دانلود مقالات ISI درباره Mdr1 + ترجمه فارسی

Application of permeability‐limited physiologically-based pharmacokinetic models: Part II-prediction of p‐glycoprotein mediated drug–drug interactions with digoxin

Keywords: transporter-mediated drug–drug interactions; P-glycoprotein; ABCB1; MDR1; simulation; digoxin; pharmacokinetics; transporter

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Application of permeability-limited physiologically-based pharmacokinetic models: Part I–digoxin pharmacokinetics incorporating P-glycoprotein-mediated efflux

Keywords: P-glycoprotein; ABCB1; MDR1; simulation; digoxin; IVIVE; pharmacokinetics; transporter

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

The single nucleotide polymorphism and haplotype analysis of MDR1 in Jiangsu Han population of China

Keywords: MDR1; Haplotype frequency; Single nucleotide polymorphism(SNP);

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Polymorphisms of glutathione S-transferase μ and θ, MDR1 and VEGF genes as risk factors of bladder cancer: A case-control study

Keywords: Bladder cancer; Genetic polymorphism; GSTM1; GSTT1; MDR1; VEGF; Risk factor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

ETS1 promotes chemoresistance and invasion of paclitaxel-resistant, hormone-refractory PC3 prostate cancer cells by up-regulating MDR1 and MMP9 expression

Keywords: ETS1; E26 transformation specific sequence 1; MDR1; multi drug resistance 1; uPA; urinary type plasminogen activator; MMP; matrix metalloprotease; ECM; extra cellular matrix; TBP; TATA-binding protein; GAPDH; glyceraldehydes 3 phosphate dehydrogenase; ADT

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

ABCB1 (P-glycoprotein) reduces bacterial attachment to human gastrointestinal LS174T epithelial cells

Keywords: Inflammatory bowel disease; MDR1; E. coli; Staphylococcus aureus; Gut infections;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Blonanserin, a novel atypical antipsychotic agent not actively transported as substrate by P-glycoprotein

Keywords: AUC0-6 h; Area under the plasma concentration time curve from 0 to 6 h; B/P; Brain/Plasma; BSA; Bovine serum albumin; Cmax; Maximum drug concentration; CNS; Central nervous system; DDI; Drug-drug interaction; EPS; Extrapyramidal symptoms; FBS; Fetal

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Meta-analysis of the effect of MDR1 C3435 polymorphism on tacrolimus pharmacokinetics in renal transplant recipients

Keywords: ABCB1, ATP binding cassette subfamily B, member 1; CYP3A, cytochrome P450 3A; P-gp, P-glycoprotein; OR, odds ratio; CI, confidence intervalRenal transplantation; Tacrolimus pharmacokinetics; Polymorphism; MDR1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

High sodium butyrate levels induce MDR1 activation in colorectal cells: Impact of 15-deoxy-Δ12,14-prostaglandin J2 on the resistance to saquinavir

Keywords: P-glycoprotein; MDR1; Sodium butyrate; 15d-PGJ2; HIV; Saquinavir

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Polymorphisms in Genes That Regulate Cyclosporine Metabolism Affect Cyclosporine Blood Levels and Clinical Outcomes in Patients Who Receive Allogeneic Hematopoietic Stem Cell Transplantation

Keywords: Stem cell transplantation; Cyclosporine; CYP3A5; MDR1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

ABCB1/MDR1 contributes to the anticancer drug-resistant phenotype of IPH-926 human lobular breast cancer cells

Keywords: Breast cancer; Drug-resistance; MDR1; Lobular histology; Valspodar

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Overexpression of MDR1 and survivin, and decreased Bim expression mediate multidrug-resistance in multiple myeloma cells

Keywords: Multiple myeloma; MDR1; Survivin; Bim; Multi-drug resistance;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Maternal undernutrition reduces P-glycoprotein in guinea pig placenta and developing brain in late gestation

Keywords: Maternal undernutrition; Blood–brain barrier; P-glycoprotein; MDR1; Placenta; Guinea pig; Fetus

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Interference of Frizzled 1 (FZD1) reverses multidrug resistance in breast cancer cells through the Wnt/β-catenin pathway

Keywords: Breast cancer; Multidrug resistance; MDR1; FZD1; Wnt/β-catenin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Evaluation of intracellular trafficking and clearance from HeLa cells of doxorubicin-bound block copolymers

Keywords: DDS; drug delivery system; PEG; polyethyleneglycol; RES; reticuloenodothelial system; EPR; enhanced permeability and retention; Dox; doxorubicin; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; DLS; dynamic light scattering; AFM; atomic

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Ivermectin induces P-glycoprotein expression and function through mRNA stabilization in murine hepatocyte cell line

Keywords: ABC, ATP-binding cassette; AhR, aryl-hydrocarbon receptor; CAR, constitutive androstane receptor; IVM, ivermectin; MLs, macrocyclic lactones; P-gp, P-glycoprotein; PXR, pregnane X receptorIvermectin; Macrocyclic lactones; P-glycoprotein; Mdr1; Hepatocytes

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Potentiation of amyloid-β peptide neurotoxicity in human dental-pulp neuron-like cells by the membrane lipid peroxidation product 4-hydroxynonenal

Keywords: Aβ; amyloid-β; AD; Alzheimer's disease; DAPI; 4,6-diamidino-2-phenylindole; DPNLC; dental-pulp neuron-like cells; DPPC; dental-pulp progenitor cells; GFAP; glial fibrillary acidic protein; HHE; trans-4-hydroxy-2-hexenal; HNE; 4-hydroxynonenal; IL; inter

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Stem cells as the root of pancreatic ductal adenocarcinoma

Keywords: ABC; ATP binding cassette; ALDH1; Aldehyde dehydrogenase 1a1; Arx; Aristalless-related homeobox; EMT; Epithelial-to-mesenchymal transition; CAC; Centroacinar cells; CD; Cluster of differentiation; CDKN2A; Cyclin-dependent kinase inhibitor 2A; CSC; Cancer

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Enhancement of drug efflux activity via MDR1 protein by spheroid culture of human hepatic cancer cells

Keywords: Spheroid; Multidrug resistance; MDR1; Hepatic cancer cells; Doxorubicin; Cell-based assay system; IC50

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

The effect of smoking status on the plasma concentration of prolactin already elevated by risperidone treatment in schizophrenia patients

Keywords: 5-HT; 5-hydroxytryptamine; CNS; central nervous system; CV; coefficient of variation; CYP; cytochrome P450; DRD2; Dopamine D2 Receptor; GABA; gamma-aminobutyric acid; MDR1; Multidrug resistance 1; Gender; Prolactin; Risperidone; Smoking status;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Silencing activity of 2′-O-methyl modified anti-MDR1 siRNAs with mismatches in the central part of the duplexes

Keywords: RNA interference; siRNA; Thermodynamic stability; MDR1; 2′-O-Methyl modification;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

On-line identification of P-glycoprotein substrates by monitoring of extracellular acidification and respiration rates in living cells

Keywords: MDR1; multi-drug resistance gene 1 or ABCB1; P-gp; P-glycoprotein; ATP; adenosintriphosphate; ECAR; extracellular acidification rate; OCR; oxygen consumption rate; SEM; standard error of the mean; IDES; interdigitated electrode structure; ISFET; ion-sensi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Breed distribution of the nt230(del4) MDR1 mutation in dogs

Keywords: P-glycoprotein; MDR1; Dog; Ivermectin; Drug sensitivity

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Simultaneous detection of CYP3A5 and MDR1 polymorphisms based on the SNaPshot assay

Keywords: CYP3A5; MDR1; SNP; Genotyping; Sequencing

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Alkaloids derived from genus Veratrum and Peganum of Mongolian origin as multidrug resistance inhibitors of cancer cells

Keywords: Veratrum lobelianum; Veratrum nigrum; Peganum nigellastrum; Steroidal alkaloids; Multidrug resistance; MDR1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Correlation between genetic polymorphisms of the hOCT1 and MDR1 genes and the response to imatinib in patients newly diagnosed with chronic-phase chronic myeloid leukemia

Keywords: Chronic myeloid leukemia; Therapy; Imatinib; Genetic polymorphisms; hOCT1; MDR1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Acetaminophen-induced stimulation of MDR1 expression and activity in rat intestine and in LS 174T human intestinal cell line

Keywords: Acetaminophen; P-glycoprotein; MDR1; Intestine; LS 174T; Digoxin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of an antifungal peptide from Trapa natans fruits with inhibitory effects on Candida tropicalis biofilm formation

Keywords: AFP; antifungal peptides; Tn-AFP1; Trapa natans-antifungal peptide 1; HPLC; high performance liquid chromatography; LC-MS/MS; liquid chromatography tandem mass spectrometry; MALDI ToF MS; matrix assisted laser desorption ionization time of flight mass s

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Frequency of the C1236T, G2677T/A and C3435T MDR1 gene polymorphisms in the Serbian population

Keywords: MDR1; genetic polymorphism; P-glycoprotein; C1266T; G2677T/A; C3435T

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Alpha-tocopheryl succinate enhances doxorubicin-induced apoptosis in human gastric cancer cells via promotion of doxorubicin influx and suppression of doxorubicin efflux

Keywords: Alpha-tocopheryl succinate (α-TOS); Doxorubicin (DOXO); SGC-7901 gastric cancer cells; Apoptosis; MDR1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Polymorphisms of ERCC1 C118T/C8092A and MDR1 C3435T Predict Outcome of Platinum-based Chemotherapies in Advanced Non-small Cell Lung Cancer: A Meta-analysis

Keywords: Non-small cell lung; ERCC1; MDR1; Platinum; Chemotherapy; Meta-analysis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Predictive value of multidrug resistance proteins, topoisomerases II and ERCC1 in small cell lung cancer: A systematic review

Keywords: Small-cell lung cancer; Predictive factor; Multidrug resistance-associated proteins; MDR1; MRP; MVP; Topoisomerase II; ERCC1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Mitoxantrone is expelled by the ABCG2 multidrug transporter directly from the plasma membrane

Keywords: ABC transporter; ATP-binding cassette transporter; ABCG2; G2 multidrug transporter (breast cancer resistance protein, MXR/BCRP/ABCP); GFP; green fluorescent protein; GFP-G2; ABCG2 protein tagged with GFP; Ko143 or KO; specific inhibitor of ABCG2; MDR1; mu

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Sphingolipids and expression regulation of genes in cancer

Keywords: C1P; ceramide 1-phosphate; CAPP; ceramide-activated protein phosphatase; CerK; ceramide kinase; CerS; ceramide synthase; CERT; ceramide transfer protein; COX-2; cyclooxygenase-2; CPPase; ceramide phosphate phosphatase; CSC; cancer stem cell; ES; embryo st

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Extraction of tacit knowledge from large ADME data sets via pairwise analysis

Keywords: Pairwise; ADME; Activity cliff; Switch; HLM; Permeability; MDCK; P-gp; MDR1; Lipophilicity; Log D; SAR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Budesonide 9 mg Is at Least as Effective as Mesalamine 4.5 g in Patients With Mildly to Moderately Active Crohn's Disease

Keywords: Mesalamine; Mesalazine; RCT; Remission; CI; confidence interval; CRP; C-reactive protein; CYP; cytochrome P450; ITT; intent-to-treat; LOCF; last observation carried forward; MDR1; multidrug resistance 1 gene; OD; once daily; PP; per protocol;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

The role of P-glycoprotein and breast cancer resistance protein (BCRP) in bacterial attachment to human gastrointestinal cells

Keywords: Caco2; MDR1; E. coli; BCRP; IBD;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Retrovirus-mediated multidrug resistance gene (MDR1) overexpression inhibits chemotherapy-induced toxicity of granulosa cells

Keywords: Multi-drug resistance genes; MDR1; fertility preservation; premature ovarian failure; protection from chemotherapy toxicity;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Granulin-Epithelin Precursor and ATP-Dependent Binding Cassette (ABC)B5 Regulate Liver Cancer Cell Chemoresistance

Keywords: P-glycoprotein; Multiple Drug Resistance; MDR1; MRP1; ABC; adenosine triphosphate-dependent binding cassette; CI; confidence interval; GEP; granulin-epithelin precursor; HR; hazard ratio; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Expression of drug efflux transporters in poultry tissues

Keywords: Chicken; Efflux transporter; MDR1; MRP2

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Blood–brain barrier cell line PBMEC/C1-2 possesses functionally active P-glycoprotein

Keywords: Blood–brain barrier; PBMEC/C1-2; P-glycoprotein; ABCB1; MDR1; Antisense

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Drug resistant breast cancer cells overexpress ETS1 gene

Keywords: ETS1; MCF-7; MDR1; Matrix metalloproteinases; Microarray analysis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Modulation of human placental P-glycoprotein expression and activity by MDR1 gene polymorphisms

Keywords: Placenta; Membrane vesicle; p-Glycoprotein; MDR1; Polymorphism

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Association of MDR1 and ERCC1 polymorphisms with response and toxicity to cisplatin-based chemotherapy in non-small-cell lung cancer patients

Keywords: Single nucleotide polymorphism; Non-small cell lung cancer; Cisplatin; ERCC1; MDR1; Drug resistance

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Detection of the nt230[del4] MDR1 mutation in dogs by a fluorogenic 5′ nuclease TaqMan allelic discrimination method

Keywords: P-glycoprotein; MDR1; ABCB1; Allelic discrimination; Pharmacogenetics; Ivermectin sensitivity

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Up-regulation of renal Mdr1 and Mrp2 transporters during amiodarone pretreatment in rats

Keywords: Amiodarone; Mdr1; Mrp2; Cyp3a2; Mdr2; Rhodamine-123;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Garlic extract induces intestinal P-glycoprotein, but exhibits no effect on intestinal and hepatic CYP3A4 in humans

Keywords: Herbal medicines; Drug interactions; MDR1; P-glycoprotein; Pravastatin; Simvastatin; Saquinavir

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Bcr–Abl-independent mechanism of resistance to imatinib in K562 cells: Induction of cyclooxygenase-2 (COX-2) by histone deacetylases (HDACs)

Keywords: Imatinib-resistant K562 cells; MDR1; COX-2; HDACs; CREB; Bax; Bcl2

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Enhanced antitumor effects by combination gene therapy using MDR1 gene shRNA and HSV1-tk in a xenograft mouse model

Keywords: Combination gene therapy; HSV1-tk; shRNA; MDR1; 131I-FIAU imagingHSV1-tk, HSV1-thymidine kinase; MDR, multidrug resistance; shMDR, short hairpin RNA for the MDR1 gene; eGFP, enhanced green fluorescent protein; MTKG, stable cell line that expressed HSV1-tk

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

CpG hypomethylation of MDR1 gene in tumor and serum of invasive ductal breast carcinoma patients

Keywords: CpG Hypomethylation; MDR1; Breast cancer; Prognosis; Invasive ductal carcinoma

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه