Keywords: شار متابولیک; aKG; α-ketoglutarate; AA; amino acid; BM; biomass; CCM; central carbon metabolism; CDW; cell dry weight; DNT; Developmental neurotoxicity; ECAR; extracellular acidification rate; ESI; Electrospray ionization; FCCP; Carbonyl cyanide-4-(trifluoromethoxy)ph
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Keywords: شار متابولیک; Central carbon metabolism; Specific rates; Metabolic flux; Gibbs free-energy change; Enzyme reaction kinetics;
Keywords: شار متابولیک; Long-chain base; Ceramide; Sphingolipids; Fluorescent sphingolipid; Stable isotope; Odd-chain tracer; Click-chemistry; Metabolic flux; Fungal sphingolipids; Mass spectrometry;
Keywords: شار متابولیک; 6PGDH; 6-phosphogluconate dehydrogenase; KATP; ATP-sensitive K+ channel; ER; endoplasmic reticulum; G6PDH; glucose-6-phosphate dehydrogenase; GC; gas chromatography; GHB; γ-hydroxybutyric acid; GSIS; glucose-stimulated insulin secretion; ICDc; cytosolic
Keywords: شار متابولیک; Biocatalyzed electrochemical system; Bioelectrochemical treatment; Microbial fuel cell; Microbial electrolysis cell; Metabolic flux;
Keywords: شار متابولیک; A. vinelandii; Metabolic flux; Alginate; Acetylation; PHB;
Keywords: شار متابولیک; Monoclonal antibody; Apoptosis; Metabolic flux; Modeling; Mammalian cell culture; Chinese hamster ovary; Model estimability;
Improved riboflavin production with Ashbya gossypii from vegetable oil based on 13C metabolic network analysis with combined labeling analysis by GC/MS, LC/MS, 1D, and 2D NMR
Keywords: شار متابولیک; Ashbya gossypii; Riboflavin; Vitamin B2; 13C tracer; Metabolic flux; Carbon-one metabolism; Glycine;
Monitoring in vivo metabolic flux with a designed whole-cell metabolite biosensor of shikimic acid
Keywords: شار متابولیک; Whole-cell biosensor; High-throughput screening; Metabolic flux; Regulatory protein; Shikimic acid;
Research articleRNAi-mediated suppression of dihydroflavonol 4-reductase in tobacco allows fine-tuning of flower color and flux through the flavonoid biosynthetic pathway
Keywords: شار متابولیک; Anthocyanin; DFR; FLS; Metabolic flux; Post transcriptional gene silencing; Proanthocyanidin; Tobacco;
Extraction, purification, methylation and GC-MS analysis of short-chain carboxylic acids for metabolic flux analysis
Keywords: شار متابولیک; Gas chromatography-mass spectrometry; Tricarboxylic acid cycle; Methylation; Carboxylic acid; Polar metabolites; Metabolic flux;
Introduction of the exogenous NADH coenzyme regeneration system and its influence on intracellular metabolic flux of Paenibacillus polymyxa
Keywords: شار متابولیک; Formate dehydrogenase; Metabolic flux; NADH regeneration; Paenibacillus polymyxa; R,R-2,3-butanediol;
TrpE feedback mutants reveal roadblocks and conduits toward increasing secondary metabolism in Aspergillus fumigatus
Keywords: شار متابولیک; Aspergillus fumigatus; Tryptophan metabolism; Secondary metabolism; Metabolic engineering; Metabolic flux; Fumiquinazoline;
Phenotyping hepatocellular metabolism using uniformly labeled carbon-13 molecular probes and LC-HRMS stable isotope tracing
Keywords: شار متابولیک; Metabolomics; Central carbon metabolism; Nitrogen metabolism; Cytoscape; High resolution mass spectrometry (HRMS); Metabolic Flux; HRMS; high resolution accurate mass spectrometry; F1P; fructose-1-phosphate; F6P; fructose-6-phosphate; G6P; glucose-6-phosp
Inhibition and in situ removal of organic acids during glucose/glycerol co-fermentation by Lactobacillus reuteri
Keywords: شار متابولیک; Product inhibition; Process integration; In situ removal; Lactic acid; Acetic acid; Metabolic flux
Flux control analysis of a lactate and sucrose metabolic network at different storage temperatures for Hami melon (Cucumis melo var. saccharinus)
Keywords: شار متابولیک; Hami melon (Cucumis melo var. saccharinus); Storage temperature; Metabolic flux; Metabolic control; Metabolic network; Metabolic enzyme expression;
Nitrate addition to groundwater impacted by ethanol-blended fuel accelerates ethanol removal and mitigates the associated metabolic flux dilution and inhibition of BTEX biodegradation
Keywords: شار متابولیک; Mixed substrates; BTEX; Fuel ethanol; Metabolic flux; Natural attenuation; GSIM
convISA: A simple, convoluted method for isotopomer spectral analysis of fatty acids and cholesterol
Keywords: شار متابولیک; Isotopomer spectral analysis; Metabolic flux; Fatty acid; Cholesterol;
Metabolic studies of temperature control strategy on poly(γ-glutamic acid) production in a thermophilic strain Bacillus subtilis GXA-28
Keywords: شار متابولیک; Poly(γ-glutamic acid); Bacillus sutilis; Temperature; Metabolic flux; Enzyme activity
Diverging pathways: Differential benzenoid and phenylpropanoid volatile production in Phlox subulata L. cultivars
Keywords: شار متابولیک; Phlox subulata; Polemoniaceae; GC-MS; Benzenoid; Phenylpropanoid; Metabolic flux;
Enhanced butanol production by modulation of electron flow in Clostridium acetobutylicum B3 immobilized by surface adsorption
Keywords: شار متابولیک; Butanol tolerance; Clostridium acetobutylicum; Immobilization; Metabolic flux; NAD(P)H;
Metabolic flux network analysis of fermentative hydrogen production: Using Clostridium tyrobutyricum as an example
Keywords: شار متابولیک; Glucose; Lactate/acetate; Metabolic flux; Hydrogen production; Hydraulic retention time
Metabolism and metabolic burden by α1-antitrypsin production in human AGE1.HN cells
Keywords: شار متابولیک; Mammalian cell; Cell culture; Biopharmaceutical; Metabolic flux; AAT deficiency; Therapeutic protein
Observation and identification of 2-C-methyl-d-erythritol-2,4-cyclopyrophosphate in horseweed and ryegrass treated with glyphosate
Keywords: شار متابولیک; MEP, methylerythritol 4-phosphate; MEcPP, 2-C-methyl-d-erythritol-2,4-cyclopyrophosphateGlyphosate; In vivo31P NMR; Metabolic flux; MEP pathway; Conyza canadensis; Lolium spp
Selective permeabilization for the high-throughput measurement of compartmented enzyme activities in mammalian cells
Keywords: شار متابولیک; Metabolism; Metabolic flux; Mammalian cell; Compartmentation; CHO; Kinetics
Metabolic manipulation of glycosylation disorders in humans and animal models
Keywords: شار متابولیک; Congenital Disorder of Glycosylation (CDG); Glycosylation; Mannose; Fucose; Developmental delay; Metabolic flux
Effects of amino acid transport limitations on cultured hepatocytes
Keywords: شار متابولیک; Cultured hepatocytes; Amino acid transport; Metabolic flux;
Metabolic flux and cell cycle analysis indicating new mechanism underlying process oscillation in continuous ethanol fermentation with Saccharomyces cerevisiae under VHG conditions
Keywords: شار متابولیک; Continuous ethanol fermentation; Saccharomyces cerevisiae; Very high gravity; Oscillation; Metabolic flux; Cell cycle
Energy metabolism during diapause in Culex pipiens mosquitoes
Keywords: شار متابولیک; Metabolic flux; Metabolic fate; Diapause; Energy metabolism; Gonotrophic cycle
Effects of continuous hypoxia on energy metabolism in cultured cerebro-cortical neurons
Keywords: شار متابولیک; HK; Hexokinase; PK; pyruvate kinase; LDH; lactate dehydrogenase; CS; citrate synthase; GHD; glutamate dehydrogenase; TCA cycle; tricarboxylic acid cycle; HIF; hypoxia-inducible factor; BCA; bicinchoninic acid; HRP; horse radish peroxidase; CO2; carbon dio
Distinct roles of two anaplerotic pathways in glutamate production induced by biotin limitation in Corynebacterium glutamicum
Keywords: شار متابولیک; Corynebacterium glutamicum; glutamate production; anaplerotic pathway; biotin; metabolic flux; nuclear magnetic resonance
Analysis of 13C labeling enrichment in microbial culture applying metabolic tracer experiments using gas chromatography–combustion–isotope ratio mass spectrometry
Keywords: شار متابولیک; 13C labeling; Tracer; GC–C–IRMS; Proteinogenic amino acid; Metabolic flux; Corynebacterium glutamicum
Global metabolic effects of glycerol kinase overexpression in rat hepatoma cells
Keywords: شار متابولیک; Glycerol kinase; Metabolic flux; Metabolic flux analysis; Pentose phosphate pathway; Isotopomer; Moonlighting enzyme; Moonlighting activity
MODEL FORMULATION FOR HYBRIDOMA CULTURES IN BATCH AND FED-BATCH MODE
Keywords: شار متابولیک; hybridoma; metabolic flux; quadratic programming; cross-correlation functions; parameter-estimation; Prediction
Incorporating metabolic flux ratios into constraint-based flux analysis by using artificial metabolites and converging ratio determinants
Keywords: شار متابولیک; Constraint-based flux analysis; Artificial metabolite; Converging ratio determinant (CRD); 13C-labeling experiment; Gas chromatography–mass spectrometry (GC–MS); Metabolic flux
Impact of hyperosmotic condition on cell physiology and metabolic flux distribution of Candida krusei
Keywords: شار متابولیک; Candida krusei; Enzyme activity; Glycerol; Hyperosmotic condition; Metabolic flux; Trehalose
Manipulation of the physiology of clavulanic acid biosynthesis with the aid of metabolic flux analysis
Keywords: شار متابولیک; Metabolic flux; Streptomyces; Clavulanic acid
Signal transduction and metabolic flux of β-thujaplicin and monoterpene biosynthesis in elicited Cupressus lusitanica cell cultures
Keywords: شار متابولیک; Biosynthetic enzyme; Cupressus lusitanica cell culture; Metabolic flux; Monoterpene profile; Signal transduction; β-thujaplicinAD, Actinomycin D; CH, cycloheximide; DMAPP, dimethylallyl pyrophosphate; DPI, diphenylene iodonium; EGTA, ethylene glycol-bis-β
15N-labeling to determine chlorophyll synthesis and degradation in Synechocystis sp. PCC 6803 strains lacking one or both photosystems
Keywords: شار متابولیک; MALDI-TOF MS; matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; OD730; optical density at 730 nm; PS; photosystem; SCP; small Cab-like protein; Chlorophyll turnover; Mass spectrometry; Metabolic flux; Photosystem I; Photosystem
The PEP-pyruvate-oxaloacetate node as the switch point for carbon flux distribution in bacteria
Keywords: شار متابولیک; C3-carboxylation; C4-decarboxylation; Anaplerosis; Gluconeogenesis; Metabolic flux; PEP-pyruvate-oxaloacetate node;