دانلود مقالات ISI درباره MPP + + ترجمه فارسی

Research ReportLipid-lowering drugs in the MPTP mouse model of Parkinson's disease: Fenofibrate has a neuroprotective effect, whereas bezafibrate and HMG-CoA reductase inhibitors do not

Keywords: MPP +; HMG-CoA; 3-hydroxy 3-methyl glutaryl co-enzyme A; MAO; monoamine oxidase; MPP+; 1-methyl-4-phenyl pyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; PPAR; peroxisome proliferator-activated receptor; ROS; reactive oxyg

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Cortical regulation of dopamine depletion-induced dendritic spine loss in striatal medium spiny neurons

Keywords: MPP +; cortex; dendrite; glutamate; MPP+; Parkinson’s disease; striatumDIV, days in vitro; HVA, homovanillic acid; ir, immunoreactive; MPP+, 1-methyl-4-phenylpyridinium; MSN, medium spiny neuron; PD, Parkinson’s disease; TBS, Tris-buffered saline; TBS+, 50 mM Tr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease

Keywords: MPP +; Echinacoside; Parkinson's disease; MPTP; MPP+; Apoptosis; Caspase-3; Caspase-8

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Interaction between nicotine and MPTP/MPP+ in rat brain endothelial cells

Keywords: MPP +; ARBEC; BBB; MPP+; MPTP; Nicotine; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Gene expression profiling of MPP+-treated MN9D cells: A mechanism of toxicity study

Keywords: MPP +; MPP+; MN9D cells; Microarray; Gene expression; Neurotoxicity; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Implication of PTEN in production of reactive oxygen species and neuronal death in in vitro models of stroke and Parkinson's disease

Keywords: MPP +; PTEN; ROS; Neuronal death; MPP+; OGD; SH-SY5Y; Rat primary hippocampal culture

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Neuroprotection by estrogen against MPP+-induced dopamine neuron death is mediated by ERα in primary cultures of mouse mesencephalon

Keywords: MPP +; Estrogen; Estrogen receptor; Neuroprotection; MPP+; Mesencephalon; Dopamine neuron; Astrocytes

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Comparative analysis of the effects of resveratrol in two apoptotic models: Inhibition of complex I and potassium deprivation in cerebellar neurons

Keywords: MPP +; cerebellar granule cells; resveratrol; sirtinol; SIRT1; MPP+; serum and potassium withdrawalCGN, cerebellar granule neuron; Ct, cycle threshold; H2DCFDA, 2,7-dichlorodihydrofluorescein diacetate; MPP+, 1-methyl-4-phenylpyridinium; PBS, phosphate buffered

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Leptin inhibits 1-methyl-4-phenylpyridinium-induced cell death in SH-SY5Y cells

Keywords: MPP +; Leptin; MPP+; Cytoprotective effects; PI-3 kinase; Obesity;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Imidaprilat, an angiotensin-converting enzyme inhibitor exerts neuroprotective effect via decreasing dopamine efflux and hydroxyl radical generation induced by bisphenol A and MPP+ in rat striatum

Keywords: MPP +; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+; 1-methyl-4-phenylpyridinium ion; ACE; angiotensin-converting enzyme; HPLC; high-performance liquid chromatography; OH; hydroxyl free radical; 2,3-DHBA; 2,3-dihydroxybenzoic acid; DA; Dopamine; Angi

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

The role of tissue transglutaminase in 1-methyl-4-phenylpyridinium (MPP+)-induced toxicity in differentiated human SH-SY5Y neuroblastoma cells

Keywords: MPP +; MPP+; 1-methyl-4-phenylpyridinium ion; MPTP; 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine; PD; Parkinson's disease; R283; 1,3,dimethyl-2-[(2-oxopropyl) thio] imidazolium chloride; TG; transglutaminase; TG2; tissue transglutaminase; Parkinson's disease; MP

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Adiponectin protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity

Keywords: MPP +; MPP+; Parkinson’s disease; Adiponectin; ROS; SOD; Catalase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Statistical parametric mapping of immunopositive cell density

Keywords: MPP +; Cell count; Statistical parametric mapping; MPP+; MPTP; Microglia; Iba-1; Dopamine neuron; Substantia nigra

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Mice lacking alpha-synuclein are resistant to mitochondrial toxins

Keywords: MPP +; MPTP; Paraquat; 3-Nitropropionic acid; Malonate; MPP+; MPP+ levels; Vesicular uptake; DHBA

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Rats with unilateral median forebrain bundle, but not striatal or nigral, lesions by the neurotoxins MPP+ or rotenone display differential sensitivity to amphetamine and apomorphine

Keywords: MPP +; Circling behavior; Complex-I inhibitor; animal model; Drug screening; Dopamine receptor supersensitivity; Parkinson's disease; MPP+; 6-OHDA; Rotenone; Contralateral and ipsilateral rotations

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Acute intranigral homocysteine administration produces stereotypic behavioral changes and striatal dopamine depletion in Sprague-Dawley rats

Keywords: MPP +; AD; Alzheimer's disease; COMT; catechol-O-methyl transferase; DA; dopamine; DOPAC; 3,4-dihydroxyphenylacetic acid; 5-HIAA; 5-hydroxyindolecaetic acid; 5-HT; 5-hydroxytryptamine; HVA; homovanillic acid; l-DOPA; levodopa; MPP+; 1-methyl-4-phenylpyridinium;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

2,9-Dimethyl-β-carbolinium, a neurotoxin occurring in human brain, is a potent inducer of apoptosis as 1-methyl-4-phenylpyridinium

Keywords: MPP +; β-carboline; MPP+; endogenous neurotoxins; synthetic neurotoxins; neuro 2A; ratBC, β-carboline; CSF, cerebrospinal fluid; DA, dopamine; DAT, dopamine transporter; DCF, 2′,7′-dichlorofluorescein; DOPAC, dihydroxyphenylacetic acid; Em, emission; Ex, excitat

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Molecular mechanism of the neurotrophic effect of GDNF on DA neurons: role of protein kinase CK2

Keywords: MPP +; Glial cell line-derived neurotrophic factor; Protein kinase CK2; Substantia nigra; Striatum; Tyrosine hydroxylase; Dopamine; MPP+

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

Sulfiredoxin: a potential therapeutic agent?

Keywords: MPP +; Glutathione; Glutathionylation; Sulfiredoxin; Reactive oxygen/nitrogen species; Oxidative stress; GST; ALS; amylotrophic lateral sclerosis; ER; endoplasmic reticulum; FRDA; Friedrich's ataxia; Grx; glutaredoxin; GSH; glutathione; GSSG; glutathione disul

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

MPTP induces intranuclear rodlet formation in midbrain dopaminergic neurons

Keywords: MPP +; AD; Alzheimer's disease; β3-tubulin; class III beta tubulin; DAPI; 4′-6-Diamidino-2-phenylindole; GR; glucocorticoid receptor; INR; intranuclear rodlet; MPP+; 1-methyl-4-phenylpyridinium ion; MPTP−; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NII;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Heat shock proteins protect both MPP+ and paraquat neurotoxicity

Keywords: MPP +; MPP+; Paraquat; Neuroblasts; Heat shock proteins; Quercetin;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Autotoxicity, methylation and a road to the prevention of Parkinson's disease

Keywords: MPP +; MPP+; nicotinamide; NNMT; NAD; Parkinson's disease; xenobiotics; autotoxicity;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Interleukin-6 induces glutathione in hippocampal cells

Keywords: MPP +; BSA; bovine serum albumin; BSO; buthionine sulfoximine; CNS; central nervous system; DTNB; 5,5′-dithio-bis(2-nitrobenzoic acid); DMEM; Dulbecco's modified Eagle's medium; FCS; fetal calf serum; GSH; glutathione; GSSG; glutathione disulfide; GR; glutathi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Decrease in cytosolic phospholipase A2α mRNA levels by reactive oxygen species via MAP kinase pathways in PC12 cells: effects of dopaminergic neurotoxins

Keywords: MPP +; Phospholipase A2α expression; Hydrogen peroxide; TIQ; MPP+; Mitogen-activated protein kinase; Rat PC12 cells;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Promethazine protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity

Keywords: MPP +; Promethazine; MPTP; MPP+; Parkinson; Neuroprotection; Mitochondria; Permeability transition pore; Membrane potential; Complex I; Mice;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Synergistic effects of hydrogen peroxide and ethanol on cell viability loss in PC12 cells by increase in mitochondrial permeability transition

Keywords: MPP +; carboxy-PTIO; 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide; DCFH2-DA; 2′,7′-dichlorofluorescin diacetate; DiOC6(3); 3,3′-dihexyloxacarbocyanine iodide; DTNB; 5,5′-dithio-bis-(2-nitrobenzoic acid); Mn-TBAP; Mn(III) tetrakis(4-b

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Triptolide protects dopaminergic neurons from inflammation-mediated damage induced by lipopolysaccharide intranigral injection

Keywords: MPP +; 6-OHDA; 6-hydroxydopamine; CNS; central nervous system; COX-2; cyclooxygenase 2; CR3; complement receptor 3; DA; dopamine; DOPAC; dihydroxyphenylacetic acid; ELISA; enzyme-linked immunoadsordent assay; HPLC; high-performance liquid chromatography; IFN; in

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Salvianic acid A protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity

Keywords: MPP +; DCFH-DA; 2,7-dichlorofluorescein diacetate; DCF; dichlorofluorescein; FITC; fluorescein isothiocyanate; MMP; mitochondrial membrane potential; MPP+; 1-methyl-4-phenylpyridinium ion; MPT; mitochondrial permeability transition; PBS; phosphate-buffered salin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Inhibition of MPP+-induced mitochondrial damage and cell death by trifluoperazine and W-7 in PC12 cells

Keywords: MPP +; Trifluoperazine; W-7; MPP+; Mitochondrial membrane permeability; Apoptotic cell death; PC12 cells;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Differences in interactions with the dopamine transporter as revealed by diminishment of Na+ gradient and membrane potential: Dopamine versus other substrates

Keywords: MPP +; Dopamine transporter; Amphetamine; Binding; Sodium; Depolarization; Synaptosomes; CFT; 2β-carbomethoxy-3β-(4-fluorophenyl)tropane; DA; dopamine; DAT; dopamine transporter; GBR12783; 1-[2-(diphenyl-methoxyl)ethyl)-4-(3-phenyl-2-propenyl)piperazine; HEK-2

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Therapeutic role of coenzyme Q10 in Parkinson's disease

Keywords: MPP +; AIF; apoptosis-inducing factor; ATP; adenosine 5′ triphosphate; C. elegans; Caenorhabditis elegans; CoA; coenzyme A; ETC; electron transport chain; FADH2; flavin adenine dinucleotide; IAP; inhibitors of apoptosis proteins; MOMP; mitochondrial outer memb

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity

Keywords: MPP +; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+; 1-methyl-4-phenylpuridinium; HF; high fat; DIO; diet-induced obesity; MAP-2; microtubule-associated protein 2; TH; tyrosine hydroxylase; Mn-SOD; manganese superoxide dismutase; Cu-Zn-SOD; copper-

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Oxidative stress and inflammation in Parkinson's disease: is there a causal link?

Keywords: MPP +; CNS; central nervous system; COX-2; cyclooxygenase-2; DOPAC; dihydroxyphenylacetic acid; DOPALD; dihydroxyphenylacetaldehyde; eNOS; endothelial NOS; GSH; glutathione; HNE; 4-hydroxy-2,3-nonenal; IFN-γ; interferon-gamma; IL; interleukin; iNOS; inducible N

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Mutational screening and zebrafish functional analysis of GIGYF2 as a Parkinson-disease gene

Keywords: MPP +; Parkinson disease; PARK11; GIGYF2; Mutational screening; Zebrafish; Morpholino oligonucleotide; MPP+;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen

Keywords: MPP +; Brain; Mitochondria; Neuroprotection; Oxidative stress; Tamoxifen; CsA; cyclosporin A; ΔΨm; mitochondrial transmembrane potential; GSH; reduced glutathione; GSSG; oxidized glutathione; MPP+; 1-methyl-4-phenyl-pyridinium ion; MPT; mitochondrial permeabil

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Effects of creatine treatment on the survival of dopaminergic neurons in cultured fetal ventral mesencephalic tissue

Keywords: MPP +; creatine kinase; neuroprotection; Parkinson's disease; ventral mesencephalon; tyrosine hydroxylase; rat cell cultures; BB-CK; brain-specific cytosolic isoform of creatine kinase; CK; creatine kinase; DIV; day in vitro; DMEM; Dulbecco's modified Eagle

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

The Role of Phospholipid Methylation in 1-Methyl-4-Phenyl-Pyridinium Ion (MPP+)-Induced Neurotoxicity in PC12 Cells

Keywords: MPP +; Parkinson's disease; MPP+; Phospholipid methylation; PC12 cells; Lysophosphatidylcholine; S-Adenosylmethionine;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Inhibitory Effects of Cigarette Smoke on Glial Inducible Nitric Oxide Synthase and Lack of Protective Properties Against Oxidative Neurotoxins In Vitro

Keywords: MPP +; Parkinson's disease; Smoking; Cigarettes; MPP+; Nitric oxide; Monoamine oxidase;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

Role of peroxidases in Parkinson disease: a hypothesis

Keywords: MPP +; COX-1; cyclooxygenase-1; COX-2; cyclooxygenase-2; IFN-γ; interferon-γ; IL-1β; interleukin-β; LPS; lipopolysaccharide; MAO-B; monoamine oxidase B; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPDP; 1-methyl-4-phenyl-1,2-dihydropyridine; MPP+; 1-

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه

Measurement of mitochondrial respiration in permeabilized murine neuroblastoma (N-2α) cells, a simple and rapid in situ assay to investigate mitochondrial toxins

Keywords: MPP +; Mitochondria; Toxicity; MPTP; MPP+; Neurotoxins; Digitonin; N-2α cells;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2005 سفارش ترجمه

Sgk1, a cell survival response in neurodegenerative diseases

Keywords: MPP +; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ASA; acetylsalicylic acid; C; cytoplasmic fraction; DA; dopamine; DAT; dopamine transporter; DEPD; digital expression pattern display; DEX; dexamethasone; DIC; days in culture; DIG; digoxigenin;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2005 سفارش ترجمه

The role of α-synuclein in neurodegenerative diseases

Keywords: MPP +; αSp22; O-glycosylated α-synuclein; 6-OHDA; 6-hydroxydopamine; Aβ; β-amyloid; AD; Alzheimer's disease; A; adenine; Ala; alanine; ALS; amyotrophic lateral sclerosis; APP; amyloid precursor protein; AR-JP; autosomal recessive juvenile parkinsonism; BS3;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2005 سفارش ترجمه

Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism

Keywords: MPP +; DEP; diesel exhaust particles; PM; particulate matter; PD; Parkinson's disease; AD; Alzheimer's disease; ROS; reactive oxygen species; NO; nitric oxide; TNFα; tumor necrosis factor-alpha; TH; tyrosine hydroxylase; Aβ; beta-amyloid; LPS; lipopolysacharid

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2005 سفارش ترجمه

Oxidative stress in the brain: Novel cellular targets that govern survival during neurodegenerative disease

Keywords: MPP +; Aβ; β-amyloid; AD; Alzheimer's disease; AIF; apoptosis-inducing factor; ALS; amyotrophic lateral sclerosis; Apaf-1; apoptotic protease-activating factor; APC; adenomatous polyposis coli; APP; amyloid precursor protein; BrdU; bromodeoxyuridine; CARD; cas

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2005 سفارش ترجمه

Therapeutic potential of adenosine A2A receptor antagonists in Parkinson's disease

Keywords: MPP +; Adenosine A2A receptor; Caffeine; Dyskinesia; Neuroprotection; Parkinson's disease; Striatum; 6-OHDA; 6-hydroxydopamine; ACh; acetylcholine; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; APEC; 2-[(2-aminoethylamino)carbonylethyl-phenylethyl

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2005 سفارش ترجمه