miRNAs and lncRNAs in reproductive development
Keywords: miRNAs; lncRNAs; Reproduction; Anther development; Pistil development; Sex determination;
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Research paperHuman cytomegalovirus microRNA miR-US25-1-5p inhibits viral replication by targeting multiple cellular genes during infection
Keywords: miRNAs; microRNAs; HCMV; human cytomegalovirus; siRNA; small interference RNA; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; MEM; minimal essential medium; MOI; multiplicity of infection; hpi; hours post infection; RT; reverse transcr
Genetics meets epigenetics: Genetic variants that modulate noncoding RNA in cardiovascular diseases
Keywords: MiRNAs; Long noncoding RNAs; Cardiovascular diseases; Common genetic variants;
Bioinformatics of cardiovascular miRNA biology
Keywords: MiRNAs; Multiple sequence alignment; RNA secondary structure; Database; Omics; Heart;
Research ReportmiR-29c regulates NAV3 protein expression in a transgenic mouse model of Alzheimer׳s disease
Keywords: miRNAs; microRNAs; AD; Alzheimer׳s disease; 3â² UTR; 3â²-untranslated regions; NAV3; neurone navigator 3; BACE1; beta-site APP-cleaving enzyme 1; miR-29c; Alzheimer׳s disease; NAV3 protein; microRNAs; APPswe/PSÎE9 mice;
Let-7c overexpression inhibits dengue virus replication in human hepatoma Huh-7 cells
Keywords: Dengue virus; miRNAs; Let-7c; BACH1;
Non-coding RNAs in gastric cancer
Keywords: ncRNAs; non-coding RNAs; sncRNAs; small ncRNAs; lncRNAs; long ncRNAs; snoRNAs; small nucleolar RNAs; piRNAs; Piwi-associated RNAs; miRNAs; microRNAs; tiRNAs; transcription initiation RNAs; lincRNAs; long intergenic ncRNAs; GC; gastric cancer; nts; nucleot
Identification and expression of the target gene emx2 of miR-26a and miR-26b in Paralichthys olivaceus
Keywords: ATM; ataxia telangiectasia mutated; BCES; Beidaihe Central Experimental Station; CDS; coding DNA sequence; emx2; empty spiracles homeobox 2; miRNAs; microRNAs; Mw; molecular weight; NGS; next-generation sequencing; ORF; open reading frame; pI; isoelectric
Noncoding RNAs as regulators of cardiomyocyte proliferation and death
Keywords: miRNAs; microRNAs; lncRNA; long non-coding RNA; LAD; left anterior descending coronary artery; hCMPCs; human Cardiomyocyte Progenitor Cells; CSCs; Cardiac Stem Cells; MI; Myocardial Infarction; MFN1; Mitofusin 1; I/R; Ischemia/Reperfusion; BNIP3; BCL2/ade
2-iodohexadecanal Inhibits thyroid cell growth in part through the induction of let-7f microRNA
Keywords: Thyroid; Iodolipids; Iodine; Iodohexadecanal; miRNAs; miR-let-7f; miR-138;
miR-1182 attenuates gastric cancer proliferation and metastasis by targeting the open reading frame of hTERT
Keywords: TERT; telomerase reverse transcriptase; miRNAs; microRNAs; miRISCs; miRNA-induced silencing complexes; AGO; argonaute; MREs; miRNA recognition elements; ORF; open reading frame; miR-1182; hTERT; Gastric cancer; Proliferation; Metastasis;
MiR-30a attenuates immunosuppressive functions of IL-1β-elicited mesenchymal stem cells via targeting TAB3
Keywords: miRNAs; microRNAs; CCNE2; cyclin E2; COX2; cyclooxygenase 2; IL; interleukin; MSCs; mesenchymal stem cells; PE; preeclampsia; TAB3; transforming growth factor-β-activated kinase 1 binding protein 3; NF-κB; nuclear factor κB; MAPK; mitogen-activated pro
MicroRNAs in osteosarcoma
Keywords: OS; osteosarcoma; miRNAs; microRNAs; CSCs; cancer stem cells; RNA pol; RNA polymerase; DGCR8; DiGeorge syndrome critical gene 8; RISC; RNA-induced silencing complex; Exp 5; exportin 5; Ago; argonaute; MREs; miRNA recognition elements; APE1; apurinic/apyri
The 5â² and 3â² ends of alphavirus RNAs - Non-coding is not non-functional
Keywords: Translation regulation; Polyadenylation; mRNA capping; Viral pathogenesis; miRNAs; Protein-RNA interactions;
Circulating levels of miR-150 are associated with poorer outcomes of A/H1N1 infection
Keywords: miRNAs; Pandemic influenza A/H1N1; Critically ill patients; Circulating microRNAs; miR-150; Influenza
Changes in microRNAs associated with Twist-1 and Bcl-2 overexpression identify signaling pathways
Keywords: miRNAs; Twist-1; Bcl-2; EMT; VM
MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma
Keywords: Glioma; MiRNAs; Liposomes; Chlorotoxin; MicroRNA-21; Anti-angiogenesis
Posttranscriptional silencing of the lncRNA MALAT1 by miR-217 inhibits the epithelial–mesenchymal transition via enhancer of zeste homolog 2 in the malignant transformation of HBE cells induced by cigarette smoke extract
Keywords: Cigarette smoke extract (CSE); miRNAs; lncRNAs; Epithelial–mesenchymal transition (EMT)
Predicting human miRNA target genes using a novel computational intelligent framework
Keywords: miRNAs; miRNA targets; Genetic Algorithm; Evolutionary computation; Support Vector Machines; Fuzzy logic
ROBO3 promotes growth and metastasis of pancreatic carcinoma
Keywords: Pancreatic cancer; ROBO3; Invasion; Metastasis; miR-383; EMT; endothelial to mesenchymal transition; SFRP; Secreted Frizzled Related Protein; PDAC; pancreatic ductal adenocarcinoma; TGF-β; transforming growth factor-β; miRNAs; MicroRNAs;
Let-7g induces granulosa cell apoptosis by targeting MAP3K1 in the porcine ovary
Keywords: Let-7g; MAP3K1; FoxO1; Granulosa cell; Apoptosis; miRNAs; mircoRNAs; 3â² UTR; 3â²-untranslated regions; GCs; granulosa cells; PTEN; phosphatase and tensin homolog; PBS; phosphate buffered saline; PI; propidium iodide; BSA; bovine serum albumin; DAPI; AT
Contribution of bioinformatics prediction in microRNA-based cancer therapeutics
Keywords: MicroRNAs; MiRNAs; Therapy; Bioinformatics; Computational model; Pancreatic cancer
Non-coding RNAs: An emerging player in DNA damage response
Keywords: DNA damage response; Non-coding RNAs; miRNAs; lncRNAs
The expression profiling and ontology analysis of noncoding RNAs in peritoneal fibrosis induced by peritoneal dialysis fluid
Keywords: CAPD; continuous ambulatory peritoneal dialysis; PDF; peritoneal dialysis fluid; ncRNAs; non-coding RNAs; miRNAs; microRNAs; lncRNAs; long non-coding RNAs; ceRNA; competitive endogenous RNAs; MREs; miRNA response elements; EMT; epithelial-to-mesenchymal t
Pathologic function and therapeutic potential of exosomes in cardiovascular disease
Keywords: Exosomes; Cardiomyopathy; Cardiac remodeling; Stem cells; miRNAs
The biological functions of miRNAs: lessons from in vivo studies
Keywords: miRNAs; animal models; paralogs; network motifs; buffering
Interferon-γ in foam cell formation and progression of atherosclerosis
Keywords: IFN-γ; interferon-γ; IFNGR; IFN-γ receptor; VSMC; vascular smooth muscle cell; IL; interleukin; LPS; lipopolysaccharide; TNF-α; tumor necrosis factor-α; STAT; signal transducer and activator of transcription; NF-κB; nuclear factor-κB; TLR; Toll-lik
miR-27b inhibits LDLR and ABCA1 expression but does not influence plasma and hepatic lipid levels in mice
Keywords: miRNAs; miR-27b; LDLR; ABCA1; Lipid homeostasis; Atherosclerosis
PI3K/Akt signaling in osteosarcoma
Keywords: OS; osteosarcoma; PI3K; phosphatidylinositol 3-kinase; PTEN; phosphatase and tensin homolog; mTOR; mammalian target of rapamycin; RTKs; receptor tyrosine kinases; PDGFR; platelet-derived growth factor receptor; IGF1R; insulin-like growth factor 1 receptor
Novel aberrant genetic and epigenetic events in Friedreich׳s ataxia
Keywords: FRDA; Friedreich׳s ataxia; FXN; frataxin; ISC; iron-sulphur cluster; hPDL; human periodontal ligament; CASP3; active caspase-3; DNMT; DNA methyltransferase; CpG; cytosine phosphate group guanine; TSS; transcription start site; UP; upstream GAA repetiti
Research ReportMidbrain dopamine neurons in Parkinson׳s disease exhibit a dysregulated miRNA and target-gene network
Keywords: CT; cycle threshold; DA; dopamine; FC; fold change; SN; substantia nigra; LMD; laser microdissection; IPA; ingenuity pathway analysis; miRNAs; Dopamine neurons; Parkinson׳s disease; Laser capture microdissection; IPA;
miRNAs in atherosclerotic plaque initiation, progression, and rupture
Keywords: atherosclerosis; miRNAs; inflammation; shear stress; vulnerable plaque
Downregulation of microRNA-451 in non-alcoholic steatohepatitis inhibits fatty acid-induced proinflammatory cytokine production through the AMPK/AKT pathway
Keywords: Non-alcoholic fatty liver; Non-alcoholic steatohepatitis; MicroRNAs; MicroRNA-451; Cab39/MO25; Inflammation; AMPK; adenosine monophosphate activated protein kinase; DEGs; differentially expressed genes; GEO; gene expression omnibus; GOBPs; gene ontology b
Drug resistance-related microRNAs in hematological malignancies: Translating basic evidence into therapeutic strategies
Keywords: miRNAs; MicroRNAs; Multidrug resistance; Hematological malignancies; Biomarkers; Therapeutic targets
The miRnome of Fasciola hepatica juveniles endorses the existence of a reduced set of highly divergent micro RNAs in parasitic flatworms
Keywords: Fasciola hepatica; Newly excysted juveniles; miRNAs; tRNA halves
ReviewMother's nutritional miRNA legacy: Nutrition during pregnancy and its possible implications to develop cardiometabolic disease in later life
Keywords: CVD; cardiovascular disease; miRNAs; microRNAs; HF diet; high-fat diet; LP diet; low-protein diet; mRNA; messenger RNA; Ppar-α; peroxisome proliferator-activated receptor alpha; cpt-1a; carnitine palmitoyltransferase 1A; Igf2; insulin-like grow factor 2;
Opposing roles of miR-21 and miR-29 in the progression of fibrosis in Duchenne muscular dystrophy
Keywords: α-SMA; α-smooth muscle actin; COL1A1; collagen type I alpha 1; COL3A1; collagen type III alpha 1; COL6A1; collagen type VI alpha 1; DMD; Duchenne muscle dystrophy; ECM; extracellular matrix; ERK; extracellular signal-regulated kinase; FBN1; fibrillin 1;
Microdissecting the role of microRNAs in the pathogenesis of prostate cancer
Keywords: miRNAs; PCa; androgen-dependent; androgen-independent; hormone-sensitive; castration-resistant
MicroRNA-mediated immune modulation as a therapeutic strategy in host-implant integration
Keywords: Macrophages; Foreign body reaction; Immune response; Osteolysis; TLR; Pro-inflammatory cytokines; miRNAs;
Platelet miRNAs and cardiovascular diseases
Keywords: Platelet; miRNAs; Cardiovascular diseases; Genes
Lipid-Induced Hepatocyte-Derived Extracellular Vesicles Regulate Hepatic Stellate Cells via MicroRNA Targeting Peroxisome Proliferator-Activated Receptor-γ
Keywords: Extracellular Vesicles; Hepatic Stellate Cell; Lipotoxicity; Liver Fibrosis; miRNAs; B2M; β2-microglobulin; CDAA; choline-deficient l-amino acid; CSAA; choline supplemented l-amino acid; CTGF; connective tissue growth factor; fsDMEM; Dulbecco's modifie
Targeting strategies on miRNA-21 and PDCD4 for glioblastoma
Keywords: GBM; glioblastoma multiforme; miRNAs; microRNAs; PDCD4; programmed cell death 4; EMT; epithelial-mesenchymal transition; JNK; Jun N-terminal protein kinase; PTEN; phosphatase and tensin homolog; PI3K/AKT; phosphatidylinositol-3 kinase/Akt; MAPK/ERK; mit
MicroRNA expression profiles differentiate chronic pain condition subtypes
Keywords: CCPC; complex chronic pain condition; CNS; central nervous system; FM; fibromyalgia; HC; healthy controls; IBS; irritable bowel syndrome; IL-1ra; interleukin 1 receptor antagonist; IL-8; interleukin 8; miRNAs; microRNAs; TMD; temporomandibular disorder; T
Autophagy regulation in heme-induced neutrophil activation is associated with microRNA expression on transfusion-related acute lung injury
Keywords: autophagy; miRNAs; neutrophil; reactive oxygen species; transfusion-related acute lung injury
Association between SNPs in miRNA-machinery genes and chronic hepatitis B in the Chinese Han population
Keywords: miRNAs; microRNAs; HBV; hepatitis B virus; SNPs; single nucleotide polymorphisms; CHB; chronic hepatitis B; HRM; high resolution melting method; HCC; hepatocellular carcinoma; VDR; vitamin D receptor; TLR3; Toll-like receptor 3; cDNA; complementary DNA; U
Association of single nucleotide polymorphisms of ERCC1 and XPF with colorectal cancer risk and interaction with tobacco use
Keywords: miRNAs; microRNAs; ERCC1; excision repair cross-complementation group 1; XPF; xeroderma pigmentosum-complementation group F; ERCC2; excision repair cross-complementation group 2; ERCC3; excision repair cross-complementation group 3; NER; nuclear excision
Genome-wide mRNA and miRNA expression data analysis to screen for markers involved in sarcomagenesis in human chondrosarcoma cell lines
Keywords: SD, standard deviation; PCA, principal component analysisHuman chrondrosarcoma; mRNA expression; miRNAs; Microarray; Bioinformatics
ReviewmicroRNAs: A connection between cholesterol metabolism and neurodegeneration
Keywords: miRNAs; Cholesterol metabolism; Neurodegenerative disorders;
Potential relationship and clinical significance of miRNAs and Th17 cytokines in patients with multiple myeloma
Keywords: miRNAs; Th17 cytokines; Multiple myeloma;
miR-326 and miR-26a, two potential markers for diagnosis of relapse and remission phases in patient with relapsing-remitting multiple sclerosis
Keywords: AUC; area under the curve; CNS; central nervous system; DAVID; database for annotation, visualization and integrated discovery; hADSCs; human adipose tissue-derived stem cells; KEGG; Kyoto Encyclopedia of Genes and Genomes; miRNAs; microRNAs; MS; multiple