دانلود مقالات ISI درباره MPP + + ترجمه فارسی

Copper sulfate pretreatment prevents mitochondrial electron transport chain damage and apoptosis against MPP+-induced neurotoxicity

Keywords: MPP +; Parkinson's disease; MPP+; Copper sulfate; Cytochrome c oxidase; Cu/Zn-superoxide dismutase; Metallothionein;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Acylated and unacylated ghrelin confer neuroprotection to mesencephalic neurons

Keywords: MPP +; AG; acylated; BBB; blood-brain-barrier; CCCP; carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone; GHSR1a; growth hormone secretagogue receptor 1a; GOAT; ghrelin O-acyltransferase; mDA; mesencephalic dopaminergic; NeuN; neuronal nuclei; OCR; oxygen con

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The significance of rotational behavior and sensitivity of striatal dopamine receptors in hemiparkinsonian rats: A comparative study of lactacystin and 6-OHDA

Keywords: MPP +; DA; dopamine; DOPAC; dihydroxyphenylacetic acid; HVA; homovanilic acid; MPP+; 1-methyl-4-phenylpyridinium ion; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; SN; substantia nigra; SNc; substantia nigra pars compacta; SNr; s

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Research PaperNrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson's disease

Keywords: MPP +; GPx; glutathione peroxidase; HO-1; heme oxygenase-1; MPP+;  1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Nrf2; nuclear factor erythroid 2 related factor 2; PD; Parkinson's disease; SNpc; substantia nigra pars compacta;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Cooperative synthesis of dopamine by non-dopaminergic neurons as a compensatory mechanism in the striatum of mice with MPTP-induced Parkinsonism

Keywords: MPP +; AADC; aromatic l-amino acid decarboxylase; DA; dopamine; DAT; dopamine membrane transporter; DBH; dopamine beta-hydroxylase; FR; Fluoro-Ruby; HPLC-ED; high performance liquid chromatography with electrochemical detection; l-DOPA; l-3,4-dihydroxyphenylalan

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Interaction between the zebrafish (Danio rerio) organic cation transporter 1 (Oct1) and endo- and xenobiotics

Keywords: MPP +; ADME; absorption, distribution, metabolism and excretion; ASP+; 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide; DAPI; 4′,6-diamidino-2-phenylindole; DBT; dibutyltin chloride; DMEM; Dulbecco's modified eagle's medium; HEK239; human embryonic kid

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Photoactivation of ERK/CREB/VMAT2 pathway attenuates MPP+-induced neuronal injury in a cellular model of Parkinson's disease

Keywords: MPP +; PD; Parkinson's disease; SNpc; substantia nigra pars compacta; DA; dopamine; MPTP; 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine; MPP+; 1-methyl-4-phenylpyridinium; VMAT2; vesicular monoamine transporter 2; LPLI; low-power laser irradiation; Aβ; amyloi

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Paraquat and maneb co-exposure induces noradrenergic locus coeruleus neurodegeneration through NADPH oxidase-mediated microglial activation

Keywords: MPP +; DA neuron; dopaminergic neuron; DHE; dihydroethidium; DSP-4; N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride; Iba-1; ionized calcium binding adaptor molecule-1; iNOS; inducible nitric oxide synthase; LC/NE neuron; noradrenergic locus coeruleus

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Measuring inhibition of monoamine reuptake transporters by new psychoactive substances (NPS) in real-time using a high-throughput, fluorescence-based assay

Keywords: MPP +; Dopamine transporter; Norepinephrine transporter; Serotonin transporter; Fluorescent monoamine substrate; Designer drugs; Drug screening; 2C-B; 2,5-dimethoxy-4-bromophenethylamine; 4-FA; 4-fluoroamphetamine; 5-APB; 5-(2-aminopropyl)benzofuran; 25B-NBOMe;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

Different Involvement of OAT in Renal Disposition of Oral Anticoagulants Rivaroxaban, Dabigatran, and Apixaban

Keywords: MPP +; drug interactions; solute transporters; organic anion transporters (OAT); pharmacokinetics/pharmacodynamics; renal transport; BCRP; breast cancer resistance protein; CCK8; cholecystokinin-8; E217βG; estradiol 17β-D-glucuronide; E-sul; estrone 3-sulfate;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

Targeted methylation sequencing reveals dysregulated Wnt signaling in Parkinson disease

Keywords: MPP +; Epigenetic regulation; Neurodegenerative diseases; Environmental toxins; Neurogenesis; PD; Parkinson disease; DA; dopaminergic; CGIs; CpG islands; T-DMRs; tissue differential methylation regions; TSS; transcription start sites; MPP+; 1-methyl-4-phenylpyri

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Opening of ATP-sensitive K+ (KATP) channels enhance hydroxyl radical generation induced by MPP+ in rat striatum

Keywords: MPP +; DA; dopamine; OH; hydroxyl radical; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+;  1-methyl-4-phenylpyridinium ion; DHBA; dihydroxybenzoic acid; MAO; monoamine oxidase; Cromakalim; Nicorandil; ATP-sensitive K+ (KATP) channel; 1-Methyl-4-pheny

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

PKC phosphorylates residues in the N-terminal of the DA transporter to regulate amphetamine-induced DA efflux

Keywords: MPP +; A; alanine; CaMKII; calcium-calmodulin protein kinase II; D; aspartate; DA; dopamine; DAT; DA transporter; ERK; extracellular signal-regulated kinase; GFP; green fluorescent protein; MPP+; [3H]1-methyl-4-phenylpyridinium; PKA; protein kinase A; PKC; prote

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Pinocembrin attenuates MPP+-induced neurotoxicity by the induction of heme oxygenase-1 through ERK1/2 pathway

Keywords: MPP +; Parkinson's disease; Pinocembrin; MPP+; Heme oxygenase-1; Neuroprotection;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Chloroquine and Hydroxychloroquine Are Novel Inhibitors of Human Organic Anion Transporting Polypeptide 1A2

Keywords: MPP +; chloroquine; hydroxychloroquine; solute carrier transporters; organic anion transporters; organic anion-transporting polypeptide transporters; organic cation transporters; drug interaction; inhibition; OATP1A2; SLCs; solute carrier transporters; CQ; chlor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Estrogen protects against dopamine neuron toxicity in primary mesencephalic cultures through an indirect P13K/Akt mediated astrocyte pathway

Keywords: MPP +; ERα; estrogen receptor alpha; GSH; glutathione; IGF-1; insulin-like growth factor 1; TGF-β1; transforming growth factor beta 1; ApoE; apolipoprotein; GDNF; glial cell line-derived neurotrophic factor; MPP+; 1-methyl-4-phenylpyridinium; Estrogen; Neuropr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Alteration of nuclear factor-kappaB pathway promote neuroinflammation depending on the functions of estrogen receptors in substantia nigra after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment

Keywords: MPP +; PD; Parkinson's disease; SN; substantia nigra; Iba1; ionized calcium binding adaptor molecule 1; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; TNF-α; tumor necrosis factor-alpha; b.w.; body weight; GFAP; glial fib

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Research articleInsulin on activation of autophagy with integrins and syndecans against MPP+-induced α-synuclein neurotoxicity

Keywords: MPP +; α-Syn, SNCA; α-synuclein; Cox-2; cyclooxygenase-2; ILK; integrin-linked kinase; ITGAV; integrin αV; ITGB3; integrin β3; LDH; lactate dehydrogenase; MAP1LC3; microtubule-associated protein 1 light chain 3; MPP+; 1-Methyl-4-phenyl pyridinium; SDC1; synd

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

MTERF2 contributes to MPP+-induced mitochondrial dysfunction and cell damage

Keywords: MPP +; Mitochondrial transcription termination factors 2 (MTERF2); Mitochondrial dysfunction; Parkinson's disease; MPP+; Protein transport; CCCP;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Cyclophilin B protects SH-SY5Y human neuroblastoma cells against MPP+-induced neurotoxicity via JNK pathway

Keywords: MPP +; Apoptosis; Cyclophilin B; JNK; MPP+; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Protection against MPP+-induced neurotoxicity in SH-SY5Y cells by tormentic acid via the activation of PI3-K/Akt/GSK3β pathway

Keywords: MPP +; Parkinson's disease; Tormentic acid; Neuroprotection; MPP+; SH-SY5Y cells; PI3-K/Akt/GSK3

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Characterizations of a synthetic pituitary adenylate cyclase-activating polypeptide analog displaying potent neuroprotective activity and reduced in vivo cardiovascular side effects in a Parkinson's disease model

Keywords: MPP +; Neurodegeneration; Neurodegenerative disorders; PACAP; Dopaminergic neuron survival; SH-SY5Y neuroblastoma cell survival; Vasodilation; Cq; quantification cycle; Eu3; europium(III) cryptate; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease

Keywords: MPP +; AAV2/9; adeno-associated viral vector pseudotype2/9; DA; dopamine; hα-syn; p.A53T human α-synuclein; MPTP; 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine; N/OFQ; nociceptin/orphanin FQ; NOP; N/OFQ peptide receptor; 6-OHDA; 6-hydroxydopamine; p-α-syn; pho

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Parkinson's disease-related gene variants influence pre-mRNA splicing processes

Keywords: MPP +; LRPPRC variants; Parkinson's disease; Splicing; Minigene assay; MPP+;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Live imaging of mitochondrial dynamics in CNS dopaminergic neurons in vivo demonstrates early reversal of mitochondrial transport following MPP+ exposure

Keywords: MPP +; Parkinson's disease; Mitochondrial dynamics; MPP+;  Zebrafish; Live imaging

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

N-methyltetrahydropyridines and pyridinium cations as toxins and comparison with naturally-occurring alkaloids

Keywords: MPP +; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP); 1-methyl-4-phenylpyridinium cation (MPP+); Paraquat; β-carboline; Tetrahydroisoquinoline; Neurotoxins; Neuroprotectants; Parkinson's disease; BBB; blood-brain barrier; βCs; β-carbolines; βC+s; β-ca

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Effect of the pituitary adenylate cyclase-activating polypeptide on the autophagic activation observed in in vitro and in vivo models of Parkinson's disease

Keywords: MPP +; Akt; protein kinase B; Bcl-2; B-cell lymphoma 2 anti-apoptotic protein; DA; dopaminergic; DAPI; 2-(4-amidinophenyl)-1 H-indole-6-carboxamidine hydrochloride; FBS; fetal bovine serum; GFP; green fluorescent protein; JNK; c-Jun. N-terminal kinase; LC3 I an

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Deferoxamine-mediated up-regulation of HIF-1α prevents dopaminergic neuronal death via the activation of MAPK family proteins in MPTP-treated mice

Keywords: MPP +; α-Syn; α-Synuclein; AD; Alzheimer's disease; APP; amyloid precursor protein; BBB; blood-brain barrier; DAB; 3,3′-Diaminobenzidine tetrahydrochloride; DFO; deferoxamine; DMEM; Dulbecco's minimum essential medium; DMSO; dimethyl sulfoxide; DMT1; dival

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Pharmacological modulation of HDAC1 and HDAC6 in vivo in a zebrafish model: Therapeutic implications for Parkinson's disease

Keywords: MPP +; Abdil solution; antibody dilution solution; A.U.; arbitrary units; BBB; blood brain barrier; BSA; bovine serum albumin; DCPIP; 2,6-dichlorophenolindophenol; DD; deacetylase domain; dpf; days post fertilization; DMB; dynein motor binding; HAD; HDAC associa

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2016 سفارش ترجمه

Research articleThe A53E α-synuclein pathological mutation demonstrates reduced aggregation propensity in vitro and in cell culture

Keywords: MPP +; αS; α-synuclein; E. coli; Escherichia coli; EGFP; enhanced green fluorescent protein; K114; (trans,trans)-1-bromo-2,5-bis-(4-hydroxy)styrylbenzene; MPP+; MPP dihydrochloride hydrate; PBS; phosphate-buffered saline; PD; Parkinson's disease; SEM; standa

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

MTERF4 regulates the mitochondrial dysfunction induced by MPP+ in SH-SY5Y cells

Keywords: MPP +; Mitochondrial transcription termination factors 4 (MTERF4); mtDNA expression; Mitochondrial dysfunction; Parkinson's disease; MPP+;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Differential regulation of caspase-2 in MPP+-induced apoptosis in primary cortical neurons

Keywords: MPP +; PD; Parkinson׳s disease; MPTP; 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine; MPP+; 1-methyl-4-phenylpyridinium; MOMP; mitochondrial outer membrane permeabilization; PCD; programmed cell death pathway; Bax; Bcl-2 associated protein X; JNK; stress-activ

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

A tripeptide isolated from Bothrops atrox venom has neuroprotective and neurotrophic effects on a cellular model of Parkinson’s disease

Keywords: MPP +; Neuroprotection; Parkinson’s disease; Venom peptide; Bothrops atrox; Neuroplasticity; MPP+

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Basic neuroscienceA quantitative approach to developing Parkinsonian monkeys (Macaca fascicularis) with intracerebroventricular 1-methyl-4-phenylpyridinium injections

Keywords: MPP +; Parkinson's disease; Non-human primate animal model; Intracerebroventricular administration; MPP+; Dopaminergic cell loss; PD; Parkinson's disease; MPTP; 1-methyl-4-phenyl-1,2, 3,6-tetrahydropyridine; MPP+; 1-methyl-4-phenylpyridinium; i.c.v.; intracerebr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Anti-apoptotic effect of modified Chunsimyeolda-tang, a traditional Korean herbal formula, on MPTP-induced neuronal cell death in a Parkinson's disease mouse model

Keywords: MPP +; ABC; avidin-biotin peroxidase complex; DG; modified Chungsimyeolda-tang; FBS; fetal bovine serum; MYH; modified Youldahanso-tang; PD; Parkinson's disease; MEM; minimal essential medium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+; 1-methyl-4-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Neuroprotective effect of modified Chungsimyeolda-tang, a traditional Korean herbal formula, via autophagy induction in models of Parkinson׳s disease

Keywords: MPP +; DG; modified Chungsimyeolda-tang; MYH; modified Youldahanso-tang; SCM; Sasang Constitutional Medicine; PD; Parkinson׳s disease; UPS; ubiquitin-proteasome system; ALP; autophagy-lysosomal pathway; MPP+; 1-methyl-4-phenylpyridinium; NGF; nerve growth facto

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Functional characterization of the organic cation transporters (OCTs) in human airway pulmonary epithelial cells

Keywords: MPP +; ALI; air-liquid interface culture; EBSS; Earle's Balanced Salt Solution; MPP+; 1-methyl-4-phenylpyridinium; OCT; organic cation transporter; PBS; phosphate-buffered saline solution; PGE2; prostaglandine E2; TEER; transepithelial electrical resistance; P

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-7: A miRNA with expanding roles in development and disease

Keywords: MPP +; ACK1; activated CDC42 kinase 1; BASP1; brain abundant, membrane attached signal protein 1; c-Myc; v-Myc avian myelocytomatosis viral oncogene homolog; CD57; cluster of differentiation 57; CD44; cluster of differentiation 44; ciRS-7; circular RNA sponge fo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Research PaperProtective effects of Ndfip1 on MPP+-induced apoptosis in MES23.5 cells and its underlying mechanisms

Keywords: MPP +; Parkinson's disease; Ndfip1; Dopamine transporter; MPP+; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Attenuation of microglial RANTES by NEMO-binding domain peptide inhibits the infiltration of CD8+ T cells in the nigra of hemiparkinsonian monkey

Keywords: MPP +; DA; dopaminergic; ELISA; enzyme-linked immuno assay; IKK; IκB kinase; MPP+; 1-methyl-4-phenylpyridinium; NBD; NEMO-binding domain; NEMO; NF-κB essential modifier; RT-PCR; real-time polymerase chain reaction; TH; tyrosine hydroxylase; wt; wild type; Park

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Treadmill exercise activates Nrf2 antioxidant system to protect the nigrostriatal dopaminergic neurons from MPP+ toxicity

Keywords: MPP +; Treadmill exercise; Nrf2; γGCLC; HO-1; Parkinson's disease; Dopaminergic neurons; MPP+;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo

Keywords: MPP +; 6-OHDA; 6-hydroxydopamine; AAV; adeno-associated viral vector; Bcl-2; B-cell lymphoma 2; CNS; central nervous system; ctl; contralateral; DAPI; 4′,6-diamidino-2-phenylindole; DIV; day in vitro; DOPAC; 3,4-dihydroxyphenylacetic acid; EGFP; enhanced green

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-7 activates Nrf2 pathway by targeting Keap1 expression

Keywords: MPP +; ARE; antioxidant response elements; CNC; Cap 'n' Collar; CBA; coumarin boronic acid; GCLM; glutamate-cysteine ligase modifier subunit; eGFP; enhanced green fluorescent protein; HO-1; heme oxygenase 1; iTRAQ; Isobaric tags for relative and absolute qua

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2015 سفارش ترجمه

Neuroprotective effects of 5-(4-hydroxy-3-dimethoxybenzylidene)-thiazolidinone in MPTP induced Parkinsonism model in mice

Keywords: MPP +; 5-(4-hydroxy-3-dimethoxybenzylidene)-2-thioxo-4-thiazolidinone; Parkinson's disease; MPTP; MPP+; Mitochondrial dysfunction;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of the microglial response is essential for the neuroprotective effects of Rho-kinase inhibitors on MPTP-induced dopaminergic cell death

Keywords: MPP +; Dopamine; Neuroprotection; Neuroinflammation; Microglia; Parkinson; Rho; LME; l-leucine methyl ester; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-metil-4-fenil-1,2,3,6 tetrahidropiridine; PD; Parkinson's disease; ROCK; Rho-associated Kinase; TH; tyrosine h

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's disease

Keywords: MPP +; 4E-BP1; eukaryotic initiation factor 4E binding protein 1; 6-OHDA; 6-hydroxydopamine; ACC; acetyl-CoA carboxylase; AD; Alzheimer's disease; AMPK; AMP-dependent/activated protein kinase; DAB; 3,3′-diaminobenzidine tetrachloride; DAPI; 4′,6-diamidino-2-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Effects of the Parkinsonian toxin MPP+ on electrophysiological properties of nigral dopaminergic neurons

Keywords: MPP +; Dopamine; D2 autoreceptors; KATP channels; HCN channels; Brain slice; ACSF; artificial cerebrospinal fluid; ATP; adenosine triphosphate; DA; dopamine; DAT; dopamine transporter; GIRK; G protein-coupled inwardly rectifying potassium channels; HCN; hyperpol

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Puerarin protects dopaminergic neurons in Parkinson's disease models

Keywords: MPP +; MPP+; 1-methyl-4-pehenylpyridinium; 6-OHDA; 6-hydroxydopamine; BBB; blood-brain barrier; PD; Parkinson's disease; ROS; reactive oxygen species; SNc; substantia nigra compacta; TH; tyrosine hydroxylase; VMAT2; vesicular monoamine transporter 2; Parkins

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Primary cultured astrocytes from old rats are capable to activate the Nrf2 response against MPP+ toxicity after tBHQ pretreatment

Keywords: MPP +; Astrocytes; Primary cultures; Aging; Nrf2; tBHQ; MPP+; Oxidative stress; Antioxidant enzymes; GSH;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

PPARγ activation rescues mitochondrial function from inhibition of complex I and loss of PINK1

Keywords: MPP +; PD; Parkinson's disease; PPARγ; peroxisome proliferator-activated receptor gamma; TZDs; thiazolidinediones; RGS; Rosiglitazone; ΔΨm; Mitochondrial membrane potential; ROS; reactive oxygen species; PI; propidium Iodide; TMRM; Tetramethylrhodamine methyl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه