Keywords: میانگین زمان اقامت; EPR; enhanced permeability and retention; FDA; food and drug administration; RES; reticuloendothelial system; NFP; nanofiber; 2D; 2-dimensional; 3D; 3-dimensional; ASTM; American Society for Testing and Materials; SCID; severe combined immunodeficiency; Q
مقالات ISI میانگین زمان اقامت (ترجمه نشده)
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Keywords: میانگین زمان اقامت; Mean residence time; Slurry utilization efficiency; Chemical mechanical planarization
Biochar vs. clay: Comparison of their effects on nutrient retention of a tropical Arenosol
Keywords: میانگین زمان اقامت; AEC; Anion exchange capacity; AR; Arenosol treatment (control); BC; Biochar treatment; CAL; Calcium-acetate-lactate; CEC; Cation exchange capacity; CL; Clay treatment; FDR; Frequency domain reflectometry; MRT; Mean residence time; RD; Relative difference;
Pharmacokinetics and toxicokinetics of d-serine in rats
Keywords: میانگین زمان اقامت; AUC; area under the plasma concentrationtime curve; AUC0-last; AUC from time 0 to the last point with a quantifiable plasma concentration; AUCip; AUC after intraperitoneal administration; bw; body weight; CLtot; total plasma clearance; Cmax; maximal plasm
Effects of Paullinia cupana extract on lamotrigine pharmacokinetics in rats: A herb-drug interaction on the gastrointestinal tract with potential clinical impact
Keywords: میانگین زمان اقامت; Herb-drug interaction; Lamotrigine; Paullinia cupana; Rats; AED; antiepileptic drug; AUC; area under the concentration-time curve; AUC0-24; AUC from time zero to 24â¯h; AUC0-t; AUC from time zero to the last measurable concentration; AUC0-â; AUC from t
N-acetylcysteine modified hyaluronic acid-paclitaxel conjugate for efficient oral chemotherapy through mucosal bioadhesion ability
Keywords: میانگین زمان اقامت; HA; hyaluronic acid; PTX; paclitaxel; NAC; N-acetylcysteine; DCC; dicyclohexylcarbodiimide; DMAP; 4-dimethylaminopyridine; DMF; N,N-dimethylformamide; NAC-HA-PTX; NAC modified HA-PTX; CMC; critical micelle concentration; C6; coumarin 6; DS; the degree of
In Vitro-In Vivo Evaluation of an Oral Ghost Drug Delivery Device for the Delivery of Salmon Calcitonin
Keywords: میانگین زمان اقامت; oral absorption; peptide delivery; pharamcokinetics; proteins; drug transport; polymer synthesis; OGDD; Oral Ghost Drug Delivery; UHMW-PE; ultra-high-molecular-weight polyethylene; AAm; polyethylene: acrylamide monomers; MAA; methyacrylic acid; BIS; N-N
Mass transfer of molybdenum in L35â¯+â¯sodium sulfateâ¯+â¯H2O aqueous two-phase system with a packed column
Keywords: میانگین زمان اقامت; Aqueous two-phase system; Packed column; Mean residence time; Mass transfer; Molybdenum;
Probabilistic distribution and stochastic P-bifurcation of a hybrid energy harvester under colored noise
Keywords: میانگین زمان اقامت; Stochastic P-bifurcation; Mean residence time; Stochastic resonance;
Identification of metabolites of MDR-1339, an inhibitor of β-amyloid protein aggregation, and kinetic characterization of the major metabolites in rats
Keywords: میانگین زمان اقامت; AD; alzheimer's disease; AUCINF; area under the concentration time curve from time zero to the last sampling time plus the extrapolated area (i.e., the last concentration divided by the elimination rate constant); AUClast; area under the concentration t
Novel cremochylomicrons for improved oral bioavailability of the antineoplastic phytomedicine berberine chloride: Optimization and pharmacokinetics
Keywords: میانگین زمان اقامت; BER; berberine chloride; CM; chylomicron; CrM; cremochylomicron; CHX; cycloheximide; P-gp; p-glycoprotein; PDI; polydispersity index; MRT; mean residence time; Berberine chloride (BER); Chylomicron (CM); Cremophor El; Lymphatic targeting; Cycloheximide (C
Ferrocene-based inhibitors of hepatitis C virus replication that target NS5A with low picomolar in vitro antiviral activity
Keywords: میانگین زمان اقامت; ABH; 2-azabicyclo[2.2.1]heptanyl; Bpin; (pinacolato)boryl; BZD; benzimidazolyl; CL; clearance; Cp; cyclopentadienyl; Fc; ferrocene or ferrocenyl; FcI2; 1,1â²-diiodoferrocene; FQ; ferroquine; GT; genotype; Im; imidazolyl; Moc; methoxycarbonyl; MRT; mean r
A systematic review of pharmacokinetic studies on herbal drug Fuzi: Implications for Fuzi as personalized medicine
Keywords: میانگین زمان اقامت; Aconitum carmichaeli Debx.; Aconitum alkaloids; Pharmacokinetics; Herb-drug interactions; Toxicology; Personalized medicine; DMEs; drug-metabolizing enzymes; ETs; efflux transporters; BB; bioavailability barrier; DDAs; diester-diterpene alkaloids; MDAs; m
Clinical benefits and pharmacology of scutellarin: A comprehensive review
Keywords: میانگین زمان اقامت; Aβ; β-amyloid peptide; ACE; angiotensin-converting enzyme; AD; Alzheimer's disease; ADE; adverse drug effect; ADR; adverse drug reaction; AIF; apoptosis-inducing factor; Akt; protein kinase B or PKB; ALS; amyotrophic lateral sclerosis; AMPK; AMP-activat
Botany, traditional use, phytochemistry, pharmacology, quality control, and authentication of Radix Gentianae Macrophyllae-A traditional medicine: A review
Keywords: میانگین زمان اقامت; Qinjiao; Phytochemical; Pharmacology; Pharmacokinetic; Quality control; Authentication; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AUC; area under curve; 6-BA; 6-benzylaminopurine; CCl4; carbon tetrachloride; Cl; clearance; Cmax; conc
Potent antiobesity effect of a short-length peptide YY-analogue continuously administered in mice
Keywords: میانگین زمان اقامت; Aib; 2-aminoisobutyric acid; BA; bioavailability; Cha; 3-cyclohexylalanine; CHO; Chinese hamster ovary; DIO; diet-induced obese; Hyp; trans-4-hydroxyproline; Leu(Me); γ-methylleucine; MAT; mean absorption time; MRT; mean residence time; RP-HPLC; reversed
Spatial controls of topsoil and subsoil organic carbon turnover under C3-C4 vegetation change
Keywords: میانگین زمان اقامت; Turnover time; Mean residence time; Delta 13C; Rock fragments; Particle-size organic matter; Maize biomass;
The pharmacokinetics and tissue distribution of coumaroylspinosin in rat: A novel flavone C-glycoside derived from Zizyphi Spinosi Semen
Keywords: میانگین زمان اقامت; AUC; area under the curve; CE; collision energy; CL; clearance rate; ESI; electrospray ionization; IS; internal standard; LLOQ; lower limit of quantification; MRM; multiple reaction monitoring; MRT; mean residence time; QC; quality control; RE; relative e
sec-Butylpropylacetamide (SPD), a new amide derivative of valproic acid for the treatment of neuropathic and inflammatory pain
Keywords: میانگین زمان اقامت; SPD; sec-butylpropylacetamide; VPA; valproic acid; CAPs; compound action potentials; AED; antiepileptic drugs; SNL; spinal nerve ligation; PK; pharmacokinetic; PD; pharmacodynamic; VFF; von-Frey filaments; MC; methyl cellulose; TPE; time to peak effect; A
Effect of gas rate and position of powder injection on RH refining process using numerical simulation
Keywords: میانگین زمان اقامت; RH-PB (powder blowing) process; Circulating flow rate; Mean residence time; Mathematical modeling; Refining effect;
Dual 7-ethyl-10-hydroxycamptothecin conjugated phospholipid prodrug assembled liposomes with in vitro anticancer effects
Keywords: میانگین زمان اقامت; SN38; 7-ethyl-10-hydroxycamptothecin; CPT-11; irinotecan; TEM; transmission electron microscopy; cyro-TEM; cryogenic transmission electron microscopy; FDA; Food and Drug Administration; DDS; drug delivery system; EPR; enhanced permeability and retention;
Discovery of Novel and Potent Stearoyl Coenzyme A Desaturase 1 (SCD1) Inhibitors as Anticancer Agents
Keywords: میانگین زمان اقامت; Ac; acetyl; ADME; absorption, distribution, metabolism, and excretion; aq.; aqueous; AUC; total area under the blood concentration-time curve; bid; bis in die (twice per day); Boc; (tert-butoxy)carbonyl; Bu; butyl; Bz; benzoyl; cLogP; calculate logarith
Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential
Keywords: میانگین زمان اقامت; ADME; absorption, distribution, metabolism, and excretion; AML; acute myelogenous leukemia; AUC; area under the blood concentration time curve; b.i.d.; twice a day; CDK; Cyclin-dependent kinase; CLtotal; clearance; Cmax; maximum drug concentration; CRC; c
Evaluation of Meropenem Penetration into Cerebrospinal Fluid in Patients with Meningitis After Neurosurgery
Keywords: میانگین زمان اقامت; Cerebrospinal fluid; Meropenem; Nosocomial infection; Penetration; Postneurosurgical meningitis; AUC; Area under the curve; CSF; Cerebrospinal fluid; MIC; Minimum inhibitory concentration; MRT; Mean residence time; PK; Pharmacokinetics;
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes
Keywords: میانگین زمان اقامت; AFE; Average Fold Error; AAFE; Absolute Average Fold Error; API; Active pharmaceutical ingredient; AUC; Area under the curve; BCS; Biopharmaceutics classification system; BE; Bioequivalence; BP; Blood-to-plasma ratio; CCC; Concordance Correlation Coeffici
Radiotracer investigations in pilot-scale soakers
Keywords: میانگین زمان اقامت; Visbreaking; Soaker; Radiotracer; Bromine-82; Dibromobiphenyl; Perforated baffles; Short residue; Vacuum gas oil; Residence time distribution; Mean residence time; Backmixing; Tanks-in-series with backmixing model
Synthesis, characterization and application of Au-198 nanoparticles as radiotracer for industrial applications
Keywords: میانگین زمان اقامت; Nanoparticles; Gold-198; Bromine-82; Radiotracer; Bubble column; Residence time distribution; Mean residence time; Tank-in-series with backmixing model;
Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitors
Keywords: میانگین زمان اقامت; AcOH; acetic acid; Ang I; angiotensin I; Ang II; angiotensin II; AUC; area under the blood concentration-time curve; C5min; concentration in plasma 5Â min after administration; CLtotal; total clearance; Cmax; maximum concentration in plasma; DIEA; N,N-d
NANEX: Process design and optimization
Keywords: میانگین زمان اقامت; One-step nano-extrusion process; NANEX design and optimization; Screw configuration; Water integration capacity; Mean residence time; Devolatilization;
Stable and radioactive carbon in forest soils of Chhattisgarh, Central India: Implications for tropical soil carbon dynamics and stable carbon isotope evolution
Keywords: میانگین زمان اقامت; Radiocarbon; Soil organic matter; Stable isotope; Mean residence time; Rayleigh fractionation
Reformulating cyclosporine A (CsA): More than just a life cycle management strategy
Keywords: میانگین زمان اقامت; ASC; adipose-derived stem cells; AUC; area under the curve; Capmul MCM; medium chain mono- and diglycerides; Compritol®888; glyceryl behenate; Cremophor® EL; ethoxylated castor oil; Cremophor® RH; polyoxyl 40 hydrogenated castor oil; CsA; cyclosporine
Stable loading and delivery of disulfiram with mPEG-PLGA/PCL mixed nanoparticles for tumor therapy
Keywords: میانگین زمان اقامت; DSF; disulfiram; mPEG-PLGA; methoxy poly(ethylene glycol)-b-poly(lactide-co-glycolide); PCL; poly(ε-caprolactone); NPs; nanoparticles; DMF; N,Nâ²-dimethylformamide; CH3CN; acetonitrile; DLS; dynamic light scattering; TEM; transmission electron microscop
Numerical investigation of bed depth height, axial velocity and mean residence time of inert particles in steady state industrial cement rotary kiln: Case of Figuil Plant in Cameroon
Keywords: میانگین زمان اقامت; Bed depth; Axial velocity; Mean residence time; Industrial cement rotary kiln
High-performance liquid chromatography-tandem mass spectrometry method for the determination of perampanel, a novel α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist in human plasma
Keywords: میانگین زمان اقامت; AED; anti-epileptic drugs; AMPA; α-amin-3-hydroxyl-5methyl-4isoxazolepropionic acid; AUC; area under the plasma concentration-time curve; AUC0-inf; AUC extrapolated to infinity; AUC0-last; AUC to the last time points; AUMC; area under the first mom
Optimization of a novel series of N-phenylindoline-5-sulfonamide-based acyl CoA:monoacylglycerol acyltransferase-2 inhibitors: Mitigation of CYP3A4 time-dependent inhibition and phototoxic liabilities
Keywords: میانگین زمان اقامت; ACAT; acyl CoA:cholesterol acyltransferase; ADME; absorption, distribution, metabolism and excretion; APCI; atomospheric pressure chemical ionization; CM; chylomicron; dba; dibenzylideneacetone; CYP; cytochrome P450; DDI; drug-drug interaction; DGAT; ac
Glycyrrhizin accelerates the metabolism of triptolide through induction of CYP3A in rats
Keywords: میانگین زمان اقامت; TWHF; Tripterygium wilfordii Hook F; TP; triptolide; GL; glycyrrhizin; KCZ; ketoconazole; MDZ; midazolam; OH-MDZ; 1׳-hydroxymidazolam; IS; internal standard; AUCâ; area under curve from dosing time extrapolated to infinity; MRTâ; mean residence time
Combination therapy with dendritic cell vaccine and IL-2 encapsulating polymeric micelles enhances intra-tumoral accumulation of antigen-specific CTLs
Keywords: میانگین زمان اقامت; PEG; Polyethylene glycol; AUC; Area under the concentration-time curve; MRT; Mean residence time; EPR effect; Enhanced permeability and retention effect; Immunotherapy; Dendritic cells; Interleukin-2; Drug delivery system; Cytotoxic T lymphocytes;
Pharmaceutical nanotechnologyOptimization of long circulating mixed polymeric micelles containing vinpocetine using simple lattice mixture design, in vitro and in vivo characterization
Keywords: میانگین زمان اقامت; Vinpocetine (PubChem CID: 443955); Pluronics (PubChem CID: 24751); Mannitol (PubChem CID: 6251); Sodium lauryl sulphate (PubChem CID: 3423265); Pluronic; Vinpocetine; Micelles; Lyophilization; Sterilization; Vivo; Mean residence time;
Enhanced oral bioavailability of capsaicin in mixed polymeric micelles: Preparation, in vitro and in vivo evaluation
Keywords: میانگین زمان اقامت; PVP; polyvinylpyrrolidone;; IVIVC; in vitro-in vivo correlation;; TEM; transmission electron microscopy;; EE; encapsulation efficiency;; CMCâNa; sodium carboxymethylcellulose;; MRT; mean residence time;; DLS; dynamic light scattering; Capsaicin; Micel
The influence of feedstock and production temperature on biochar carbon chemistry: A solid-state 13C NMR study
Keywords: میانگین زمان اقامت; Biochar; Solid-state 13C NMR spectroscopy; Aromatic condensation; Mean residence time; Carbon sequestration; Pyrolysis;
Asymmetric non-Gaussian effects in a tumor growth model with immunization
Keywords: میانگین زمان اقامت; Tumor growth with immunization; Stochastic dynamics of tumor growth; Asymmetric α-stable Lévy motion; Lévy jump measure; Mean residence time; Escape probability;
Biodistribution of Nanostructured Lipid Carriers (NLCs) after intravenous administration to rats: Influence of technological factors
Keywords: میانگین زمان اقامت; Size; Charge; Surfactant; Nanostructured lipid carriers; Biodistribution; High pressure homogenization; Mean residence time;
The anti-diabetic effects and pharmacokinetic profiles of berberine in mice treated with Jiao-Tai-Wan and its compatibility
Keywords: میانگین زمان اقامت; FBG; fasting blood glucose; OGTT; oral glucose tolerance test; BG; blood glucose; TC; total cholesterol; TG; triglyceride; LDL-c; low density lipoprotein; HDL-c; high density lipoprotein; Apo B; apolipoprotein B; STZ; streptozotocin; wt; weight; SD; stand
Hemolytic and pharmacokinetic studies of liposomal and particulate amphotericin B formulations
Keywords: میانگین زمان اقامت; AmB; Amphotericin B; RBCs; red blood cells; RES; reticulo-endothelial system; FD; non-microencapsulated free dimeric AmB formulation; F; Fungizone®; HF; heated-Fungizone; MD; microencapsulated dimer AmB; FP; non-microencapsulated free poly-aggregated AmB
Pharmacokinetics, brain distribution and plasma protein binding of carbamazepine and nine derivatives: New set of data for predictive in silico ADME models
Keywords: میانگین زمان اقامت; ADME; absorption distribution metabolism and excretion; AEDs; antiepileptic drugs; AUC; area under the plasma drug concentration-time curve; BBB; blood-brain barrier; CBZ; carbamazepine; CBZ-E; carbamazepine-10,11-epoxide; Cmax; maximum peak concentra
Pharmacokinetic study of salvianolic acid A in beagle dog after oral administration by a liquid chromatography-mass spectrometry method: A study on bioavailability and dose proportionality
Keywords: میانگین زمان اقامت; SAA; salvianolic acid A; IS; internal standard; CH3CN; acetonitrile; MeOH; methanol; HCOOH; formic acid; HCl; hydrochloric acid; EtOAc; ethyl acetate; VC; vitamin C; HPLC; high performance liquid chromatography; LC/MS/MS; liquid chromatography/tandem mass
A narrow residence time incubation reactor for continuous virus inactivation based on packed beds
Keywords: میانگین زمان اقامت; λ; wavelength; t; residence time; tx%; residence time at which the normalized signal reaches x %; tbatch; batch incubation time; tmean; mean residence time; tLOD; residence time at which the signal reaches the limit of detection; FLOD; cumulative RTD at
Inductive modulation on P-glycoprotein and cytochrome 3A by resveratrol, a constituent of grapes
Keywords: میانگین زمان اقامت; CsA; cyclosporine; P-gp; P-glycoprotein; CYP3A4; cytochrome P450 3A4; RDS; resveratrol dietary supplement; HPLC; high-performance liquid chromatography; Cmax; the peak blood concentration; AUC0-t; the areas under the curves from time zero to last; MRT;
Radiotracer investigation in gold leaching tanks
Keywords: میانگین زمان اقامت; Residence time distribution; Radioactive tracer; Mean residence time; Effective volume; Tanks-in-series model
Loading 3-deazaneplanocin A into pegylated unilamellar liposomes by forming transient phenylboronic acid-drug complex and its pharmacokinetic features in Sprague-Dawley rats
Keywords: میانگین زمان اقامت; ANOVA; one-way analysis of variance; AUC0-â; area under the concentration-time curve from time zero to infinity; BW; body weight; cis diol; vicinal hydroxyl groups; CL; clearance; Cmax; maximum plasma concentration; Cr; creatinine; DZNep; 3-deazanep