Keywords: میکروسوم; Microsomes; Metabolism; Pesticides; Amphibians;
مقالات ISI میکروسوم (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: میکروسوم; αS; alpha-synuclein; PD; Parkinson's disease; ER/M; endoplasmic reticulum/microsomes; HMW; high molecular weight; SpC; spinal cord; Ctx; cortex; PreS; presymptomatic; Tg; transgenic; nTg; non-Tg; α-Synuclein; Microsomes; Endoplasmic reticulum; Oligomers
Keywords: میکروسوم; Ischemia-reperfusion injury; Non-obesogenic high-fat diet; Diabetic cardiomyopathy; Mitochondrial subpopulation; Microsomes; Oxidative stress;
Keywords: میکروسوم; fluorescence spectroscopy; amorphous; supersaturation; crystallization; microsomes;
Keywords: میکروسوم; Benzophenanthridine alkaloids; Metabolism; LC MS; Microsomes; Biotransformation
Keywords: میکروسوم; Endoplasmic reticulum; Self-assembly; ER reconstitution; In vitro assay; ER network; Microsomes; Three-way junctions;
Keywords: میکروسوم; Cytochrome P450 enzymes; Microsomal epoxide hydrolase; Microsomal glutathione-S-transferases; Microsomes; Nano liquid chromatography–tandem multiple reaction monitoring
Keywords: میکروسوم; a; membrane anchored; c; multimeric protein complex; CF; cell-free; CMC; critical micelle concentration; EF; elongation factor; ER; endoplasmic reticulum; GUVs; giant unilamellar vesicles; IF; initiation factor; LUVs; large unilamellar vesicles; MP; membr
Keywords: میکروسوم; Enzymatic kinetics; In vitro metabolism; Microsomes; Sigmoidal profile; Piplartine
Keywords: میکروسوم; Zebrafish; Embryo; Gender; CYP1A; EROD; Metabolism; Ontogeny; Microsomes
Antioxidant and pro-oxidant mechanisms of (+) catechin in microsomal CYP2E1-dependent oxidative stress
Keywords: میکروسوم; Antioxidant; Catechin; CYP2E1; Microsomes; Oxidative stress; Reactive oxygen species; b5; Cytochrome b5; CPâ; 3-carboxy-proxyl radical; CPH; 1-hydroxy-3-carboxy-2,2,5,5-tetramethylpyrrolidine; CPR; NADPH cytochrome P450 reductase; CYP2E1; Cytochrome P45
UPLC-MS/MS analysis of dextromethorphan-O-demethylation kinetics in rat brain microsomes
Keywords: میکروسوم; UPLC-MS/MS; CYP2D; Dextromethorphan-O-demethylase; Brain; Microsomes; Michaelis-Menten kinetics;
Biopharmaceutical Characterization and Oral Efficacy of a New Rapid Acting Antidepressant Ro 25-6981
Keywords: میکروسوم; oral absorption; caco-2 cells; gastrointestinal; permeability; CYP enzymes; microsomes; in vitro models; in silico modeling; metabolism; physicochemical;
In silico and in vitro inhibition of cytochrome P450 3A by synthetic stilbenoids
Keywords: میکروسوم; CYP; cytochrome P450; P450s; cytochrome P450 enzymes; RLM; rat liver microsomes; CYP3A4; Resveratrol; Nitrostilbene; Di-methoxy-nitrostilbene; Microsomes; Docking;
Antioxidants reduce reactive oxygen species but not embryotoxicity in the metabolic Danio rerio test (mDarT)
Keywords: میکروسوم; Zebrafish; Embryo; Toxicity; Reactive oxygen species; Microsomes;
Risk Assessment Using Cytochrome P450 Time-Dependent Inhibition Assays at Single Time and Concentration in the Early Stage of Drug Discovery
Keywords: میکروسوم; drug interactions; inhibition; cytochrome P450; metabolism; microsomes; protein binding;
Effects of elevated CO2 levels on subcellular distribution of trace metals (Cd and Cu) in marine bivalves
Keywords: میکروسوم; Hypercapnia; Mitochondria; Lysosomes; Microsomes; Metallothioneins; Metal-containing granules; Detoxification; Ocean acidification; Metal accumulation;
In vitro CYP-mediated drug metabolism in the zebrafish (embryo) using human reference compounds
Keywords: میکروسوم; Zebrafish; Cytochrome; Microsomes; Ontogeny; Sex; LC-MS;
Species differences of 11beta-hydroxysteroid dehydrogenase type 2 function in human and rat term placenta determined via LC-MS/MS
Keywords: میکروسوم; LC-MS/MS; Placenta; Glucocorticoid; Steroids; CRH; 11beta-hydroxysteroid dehydrogenase; Microsomes; Rat; Human;
Constitutive expression of cytochrome P450 in foetal and adult porcine livers-Effects of body weight
Keywords: میکروسوم; Ontogeny; Birth-Weight; Age; Life-stage; Microsomes; CYP; qPCR;
Effects of duration of phenytoin administration on mRNA expression of cytochrome P450 and P-glycoprotein in the liver and small intestine of rats
Keywords: میکروسوم; Phenytoin; Cytochromes P450; Microsomes; mRNA; Liver
QSARs for estimating intrinsic hepatic clearance of organic chemicals in humans
Keywords: میکروسوم; Quantitative structure-activity relationship; Biotransformation; Clearance (CLINT); Hepatocytes; Microsomes;
Evaluation of the impact of 16-dehydropregnenolone on the activity and expression of rat hepatic cytochrome P450 enzymes
Keywords: میکروسوم; 16-dehydropregnenolone; CYP450; Cocktail; Pharmacokinetics; Microsomes; Real time RT-PCR;
In Vitro Metabolism and Stability of the Actinide Chelating Agent 3,4,3-LI(1,2-HOPO)
Keywords: میکروسوم; Chelation therapy; stability; microsomes; ADME; protein binding; cytochrome P450; intestinal absorption;
Electrochemical generation of selegiline metabolites coupled to mass spectrometry
Keywords: میکروسوم; Selegiline; Electrochemistry; Mass spectrometry; Microsomes; Dielectric barrier discharge ionization;
Human microsomal cyttrochrome P450-mediated reduction of oxysophocarpine, an active and highly toxic constituent derived from Sophora flavescens species, and its intestinal absorption and metabolism in rat
Keywords: میکروسوم; Oxysophocarpine; CYP450; Absorption; Metabolism; Microsomes; In situ
Evaluation of the stereoselective biotransformation of permethrin in human liver microsomes: Contributions of cytochrome P450 monooxygenases to the formation of estrogenic metabolites
Keywords: میکروسوم; Cytochrome P450; Biotransformation; Permethrin; Pyrethroids; Estrogenic activity; Microsomes;
Modulation of CYP2D6 and CYP3A4 metabolic activities by Ferula asafetida resin
Keywords: میکروسوم; Asafetida; Dextromethorphan; CYP3A4; CYP2D6; Microsomes; Metabolism; Interaction
Alcohol-induced oxidative stress in rat liver microsomes: Protective effect of Emblica officinalis
Keywords: میکروسوم; Alcohol; CYP-450; Emblica officinalis; Microsomes; Oxidative stress
The cytochrome P450-catalyzed metabolism of levomepromazine: a phenothiazine neuroleptic with a wide spectrum of clinical application
Keywords: میکروسوم; Levomepromazine; Metabolism; Human CYP; Microsomes; Supersomes; Specific inhibitors;
Metabolism of 20-hydroxyvitamin D3 by mouse liver microsomes
Keywords: میکروسوم; 20-Hydroxyvitamin D3; Microsomes; Hydroxylation; Cytochrome P450; Liver;
Abiraterone inhibits 1α,25-dihydroxyvitamin D3 metabolism by CYP3A4 in human liver and intestine in vitro
Keywords: میکروسوم; 1α,25(OH)2D3; 1α,25-dihydroxyvitamin D3; P450; cytochrome P450; VDR; vitamin D receptor; LC-MS/MS; liquid chromatography-tandem mass spectrometry; HLM; human liver microsomes; HIM; human intestinal microsomes; CRPC; castration-resistant prostate can
Absolute quantification of UGT1A1 in various tissues and cell lines using isotope label-free UPLC-MS/MS method determines its turnover number and correlates with its glucuronidation activities
Keywords: میکروسوم; UGT; uridine 5â²-diphospho-glucuronosyltransferase (UDP-glucuronosyltransferase); CYP; cytochrome P450; UPLC; ultra performance liquid chromatography; MRM; multiple reaction monitoring; DP; declustering potential; CE; collision energy; CXP; collision cel
Antimutagenic and antioxidant activity of Ficus benghalensis stem bark and Moringa oleifera root extract
Keywords: میکروسوم; Lipid peroxidation; Microsomes; Antimutagenic; Antioxidant; Salmonella typhimurium;
Biotransformation of trans-1-chloro-3,3,3-trifluoropropene (trans-HCFO-1233zd)
Keywords: میکروسوم; Microsomes; Biotransformation; Rabbit; Rat; Haloolefins; trans-HCFO-1233zd; Mercapturic acids
Metabolism of a potent neuroprotective hydrazide
Keywords: میکروسوم; Metabolites; Alzheimer’s; Neuroprotective; Microsomes; Hydrazines
In vitro pharmacokinetic profile of a benzopyridooxathiazepine derivative using rat microsomes and hepatocytes: Identification of phases I and II metabolites
Keywords: میکروسوم; Benzopyridooxathiazepine; Hepatocytes; Metabolism; Microsomes; Orbitrap mass spectrometry; Validation
Therapeutic modulation of cannabinoid lipid signaling: Metabolic profiling of a novel antinociceptive cannabinoid-2 receptor agonist
Keywords: میکروسوم; Biotransformation; Cannabinoid; Half-life; Liver; Microsomes; Metabolism; Mouse; Seven‐transmembrane receptor
Assigning atropisomer elution orders using atropisomerically enriched polychlorinated biphenyl fractions generated by microsomal metabolism
Keywords: میکروسوم; Polychlorinated biphenyls; Microsomes; Atropisomeric enrichment; Gas chromatography
Metabolism of a Serotonin-4 Receptor Partial Agonist 4-{4-[4-Tetrahydrofuran-3-yloxy)-Benzo[d]Isoxazol-3-yloxymethyl]-Piperidin-1-ylmethyl}-Tetrahydropyran-4-ol (TBPT): Identification of an Unusual Pharmacologically Active Cyclized Oxazolidine Metabolite
Keywords: میکروسوم; metabolism; microsomes; protein binding; mass spectrometry; hepatic metabolism
New insights into the role of cytochrome P450 reductase (POR) in microsomal redox biology
Keywords: میکروسوم; Cytochrome P450; Squalene monooxygenase; Heme oxygenase; Cytochrome b5; Microsomes; 7-Dehydrocholesterol reductase
Quercetin attenuates ethanol-derived microsomal oxidative stress: Implication of haem oxygenase-1 induction
Keywords: میکروسوم; Quercetin; Haem oxygenase-1; Ethanol; Oxidative stress; Microsomes; Cytochrome P450 2E1;
Maternal obesity alters feto-placental cytochrome P4501A1 activity
Keywords: میکروسوم; Human placenta; Maternal obesity; Cytochrome P4501A; Cytosol; Microsomes; CYP; cytochrome P450; CPR; cytochrome P450 reductase; HFD; high fat diet; BMI; body mass index;
Species specific differences in the in vitro metabolism of the flame retardant mixture, Firemaster® BZ-54
Keywords: میکروسوم; Microsomes; Cytosol; Fish; Metabolism; Flame retardant; Firemaster;
Effect of a membrane permeable metal chelator on iron and hemoglobin-mediated lipid oxidation in washed fish muscle
Keywords: میکروسوم; TPEN; Washed cod; Lipid oxidation; Hemoglobin; Metal chelators; Microsomes;
Evaluation of Hepatic Clearance Prediction Using In Vitro Data: Emphasis on Fraction Unbound in Plasma and Drug Ionisation Using a Database of 107 Drugs
Keywords: میکروسوم; in vitro-in vivo correlations (IVIVC); hepatocytes; microsomes; clearance; intrinsic clearance; protein binding; prediction; precision; bias;
Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry
Keywords: میکروسوم; UDP-glucuronosyltransferase; Microsomes; Liquid chromatography; Tandem mass spectrometry; Drug metabolism;
IPG-strips versus off-gel fractionation: Advantages and limits of two-dimensional PAGE in separation of microsomal fractions of frequently used plant species and tissues
Keywords: میکروسوم; APS; ammonium persulfate; BAC; benzyldimethyl-n-hexadecylammonium chloride; CTAB; Cetyltrimethylammonium Bromide; CCB; Colloidal Coomassie Blue; RT; room temperature; SB-12; lauryl-sulfobetaine; TEMED; tetramethylethylendiamin; TFE; tri-fluorethanol; TMD;
In Vitro-In Vivo Extrapolation of Clearance: Modeling Hepatic Metabolic Clearance of Highly Bound Drugs and Comparative Assessment with Existing Calculation Methods
Keywords: میکروسوم; disposition; microsomes; hepatic clearance; metabolic clearance; unbound fraction; computational ADME; in vitro-in vivo extrapolation; IVIVE; pharmacokinetics; PBPK modeling;
Comparative Assessment of In Vitro-In Vivo Extrapolation Methods used for Predicting Hepatic Metabolic Clearance of Drugs
Keywords: میکروسوم; disposition; microsomes; clearance; unbound fraction; computational ADME; in vitro-in vivo extrapolation; in vitro-in vivo correlation; IVIVE; pharmacokinetics; PBPK modeling;