دانلود مقالات ISI درباره Mdr1 + ترجمه فارسی

H19 mediates methotrexate resistance in colorectal cancer through activating Wnt/β-catenin pathway

Keywords: CRC; colorectal cancer; DHFR; dihydrofolate reductase; DMEM; Dulbecco's modified Eagle's medium; lncRNAs; long or large noncoding RNAs; HT-29-R; MTX-resistant colorectal cell line HT-29; MDR1; multi-drug resistance 1; MTT; 3-(4,5-Dimethylthiazol-2-yl)-2,5

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Targeted inhibition of HDAC8 increases the doxorubicin sensitivity of neuroblastoma cells via up regulation of miR-137

Keywords: HDAC8; Neuroblastoma; Dox; MiR-137; MDR1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

5′-Triphosphate siRNA targeting MDR1 reverses multi-drug resistance and activates RIG-I-induced immune-stimulatory and apoptotic effects against human myeloid leukaemia cells

Keywords: siRNA; RIG-I; DDX58; MDR1; CXCL10; leukaemia; apoptosis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

P-Glycoprotein in skin contributes to transdermal absorption of topical corticosteroids

Keywords: P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; SC; stratum corneum; ABC; ATP-binding cassette; MDR1; multidrug resistance 1; MDCK II; Madin-Darby canine kidney II; BL; basal; AP; apical; ER; efflux ratio; Papp; apparent permeability coeffic

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Anticancer activity of baicalein and luteolin studied in colorectal adenocarcinoma LoVo cells and in drug-resistant LoVo/Dx cells

Keywords: MDR; multidrug resistance; SRB; sulforhodamine B; siRNA; short interfering RNA; RNAi; RNA interference; Mdr1; multidrug resistance protein 1; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; MRP1; multidrug resistance associated protein 1; β

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Non-heat shock responsive roles of HSF1 in Candida albicans are essential under iron deprivation and drug defense

Keywords: MDR1; Multi drug resistance-1; BPS; Bathophenanthroline disulfonate; (DOX; Doxycycline; Heat shock factor 1; MDR; Iron homeostasis; Mitochondrial integrity; Filamentation; C. albicans;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

On the mechanism of substrate/non-substrate recognition by P-glycoprotein

Keywords: P-glycoprotein; P-gp; MDR1; ABCB1; Docking; Substrates;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Astrocyte elevated gene-1 (AEG-1) and the A(E)Ging HIV/AIDS-HAND

Keywords: Astrocytes; Aging; HIV-associated neurocognitive disorders; Neuroinflammation; ER/Nucleolar/Oxidative stress; Excitotoxicity; Aβ; amyloid beta; AEG-1; astrocyte elevated gene-1; AD; Alzheimer's disease; AIDS; acquired immune deficiency syndrome; ARE; a

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Rifampicin-induced injury in HepG2 cells is alleviated by TUDCA via increasing bile acid transporters expression and enhancing the Nrf2-mediated adaptive response

Keywords: RFP; rifampicin; TUDCA; tauroursodeoxycholic acid; Nrf2; nuclear factor erythroid 2-related factor; DILI; drug-induced liver injury; ALF; acute liver failure; TB; tuberculosis; INH; isoniazid; GSH; glutathione; BAs; bile acids; ER; endoplasmic reticulum;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Association of MDR1, CYP2D6, and CYP2C19 gene polymorphisms with prophylactic migraine treatment response

Keywords: Migraine; Prophylactic therapy response; MDR1; Polymorphism;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Morphometric analysis of the cerebral expression of ATP-binding cassette transporter protein ABCB1 in chronic schizophrenia: Circumscribed deficits in the habenula

Keywords: ABCB1; ATP-binding cassette, subfamily B member 1; ANCOVA; analysis of covariance; CD-243; cluster of differentiation 243; CG; cingulate gyrus; CNS; central nervous system; DG; dentate gyrus; DSM-IV; Diagnostic and Statistical Manual of Mental Disorders (

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of acquired-resistance hepatocellular carcinoma cell growth by combining sorafenib with phosphoinositide 3-kinase and rat sarcoma inhibitor

Keywords: Sorafenib; Hepatocellular carcinoma; Drug resistance; ERK; PI3K; MDR1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

P-gp, MRP2 and OAT1/OAT3 mediate the drug-drug interaction between resveratrol and methotrexate

Keywords: Res; resveratrol; MTX; methotrexate; P-gp; P-glycoprotein; MRP2; multidrug resistance-associated protein 2; MDR1; multidrug resistance 1; OATs; organic anion transporters; DDIs; drug-drug interactions; Papp; apparent permeability coefficients; ER; Efflux

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Integrated biomarkers induced by chlorpyrifos in two different life stages of zebrafish (Danio rerio) for environmental risk assessment

Keywords: Zebrafish; Chlorpyrifos; CYP3A; MDR1; Biomarkers; MALDI-TOF MS/MS

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Cancer development, chemoresistance, epithelial to mesenchymal transition and stem cells: A snapshot of IL-6 mediated involvement

Keywords: Cytokine; IL-6; Cancer stem cell; Chemoresistance and EMT; MAPK; mitogen-activated protein kinases; STAT3; signal transducer and activator of transcription 3; gp130; glycoprotein 130; C/EBP; CCAAT/enhancer-binding protein; JAK; Janus kinase; PI3K; phospho

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Quantitative targeted absolute proteomics for 28 human transporters in plasma membrane of Caco-2 cell monolayer cultured for 2, 3, and 4 weeks

Keywords: QTAP; Protein expression level; Caco-2; MDR1; BCRP; PEPT1; OSTα/β; Different culture period; LC-MS/MS; SRM/MRM analysisABC, ATP-binding cassette; LC-MS/MS, liquid chromatography–tandem mass spectrometry; QTAP, quantitative targeted absolute proteomic(s);

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Pancreatic cancer cells express CD44 variant 9 and multidrug resistance protein 1 during mitosis

Keywords: Pancreatic cancer; CD44; MDR1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

MDR1 C3435T polymorphism and childhood acute lymphoblastic leukemia susceptibility: An updated meta-analysis

Keywords: MDR1; Polymorphism; Childhood acute lymphoblastic leukemia risk; Meta-analysis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

NOX1 mediates chemoresistance via HIF1α/MDR1 pathway in gallbladder cancer

Keywords: Gallbladder cancer; NOX1; HIF1α; MDR1; Chemoresistance; Cisplatin;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of prognostic subgroups among acute myeloid leukemia patients with intermediate risk cytogenetics using a flow-cytometry-based assessment of ABC-transporter function

Keywords: Allo-SCT; allogeneic stem cell transplantation; AML; acute myeloid leukemia; BCRP; Breast Cancer Resistance Protein; BM; bone marrow; CEBPA; CCAAT/enhancer binding protein alpha; CR; complete remission; DFS; disease free survival; DNR; daunorubicin; FLT3

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Overexpression of EPS8 is associated with poor prognosis in patients with acute lymphoblastic leukemia

Keywords: EPS8; MDR1; WT1; Acute lymphoblastic leukemia; mRNA expression; Minimal residual disease;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Homology modelling and molecular docking of MDR1 with chemotherapeutic agents in non-small cell lung cancer

Keywords: MDR1; Homology modelling; Binding affinity; Chemotherapeutics; Non-small cell lung cancer

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

P-glycoprotein inhibition by the agricultural pesticide propiconazole and its hydroxylated metabolites: Implications for pesticide-drug interactions

Keywords: ABC; ATP-binding cassette; ER; endoplasmic reticulum; U.S. FDA; U.S. Food and Drug Administration; NMQ; N-methyl quinidine; P-gp; P-glycoprotein; P-gp; MDR1; Conazoles; Propiconazole; Chemosensitization; ABC transporters;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting glucosylceramide synthase induction of cell surface globotriaosylceramide (Gb3) in acquired cisplatin-resistance of lung cancer and malignant pleural mesothelioma cells

Keywords: Gb3; Globotriaosylceramide; GCS; Glucosylceramide synthase; GSL; Glycosphingolipid; MDR1; Multidrug resistance 1/P-glycoprotein; MPM; Malignant pleural mesothelioma (MPM); MRP1; Multidrug resistance-associated protein 1; NSCLC; Non-small cell lung cancer;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Cytotoxicity of medicinal plants of the West-Canadian Gwich׳in Native Americans towards sensitive and multidrug-resistant cancer cells

Keywords: MDR; multidrug resistance; ABC; ATP-binding cassette; MRP1; multidrug resistance related protein 1; BCRP; breast cancer resistance protein; MDR1; multidrug resistance gene 1 (P-glycoprotein); ABC transporter; Cancer; First nations; Multidrug resistance; P

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Expression of the multidrug transporter P-glycoprotein is inversely related to that of apoptosis-associated endogenous TRAIL

Keywords: ABCB1; MDR1; TRAIL; apoptosis; TET-Off; multidrug resistance; TNFSF10

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Enhancement effect of resveratrol on the intestinal absorption of bestatin by regulating PEPT1, MDR1 and MRP2 in vivo and in vitro

Keywords: Res; resveratrol; Mdr1; multidrug resistance 1; Pept1; peptide transporter 1; Mrp2; multidrug resistance-associated protein 2; IGF-1R; insulin-like growth factor 1 receptor; ERK; extracellular signal-regulated kinase; AKT; protein kinase B; ABC; ATP-bindi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Temozolomide competes for P-glycoprotein and contributes to chemoresistance in glioblastoma cells

Keywords: Glioblastoma; MDR1; P-gp; Temozolomide; Chemoresistance;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

Low MDR1 and BAALC expression identifies a new subgroup of intermediate cytogenetic risk acute myeloid leukemia with a favorable outcome

Keywords: BAALC; MDR1; AML; Cytogenetic risk

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Epigenetic regulation of the ABCB1 gene in drug-sensitive and drug-resistant lymphoid tumour cell lines obtained from canine patients

Keywords: DNA methylation; Dog; Histone H3 acetylation; MDR1; Multidrug resistance;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Comparison of MDCK-MDR1 and Caco-2 cell based permeability assays for anti-malarial drug screening and drug investigations

Keywords: MDCK; Madin-Darby canine kidney; MDR1; multi-drug resistance gene 1; Caco-2; colorectal adenocarcinoma; P-gp; P-glycoprotein; Papp; permeability coefficient; PAPMA; parallel artificial membrane permeability assay; LC-MS; liquid chromatography-mass spe

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

In vitro transport assays of rufinamide, pregabalin, and zonisamide by human P-glycoprotein

Keywords: Pgp; ABCB1; MDR1; Rufinamide; Zonisamide; Pregabalin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of dual DNA-PK MDR1 inhibitors for the potentiation of cytotoxic drug activity

Keywords: DNA-PK; MDR1; NU7441; Cancer; Multidrug resistance;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Aliskiren toxicity in juvenile rats is determined by ontogenic regulation of intestinal P-glycoprotein expression

Keywords: MDR1, multidrug-resistant protein 1; NOAEL, no observable adverse effect level; OATP, organic anion transporting polypeptide; P-gp, P-glycoprotein; PPD, postpartum dayAliskiren; Juvenile rat; Toxicity; Exposure; MDR1; OATP

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Respiratory sensitizer hexamethylene diisocyanate inhibits SOD 1 and induces ERK-dependent detoxifying and maturation pathways in dendritic-like cells

Keywords: Respiratory allergy; Mitochondria; ROS; SOD; ERK; MDR1; THP-1 dendritic cells; Free radicals;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Kinase domain inhibition of leucine rich repeat kinase 2 (LRRK2) using a [1,2,4]triazolo[4,3-b]pyridazine scaffold

Keywords: AD; Alzheimer's disease; ANK; ankyrin repeat domain; ARM; armadillo repeat domain; AUC; area under the curve; BA; brain availability; BBB; blood brain barrier; BCRP; breast cancer related protein; BI; brain impairment; CSD; Cambridge Structural Database

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

A novel MDCKII in vitro model for assessing ABCG2-drug interactions and regulation of ABCG2 transport activity in the caprine mammary gland by environmental pollutants and pesticides

Keywords: AhR; aryl hydrocarbon receptor; ABZSO; albendazole sulfoxide; ARNT; aryl hydrocarbon receptor nuclear translocator; CALUX assay; chemical activated luciferase gene expression assay; CYP1A1; cytochrome P450 1A1; DRE; dioxin response element; MDCKII cells;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity

Keywords: MRP2; multidrug resistance-associated protein 2; MDR1; multidrug resistance protein 1; BCRP; breast cancer resistance protein; EE; ethynylestradiol; GNT; genistein; ER; estrogen receptor; AP-1; activating protein-1; Sp1; specificity protein-1; PQ; paraqua

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Trps1 is associated with the multidrug resistance of osteosarcoma by regulating MDR1 gene expression

Keywords: TRPS1; Osteosarcoma; MDR1; P-gp; Chemotherapy; CHIP; Multidrug resistance; TGFbeta-1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

ERα directly activated the MDR1 transcription to increase paclitaxel-resistance of ERα-positive breast cancer cells in vitro and in vivo

Keywords: Breast cancer; ERα; MDR1; Paclitaxel; Chemotherapy resistance;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

DJ-1 mediates the resistance of cancer cells to dihydroartemisinin through reactive oxygen species removal

Keywords: ARTs; artemisinin and its derivatives; BCRP; breast cancer resistance protein; DCF-DA; 2′,7′-dichlorodihydrofluorescein diacetate; DHA; dihydroartemisinin; DHE; dihydroethidine; 5-FU; 5-fluorouracil; GCLC; glutamate-cysteine ligase catalytic subunit

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Thiazide-like diuretic drug metolazone activates human pregnane X receptor to induce cytochrome 3A4 and multidrug-resistance protein 1

Keywords: PXR; Metolazone; Drug metabolism; CYP3A4; MDR1

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

The association of MDR1 C3435T and G2677T/A polymorphisms with plasma platelet-activating factor levels and coronary artery disease risk in Turkish population

Keywords: CAD; coronary artery disease; PAF; platelet activating factor; MDR1; multidrug-resistance 1; P-gp; P-glycoprotein; PCR; polymerase chain reaction; RFLP; restriction fragment length polymorphism; ELISA; enzyme-linked immunosorbent assay; Coronary artery di

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Silencing the EZH2 gene by RNA interference reverses the drug resistance of human hepatic multidrug-resistant cancer cells to 5-Fu

Keywords: EZH2; Hepatocellular carcinoma; Multidrug resistance; MDR1; RNA interference;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Acetaminophen Inhibits Intestinal P-Glycoprotein Transport Activity

Keywords: acetaminophen; P-glycoprotein; MDR1; intestine; digoxin; sigmoidal; drug interactions; intestinal absorption; ABC transporters; multidrug resistance;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

P-glycoprotein (Mdr1a/1b) and breast cancer resistance protein (Bcrp) decrease the uptake of hydrophobic alkyl triphenylphosphonium cations by the brain

Keywords: ABC proteins; ATP binding cassette proteins; BBB; blood-brain barrier; Bcrp; breast cancer resistance protein; CsA; cyclosporin A; IP; intra peritoneal; IV; intra venous; Mdr1; multi drug resistance 1; MitoF; 11-fluoroundecyltriphenylphosphonium mesylat

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387

Keywords: AUC; area under the plasma concentration-time curve; Cmax; maximum drug concentration in plasma; Tmax; the time after administration of a drug when the maximum plasma concentration is reached; BBB; blood-brain barrier; BCRP; breast cancer resistance p

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Doxorubicin decreases paraquat accumulation and toxicity in Caco-2 cells

Keywords: ABCB1; ATP-binding cassette sub-family B member 1; BSA; bovine serum albumin; DMEM; Dulbecco's Modified Eagle's Medium; DOX; doxorubicin; EDTA; ethylenediamine tetraacetic acid; EPQ; ethylparaquat; FBS; fetal bovine serum; GC-IT-MS; gas chromatographyâ€

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

A review of the current understanding and clinical utility of miRNAs in esophageal cancer

Keywords: miRNA/miR; MicroRNA [ribonucleic acid]; EAC; Esophageal adenocarcinoma; BE; Barrett's esophagus; LGD; Low grade dysplasia; HGD; High grade dysplasia; ESCC; Esophageal squamous cell carcinoma; NE; Normal epithelium; qRT-PCR; Quantitative reverse transcript

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Polymorphisms of MDR1, CYP2C19 and P2Y12 genes in Indian population: Effects on clopidogrel response

Keywords: Clopidogrel; CYP2C19; Gene polymorphisms; MDR1; P2Y12

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه