Keywords: گیرنده گلوتامات metabotropic 5; Aβ; amyloid Beta; AQP; aquaporin; AD; Alzheimer's disease; CNS; central nervous system; Cx; connexin; DS; Down syndrome; GJ; gap junction; GFAP; glial fibrillary acidic protein; GS; glutamine synthetase; HS; hippocampal sclerosis; IP3R2; inositol triph
مقالات ISI گیرنده گلوتامات metabotropic 5 (ترجمه نشده)
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Keywords: گیرنده گلوتامات metabotropic 5; Transcranial electrical stimulation; tDCS; tACS; tRNS; Neuromodulation; Animal models; AC; alternating current; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BDNF; brain-derived neurotrophic factor; DC; direct current; EEG; electroencephalo
Keywords: گیرنده گلوتامات metabotropic 5; Metabotropic glutamate receptor 5; Hepatoma; Parkinson's disease; Rotenone; Apoptosis;
Keywords: گیرنده گلوتامات metabotropic 5; AA; amino acid; Aβo; oligomeric β-amyloid; Aβ; β-amyloid; AD; Alzheimer's disease; α7nAChR; α7 nicotinic acetylcholine receptor; ALS; amyotrophic lateral sclerosis; APLP1; amyloid beta precursor-like protein 1; APP; amyloid precursor protein; β-A
Keywords: گیرنده گلوتامات metabotropic 5; P2Â ÃÂ 7; purinergic receptor P2Â ÃÂ 7; mGluR5; metabotropic glutamate receptor 5; DAT; dopamine transporter; AQP4; aquaporin-4; DOPE; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; GLT-1; glutamate transporter-1; Cav1.2; L-type voltage-gated calcium ch
Keywords: گیرنده گلوتامات metabotropic 5; Biased agonism; Positive allosteric modulator; Stimulus bias; Metabotropic glutamate receptor 5; Glutamate (L-glutamic acid PubChem CID: 33032); DHPG (PubChem CID: 108001); VU0424465 (PubChem CID: 53384864); VU0403602 (PubChem CID: 53384878); VU29 (PubChe
Keywords: گیرنده گلوتامات metabotropic 5; DMAC; N,N-dimethylacetamide; DMF; N,N-dimethylformamide; LiHMDS; lithium bis(trimethylsilyl)amide; mGlu5; metabotropic glutamate receptor subtype 5; NAM; negative allosteric modulator; GPCR; G-protein coupled receptor; TFA; trifluoroacetic acid; TLC; thin
Keywords: گیرنده گلوتامات metabotropic 5; mGluR5; mGlu5; Metabotropic glutamate receptor 5; Schizophrenia; NMDA receptor; Positive allosteric modulator; PAM; Antipsychotic;
Neurogranin in the nucleus accumbens regulates NMDA receptor tolerance and motivation for ethanol seeking
Keywords: گیرنده گلوتامات metabotropic 5; Ethanol; Neurogranin; Operant conditioning; Glutamate receptors; Nucleus accumbens; Motivation; NMDAR; of N-methyl-d-aspartate receptors; Ng; Neurogranin; AUD; alcohol use disorders; mGluR5; metabotropic glutamate receptor 5; NAc; nucleus accumbens; AAV;
PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease
Keywords: گیرنده گلوتامات metabotropic 5; Alzheimer's disease; Mouse model; Non-receptor tyrosine protein kinase; Pyk2; Src; 5XFAD; mice transgenic for human APP and presenilin1 with 5 mutations found in familial Alzheimer's disease; AAV; adeno-associated virus; Aβ; amyloid β; AD; Alzheimer's d
Impact of Thalamocortical Input on Barrel Cortex Development
Keywords: گیرنده گلوتامات metabotropic 5; AC1; adenylyl cyclase 1; CTAs; corticothalamic axons; ION; infraorbital nerve injury; mGluR5; metabotropic glutamate receptor 5; PSPB; pallial-subpallial boundary; RIM; Rab3 interacting molecules; TCAs; thalamocortical axons; VPM; ventro-posteromedial nuc
Endocannabinoid Signaling in Embryonic Neuronal Motility and Cell-Cell Contact - Role of mGluR5 and TRPC3 Channels
Keywords: گیرنده گلوتامات metabotropic 5; 2-AG; 2-arachidonoyl glycerol; [Ca2+]i; intracellular free calcium concentration; Afatinib; N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; AM251; 1-(2,4-dichlorophenyl)-5-(4-iodophe
The metabotropic glutamate receptor 5 radioligand [11C]AZD9272 identifies unique binding sites in primate brain
Keywords: گیرنده گلوتامات metabotropic 5; PET imaging; Autoradiography; Metabotropic glutamate receptor 5; Negative allosteric modulator; AZD9272; Fenobam;
Rescue of Fmr1KO phenotypes with mGluR5 inhibitors: MRZ-8456 versus AFQ-056
Keywords: گیرنده گلوتامات metabotropic 5; mGluR5; Fmr1; MRZ-8456; AFQ-056; MPEP; Amyloid-beta precursor protein; Aβ; amyloid-beta; ABC-C; Aberrant Behavior Checklist-Community Edition; AGS; audiogenic-induced seizures; APP; amyloid-beta protein precursor; CNS; central nervous system; CTEP; 2-chl
Triptolide up-regulates metabotropic glutamate receptor 5 to inhibit microglia activation in the lipopolysaccharide-induced model of Parkinson's disease
Keywords: گیرنده گلوتامات metabotropic 5; mGlu; Metabotropic glutamate receptor; PD; Parkinson's disease; T10; Triptolide; LPS; lipopolysaccharide; NO; nitric oxide; iNOS; inducible nitric oxide synthase; TNF; tumor necrosis factor; IL; interleukin; SN; substantia nigra; COX; cyclooxygenase; JN
Environmental enrichment enhances cognitive flexibility in C57BL/6 mice on a touchscreen reversal learning task
Keywords: گیرنده گلوتامات metabotropic 5; Cognitive stimulation; Physical activity; Cognition; Brain reserve; Metabotropic glutamate receptor 5; Cognitive enhancers;
Metabotropic glutamate receptor 5 mediates the suppressive effect of 6-OHDA-induced model of Parkinson's disease on liver cancer
Keywords: گیرنده گلوتامات metabotropic 5; PD; Parkinson's disease; 6-OHDA; 6-hydroxydopamine; mGluR5; metabotropic glutamate receptor 5; TH; tyrosine hydroxylase; MPEP; 2-methyl-6-(phenylethyl)-pyridine; DHPG; (S)-3,5-dihydroxyphenylglycine; CREB; cAMP-response element binding protein; ERK; ext
Shifting towards a model of mGluR5 dysregulation in schizophrenia: Consequences for future schizophrenia treatment
Keywords: گیرنده گلوتامات metabotropic 5; Metabotropic glutamate receptor 5; mGluR5; Protein regulation; Glutamate; Schizophrenia; Novel therapy; 7TMD; 7-transmembrane domain; BA; Brodmann Area; BDNF; brain-derived neurotrophic factor; CA; Cornu ammonis; Ca2+; Calcium ions; Calcineurin/PPB2; prot
Targeting glutamatergic and cellular prion protein mechanisms of amyloid β-mediated persistent synaptic plasticity disruption: Longitudinal studies
Keywords: گیرنده گلوتامات metabotropic 5; Alzheimer's disease; Long-term potentiation; Glutamate-oxalate transaminase; Metabotropic glutamate receptor 5; APP transgenic rat;
Acute inhibition of mGluR5 disrupts behavioral flexibility
Keywords: گیرنده گلوتامات metabotropic 5; mGluR5; metabotropic glutamate receptor 5; MPEP; [2-Methyl-6-(phenylethynyl) pyridine hydrochloride]; PTSD; post-traumatic stress disorder; Extinction; Contextual fear memory; Spatial memory; mGluR5; MPEP; PTSD;
A systems pharmacology approach to decipher the mechanism of danggui-shaoyao-san decoction for the treatment of neurodegenerative diseases
Keywords: گیرنده گلوتامات metabotropic 5; DSS; danggui-shaoyao-san; NDs; neurodegenerative diseases; TCM; traditional Chinese medicine; AD; Alzheimer's disease; PD; Parkinson's disease; HD; Huntington's disease; ALS; amyotrophic lateral sclerosis; AIA; aspirin-intolerant asthma; PRA; Paeoniae Rad
Astrocytes in physiological aging and Alzheimer's disease
Keywords: گیرنده گلوتامات metabotropic 5; 3xTg-AD; triple transgenic mice model of Alzheimer's disease; AD; Alzheimer's disease; APP; amyloid precursor protein; ATP; adenosine triphosphate; CA1; Cornu Ammonis 1; CNS; Central nervous system; DG; dentate gyrus; GABA; γ-aminobutyric acid; GFAP;
Blockade of metabotropic glutamate receptor 5 protects against DNA damage in a rotenone-induced Parkinson's disease model
Keywords: گیرنده گلوتامات metabotropic 5; DHPG; (s)-3,5- dihydroxy-phenylglycine; DMSO; dimethylsulfoxide; ERK; extracellular signal-regulated kinase; MAPK; mitogen-activated protein kinase; mGluR5; metabotropic glutamate receptor 5; MPEP; 2-methyl-6-(phenylethynyl)pyridine; PD; Parkinson's dis
Age-dependent suppression of hippocampal epileptic afterdischarges by metabotropic glutamate receptor 5 antagonist MTEP
Keywords: گیرنده گلوتامات metabotropic 5; Epileptic afterdischarge; Hippocampus; Rat; Ontogeny; Metabotropic glutamate receptor 5
Spinal administration of mGluR5 antagonist prevents the onset of bortezomib induced neuropathic pain in rat
Keywords: گیرنده گلوتامات metabotropic 5; Bortezomib; Neuropathy; Metabotropic glutamate receptor; glutamate reuptake; Hyperalgesia; BINP; Bortezomib induced neuropathy; MPEP; Methyl-6-(phenylethynyl)-pyridine; mGluR5; Metabotropic glutamate receptor 5; SNCV; sensory nerve conduction velocity;
Microinjection of the mGluR5 antagonist MTEP into the nucleus accumbens attenuates the acquisition but not expression of morphine-induced conditioned place preference in rats
Keywords: گیرنده گلوتامات metabotropic 5; Metabotropic glutamate receptor 5; Nucleus accumbens; Acquisition; Expression; Morphine; Conditioned place preference; Rat
Imaging Glutamate Homeostasis in Cocaine Addiction with the Metabotropic Glutamate Receptor 5 Positron Emission Tomography Radiotracer [11C]ABP688 and Magnetic Resonance Spectroscopy
Keywords: گیرنده گلوتامات metabotropic 5; Addiction; cocaine; cocaine self-administration; magnetic resonance spectroscopy; metabotropic glutamate receptor 5; positron emission tomography;
Intrathecal administration of roscovitine prevents remifentanil-induced postoperative hyperalgesia and decreases the phosphorylation of N-methyl-d-aspartate receptor and metabotropic glutamate receptor 5 in spinal cord
Keywords: گیرنده گلوتامات metabotropic 5; Opioid-induced hyperalgesia; Remifentanil; Cyclin-dependent kinase 5; N-methyl-d-aspartate receptor; Metabotropic glutamate receptor 5
Haloperidol-induced Nur77 expression in striatopallidal neurons is under the control of protein phosphatase 1 regulation by DARPP-32
Keywords: گیرنده گلوتامات metabotropic 5; Striatum; Dopamine; Orphan nuclear receptors; Antipsychotics; A2AR; adenosine 2A receptor; CDK5; cyclin-dependent kinase 5; DAPI; 4â²,6â²-Diamidino-2-phenylindole; DARPP-32; dopamine- and cAMP-regulated phosphoprotein of 32Â kDa; D1R, D2R, and D3R; dopa
Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis
Keywords: گیرنده گلوتامات metabotropic 5; ALS; amyotrophic lateral sclerosis; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; [3H]d-Asp; [3H]d-aspartate; CAT; catalase; 3,5-DHPG; (S)-3,5-dihydroxyphenylglycine; Gapdh; Glyceraldehyde 3-phosphate dehydrogenase; Glu; glutamate; LTR; long t
Activation of metabotropic glutamate receptor 5 reduces the secondary brain injury after traumatic brain injury in rats
Keywords: گیرنده گلوتامات metabotropic 5; Traumatic brain injury; Metabotropic glutamate receptor 5; Inflammation;
Modulating mGluR5 and 5-HT1A/1B receptors to treat l-DOPA-induced dyskinesia: Effects of combined treatment and possible mechanisms of action
Keywords: گیرنده گلوتامات metabotropic 5; l-DOPA-induced dyskinesia; Parkinson's disease; Metabotropic glutamate receptor 5; DA agonist; 6-OHDA rat model; 5-HT1A/1B agonists;
Effects of a metabotropic glutamate receptor 5 positive allosteric modulator, CDPPB, on spatial learning task performance in rodents
Keywords: گیرنده گلوتامات metabotropic 5; Barnes maze; T-maze; Spatial learning; CDPPB; Metabotropic glutamate receptor 5
mGluR5 stimulating Homer–PIKE formation initiates icariin induced cardiomyogenesis of mouse embryonic stem cells by activating reactive oxygen species
Keywords: گیرنده گلوتامات metabotropic 5; Embryonic stem cells; Cardiomyocytes; Icariin; Metabotropic glutamate receptor 5; Homer–PIKE complex; Reactive oxygen species
Repeated potentiation of the metabotropic glutamate receptor 5 and the alpha 7 nicotinic acetylcholine receptor modulates behavioural and GABAergic deficits induced by early postnatal phencyclidine (PCP) treatment
Keywords: گیرنده گلوتامات metabotropic 5; Phencyclidine; Prefrontal cortex; GABAergic inhibitory function; Prepulse inhibition; Metabotropic glutamate receptor 5; Alpha 7 nicotinic acetylcholine receptorACSF, artificial cerebrospinal fluid; α7 nAChRs, α7 nicotinic acetylcholine receptors; ASR, ac
Optimization of an ether series of mGlu5 positive allosteric modulators: Molecular determinants of MPEP-site interaction crossover
Keywords: گیرنده گلوتامات metabotropic 5; Metabotropic glutamate receptor 5; mGlu5; Positive allosteric modulator (PAM); Non-MPEP
Expression and cell distribution of metabotropic glutamate receptor 5 in the rat cortex following traumatic brain injury
Keywords: گیرنده گلوتامات metabotropic 5; Traumatic brain injury; Metabotropic glutamate receptor 5; Rat cortex; Expression; Fluoro-Jade C;
Extracellular cysteine (Cys)/cystine (CySS) redox regulates metabotropic glutamate receptor 5 activity
Keywords: گیرنده گلوتامات metabotropic 5; Extracellular cysteine (Cys)/cystine (CySS); Metabotropic glutamate receptor 5; Parkinson's disease; AMS; 4-Acetamide-4â²-maleimidylstilbene-2,2â²-disulfonic acid, disodium salt; BCA; Bradford Protein Assay; CRD; cysteine-rich domain; Cys; cysteine; C
Discovery of novel positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)
Keywords: گیرنده گلوتامات metabotropic 5; mGlu5; Metabotropic glutamate receptor 5; Glutamate; NMDAr; N-Methyl-d-aspartate receptor; Positive allosteric modulator; Schizophrenia
Functional interaction of mGlu5 and NMDA receptors in aversive learning in rats
Keywords: گیرنده گلوتامات metabotropic 5; Inhibitory avoidance; Conditioned taste aversion; Open-field; Metabotropic glutamate receptor 5; NMDA receptor
Preclinical profile of a novel metabotropic glutamate receptor 5 positive allosteric modulator
Keywords: گیرنده گلوتامات metabotropic 5; Metabotropic glutamate receptor 5; mGlu5; Allosteric modulator; Schizophrenia
A prolonged pharmacological blockade of type-5 metabotropic glutamate receptors protects cultured spinal cord motor neurons against excitotoxic death
Keywords: گیرنده گلوتامات metabotropic 5; Amyotrophic lateral sclerosis; Motor neuron; Astrocyte; Excitotoxicity; Metabotropic glutamate receptor 5; MPEP; BDNF;
Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator
Keywords: گیرنده گلوتامات metabotropic 5; NMDA(N-methyl-D-aspartate)-receptor; mGlu5 receptor; Metabotropic glutamate receptor 5; Positive allosteric modulator; ADX-47273; Long-term potentiation
Group 5 metabotropic glutamate receptors: Role in modulating cortical activity and relevance to cognition
Keywords: گیرنده گلوتامات metabotropic 5; Metabotropic glutamate receptor 5; NMDA glutamate receptor; Schizophrenia; Prefrontal cortex; Cognitive enhancer
Metabotropic Glutamate Receptor 5/Homer Interactions Underlie Stress Effects on Fear
Keywords: گیرنده گلوتامات metabotropic 5; Conditioned fear; constitutive activity; Homer; metabotropic glutamate receptor 5; posttraumatic stress disorder; stress
Metabotropic glutamate receptor subtype 5 antagonism in learning and memory
Keywords: گیرنده گلوتامات metabotropic 5; Metabotropic glutamate receptor 5; Spatial learning; Fear conditioning; Avoidance learning; MPEP; MTEP; Locomotion; (Rat); (Mouse)
Discovery and SAR of 6-substituted-4-anilinoquinazolines as non-competitive antagonists of mGlu5
Keywords: گیرنده گلوتامات metabotropic 5; Glutamate; Metabotropic glutamate receptor 5; Negative allosteric modulator; Non-competitive antagonist; Quinazoline
Metabotropic glutamate receptor 5 in conditioned taste aversion learning
Keywords: گیرنده گلوتامات metabotropic 5; Metabotropic glutamate receptor 5; Conditioned taste aversion; Amygdala; Insular cortex; Acquisition
The role of metabotropic glutamate receptor 5 in developmental lead neurotoxicity
Keywords: گیرنده گلوتامات metabotropic 5; Lead; Developmental neurotoxicity; Metabotropic glutamate receptor 5; Hippocampus; Rat;
Dopamine D1 receptor-dependent modifications in the dopamine and cAMP-regulated phosphoprotein of Mr 32 kDa phosphorylation pattern in striatal areas of morphine-sensitized rats
Keywords: گیرنده گلوتامات metabotropic 5; caudate putamen; nucleus accumbens; metabotropic glutamate receptor 5; MGluR5; μ-opioid receptor; unavoidable stressANOVA, analysis of variance; CPu, caudate-putamen; DARPP-32, dopamine and cAMP-regulated phosphoprotein of Mr 32 kDa; mGluR5, metabotropic