Keywords: MGL; monoacylglycerol lipase; ABH; α/β hydrolase; MG; monoacylglycerol; hMGL; monoacylglycerol lipase from Homo sapiens; bMGL; monoacylglycerol lipase from Bacillus species. H-257; Monoacylglycerol lipase; Monoglyceride lipase; Lipase cap; Conserved cap
مقالات ISI (ترجمه نشده)
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Keywords: Akt2; RAC-β serine/threonine-protein kinase; AR; aldose reductase; Bcl-2; B-cell lymphoma 2; CFL1; cofilin 1;; cMDH1; cytosolic NAD-dependent malate dehydrogenase 1; CTSK; cathepsin K; Cu-Zn SOD; Cu/Zn superoxide dismutase; DHAR2; dehydroascorbate reduct
Keywords: DC; dendritic cell; tolDCs; tolerogenic dendritic cells; PD-1; programmed cell death 1; PD-L1/PD-L2; programmed cell death ligand 1/2; 17XNL; nonlethal 17X strains; BCG; Mycobacterium bovis Bacillus Calmette Guérin; BMDCs; bone marrow-derived dendritic c
Keywords: AADAC; arylacetamide deacetylase; AChE; acetylcholinesterase; AEA; arachidonoylethanolamide; 2-AG; 2-arachidonoylglycerol; BChE; butyrylcholinesterase; BBB; blood-brain barrier; CES1; carboxylesterases 1; CES2; carboxylesterases 2; CNS; central nervous sy
Keywords: Lipid; Metabolism; Myopathy; Diet; ABHD5; α/β-Hydrolase Domain-5; AC; adenylate cyclase; anti-ACVR2B; mouse monoclonal activin receptor type IIB; ATGL; adipose triglyceride lipase; BEZ; bezafibrate; CACT; carnitine translocase; CD36; cluster of differen
Keywords: TAG; Triacylglycerol; HTS; high throughput screening; G3P; glycerol-3-phosphate; GPAT; acyl-CoA:glycerol-3-phosphate acyltransferase; LPA; lysophosphatidic acid; LPAAT; acyl-CoA:lysophosphatidic acid acyltransferase; PA; phosphatidic acid; PAP; Phosphatid
Keywords: 2-DG; 2-deoxy glucose; Akt; protein kinase B; ARDS; acute respiratory distress syndrome; Arg; arginase; BALF; broncho-alveolar lavage fluid; BCG; Bacillus Calmette-Guérin; CD; cluster of differentiation; cGAS; cyclic GMP-AMP synthase; COX-2; cyclooxyge
Keywords: 2AG; 2-Arachidonoylglycerol; AEA; Anandamide; CBD; Cannabidiol; FAAH; Fatty acid amide hydrolase; FAAH-2; Fatty acid amide hydrolase-2; MGL; Monoacylglycerol lipase; NAAA; N-Acylethanolamine acid amidase; NAPE-PLD; N-Acylphosphatidylethanolamine phospholi
Keywords: APO; apolipoprotein; ACS; acyl-CoA synthetase; ACSL; acyl-CoA synthetase, long chain; ACAT; acyl-CoA:cholesterol acyltransferase; AGPAT; acylglycerophosphate acyltransferase; ATGL; adipocyte triglyceride lipase; 3BHS1; 3-Beta-hydroxysteroid dehydrogenase;
Keywords: ACSL; acyl-CoA synthetase; ATGL; adipose triglyceride lipase; CE; cholesteryl esters; DAG; diacylglycerol; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GIR; glucose infusion rate; HSL; hormone sensitive lipase; IMTG; intramuscular triacylglycerol; MGL
Keywords: Diabetes; Cancer; Insulin; Anti-diabetics; Cannabinoid; Obesity; 2-AG; 2-arachidonoyl glycerol; ACC; acetyl-CoA carboxylase; AMPK; adenosine monophosphate-activated protein kinase; CB1R; cannabinoid 1 receptor; CB2R; cannabinoid 2 receptor; CPT-1; carniti
Keywords: Ag; antigen; APC; antigen-presenting cells; AIV; avian influenza virus; BM; bone marrow; BALT; bronchus-associated lymphoid tissue; CG; chicken galectin; cLL; chicken lung lectin; CLR; C-type lectin receptors; DC; dendritic cells; DC-SIGN; DC-specific int
G0S2a1 (G0/G1 switch gene 2a1) is downregulated by TNF-α in grass carp (Ctenopharyngodon idellus) hepatocytes through PPARα inhibition
Keywords: ATGL; adipose triglyceride lipase; HSL; hormone-sensitive lipase; MGL; monoacylglycerol lipase; ORF; open reading frame; TAG; triacylglycerol; FA; fatty acid; G0S2; G0/G1 switch gene 2; PPAR; Proliferator-Activated Receptor; TSGD; teleost-specific genome
Chlamydia pneumoniae exploits adipocyte lipid chaperone FABP4 to facilitate fat mobilization and intracellular growth in murine adipocytes
Keywords: Chlamydia pneumoniae; Adipocytes; Infection; Lipolysis; Fatty acid-binding protein 4; ATGL; adipose triglyceride lipase; HSL; hormone sensitive lipase; MGL; monoglyceride lipase; FABP4; fatty acid binding protein 4; FFAs; free fatty acids; LD; lipid dropl
CD45 in human physiology and clinical medicine
Keywords: AD; Alzheimer disease; ALL; acute lymphocytic leukemia; APC; antigen presenting cell; BMHSC; bone marrow hematopoietic stem cell; CLL; chronic lymphocytic leukemia; DLBCL; diffuse large B cell lymphoma; IS; immunological synapse; MGL; macrophage galactose
Crystal structure of mutant form Cys115His of Citrobacter freundii methionine γ-lyase complexed with l-norleucine
Keywords: MGL; methionine γ-lyase; PEG MME; polyethylene glycol monomethyl ether; PLP; pyridoxal 5â²-phosphate; Pyridoxal 5â²-phosphate-dependent methionine γ-lyase; C115H mutant form; Three-dimensional structure;
Improved respirable fraction of budesonide powder for dry powder inhaler formulations produced by advanced supercritical CO2 processing and use of a novel additive
Keywords: BDS; budesonide; DPI; dry powder inhaler; DPPC; dipalmitoylphosphatidylcholine; DSC; differential scanning calorimetry; FD; freeze-dried; HPLC; high-performance liquid chromatography; MGHPO; monoglyceride of hydrogenated palm oil; MGL; monoglyceride laura
Molecular and functional characterization of a glycosylated Galactose-Binding lectin from Mytilus californianus
Keywords: Antimicrobial activity; GalNAc/Gal-specific lectin; Glycosylated lectin; Immune system; Mytilus californianus; Carbohydrate-binding protein; 3D structure; Marine mollusks; Innate immunity; CRD; Carbohydrate Recognition Domain; CGL; Crenomytilus grayanus l
The huge-sized deinothere Deinotherium proavum (Proboscidea, Mammalia) from the Late Miocene localities Pikermi and Halmyropotamos (Greece)
Keywords: Deinotheriidae; Turolian; Taxonomy; Juvenile; Postcranial; Greece; AMPG; Athens Museum of Palaeontology and Geology (Greece); SNSB-BSPG; Staatliche Naturwissenschaftliche Sammlungen Bayerns-Bayerische Staatssammlung für Paläontologie und Geologie (Munic
Reprint of: The huge-sized deinothere Deinotherium proavum (Proboscidea, Mammalia) from the Late Miocene localities Pikermi and Halmyropotamos (Greece)
Keywords: Deinotheriidae; Turolian; Taxonomy; Juvenile; Postcranial; Greece; AMPG; Athens Museum of Palaeontology and Geology (Greece); SNSB-BSPG; Staatliche Naturwissenschaftliche Sammlungen Bayerns-Bayerische Staatssammlung für Paläontologie und Geologie (Munic
Transcriptomic and proteomic analyses of leaves from Clematis terniflora DC. under high level of ultraviolet-B irradiation followed by dark treatment
Keywords: ACL; ATP-citrate lyase; AH; aconitate hydratase; CCD; carotenoid cleavage dioxygenase; CCR; cinnamoyl-CoA reductase; CHS; chalcone synthase; COMT; caffeic acid 3-O-methyltransferase; CS; citrate synthase; CMS; chorismate synthase; C4H; trans-cinnamate 4-m
Research paperEngineered Citrobacter freundii methionine γ-lyase effectively produces antimicrobial thiosulfinates
Keywords: Methionine γ-lyase; Citrobacter freundii; Site-directed mutagenesis; Cysteine sulfoxides; Thiosulfinates; Design of pharmacological couple; Antibacterial activity; MGL; methionine γ-lyase; alliin; (±)-S-allyl-l-cysteine sulfoxide; methiin; (±)-S-methy
Anti-obesity effects of Asian dayflower, Commelina communis, in mice with high-fat diet-induced obesity and in 3T3-L1 cells
Keywords: C/EBP; CCAAT/enhancer-binding protein; PPAR; peroxisome proliferator-activated receptor; GLUT; glucose transporter; CCT; C.âcommunis tea; WAT; white adipose tissue; HFD; high-fat diet; LFD; low-fat diet; qPCR; quantitative PCR; TBP; TATA-binding protein
Novel insights into the immunomodulatory role of the dendritic cell and macrophage-expressed C-type lectin MGL
Keywords: CLR; C-type lectin receptor; DC; dendritic cell; dDC; dermal dendritic cell; GalNAc; N-acetylgalactosamine; KO; knockout; MAG; multiple antigenic peptides; MGL; macrophage galactose-type lectin; OVA; ovalbumin; PSA; prostate-specific antigen; Tn antigen;
The role of active site tyrosine 58 in Citrobacter freundii methionine γ-lyase
Keywords: MGL; methionine γ-lyase; PLP; pyridoxal 5â²-phosphate; Tyr58Phe; mutant enzyme with Tyr58 replaced by Phe; LDH; lactate dehydrogenase; HOHxoDH; d-2-hydroxyisocaproate dehydrogenase; Methionine γ-lyase; Pyridoxal 5â²-phosphate; Mutant form; Cofactor-bi
Cerebral lipid accumulation in Chanarin-Dorfman Syndrome
Keywords: ABHD5; α/β-hydrolase domain-5; ATGL; adipose triacylglycerol lipase; CDS; Chanarin-Dorfman Syndrome; CGI-58; comparative gene identification-58; Cho; choline; CIE; congenital ichthyosiform erythroderma; CK; creatine kinase; Cre; creatine; DAG; diacylg
Crystal structure of the external aldimine of Citrobacter freundii methionine γ-lyase with glycine provides insight in mechanisms of two stages of physiological reaction and isotope exchange of α- and β-protons of competitive inhibitors
Keywords: Pyridoxal 5â²-phosphate dependent enzyme; Methionine γ-lyase; Isotopic exchange of protons; Concerted mechanism; Stereoselectivity; MGL; methionine γ-lyase; PLP; pyridoxal 5â²-phosphate;
A role for glutamate-333 of Saccharomyces cerevisiae cystathionine γ-lyase as a determinant of specificity
Keywords: AAT; aspartate aminotransferase; ACCS; 1-aminocyclopropane-1-carboxylate synthase; AMPSO; N-(1,1-Dimethyl-2-hydroxyethyl)-3-amino-2-hydroxypropanesulfonic acid; bicine; 2-(Bis(2-hydroxyethyl)amino)acetic acid; CAPS; 3-(Cyclohexylamino)-1-propanesulfonic a
Short CommunicationTwo newly identified exons in human GRM1 express a novel splice variant of metabotropic glutamate 1 receptor
Keywords: mGlu; metabotropic glutamate; RACE; rapid amplification of cDNA ends; UTR; untranslated region; GPCR; G protein-coupled receptor; PLC; phospholipase C; PCR; polymerase chain reaction; RT; reverse transcription; GRM1; Metabotropic glutamate 1 receptor; mGl
Exploration of structure-function relationships in Escherichia coli cystathionine γ-synthase and cystathionine β-lyase via chimeric constructs and site-specific substitutions
Keywords: OAS; O-acetylserine; AVG; aminoethoxyvinylglycine; CBL; cystathionine β-lyase; CGL; cystathionine γ-lyase; CGS; cystathionine γ-synthase; Cth; cystathionine; Hcys; homocysteine; HO-HxoDH; d-2-Hydroxyisocaproate dehydrogenase; IPTG; Isopropyl-β-d-thiog
Activity based subcellular resolution imaging of lipases
Keywords: ABP; activity based probe; ACN; acetonitrile; ATGL; adipose triglyceride lipase; CuAAC; copper (I) catalyzed azide alkyne [3+2] cycloaddition; DIPEA; diisopropylethylamine; FA; formic acid; HSL; hormone sensitive lipase; MGL; monoglyceride lipase; TGH1; t
The association of mean glucose level and glucose variability with intensive care unit mortality in patients with severe acute pancreatitis
Keywords: MGL; mean glucose level; GV; glucose variability; ICU; intensive care unit; SAP; severe acute pancreatitis; APACHE; Acute Physiology and Chronic Health Evaluation; GLI; glycemic lability index; CI; confidence interval; OR; odds ratio; SD; standard deviati
Novel applications of nanobodies for in vivo bio-imaging of inflamed tissues in inflammatory diseases and cancer
Keywords: CDR; complementarity determining region; CEA; carcinoembryonic antigen; EGFR; epidermal growth factor receptor; HER2; human epidermal growth factor receptor 2; MAbs; monoclonal antibodies; MGL; macrophage galactose-type C-type lectins; MMR; macrophage man
Nrf2 deficiency in myeloid cells is not sufficient to protect mice from high-fat diet-induced adipose tissue inflammation and insulin resistance
Keywords: ARE; antioxidant-response element; CLS; crownlike structure; HFD; high-fat diet; HO-1; heme oxygenase-1; KO; knockout; Nrf2; NF-E2-related factor 2; OxPAPC; oxidized 1-palmitoyl-2-arachidonoyl-sn-3-glycerophosphorylcholine; Srxn1; sulfiredoxin-1; IL; inte
The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes
Keywords: MGL; monoacylglycerol lipase; bMGL; monoacylglycerol lipase from Bacillus sp. H257; hMGL; human monoacylglycerol lipase; PMSF; phenylmethylsulfonyl fluoride; SAXS; small angle X-ray scattering; RMSD; root mean square deviation; SDS-PAGE; sodium dodecyl su
Retinyl ester hydrolases and their roles in vitamin A homeostasis
Keywords: 13cIMH; 13-cis isomerohydrolase; ARAT; acyl-CoA:retinol acyltransferase; AREH; acid retinyl ester hydrolase; ATGL; adipose triglyceride lipase; BBB; blood-brain-barrier; BPL-B; brush-border phospholipase B; CE; cholesteryl ester; CEL; carboxyl ester lipas
Anti-proliferative effect of a putative endocannabinoid, 2-arachidonylglyceryl ether in prostate carcinoma cells
Keywords: AA; arachidonic acid; AEA; anandamide (arachidonylethanolamide); 2-AG; 2-arachidonoylglycerol; CBR; cannabinoid receptor; DAK; diazomethylarachidonyl ketone; EC; endocannabinoids; FAAH; fatty acid amide hydrolase; MGL; monoacylglycerol lipase; NE; 2-arach
Lipolysis - A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores
Keywords: 2-AG; 2-arachidonoyl glycerol; ABHD1-15; α/β hydrolase domain containing protein 1-15; ARF1; ADP-ribosylation factor 1; ATGL; adipose triglyceride lipase; BAT; brown adipose tissue; BiFC; bimolecular fluorescence complementation; CDS; Chanarin-Dorfman
Role of the endocannabinoid system in food intake, energy homeostasis and regulation of the endocrine pancreas
Keywords: Cannabinoids; Cannabinoid receptors; Food intake; Obesity; Insulin secretion; Islets of Langerhans; β-cells; AC; adenylate cyclase; ACEA; N-(2-chloroethyl)5,8,11,14-eicosaetraenamide; AEA; N-arachidonoyl ethanolamine; 2-AG; 2-arachidonoyl glycerol; AM251
Molecular mechanisms of human lipodystrophies: From adipocyte lipid droplet to oxidative stress and lipotoxicity
Keywords: AC; adenyl cyclase; AGPAT2; 1-acylglycerol-3-phosphate-O-acyltransferase 2; AT; adipose tissue; ATGL; adipose triglyceride lipase; BSCL; Berardinelli-Seip congenital lipodystrophy; C/EBP; CCAAT/enhancer binding protein; CGI-58; comparative gene identifica
Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomycescerevisiae
Keywords: MAG; monoacylglycerol; MGL; monoacylglycerol lipase; MGH; monoacylglycerol hydrolase; MGAT; acyl-CoA:monoacylglycerol acyltransferase; DGAT; acyl-CoA:diacylglycerol acyltransferase; EC; endocannabinoid; 2-AG; 2-arachachidonoyl glycerol; LD; lipid droplet;
Characterization of murine MGL1 and MGL2 C-type lectins: Distinct glycan specificities and tumor binding properties
Keywords: C-type lectins; MGL; Carbohydrate recognition; Antigen presenting cells;
Liver Sinusoidal Endothelial Cell Lectin, LSECtin, Negatively Regulates Hepatic T-Cell Immune Response
Keywords: CLR; C-type lectin receptors; CRD; carbohydrate recognition domain; DC; dendritic cell; DC-SIGN; dendritic cell-specific ICAM-3 grabbing nonintegrin; EGTA; ethylene glycol-bis(b-aminoethyl ether)-N,N,Nâ²,Nâ²-tetraacetic acid; IFN; interferon; IL; interl
A novel monoacylglycerol lipase inhibitor with analgesic and anti-inflammatory activity
Keywords: 1,2-Diamines; Endocannabinoids; Fatty acid amide hydrolase; FAAH; Inhibitor; Monoacyglycerol lipase; MGL
Regional distribution and effects of postmortal delay on endocannabinoid content of the human brain
Keywords: anandamide; 2-arachidonoylglycerol; brain microdissection; neurosurgical dissections; AEA; anandamide; FAAH; fatty acid amide hydrolase; MGL; monoacylglyceride lipase; 2-AG; 2-arachidonoylglycerol;
Glycomics-driven discoveries in schistosome research
Keywords: Schistosoma; Glycoprotein; Carbohydrate; Host-parasite interaction; Immunomodulation; Antigen; Glycome; Glycan; Lectin; CAA; circulating anodic antigen; CCA; circulating cathodic antigen; CD; cluster of differentiation; DC; dendritic cell; DC-SIGN; dend
Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation
Keywords: CLRs; C-type lectins; TLRs; Toll-like receptors; SEA; soluble egg antigens; DC-SIGN; dendritic cell specific ICAM-3 grabbing non-integrin; MGL; macrophage galactose-type lectin; MR; mannose receptor; poly-I:C; polyinosine-deoxycytidylic acid; Dendritic
Role of the basolateral nucleus of the amygdala in endocannabinoid-mediated stress-induced analgesia
Keywords: 2-AG; Anandamide; Antinociception; FAAH; MGL; Periaqueductal gray
Granulation tissue formation by nonspecific inflammatory agent occurs independently of macrophage galactose-type C-type lectin-1
Keywords: MGL; macrophage galactose-type calcium-type lectin; ABA-AcBSA; azobenzene arsonate-conjugated acetylated BSA; Granulation tissue formation; MGL1; Carrageenan;
Evolutionary plasticity of methionine biosynthesis
Keywords: HTA; homoserine trans-acetylase; HSK; homoserine kinase; HTS; homoserine trans-succinylase; CGS; cystathionine gamma-synthase; CBL; cystathionine beta-lyase; MGL; methionine gamma lyase; CGL; cystathionine gamma lyase; OAHS; O-acetyl homoserine sulfhydryl