Keywords: Hippocampus; MG132; Proteasome; Spatial memory; Sulforaphane; Synaptic Plasticity;
مقالات ISI (ترجمه نشده)
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Keywords: ALIX; apoptosis-linked gene-2-interacting protein X; BAG3; BCL2-associated athanogene 3; BAP; 5-(biotinamido)pentylamine; ESCRT; endosomal sorting complex required for transport; HEK293; human embryonic kidney cells; MEF; murine embryonic fibroblasts; mHt
Keywords: Metabolic crisis; tPA; p38; PI3K; Translation; MG132;
Infectious bursal disease virus protein VP4 suppresses type I interferon expression via inhibiting K48-linked ubiquitylation of glucocorticoid-induced leucine zipper (GILZ)
Keywords: GILZ; glucocorticoid-induced leucine zipper; CHX; cycloheximide; MG132; Z-Leu-Leu-Leu-al; Ub; ubiquitylation; IBDV; , infectious bursal disease virus; IBDV VP4; GILZ; Ubiquitylation; Post-translational modification; Immunosuppression; Type I interferon;
Facilitation of 9,10-phenanthrenequinone-elicited neuroblastoma cell apoptosis by NAD(P)H:quinone oxidoreductase 1
Keywords: 9,10-Phenanthrenequinone; Neuroblastoma cell; Apoptosis; Reactive oxygen species; Antioxidant property; NAD(P)H:quinone oxidoreductase 1; AKR; aldo-keto reductase; AMC; 7-amido-4-methylcoumarin; ATM; ataxia telangiectasia mutated kinase; BSO; dl-buthionin
Effect of isothiocyanates, BITC and PEITC, on stress protein accumulation, protein aggregation and aggresome-like structure formation in Xenopus A6 kidney epithelial cells
Keywords: Amphibian; Frog; Heme oxygenase-1; Isothiocyanates; Protein aggregates; Aggresomes; Heat shock protein; MG132;
Posttranslational regulation of CYP2J2 by nitric oxide
Keywords: 3-MA; 3-methyladenine; AA; arachidonic acid; ASC; ascorbate; Bort; bortezomib; BST; biotin-switch technique; Calp; calpeptin; CHX; cycloheximide; Dan; danazol; DMEM; Dulbecco's modified Eagle Medium; DPTA; dipropylenetriamine NONOate; EETs; epoxyeicosatri
Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome
Keywords: AMP-activated protein kinase (AMPK); Hutchinson-Gilford progeria syndrome (HGPS); Oocyte; HIV-1 latency; Rapamycin; Metformin; Retinoic acid; Methylene blue; Sulforaphane; Oltipraz; Vitamin D; MG132; Acrosome; Alternative splicing; ULK1; Autophagy; PGC-1Î
Nitric oxide-regulated proteolysis of human CYP2B6 via the ubiquitin-proteasome system
Keywords: AAF; L-alanyl-N-[(1S)â3-chloro-2-oxo-1-(phenylmethyl)propyl]-L-alaninamide, mono trifluoro-acetate; ALLN; N-acetyl-L-leucyl-N-[(1S)â1-formylpentyl]-L-leucinamide; Cal III; N-[(1S)â1-[[(1-formyl-2-phenylethyl)amino]carbonyl]â2-methylpropyl]-carbami
α-Pyrrolidinononanophenone provokes apoptosis of neuronal cells through alterations in antioxidant properties
Keywords: AMC; 7-amido-4-methylcoumarin; AMPK; AMP kinase; BSO; DL-buthionine-(S,R)-sulfoximine; DCFH-DA; 6-carboxy-2â²,7â²-dichloro-dihydrofluorescein diacetate-di(acetoxymethylester); DEM; diethylmaleate; DMF; N,N-dimethylformamide; DPBS; Dulbecco's phosphate
Effects of MG132 on the in vitro development and epigenetic modification of Debao porcine somatic cell nuclear transfer embryos
Keywords: MG132; Somatic cell nuclear transfer; Debao black porcine; Zygotic genome activation; Epigenetic modification;
Proteasome Inhibitor-Loaded Micelles Enhance Antitumor Activity Through Macrophage Reprogramming by NF-κB Inhibition
Keywords: macrophage reprogramming; NF-κB; proteasome inhibitor; polymeric micelles; MG132; breast cancer;
Postnatal Proteasome Inhibition Promotes Amyloid-β Aggregation in Hippocampus and Impairs Spatial Learning in Adult Mice
Keywords: APP-CTFβ; amyloid precursor protein C-terminal fragments; EDTA; ethylenediaminetetraacetic acid; EGTA; (ethylene glycol-bis(β-aminoethyl ether)-N,N,Nâ²,Nâ²-tetraacetic acid; LTP; long-term potentiation; MVBs; multivesicular bodies; MWM; Morris water m
Methylglyoxal-induced AMPK activation leads to autophagic degradation of thioredoxin 1 and glyoxalase 2 in HT22 nerve cells
Keywords: ACC; acetyl co-enzyme A carboxylase; AGE; advanced glycation end products; AMPK; 5â² AMP-activated protein kinase; ATG; autophagy related; BAF; bafilomycin; CQ; chloroquine; DMEM; high-glucose Dulbecco's modified Eagle medium; Glo; glyoxalase; GSH; gluta
The molecular mechanisms of XBP-1 gene silencing on IRE1α-TRAF2-ASK1-JNK pathways in oral squamous cell carcinoma under endoplasmic reticulum stress
Keywords: MG132; Oral squamous cell carcinoma; X-box binding protein 1; Apoptosis; Silencing
CED-4 is an mRNA-binding protein that delivers ced-3 mRNA to ribosomes
Keywords: Apoptosis; RNA binding protein; L10a; Translation; Translocation; ced; cell death abnormal; egl; egg-laying defective; HEK; human embryonic kidney; GFP; green fluorescent protein; MG132; Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal, Z-LLL-CHO;
Proteasome inhibitor MG132 impairs autophagic flux through compromising formation of autophagosomes in Bombyx cells
Keywords: Insect; Silkworm; Bombyx mori; Autophagy; Atg8; MG132;
The effect of peptidic and non-peptidic proteasome inhibitors on the biological properties of Acanthamoeba castellanii belonging to the T4 genotype
Keywords: Protozoa; Acanthamoeba; Encystation; Bortezomib; MG132; Lactacystin
Expression and localization of the Xenopus laevis small heat shock protein, HSPB6 (HSP20), in A6 kidney epithelial cells
Keywords: Amphibian; Frog; Molecular chaperone; Immunocytochemistry; Immunoblots; Protein aggregates; MG132; Cadmium
Proteasomal inhibition potentiates drugs targeting DNA topoisomerase II
Keywords: DNA topoisomerase II; Proteasome; Mitoxantrone; Velcade; MG132;
Cannabinoid receptor 2 expression modulates Gβ1γ2 protein interaction with the activator of G protein signalling 2/dynein light chain protein Tctex-1
Keywords: 2-AG (PubChem CID: 5282280); AM 630 (PubChem CID: 4302963); Ammonium chloride (PubChem CID: 25517); Bafilomycin A1 (PubChem CID: 25517); Cycloheximide (PubChem CID: 6197); JWH 133 (PubChem CID: 6918505); Leupeptin hemisulfate (PubChem CID: 2733491); MG132
Revealing the fate of cell surface human P-glycoprotein (ABCB1): The lysosomal degradation pathway
Keywords: ABC; ATP-binding cassette; P-gp; P-glycoprotein; FITC; fluorescein isothiocianate; BafA1; bafilomycin A1; MG132; carbobenzoxy-l-leucyl-l-leucyl-l-leucinal; MG115; carbobenzoxy-l-leucyl-l-leucyl-l-norvalinal; PSI; proteasome inhibitor I; Rh123; rhodamine12
Aberrant C-terminal domain of polymerase η targets the functional enzyme to the proteosomal degradation pathway
Keywords: Translesion synthesis; XP-V; Xeroderma pigmentosum variant; Bortezomib; MG132; Ubiquitin/proteasome system; Ultraviolet;
Nuclear factor-kappa B regulates pain and COMT expression in a rodent model of inflammation
Keywords: Complete Freund's adjuvant (CFA); MG132; Astrocytes; Catecholamines; Tumor necrosis factor-α (TNFα);
Investigation of lactate calcium salt-induced β-catenin destabilization in colorectal cancer cells
Keywords: CaLa; lactate calcium salt; CRC; colorectal cancer; GSK; glycogen synthase kinase; APC; adenomatous polyposis coli; CBP; CREB binding protein; TCF; T-cell factor; PBS; phosphate-buffered saline; MG132; carbobenzoxy-Leu-Leu-leucinal; pGSK; phosphorylated G
Carbon monoxide released by CORM-401 uncouples mitochondrial respiration and inhibits glycolysis in endothelial cells: A role for mitoBKCa channels
Keywords: CO; carbon monoxide; CO-RMs; CO-releasing molecules; CORM-401; Mn(CO)4{S2CNMe(CH2CO2H)}; iCORM-401; inactive CORM-401; BKCa; large-conductance calcium-regulated potassium ion channels; mitoBKCa; mitochondrial large-conductance calcium-regulated potassium
Valproic acid downregulates Cdk5 activity via the transcription of the p35 mRNA
Keywords: Cdk5; cyclin-dependent kinase 5; GABA; γ-aminobutyric acid; HDAC; histone deacetylase; MG132; benzyloxycarnonyl-leucyl-leucyl-leucinal; TSA; trichostatin A; VPA; valproic acid; VPM; valpromide; Cdk5; Valproic acid; Transcription; p35; Autism; HDAC;
The ubiquitin-proteasome system is required for the early stages of porcine circovirus type 2 replication
Keywords: PCV2; UPS; MG132; Lactacystin; Viral replication; PK15 cells;
Role of the ubiquitin-proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice
Keywords: ATF6; activating transcription factor 6; ATGL; adipose triglyceride lipase; AKO; adipose triglyceride lipase knockout; AMC; amino-4-methylcoumarin; CHOP; C/EBP homologous protein; EDTA; ethylenediaminetetraacetic acid; ER; endoplasmic reticulum; FA; fatty
Selective intracellular delivery of proteasome inhibitors through pH-sensitive polymeric micelles directed to efficient antitumor therapy
Keywords: Proteasome inhibitor; MG132; Polymeric micelle; pH-sensitive; Antitumor efficacy;
Synergism of arsenic trioxide and MG132 in Raji cells attained by targeting BNIP3, autophagy, and mitochondria with low doses of valproic acid and vincristine
Keywords: Synergism; BNIP3; Mitochondria; Mitophagy; Autophagy; Targeted combined therapies; Arsenic trioxide; MG132; Valproic acid; Burkitt's lymphoma;
Proteasome inhibitor MG132 induces NAG-1/GDF15 expression through the p38 MAPK pathway in glioblastoma cells
Keywords: NAG-1; nonsteroidal anti-inflammatory drug-activated gene-1; GDF-15; growth differentiation factor-15; GBM; glioblastoma multiforme; NAG-1/GDF15; MG132; Glioblastoma; P38 MAPK;
Proteasome inhibitor MG132 enhances TRAIL-induced apoptosis and inhibits invasion of human osteosarcoma OS732 cells
Keywords: Osteosarcoma; MG132; TRAIL; Apoptosis; Invasion;
Ileal apical sodium-dependent bile acid transporter protein levels are down-regulated through ubiquitin-dependent protein degradation induced by bile acids
Keywords: ASBT; Ubiquitination; Bile acid; Enterobacteria; Antibiotics; MG132;
Involvement of the proteasome and caspase activation in hippocampal long-term depression induced by the serine protease subtilisin
Keywords: aCSF; artificial cerebrospinal fluid; CED; Cambridge Electronic Design; DHPG; dihydroxyphenylglycine; fEPSPs; field excitatory synaptic potentials; HRP; horseradish peroxidase; LTD; long-term depression; LTP; long-term potentiation; MG132; N-[(phenylmetho
Proteasome inhibitors protect the steatotic and non-steatotic liver graft against cold ischemia reperfusion injury
Keywords: Ischemia reperfusion injury; Steatotic liver; UW preservation solution; Bortezomib; MG132; UPS inhibitor
Dexamethasone accelerates degradation of aryl hydrocarbon receptor (AHR) and suppresses CYP1A1 induction in placental JEG-3 cell line
Keywords: Aryl hydrocarbon receptor; Choriocarcinoma cell line; CYP1A1; Glucocorticoid receptor; MG132; Proteasome;
Proteasome inhibition-induced p38 MAPK/ERK signaling regulates autophagy and apoptosis through the dual phosphorylation of glycogen synthase kinase 3β
Keywords: GSK3; p70S6K; MAPK; MG132; Autophagy
SUMO-2/3 conjugates accumulating under heat shock or MG132 treatment result largely from new protein synthesis
Keywords: SUMO; SUMOylation; Protein synthesis; Heat shock; MG132; 17-AAG
MG132 Alleviates Liver Injury Induced by Intestinal Ischemia/Reperfusion in Rats: Involvement of the AhR and NFκB Pathways
Keywords: AhR; MG132; liver injury; intestinal ischemia/reperfusion; cyp1a2; IκBα; NFκBp65
Deoxyelephantopin impedes mammary adenocarcinoma cell motility by inhibiting calpain-mediated adhesion dynamics and inducing reactive oxygen species and aggresome formation
Keywords: DET; deoxyelephantopin; PTX; paclitaxel; EGF; epithelial growth factor; EGFR; epithelial growth factor receptor; ROS; reactive oxygen species; FAK; focal adhesion kinase; ER; endoplasmic reticulum; JNK; c-Jun N-terminal kinase; MG132; carbobenzoxyl-l-leuc
Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography
Keywords: 53BP1; Tp53 binding protein 1; 9-1-1; RAD9-RAD1-HUS1 checkpoint clamp complex; a.a.; amino acid; ACF1; ATP-utilizing chromatin assembly and remodeling factor 1; ALC1; amplified in liver cancer 1; APLF/PALF; aprataxin and PNKP-like factor; Aprataxi
Proteasome inhibitors improve the function of mutant lysosomal α-glucosidase in fibroblasts from Pompe disease patient carrying c.546G>T mutation
Keywords: Pompe disease; Bortezomib; MG132; Proteasome inhibitor; Pharmacological chaperone;
New aldehyde and vinylsulfone proteasome inhibitors for targeted melanoma therapy
Keywords: Proteasome inhibitor; Melanoma; Aldehyde inhibitor; Vinylsulfone inhibitor; MG132;
Inhibition of NF-κB by MG132 through ER stress-mediated induction of LAP and LIP
Keywords: MG132; NF-κB; Endoplasmic reticulum (ER) stress; Unfolded protein response (UPR); C/EBPβ;
Intracellular colocalization of HAP1/STBs with steroid hormone receptors and its enhancement by a proteasome inhibitor
Keywords: Huntington's disease; Polyglutamine; Steroid; Ubiquitin; MG132; Time-lapse analysis;
MG132, a proteasome inhibitor decreased the growth of Calu-6 lung cancer cells via apoptosis and GSH depletion
Keywords: MG132; Cell cycle; Apoptosis; Calu-6 lung cancer; ROS; GSHMG132, carbobenzoxy-Leu-Leu-leucinal; ROS, reactive oxygen species; MMP, mitochondrial membrane potential (Δψm); Z-DEVD-FMK, benzyloxycarbonyl-Asp-Glu-Val-Asp-fluoromethylketone; CDK, cyclin-depend
The changes of reactive oxygen species and glutathione by MG132, a proteasome inhibitor affect As4.1 juxtaglomerular cell growth and death
Keywords: MG132; carbobenzoxy-Leu-Leu-leucinal; ROS; reactive oxygen species; SOD; superoxide dismutase; MMP (ÎΨm); mitochondrial membrane potential; FBS; fetal bovine serum; PI; propidium iodide; FITC; fluorescein isothiocyanate; H2DCFDA; 2â²,7â²-dichlorodihyd
The pharmacological NFκB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation
Keywords: MG132; BAY117082; Apoptosis; ROS; Leukemia cells
Follicular Thyroid Cancer Cell Growth Inhibition By Proteosome Inhibitor MG1321
Keywords: MG132; proteosome inhibitor; follicular thyroid cancer; glycogen synthase kinase-3β; β-catenin; FTC236