Cytotoxic effect of TDZ on human cervical cancer cells
Keywords: پتانسیل غشای میتوکندری; Thiadiazol; Mitochondrial membrane potential; HeLa cells; Anticancer;
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Resveratrol induces mitochondrial respiration and apoptosis in SW620 colon cancer cells
Keywords: پتانسیل غشای میتوکندری; ÎΨm; mitochondrial membrane potential; 2-DG; 2-deoxyglucose; 5-FU; 5-fluorouracil; ANT A; antimycin A; COX; cytochrome c oxidase; ERα; estrogen receptor alpha; ERβ; estrogen receptor beta; ERRα; estrogen-related receptor alpha; ETO; etomoxir; FCCP; c
Novel platinum(IV) complexes conjugated with a wogonin derivative as multi-targeted anticancer agents
Keywords: پتانسیل غشای میتوکندری; TBTU; O-(benzotriazol-1-yl)-N,N,Nâ²,Nâ²-tetramethyluronium tetrafluoroborate; DCM; dichloromethane; TEA; triethylamine; DMF; N/Nâ²-dimethylformamide; DMSO; dimethylsulfoxide; PBS; phosphate buffer solution; SGC7901; human gastric carcinoma cell line; H
Feruloylserotonin inhibits hydrogen peroxide-induced melanogenesis and apoptosis in B16F10 and SK-Mel-2 melanoma cells
Keywords: پتانسیل غشای میتوکندری; Feruloylserotonin; ROS; Melanogenesis; Apoptosis; Mitochondrial membrane potential;
Addition of insulin-like growth factor I to the maturation medium of bovine oocytes subjected to heat shock: effects on the production of reactive oxygen species, mitochondrial activity and oocyte competence
Keywords: پتانسیل غشای میتوکندری; Thermoprotection; Heat stress; DNA fragmentation; Mitochondrial membrane potential; ROS production;
The neuroprotective effects of Berberine against amyloid β-protein-induced apoptosis in primary cultured hippocampal neurons via mitochondria-related caspase pathway
Keywords: پتانسیل غشای میتوکندری; AD; Alzheimer's disease; Aβ; β-amyloid protein; DMEM; Dulbecco's modified eagle's medium; FBS; fetal bovine serum; PDL; poly-d-lysine; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliu-m bromide; DMSO; dimethyl sulfoxide; PVDF; Polyvinylide
Non-enzymatic oxidized metabolite of DHA, 4(RS)-4-F4t-neuroprostane protects the heart against reperfusion injury
Keywords: پتانسیل غشای میتوکندری; ÎΨm; mitochondrial membrane potential; 4-F4t-NeuroP; 4(RS)-4-F4t-neuroprostane; n-3 PUFA; n-3 polyunsaturated fatty acids; Ca2+; Calcium; CsA; cyclosporine A; CypD; cyclosphilin D; DHA; docosahexaenoic acid; ECG; electrocardiogram; EPA; eicosapentaenoic
Proanthocyanidins from Uncaria rhynchophylla induced apoptosis in MDA-MB-231 breast cancer cells while enhancing cytotoxic effects of 5-fluorouracil
Keywords: پتانسیل غشای میتوکندری; Uncaria rhynchophylla; Proanthocyanidins; 5-Fluorouracil; Breast cancer; Apoptosis; AAE/g dw; ascorbic acid equivalent/g dry weight; ABTS; 2,20-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid; CI; combination index; CIwt; weighted average; DCF-DA; 2â²,
16-Hydroxycleroda-3, 13-dien-15, 16-olide inhibits the proliferation and induces mitochondrial-dependent apoptosis through Akt, mTOR, and MEK-ERK pathways in human renal carcinoma cells
Keywords: پتانسیل غشای میتوکندری; Polyalthia longifolia; 16-Hydroxycleroda-3,13-dien-15,16-olide; Renal cell carcinoma; Apoptosis; AO/EB; acridine orange and ethidium bromide; Bcl-2; B cell lymphoma 2; ccRCC; clear cell renal cell carcinoma; CD; 16-hydroxycleroda-3,13-dien-15,16-olide; ER
The photodynamic action of pheophorbide a induces cell death through oxidative stress in Leishmania amazonensis
Keywords: پتانسیل غشای میتوکندری; AA; antimycin A; CCCP; cyanide m-chlorophenylhydrazone; DAF-FM diacetate; 4-amino-5-methylamino-2â²,7â²-difluoro fluoresceÃn; DMSO; dimethylsulfoxide; DPPP; diphenyl-1-pyrenylphosphine; DTNB; 2,2â²-dinitro-5,5â²-dithiobenzoic acid; FBS; fetal bovine
Gen-27, a newly synthesized flavonoid, inhibits glycolysis and induces cell apoptosis via suppression of hexokinase II in human breast cancer cells
Keywords: پتانسیل غشای میتوکندری; BCA; bicinchoninic acid; Cyt c; cytochrome c; DAPI; 4â²,6-diamidino-2-phenylindole; DCFH/DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DMSO; dimethylsulfoxide; FBS; Fetal bovine serum; HKII; hexokinase II; LDHA; lactate dehydrogenase; MMP; mitochon
Liqustri lucidi Fructus inhibits hepatic injury and functions as an antioxidant by activation of AMP-activated protein kinase in vivo and in vitro
Keywords: پتانسیل غشای میتوکندری; AMPK; LKB1; Ligustri lucidi Fructus; Liver injury; CCl4; ACC; acetyl-CoA carboxylase; AICAR; aminoimidazole-carboxamide-β-d-ribofuranoside; AMPK; AMP-activated protein kinase; FACS; fluorescence-activated cell sorter; GSH; glutathione; H&E; hematoxylin a
Hypoxia decreases ROS level in human fibroblasts
Keywords: پتانسیل غشای میتوکندری; BNIP3; BCL2/adenovirus E1B 19Â kDa protein-interacting protein 3; CM-H2DCFDA; chloromethyl-2â²,7â²-dichlorodihydrofluorescein diacetate; ÎÏm; mitochondrial membrane potential; DTNB; 5,5'-dithiobis-(2-nitrobenzoic acid); FCCP; carbonyl cyanide p-(tri
Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts
Keywords: پتانسیل غشای میتوکندری; Pancreatic cancer; Mitotic arrest; DNA damage; Apoptosis; c-Jun N-terminal kinase; Trichodermin; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma extra long; CDK; cyclin-dependent kinase; Cdc; cell division cycle; DSBs; double-strand breaks; DUSP1; dual
Synchronism in mitochondrial ROS flashes, membrane depolarization and calcium sparks in human carcinoma cells
Keywords: پتانسیل غشای میتوکندری; ÎΨm; mitochondrial membrane potential; DCF-DA; 2â²,7â²-dichlordihydrofluorescein diacetate; mito Ca2 +;  mitochondrial Ca2 +;  mitoROS; mitochondrial ROS; ROS; reactive oxygen species; MPTP; mitochondrial permeability transition pore; RIRR; ROS-in
NAP1L1 regulates NF-κB signaling pathway acting on anti-apoptotic Mcl-1 gene expression
Keywords: پتانسیل غشای میتوکندری; NF-κB; nuclear factor-κB; Bcl-2; B cell lymphoma protein 2; Bcl-xl; Bcl-2-related protein long form of Bcl-x; Mcl-1; myeloid cell leukemia 1; Bax; bcl-2-associated X protein; NAPs; nucleosome assembly proteins; NAP1L; NAP1 like protein; ÎÎÎζ; diacyl
The cycloartane triterpenoid ADCX impairs autophagic degradation through Akt overactivation and promotes apoptotic cell death in multidrug-resistant HepG2/ADM cells
Keywords: پتانسیل غشای میتوکندری; 3-MA; 3-methyladenine; ADCX; 25-O-acetyl-7,8-didehydrocimigenol 3-O-beta-D-xylopyranoside; TCM; traditional Chinese medicine; HCC; hepatocellular carcinoma; ABC; ATP-binding cassette; ULK1; unc-51-like kinase 1; HCQ; hydroxychloroquine; CTSB; cathepsin B;
Mevalonolactone disrupts mitochondrial functions and induces permeability transition pore opening in rat brain mitochondria: Implications for the pathogenesis of mevalonic aciduria
Keywords: پتانسیل غشای میتوکندری; Mevalonic aciduria; Mevalonate kinase deficiency; Mevalonic acid; Mevalonolactone; Mitochondrial function; Mitochondrial permeability transition; ACO; aconitase; Alm; alamethicin; BSA; bovine serum albumin; CAC; citric acid cycle; CCCP; carbonyl cyanide 3
CQ synergistically sensitizes human colorectal cancer cells to SN-38/CPT-11 through lysosomal and mitochondrial apoptotic pathway via p53-ROS cross-talk
Keywords: پتانسیل غشای میتوکندری; CRC; Colorectal cancer; CQ; chloroquine; 3-MA; 3-methyladenine; ROS; reactive oxygen species; LMP; lysosomal membrane potential; âÏm; mitochondrial membrane potential; NAC; N-acetyl-L-cysteine; Vit-C; vitamin C; DMSO; dimethyl sulfoxide; Pep-A; pepstat
Identity and function of a cardiac mitochondrial small conductance Ca2+-activated K+ channel splice variant
Keywords: پتانسیل غشای میتوکندری; APD; action potential duration; BSA; bovine serum albumin; CaMBD; Ca2+ calmodulin binding domain; COX; cytochrome c oxidase; CYPPA; N-cyclohexyl-N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-4-pyrimidinamine; DCEB; 5,6-dichloro-1-ethyl-1,3-dihydro-2H-benzimid
The ATM kinase inhibitor KU-55933 provides neuroprotection against hydrogen peroxide-induced cell damage via a γH2AX/p-p53/caspase-3-independent mechanism: Inhibition of calpain and cathepsin D
Keywords: پتانسیل غشای میتوکندری; AIF; apoptosis inducing factor; A-T; ataxia telangiectasia syndrome; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related protein; CGC; cerebellar granule cells; DNA-PK; DNA-dependent protein kinase; Dox; doxorubicin; DSB; doubl
Metal complexes targeting the Translocator Protein 18Â kDa (TSPO)
Keywords: پتانسیل غشای میتوکندری; ACBP; acyl coenzyme-A binding protein; AIF; apoptosis inducing factor; ANT; Adenine Nucleotide Translocase; B; boron; BDZ; benzodiazepine; BFC approach; bifunctional chelate approach; BNCT; Boron Neutron Capture Therapy; CBR; Central-type Benzodiazepine R
Mitochondrial transition ROS spike (mTRS) results from coordinated activities of complex I and nicotinamide nucleotide transhydrogenase
Keywords: پتانسیل غشای میتوکندری; mTRS; mitochondrial transition ROS spike; OXPHOS; oxidative phosphorylation; NNT; nicotinamide nucleotide transhydrogenase; palm-CoA; palmitoyl-coenzyme A;  âΨmt; mitochondrial membrane potential; VO2; oxygen consumption; mTRS; ROS; Membrane potential
ATP-consuming processes in hepatocytes of river lamprey Lampetra fluviatilis on the course of prespawning starvation
Keywords: پتانسیل غشای میتوکندری; Lamprey; Hepatocytes; Prespawning starvation; Metabolic depression; Mitochondrial membrane potential; Protein synthesis; Na+-K+-pump; Aminotransferases;
In vitro exposure of human spermatozoa to bisphenol A induces pro-oxidative/apoptotic mitochondrial dysfunction
Keywords: پتانسیل غشای میتوکندری; BPA; Bisphenol A; BWW; Biggers Whitten and Wittingham; CASA; Computer-Aided Semen Analysis; DMSO; Dimethylsulfoxide; ÎΨm; Mitochondrial membrane potential; MSR; MitoSOX red; FITC; Fluorescein isothiocyanate; PBS; Phosphate-buffered saline; ROS; Reactive
Stimulation by pro-apoptotic valinomycin of cytosolic NADH/cytochrome c electron transport pathway-Effect of SH reagents
Keywords: پتانسیل غشای میتوکندری; cyto-c; cytochrome c; MOM; mitochondrial outer membrane; MIS; mitochondrial intermembrane space; MIM; mitochondrial inner membrane; ÎΨm; mitochondrial membrane potential; Îp; electrochemical proton gradient; porin; voltage dependent anion channel; Sox;
Rescue of mitochondrial function in parkin-mutant fibroblasts using drug loaded PMPC-PDPA polymersomes and tubular polymersomes
Keywords: پتانسیل غشای میتوکندری; UA; ursolic acid; UCA; ursocholanic acid; PMPC-PDPA; poly(2-(methacryloyloxy)ethylphosphorylcholine)-poly(2-diisopropylamino)ethylmethacrylate); ATP; adenosine tri-phosphate; DMSO; dimethyl-sulfoxide; PD; Parkinson's disease; UDCA; ursodeoxycholic aci
Characterization of functional variables in epididymal alpaca (Vicugna pacos) sperm using imaging flow cytometry
Keywords: پتانسیل غشای میتوکندری; Epididymal sperm; Acrosome integrity; Mitochondrial membrane potential; Lipid peroxidation; Flow cytometry; Vicugna pacos;
Down-regulation of BNIP3 by olomoucine, a CDK inhibitor, reduces LPS- and NO-induced cell death in BV2 microglial cells
Keywords: پتانسیل غشای میتوکندری; Aβ; amyloid β; BH3; Bclâ2 homology domain 3; BNIP3; Bcl-2/adenovirus E1B 19âkDa-interacting protein 3; CNS; central nervous system; cPTIO; carboxy-PTIO; CDK; cyclin-dependent kinase; DMEM; Dulbecco's modified Eagle medium; HD; Huntington's disea
Stimulation of adenosine A2A receptors reduces intracellular cholesterol accumulation and rescues mitochondrial abnormalities in human neural cell models of Niemann-Pick C1
Keywords: پتانسیل غشای میتوکندری; Niemann-Pick C; Adenosine A2A receptor; Cholesterol; Mitochondrial membrane potential; Neuroblastoma cell line; Oligodendroglial cell line;
High content analysis assay for prediction of human hepatotoxicity in HepaRG and HepG2 cells
Keywords: پتانسیل غشای میتوکندری; DILI; drug-induced liver injury; GLP; good laboratory practice; HCA; high content analysis; ROS; reactive oxygen species; GSH; glutathione; MMP; mitochondrial membrane potential; MP; membrane permeability; CM-H2DCFDA; 5-(and-6)-chloromethyl-2â²,7â²-dich
PINK1/Parkin-mediated mitophagy play a protective role in manganese induced apoptosis in SH-SY5Y cells
Keywords: پتانسیل غشای میتوکندری; Mn; manganese; MnCl2; manganese chloride; PD; Parkinson's disease; MMP/ÎΨm; mitochondrial membrane potential; ROS; reactive oxygen species; MMT; methylcyclopentadienyl manganese tricarbonyl; ER stress; endoplasmic reticulum stress; MTP; mitochondrial po
Sinuleptolide inhibits proliferation of oral cancer Ca9-22 cells involving apoptosis, oxidative stress, and DNA damage
Keywords: پتانسیل غشای میتوکندری; Soft corals; Sinuleptolide; Oral cancer; Apoptosis; DNA damage; Mitochondrial membrane potential;
STED super-resolution imaging of mitochondria labeled with TMRM in living cells
Keywords: پتانسیل غشای میتوکندری; Cationic fluorescent dye; Mitochondrial inner membrane; Mitochondrial membrane potential; Oxidative phosphorylation system;
Protective effects of physical exercise on MDMA-induced cognitive and mitochondrial impairment
Keywords: پتانسیل غشای میتوکندری; MDMA; 3, 4-methylendioxymethamphetamine; MWM; Morris water maze test; ROS; reactive oxygen species; MMP; mitochondrial membrane potential; IP; intraperitoneally; S.C; subcutaneously; ETC; electrone transport chain; HEPES; 4-2-hydroxyethyl piperazineethane
Influence of the APOE genotype on hepatic stress response: Studies in APOE targeted replacement mice and human liver cells
Keywords: پتانسیل غشای میتوکندری; AD; Alzheimer's disease; APOE; apolipoprotein E; ATP; adenosine triphosphate; ATP5A1; ATP synthase subunit alpha, mitochondrial; B2M; beta-2 microglobulin; BAX; BCL2-associated X protein; BCL2; B-cell leukemia/lymphoma 2; BiP; binding immunoglobulin prote
Silibinin triggers yeast apoptosis related to mitochondrial Ca2+ influx in Candida albicans
Keywords: پتانسیل غشای میتوکندری; MIC; minimum inhibitory concentration; YPD; yeast extract peptone dextrose; YM; yeast mold; ROS; reactive oxygen species; PBS; phosphate buffered saline; H2DCFDA; 2â²,7â²-dichlorodihydrofluorescein diacetate; RR; ruthenium red; PI; propidium iodide; PPB
Effective killing of cancer cells and regression of tumor growth by K27 targeting sulfiredoxin
Keywords: پتانسیل غشای میتوکندری; BHA; butylated hydroxyanisol; DMSO; dimethyl sulfoxide; FITC; fluorescein isothiocyanate; H2O2; hydrogen peroxide; ÎΨm; mitochondrial membrane potential; MPTP; mitochondrial permeability transition pore; NAC; N-acetyl cysteine; NAO; nonyl acridine orang
Curcumin hampers the antitumor effect of vinblastine via the inhibition of microtubule dynamics and mitochondrial membrane potential in HeLa cervical cancer cells
Keywords: پتانسیل غشای میتوکندری; Curcumin; Vinblastine; Microtubule; Mitochondrial membrane potential; ROS, Antitumor activityROS, Reactive oxygen species; MMP, Mitochondrial membrane potential; NAC, N-acetyl cysteine; PI, Propidium iodide; DAPI, 6-diamidino-2-phenylindole; DCF-DA, 2′,7′
mTOR inhibition attenuates glucose deprivation-induced death in photoreceptors via suppressing a mitochondria-dependent apoptotic pathway
Keywords: پتانسیل غشای میتوکندری; mTOR; Mitochondrial membrane potential; Rapamycin; Photoreceptor cells; Oxidative stress; DRP1
Analysis of mitochondrial structure and function in the Drosophila larval musculature
Keywords: پتانسیل غشای میتوکندری; ATP; adenosine triphosphate; AEL; after egg laying; CMT2A; Charcot-Marie-Tooth Type 2A; ConA; concanavalin A; Drp1; dynamin-related protein; DOA; dominant optic atrophy; GFP; green fluorescent protein; IFM; indirect flight muscle; IMF; intermyofibrill
Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer
Keywords: پتانسیل غشای میتوکندری; HNC; head and neck cancer; DCA; dichloroacetate; CDDP; cisplatin; OXPHOS; oxidative phosphorylation; PDK2; pyruvate dehydrogenase kinase 2; PDHE1α; pyruvate dehydrogenase isoform E1α; ROS; reactive oxygen species; ÎΨm; mitochondrial membrane potential
Involvement of mitochondrial permeability transition pore (mPTP) in cardiac arrhythmias: Evidence from cyclophilin D knockout mice
Keywords: پتانسیل غشای میتوکندری; CaWs; Ca2+ waves; FCCP; carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone; CsA; cyclosporin A; CypD KO; CypD knockout mouse model; DHPR, α1 subunit of L-type Ca channel; dihydropyridine receptor; Cai2+; intracellular Ca2+; I/R; ischemia/reperfusion;
Protein binding and anticancer activity studies of ruthenium(II) polypyridyl complexes toward BEL-7402 cells
Keywords: پتانسیل غشای میتوکندری; Ru (II) polypyridyl complexes; Cytotoxicity in vitro; Reactive oxygen species; Mitochondrial membrane potential; Western blot analysis
Blue light emitting diode induces apoptosis in lymphoid cells by stimulating autophagy
Keywords: پتانسیل غشای میتوکندری; Light emitting diode; Apoptosis; ROS; Mitochondrial membrane potential; Autophagy;
Synthesis, characterization and anticancer effect of the ruthenium (II) polypyridyl complexes on HepG2 cells
Keywords: پتانسیل غشای میتوکندری; Ruthenium (II) polypyridyl complexes; Cytotoxicity in vitro; Cell invasion; Reactive oxygen species; Mitochondrial membrane potential; Western blot analysis;
Candesartan cilexetil attenuated cardiac remodeling by improving expression and function of mitofusin 2 in SHR
Keywords: پتانسیل غشای میتوکندری; LVH; left ventricular hypertrophy; VSMC; vascular smooth muscle cell; EH; essential hypertension; Mfn2; mitofusin 2; SHR; spontaneously hypertensive rat; WKY; Wistar-Kyoto rat; ÎÏm; mitochondrial membrane potential; ROS; reactive oxygen species; BW; bod
Deoxynivalenol inhibits proliferation and induces apoptosis in human umbilical vein endothelial cells
Keywords: پتانسیل غشای میتوکندری; Deoxynivalenol; HUVECs; Mitochondrial membrane potential; Cell cycle; Apoptosis
Phosphorylation of the mitochondrial ATP-sensitive potassium channel occurs independently of PKCε in turtle brain
Keywords: پتانسیل غشای میتوکندری; Kir6.2 subunit; Mitochondria; Rhodamine-123; Mitochondrial membrane potential; Channel arrest; Anoxia tolerance
Potential hepatic toxicity of buprofezin at sublethal concentrations: ROS-mediated conversion of energy metabolism
Keywords: پتانسیل غشای میتوکندری; TCA cycle; tricarboxylic acid cycle; ROS; reactive oxygen species; mtDNA; mitochondrial DNA; SCO1; cytochrome c oxidase assembly protein; COX17; cytochrome c oxidase copper chaperone; CS; citrate synthase; OGDH; oxoglutarate (alpha-ketoglutarate) dehydrog