc-DEVD-pNA, acetyl-Asp-Glu-Val-Asp p-nitroanilide; BSA, bovine serum albumin; DA, dopamine; DHR-123, dihydrorhodamine 123; DIV, day in vitro; GSSG, oxidized glutathione; GSH, glutathio
Are there sex differences associated with the effects of ecstasy/3,4-methylenedioxymethamphetamine (MDMA)?
Keywords: MDMA; 3; 4-methylenedioxymethamphetamine; Ecstasy; Sex differences; Acute effects; Subacute effects; Long-term effects; Menstrual cycle; Gonadal hormones; Pharmacokinetics; Pharmacodynamics; Metabolism; Serotonin; Dopamine
Increased risk of “club” drug use among gay and bisexual high school students in British Columbia
Keywords: Adolescent; Ecstasy; Gamma hydroxybutyrate; Homosexual; Ketamine; Methamphetamine; MDMA
A demonstration of the use of ultra-performance liquid chromatography–mass spectrometry [UPLC/MS] in the determination of amphetamine-type substances and ketamine for forensic and toxicological analysis
Keywords: Ultra-performance liquid chromatography; UPLC; Amphetamine-type substances; Mass spectrometry; Methamphetamine; MDMA; Ketamine
Interactions between 3,4-methylenedioxymethamphetamine and Ï1 receptors
Keywords: Ï Receptor; MDMA; BD1063; Locomotor;
Differential effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) on BDNF mRNA expression in rat frontal cortex and hippocampus
Keywords: BDNF; MDMA; Serotonin; CREB
Party people: Personality and MDMA use of house party visitors
Keywords: MDMA; Ecstasy; Drug use; Personality; Big Five; Five Factor Model
The study of metabolite-to-parent drug ratios of methamphetamine and methylenedioxymethamphetamine in hair
Keywords: Metabolite-to-parent drug ratios; Methamphetamine; MDMA; Hair analysis
Hyperthermia induced by 3,4-methylenedioxymethamphetamine in unrestrained rhesus monkeys
Keywords: MDMA; Macaca mulatta; Circadian; Thermoregulation; Serotonin
Binge administration of 3,4-methylenedioxymethamphetamine (“ecstasy”) impairs the survival of neural precursors in adult rat dentate gyrus
Keywords: Ecstasy; MDMA; Adult neurogenesis; Hippocampus; 5′-Bromo-2-deoxyuridine; DoublecortinBrdU, 5’-bromo-2-deoxyuridine; DCX, doublecortin; DG, dentate gyrus; 5,7-DHT, 5,7-dihydroxytryptamine; MDMA, 3,4-methylenedioxymethamphetamine; 5-HT, serotonin; HHA, 3,4-
MDMA administration to pregnant Sprague–Dawley rats results in its passage to the fetal compartment
Keywords: 3,4-methylenedeoxymethamphetamine; MDMA; Prenatal; Pharmacokinetics; HPLC; 3,4-methylenedioxyamphetamine; MDA
Characteristics and trends of 3,4-methylenedioxymethamphetamine (MDMA) tablets found in Taiwan from 2002 to February 2005
Keywords: GC–MS; MDMA; Methamphetamine; MDEA; Amphetamine; MDA
Binding of bufuralol, dextromethorphan, and 3,4-methylenedioxymethylamphetamine to wild-type and F120A mutant cytochrome P450 2D6 studied by resonance Raman spectroscopy
Keywords: Cytochrome P450 2D6; CYP2D6; Resonance Raman; MDMA; Dextromethorphan; Bufuralol; Substrate mobility
3,4-Methylenedioxymethamphetamine in Adult Rats Produces Deficits in Path Integration and Spatial Reference Memory
Keywords: MDMA; Morris water maze; Cincinnati water maze; sequential learning; spatial learning
The neurotoxicity of amphetamines: Bridging drugs of abuse and neurodegenerative disorders
Keywords: Amphetamines; β-Arrestin; Lewy body; MDMA; Methamphetamine; Neuronal inclusions; Parkinson's disease; Neurodegenerative disorders; α-Synuclein; Ubiquitin–proteasome system
Pharmacological content of tablets sold as “ecstasy”: Results from an online testing service
Keywords: Drug purity; Ecstasy; MDMA; Toxicology; Chemical analyses
Imaging brain activity in conscious monkeys following oral MDMA (“ecstasy”)
Keywords: MDMA; Functional MRI; Marmoset monkey
Patterns of use and harm reduction practices of ecstasy users in Australia
Keywords: Adverse effects; Ecstasy; Harm reduction; MDMA; Survey research
Neonatal 3,4-methylenedioxymethamphetamine (MDMA) exposure alters neuronal protein kinase A activity, serotonin and dopamine content, and [35S]GTPγS binding in adult rats
Keywords: MDMA; Ecstasy; Protein kinase A; Ontogeny; Serotonin; 5-HT1A receptors
Quantitative mapping shows that serotonin rather than dopamine receptor mRNA expressions are affected after repeated intermittent administration of MDMA in rat brain
Keywords: Ecstasy; MDMA; Serotonin receptor; Dopamine receptor; Drug abuse; mRNA
Analysis of transcriptional responses in the mouse dorsal striatum following acute 3,4-methylenedioxymethamphetamine (ecstasy): Identification of extracellular signal-regulated kinase-controlled genes
Keywords: MDMA; ERK; plasticity; gene expressionDA, dopamine; DMSO, dimethyl sulfoxide; ECL, enhanced chemiluminescence; ERK, extracellular signal-regulated kinase; IEG, immediate early gene; MDMA, 3,4-methylenedioxymethamphetamine; OD, optical density; pERK, phosp
Patterns and perceptions of ecstasy use among young, low-income women
Keywords: Methlenedioxy-methamphetamine; MDMA; Ecstasy; Risk factors; Low income; Women
Chronic and acute effects of 3,4-methylenedioxy-N-methylamphetamine ('ecstasy') administration on the dynorphinergic system in the rat brain
Keywords: opioids; dynorphin A; gene expression; abuse; amphetamine; CP; caudate putamen; CPP; conditioned place preference; CREB; c-AMP responsive element binding protein; DA; dopamine; DAT; dopamine transporter; DYN; dynorphin; HPA; hypothalamic-pituitary-adr
MDMA use is associated with increased spatial BOLD fMRI visual cortex activation in human MDMA users
Keywords: 3,4-Methylenedioxymethamphetamine; MDMA; Ecstasy; Neurotoxicity; Neuroimaging; Functional magnetic resonance imaging; fMRI; Serotonin
Intravenous methamphetamine self-administration in rats: Effects of intravenous or intraperitoneal MDMA co-administration
Keywords: MDMA; Ecstasy; Methamphetamine; Dopamine; Serotonin; Self-administration; Reward; Reinforcement; Progressive-ratio
Long-term ecstasy use and the management of work and relationships
Keywords: Ecstasy; MDMA; Long-term effects; Work; Relationships; Self-regulation
Chronic treatment with a serotonin2 receptor (5-HT2R) agonist modulates the behavioral and cellular response to (+)-3,4-methylenedioxymethamphetamine [(+)-MDMA]
Keywords: DOI; MDMA; Serotonin receptor; Sensitization; Hyperactivity; MK 212
Protection against MDMA-induced dopaminergic neurotoxicity in mice by methyllycaconitine: Involvement of nicotinic receptors
Keywords: MDMA; Ecstasy; α-7 Nicotinic receptor; Mice; Neurotoxicity
Caffeine promotes hyperthermia and serotonergic loss following co-administration of the substituted amphetamines, MDMA (“Ecstasy”) and MDA (“Love”)
Keywords: MDMA; Caffeine; Hyperthermia; Serotonergic loss; Neurotoxicity; Rat
Concurrent use of methamphetamine, MDMA, LSD, ketamine, GHB, and flunitrazepam among American youths
Keywords: Adolescents; GHB; Ketamine; LSD; Methamphetamine; MDMA; Rohypnol
Prevalence and correlates of current depressive symptomatology among a community sample of MDMA users in Ohio
Keywords: MDMA; Depression; Substance abuse; BDI-II; Epidemiology
Ecstasy-induced cell death in cortical neuronal cultures is serotonin 2A-receptor-dependent and potentiated under hyperthermia
Keywords: MDMA; primary cortical neuronal serum free culture; hyperthermia; apoptosis; neurotoxicity; 5-HT2A-receptorDIV, day in vitro; DOI, (±)-2,5-dimethoxy-4-iodoamphetamine hydrochloride; LDH, lactate dehydrogenase; L-NNA, N ω-nitro-l-arginine; MDMA, 3,4-methyl
Cognitive determinants of MDMA use among college students in Southern Taiwan
Keywords: MDMA; College students; Outcome expectancy; MDMA refusing self-efficacy; Social influence
Incidence and patterns of polydrug use and craving for ecstasy in regular ecstasy users: An ecological momentary assessment study
Keywords: MDMA; Ecstasy; Drug abuse; Polysubstance abuse; Ecological momentary assessment
Organic impurity profiling of 3,4-methylenedioxymethamphetamine (MDMA) tablets seized in the Netherlands
Keywords: MDMA; profiling; comparison; gas chromatography mass spectrometry;
Ecstasy-deadly risk even outside rave parties
Keywords: MDMA; Ecstasy; Fatality; Poisoning;
Methylenedioxymethamphetamine (ecstasy)-related hyperthermia
Keywords: methylenedioxymethamphetamine; MDMA; hyperthermia; substance abuse;
Our experiences with fatal ecstasy abuse (two case reports)
Keywords: MDMA; Insulin; Intoxication; Suicide; Accidents;
The prevalence of MDMA/MDA in both hair and urine in drug users
Keywords: Designer drugs; MDMA; MDA; Hair analysis;
Determination of MDMA, MDA, MDEA and MBDB in oral fluid using high performance liquid chromatography with native fluorescence detection
Keywords: MDMA; MDA; MDEA; MBDB; Oral fluid; HPLC; Fluorescence;
A comparison of the reinforcing efficacy of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) with cocaine in rhesus monkeys
Keywords: Cocaine; MDMA; Drug abuse; Reinforcing efficacy; Rhesus monkey;
Psychostimulants and monoamine transporters: upsetting the balance
Keywords: ADHD; attention deficit hyperactivity disorder; AMPH; amphetamine; CPP; conditioned place preference; DAT; dopamine transporter; KO; knockout; METH; methamphetamine; MDMA; 3,4-methylenedioxymethamphetamine; NET; norepinephrine transporter; PKC; protein ki
Memory performance in polyvalent MDMA (ecstasy) users who continue or discontinue MDMA use
Keywords: Ecstasy; MDMA; Cognition; Memory; Neurotoxicity; Serotonin;
Unhealthy weight control behaviors and MDMA (Ecstasy) use among adolescent females
Keywords: Adolescent females; Ecstasy; MDMA; N-Methyl-3,4-methylenedioxyamphetamine; Eating disorders; Weight control behaviors;
Pizotyline effectively attenuates the stimulus effects of N-Methyl-3,4-methylenedioxyamphetamine (MDMA)
Keywords: Designer drugs; Clozapine; Cyproheptadine; Pizotyline; Pizotifen; BC-105; Stimulus antagonism; Radioligand binding; MDMA; PMMA;