Keywords: MCC; ADAM; a disintegrin and metalloproteinase; AKT; protein kinase B; APAF 1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; ATG; autophagy protein; BAK; Bcl 2 homologous antagonist/killer; BAX; Bcl-2 associated -X protein; Bcl-2; B-
مقالات ISI MCC (ترجمه نشده)
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Keywords: MCC; Atherosclerosis; Cardiovascular diseases; Cell cycle; Proliferation; Pulmonary hypertension; Restenosis; Signaling pathway; Vascular smooth muscle cells; ACE; angiotensin converting enzyme; aFGF; acidic FGF; Ang II; angiotensin II; AP-1; activating protei
Keywords: MCC; AP-1; activator protein 1; APC; antigen-presenting cells; ARE; AU-rich element; ASK; Apoptosis Signal regulating Kinase; ATF-2; Activating Transcription Factor 2; CRE; Cyclic AMP Responsive Element; CBP; CREB binding protein; CsA; ciclosporin A; ERK; Extr
Keywords: MCC; CD 14; cluster determinant 14; TLR; toll like receptor; TNF; tumor necrotic factor; EGFR; epidermal growth factor receptor; ODE; ordinary differential equation; PCA; principal component analysis; NIK; NFκB-inducing kinase; MKK; mitogen kinase kinases; PI
Keywords: MCC; ACTDs; autoimmune connective tissue diseases; SLE; systemic lupus erythematosus; RA; rheumatoid arthritis; SSc; systemic sclerosis; SS; Sjögren's syndrome; MCTD; mixed connective tissue disease; TLRs; IL-1R-like receptors; DAMPs; danger-associated molecu
Keywords: MCC; Abl; Abelson leukemia proto-oncogene; ADAP; adhesion and degranulation promoting adapter protein (Fyb, SLAP-130); Asc; apoptosis-associated speck-like protein containing a CARD; BCR; B-cell receptor; C3G; Crk SH3 domain-binding guanine nucleotide exchange
Keywords: MCC; Asia; India; Watershed; Poverty; Equity; Environmental services; CEDAW; Convention on Elimination of all forms of Discrimination Against Women; DDP; Desert Development Programme; DNK; Danji Khera (Village 1); DKK; Dudaji Ka Khera (Village 2); DPAP; Drough
Involvement of NADPH oxidase 1 in UVB-induced cell signaling and cytotoxicity in human keratinocytes
Keywords: MCC; UV; Ultraviolet; ROS; Reactive Oxygen Species; O2-; Superoxide; OH; Hydroxyl radical; H2O2; Hydrogen peroxide; NOX; NADPH oxidase; PBS; Phosphate-buffered saline; DNA; Deoxyribonucleic acid; RNA; Ribonucleic acid; DPI; Diphenyleneiodonium; NAC; N-acetyl c
Age-dependent regulation of antioxidant genes by p38α MAPK in the liver
Keywords: MCC; Akt; Protein kinase B; AP-1; Activator protein-1; ASK1; Apoptosis signal-regulating kinase 1; ATF2; activating transcription factor 2;; ChIP; Chromatin immunoprecipitation;; DEN; Diethyl nitrosamine;; EGFR; Epidermal growth factor receptor; G6PDH; Glucose
Genetic polymorphisms of pharmacogenomic VIP variants in the Yi population from China
Keywords: MCC; ASW; African ancestry in southwestern USA; ATP; Adenosine triphosphate; CEU; Utah residents with Northern and Western European ancestry; CHB; Han Chinese in Beijing, China; CHD; Chinese in Metropolitan Denver, Colorado, USA; EAsia; EastAsia; GIH; Gujarati
ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway
Keywords: MCC; Akt; oncogene in the transforming retrovirus, AKT8; AP-1; activator protein 1; ARAF; v-raf murine sarcoma 3611 viral oncogene homologue; ASK1; apoptosis signal-regulating kinase 1; BCL2; B-cell lymphoma 2; BCL-XL; B-cell lymphoma extra large; BRAF; v-raf
N-Acetyl-chitobiose ameliorates metabolism dysfunction through Erk/p38 MAPK and histone H3 phosphorylation in type 2 diabetes mice
Keywords: MCC; ALX; alloxan; COS; chitooligosaccharide; Erk; extracellular signal-regulated kinase; (GlcNAc)2; N-acetyl-chitobiose (PubChem CID: 160244); H&E; haematoxylin and eosin; HOMA-IR; homeostasis model assessment of insulin resistance; IC50; the 50% inhibitory c
The renal protective effects of Anoectochilus roxburghii polysaccharose on diabetic mice induced by high-fat diet and streptozotocin
Keywords: MCC; ARP; Anoectochilus roxburghii polysaccharose; ECM; extracellular matrix; FN; fibronection; GBM; glomerular basement membrane; HFD; high-fat diet; ICR; Institute of Cancer Research; MCP-1; monocyte chemoattractant protein-1; MKK; mitogen-activated protein
Epigallocatechin gallate and mitochondria-A story of life and death
Keywords: MCC; ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; ALT; alanine aminotransferase; AMP; adenosine monophosphate; AP-1; activator protein-1; ASK1; apoptosis signal-regulating kinase 1; ATP; adenosine triphosphate; Bax; BCL2-Associated X Protein; Bc
The genome-wide identification of mitogen-activated protein kinase kinase (MKK) genes in Yesso scallop Patinopecten yessoensis and their expression responses to bacteria challenges
Keywords: MCC; MKK; Patinopecten yessoensis; Micrococcus luteus and Vibrio anguillarum infection; Innate immune; MAPK signaling cascade;
MPTP activates ASK1-p38 MAPK signaling pathway through TNF-dependent Trx1 oxidation in parkinsonism mouse model
Keywords: MCC; 6-OHDA; 6-hydroxydopamine; ADAM17; ADAM metallopeptidase domain 17; AMS; 4-acetamido-4â²-maleimidylstilbene-2, 2â²-disulfonic acid, disodium salt; ASK1; Apoptosis signal-regulating kinase 1; CIB1; Calcium and integrin-binding protein 1; C (in figure); V
TPL2 signalling: From Toll-like receptors-mediated ERK1/ERK2 activation to Cystic Fibrosis lung disease
Keywords: MCC; ABIN-2; A20-binding inhibitor of NF-κB 2; CF; Cystic Fibrosis; CFTR; Cystic Fibrosis transmembrane conductance regulator; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kinase; GSH; glutathione; IFN; Interferon; IKK; I-kappa-
Myrsine seguinii ethanolic extract and its active component quercetin inhibit macrophage activation and peritonitis induced by LPS by targeting to Syk/Src/IRAK-1
Keywords: MCC; Ms-EE; ethanolic extract of Myrsine seguinii; PGE2; prostaglandin E2; NO; nitric oxide; COX; cyclooxygenase; iNOS; inducible NO synthase; (TNF)-α; tumour necrosis factor; ERK; extracellular signal-related kinase; TLR; toll-like receptors (TLR); MAPK; mit
Identification of conserved and novel microRNAs in Manduca sexta and their possible roles in the expression regulation of immunity-related genes
Keywords: MCC; Posttranscriptional regulation; Illumina sequencing; Lepidoptera; Insect immunity; Target site prediction; Alk; anaplastic lymphoma kinase; AMP; antimicrobial peptides; ANKRD54; ankyrin repeat domain 54; Aop; anterior open; aPKC; atypical protein kinase C
Age-related activation of MKK/p38/NF-κB signaling pathway in lung: From mouse to human
Keywords: MCC; ALI; acute lung injury; ANOVA; analysis of variance; BALF; bronchoalveolar lavage fluid; COPD; chronic obstructive pulmonary disease; DAB; 3, 3â²-diaminobenzidine tetrahydrochloride; DAPI; 4â², 6-diamidino-2-phenylindole; DMSO; dimethyl sulphoxide; ERKs
Intracellular mobility and nuclear trafficking of the stress-activated kinase JNK1 are impeded by hyperosmotic stress
Keywords: MCC; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; JNK; c-Jun N-terminal kinase; Imp; importin; NLS; nuclear localization sequence; NTS; nuclear translocation signal; FRAP; fluorescence recovery after photobleaching; GFP;
Genetic variability of glutathione S-transferase enzymes in human populations: Functional inter-ethnic differences in detoxification systems
Keywords: MCC; GSTs; Glutathione S-Transferases; LoF; Loss-of-Function; MAPEG; Membrane-Associated Proteins involved in Eicosanoid and Glutathione metabolism; GSTA; GST alpha class; GSTM; GST mu class; GSTP; GST pi class; GSTT; GST theta class; GSTK; GST kappa class; GS
Identification of mitogen-activated protein kinase kinase gene family and MKK-MAPK interaction network in maize
Keywords: MCC; Maize; Mitogen-activated protein kinase; MKK; Phylogenetic analysis; Expression analysis;
Development of peptide inhibitor as a therapeutic agent against head and neck squamous cell carcinoma (HNSCC) targeting p38α MAP kinase
Keywords: MCC; MAPK; mitogen activated protein kinase; HNSCC; head and neck squamous cell carcinoma; MKK; MAPK kinase; MKKK; MKK kinase; LB; Luria-Bertani; IPTG; isopropyl-Ã-d-galactosidase; DLS; dynamic light scattering; ATF; activated transcription factor; NPP; 4-nit
Rit subfamily small GTPases: Regulators in neuronal differentiation and survival
Keywords: MCC; CA; constitutively active; cAMP; cyclic adenosine monophosphate; CaM; calmodulin; CCI; controlled cortical impact; CREB; cAMP response element binding protein; CRIB; Cdc42/Rac interactive binding; DA; dopamine; DAT; dopamine transporter; DN; dominant nega
Identification and characterization of bi-thiazole-2,2â²-diamines as kinase inhibitory scaffolds
Keywords: MCC; MAPK; mitogen-activated protein kinase; JD; JNK Docking; ERK; extracellular signal signal-regulated kinase; JNK; c-Jun N-terminal kinase; MKK; MAPK kinase; GST; glutathione S-transferase; GSH; glutathione; JIP; JNK-interacting protein; DCX; doublecortin X
Wnt5a activates THP-1 monocytic cells via a β-catenin-independent pathway involving JNK and NF-κB activation
Keywords: MCC; FBS; fetal bovine serum; FHC; ferritin heave chain; HAECs; human aortic endothelial cells; IFN; interferon; IKK; IkB kinase; JNK; c-Jun N-terminus kinase; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinase; MKK; mitogen-activated-protein kina
Methanol extract of Osbeckia stellata suppresses lipopolysaccharide- and HCl/ethanol-induced inflammatory responses by inhibiting Src/Syk and IRAK1
Keywords: MCC; Os-ME; methanol extract of Osbeckia stellata; PGE2; prostaglandin E2; NO; nitric oxide; COX; cyclooxygenase; iNOS; inducible NO synthase; TNF-α; tumor necrosis factor-alpha; ERK; extracellular signal-related kinase; TLR; toll-like receptor; MAPK; mitogen
Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)
Keywords: MCC; AP-1; activator protein-1; ASC; apoptosis-associated speck-like protein containing a CARD domain; ASK; apoptosis signal-regulating kinase; ATM; Ataxia Telangiectasia Mutated; ATR; ATM and Rad 3-related; BRCA1; breast cancer 1; CARD; caspase activation and
Dynamics and regulation of lipid droplet formation in lipopolysaccharide (LPS)-stimulated microglia
Keywords: MCC; LD; lipid droplet; TG; triglyceride; TLR4; Toll-like receptor 4; LPS; lipopolysaccharides; ADRP; adipocyte differentiation-related protein; CNS; central nervous system; NO; nitric oxide; MAPK; mitogen-activated protein kinases; JNK; c-Jun N-terminal kinas
Activation of the JNK pathway by nanosecond pulsed electric fields
Keywords: MCC; nsPEF; nanosecond pulsed electric field; JNK; c-Jun N-terminal kinase; MAP kinase; mitogen-activating protein kinase; MKK; mitogen-activating protein kinase kinase; Nanosecond pulsed electric field; Electroporation; JNK; c-Jun; MAP kinase;
Brazilian propolis-derived components inhibit TNF-α-mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes
Keywords: MCC; aP2; adipocyte fatty acid-binding protein 4; EMM; molecular mechanics energy; FBS; fetal bovine serum; JNK; c-Jun-NH2-terminal kinase; MAPK; mitogen-activated protein kinase; MKK; mitogen-activated protein kinase kinase; MM-PBSA; molecular mechanics Poiss
Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active
Keywords: MCC; AdV; adenovirus or adenoviral; ET-1; endothelin-1; FPLC; fast protein liquid chromatography; MBP; myelin basic protein; MKK; MAPK kinase; PMA; phorbol 12-myristate 13-acetate; PTP; protein Tyr-phosphatase; SDS-PAGE; sodium dodecyl sulphate-polyacrylamide
Non-canonical functions of RGS proteins
Keywords: MCC; AC; adenylyl cyclase; CHO; Chinese hamster ovary; CNK1; connector enhancer of KSR1; CREB; cAMP-response element binding protein; DH; dbl-homology; DMAP1; Dnmt1-associated protein 1; EGF; epidermal growth factor; eIF; eukaryotic initiation factor; ERK; ext
c-Jun N-terminal kinase (JNK) signaling: Recent advances and challenges
Keywords: MCC; Ago; Argonaute; DELFIA; Dissociation Enhanced Lathanide Fluoro-Immuno Assay; D-JNKI-1; cell-permeable JIP1-derived JNK inhibitory peptide-1 (D-amino acids); ELISA; enzyme-linked immunosorbent assays; ERK; extracellular signal-regulated kinase (ERK); FITC;
The role of protein synthesis in cell cycling and cancer
Keywords: MCC; Cell cycle; Elongation factor 2; Elongation factor 2 kinase; Apoptosis; Cancer; AMPK; AMP-activated Kinase; cAMP; cyclic AMP; PKA; Protein Kinase A; FLIP; FLICE-Like Inhibitor Protein; XIAP; X-linked Inhibitor of Apoptosis; EF2; Elongation Factor 2; cdc2/
Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5
Keywords: MCC; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ASK1; apoptosis signal-regulating kinase 1; Cd; cadmium; CM-H2DCFDA; 5-(and-6)-chloromethyl-2â²,7â²-dichlorodihydrofluorescein diacetate; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco'
Neuroprotection against ischemic brain injury by a small peptide inhibitor of c-Jun N-terminal kinase (JNK) via nuclear and non-nuclear pathways
Keywords: MCC; c-Jun N-terminal protein kinase; JNK; JNK interacting protein-1; JIP-1; Tat-JBD; cerebral ischemia/reperfusion; AP-1; activator-protein 1; BSA; bovine serum albumin; DTT; dithiothreitol; Fasl; Fas ligand; GluR6; glutamate receptor 6; h-DMEM; high-glucose
A cross-talk between RNA splicing and signaling pathway alters Fas gene expression at post-transcriptional level: Alternative splicing of Fas mRNA in the leukemic U937 cells
Keywords: MCC; ASF/SF2; alternative splicing factor/splicing factor 2; CCD; charge coupled device; hnRNPA1; heterogeneous nuclear ribonucleoprotein A1; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; MKK; mitogen-activated protein kinase kinase; RR
Kinase signaling cascades in the mitochondrion: a matter of life or death
Keywords: MCC; AKAP; A-kinase anchoring protein; Akt/PKB; protein kinase B; DAG; diacylglycerol; ERK; extracellular signal-regulated protein kinase; GSK3β; glycogen synthase kinase 3β; IP3; inositol triphosphate; JNK/SAPK; c-Jun N terminal kinase/stress-activated prot
MAPK signalling pathways as molecular targets for anti-inflammatory therapy-from molecular mechanisms to therapeutic benefits
Keywords: MCC; ARE; AU-rich element; ASK; Apoptosis Signal regulating Kinase; ATF-2; Activating Transcription Factor 2; CRE; Cyclic AMP Responsive Element; ERK; Extracellular signal regulated kinase; iNOS; inducible Nitric Oxide Synthase; JNK; c-Jun N-terminal Kinase; L
The p38 SAPK pathway is required for Ha-ras induced in vitro invasion of NIH3T3 cells
Keywords: MCC; u-PA; urokinase plasminogen activator; AP-1; activating protein 1; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; CAT; chloramphenicol acetyl transferase; ERK; extracellular signal-regulated kinase; SAPK; stress-activated protein kinas
Role of protein turnover in the activation of p38 mitogen-activated protein kinase in rat pinealocytes
Keywords: MCC; AA-NAT; arylalkylamine-N-acetyltransferase; Actin; actinomycin; c-lact; clasto-lactacystin β-lactone; Cyclo; cycloheximide; DMEM; Dulbecco's modified Eagle's medium; GAPDH; glyceraldehyde-3-phosphate-dehydrogenase; JNK; c-Jun amino terminal kinase; MAPK;
MKK3/6-p38 MAPK negatively regulates murine MMP-13 gene expression induced by IL-1β and TNF-α in immortalized periodontal ligament fibroblasts
Keywords: MCC; IL-1β; Interleukin-1 beta; TNF-α; Tumor necrosis factor-alpha; MAPK; Mitogen-activated protein kinase; MKK; Mitogen-activated protein kinase kinase; siRNA; Silencing RNA; JNK; c-Jun N-terminal kinase; ERK; Extracellular-regulated protein kinase; MMP-13;
Marker genes to predict sensitivity to FK228, a histone deacetylase inhibitor
Keywords: MCC; HDAC; histone deacetylase; TSA; trichostatin A; SAHA; suberoylanilide hydroxamic acid; SC-6; SC-6-JCK; LC-6; LC-6-JCK; nude; BALB/c nu/nu; MKP-1; mitogen-activated protein kinase phosphatase 1; IL-8; interleukin-8; MAPK; mitogen-activated protein kinase;