کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10435867 911017 2016 44 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Stable loading and delivery of disulfiram with mPEG-PLGA/PCL mixed nanoparticles for tumor therapy
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
پیش نمایش صفحه اول مقاله
Stable loading and delivery of disulfiram with mPEG-PLGA/PCL mixed nanoparticles for tumor therapy
چکیده انگلیسی
Disulfiram was loaded inside mPEG-PLGA/PCL mixed nanoparticles by nanoprecipitation, and the formed nanoparticles showed good disulfiram loading capacity and stability, and effectively protect disulfiram from degradation. In vivo studies proved that after entrapment, disulfiram was effective in in vivo tumor inhibition. Thus, the formula applied here made this un-applicable drug into applicable.70
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nanomedicine: Nanotechnology, Biology and Medicine - Volume 12, Issue 2, February 2016, Pages 377-386
نویسندگان
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