دانلود مقالات ISI درباره MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine + ترجمه فارسی

Neuroprotective effects of rotigotine in the acute MPTP-lesioned mouse model of Parkinson's disease

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; DA, dopamine; DAT, dopamine transporter; FJ, FluoroJade; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson's disease; SD, standard deviation; SN, substantia nigraRotigotine; Dopamine agonist; Continuous administration; Striatum; Substantia

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Activation of the calpain/cdk5/p25 pathway in the girus cinguli in Parkinson's disease

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; PD, Parkinson's disease; CDKs, cyclin-dependent kinases; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MEF2, myocyte enhancer factor 2Parkinson's disease; cdk5; E2F-1; Cell cycle

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Cell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; BSA, bovine serum albumin; CDK, cyclin-dependent kinase; CyD1, cyclin D1; CyE, cyclin E; HD, Huntington's disease; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson's disease; PV

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Investigating the potential neuroprotective effects of statins on DNA damage in mouse striatum

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson’s disease; MAO, monoamine oxidase; H2O2, hydrogen peroxide; OH, hydroxyl radical; iNOS, inducible form of nitric oxide synthase; ddH2O, double distilled water; Eph-BS, electrophoresis buffe

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

MsrA knockout mouse exhibits abnormal behavior and brain dopamine levels

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; aCSF, artificial cerebrospinal fluid; AD, Alzheimer's disease; DA, dopamine; DAT, DA transporter; PD, Parkinson's disease; MetO, methionine sulfoxide; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Msr, methionine sulfoxide reductase; 6-OHDA, 6-hydro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

The role of dopamine transporter in selective toxicity of manganese and rotenone

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; DAT, dopamine transporter; DMT1, divalent metal transporter-1; ICP-AES, inductively coupled plasma atomic emission spectroscopy; MPP+, 1-methyl-4-phenylpyridinium ion; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PAGE, polyacrylamide gel electropho

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Resveratrol, a red wine polyphenol, protects dopaminergic neurons in MPTP-treated mice

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+, 1-methyl-4-phenylpyridinium ion; DOPAC, 3,4-dihydroxyphenylacetic acid; BSA, Bovine serum albumine; DAT, DA transporter; DA, Dopamine; HPLC-ED, High-performance liquid chromatography with electroch

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Neurotoxicity of MPTP to migrating neuroblasts: Studies in acute and subacute mouse models of Parkinson's disease

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; Dcx, doublecortin; MAO-B, type B monoamine oxidase; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson's disease; RMS, rostral migratory stream; SN, substantia nigra; SVZ, subventricular zone; TH, tyrosine hydroxylase; TUNEL, terminal deoxy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Microglial activation is not prevented by tacrolimus but dopamine neuron damage is reduced in a rat model of Parkinson's disease progression

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; AMPA, α-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate; ANOVA, analysis of variance; DA, dopamine; GABA, gamma-aminobutyric acid; GP, globus pallidus; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NFAT, nuclear factor of activated T-cells; NMDA, N-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson's disease

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 6-OHDA, 6-hydroxydopamine; BBB, blood–brain barrier; DA, dopamine; DAergic, dopaminergic; DDC, diethyldithiocarbamate; Fe–S, iron–sulfur; GSH, glutathione; MPP+, 1-methyl-4-phenylpyridinium; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NOS, nitric

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Inhibitors of c-Jun N-terminal kinases—JuNK no more?

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; CVB3, Coxsackievirus B3; HIV, Human immunodeficiency virus; JNKs, c-Jun N-terminal kinases; MAPKs, mitogen-activated protein kinases; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PARP-1, poly(ADP-ribose) polymerase-1; PDB, Protein DataBase; ROS, Re

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2008 سفارش ترجمه

The isolation of neural stem cells from the olfactory bulb of Parkinson's disease model

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; PD, Parkinson's disease; OB, olfactory bulb; EGFP, enhanced green fluorescent protein; ST, striatum; SVZ, subventricular zone; PBS, phosphate buffered saline; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; BrdU, 5-bromo-2-deoxyuridine; GL, glomerular

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Dopamine and cognitive control: The influence of spontaneous eyeblink rate, DRD4 exon III polymorphism and gender on flexibility in set-shifting

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; ADHD, attention-deficit hyperactivity disorder; D1, D2, D3, D4, D5, dopamine receptor subtypes; EBR, spontaneous eyeblink rate; GABA, gamma-aminobutyric acid; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PFC, prefrontal cortexDopamine; Cognitive co

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

17β-Estradiol reduces nitrotyrosine immunoreactivity and increases SOD1 and SOD2 immunoreactivity in nigral neurons in male mice following MPTP insult

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; DAB, 3,3′-diaminobenzidine tetrahydrochloride; E2, 17β-estradiol; -IR, immunoreactive; MPP+, 1-methyl-4-phenylpyridinium; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NT, nitrotyrosine; PBS, phosphate buffered saline; PD, Parkinson's disease; SEM,

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Rotigotine treatment partially protects from MPTP toxicity in a progressive macaque model of Parkinson's disease

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; CB, cerebellum; DA, dopamine; DAT, dopamine transporter; l-DOPA, L-3,4-dihydroxyphenylalanine, levedopa; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson's disease; PET, positron emission tomography; ROI, region of interest; SNc, Substant

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Complement 3-deficient mice are not protected against MPTP-induced dopaminergic neurotoxicity

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; C3, complement 3; DA, dopamine; DOPAC, 3,4-dihydroxyphenylacetic acid; HVA, homovanillic acid; LPS, lipopolysaccharide; MAC, membrane attach complex; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson's disease; SNpc, substantia nigra pars

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

The effects of serotoninergic, noradrenergic, cholinergic and dopaminergic drugs on vigilance states in MPTP-treated mice

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; 5-HT, serotonin; ACh, acetylcholine; DA, dopamine; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NA, noradrenaline; PD, Parkinson's disease; PS, paradoxical sleep; S/W, sleep/wakefulness; SWS, slow-wave sleep; GABA, gamma-amino butyric acid; i.p., i

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

CD4+ T cells from Copolymer-1 immunized mice protect dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; BDNF, brain derived neurotrophic factor; CNS, central nervous system; Cop-1, Copolymer 1; FCM, flow cytometric; GDNF, glial cell derived neurotrophic factor; HRP, horseradish peroxidase; IL, interleukin; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Fluoro-Jade® B staining as useful tool to identify activated microglia and astrocytes in a mouse transgenic model of Alzheimer's disease

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; AD, Alzheimer's disease; APP, amyloid peptide precursor; DAPI, 4′,6-diamidino-2-phenylindole dihydrochloride; GFAP, glial fibrillary acidic protein; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NeuN, neuronal nuclei antigen; PS1, presenilin 1; TUNE

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Tamoxifen protects male mice nigrostriatal dopamine against methamphetamine-induced toxicity

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; DA, dopamine; DAT, dopamine transporter; DOPAC, 3,4-dihydroxyphenylacetic acid; HVA, homovanillic acid; MA, methamphetamine; MAO, monoamine oxidase; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson's disease; PPE, preproenkephalin; SN, su

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Endogenous semicarbazide-sensitive amine oxidase (SSAO) inhibitor increases 1-methyl-4-phenylpyridinium ion (MPP+)-induced dopamine efflux by immobilization stress in rat striatum

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; IEF, isoelectric focusing; IMMO, immobilization stress; MAO, monoamine oxidase; MPP+, 1-methyl-4-phenylpyridinium ion; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; SSAO, semicarbazide-sensitive amine oxidaseSemicarbazide-sensitive amine oxidase (SS

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Tamoxifen protect against hydroxyl radical generation induced by phenelzine in rat striatum

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+, 1-methyl-4-phenylpyridinium ion; OH, hydroxyl radical; 2,3-DHBA, 2,3-dihydroxybenzoic acid; MAO, monoamine oxidase; SSAO, semicarbazide-sensitive amine oxidase; HPLC-EC, high-performance liquid chr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Protocatechuic acid from Alpinia oxyphylla against MPP+-induced neurotoxicity in PC12 cells

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; CAT, catalase; DMEM, Dulbecco’s modified Eagle’s medium; DMSO, dimethyl sulfoxide; FBS, fetal bovine serum; GSH-Px, glutathione peroxidase; MPP+, 1-methyl-4-phenylpyridinium ion; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MTT, 3-(4,5-dimethylthia

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

TRPC1 protects human SH-SY5Y cells against salsolinol-induced cytotoxicity by inhibiting apoptosis

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson's disease; MAOB, Monoamine oxidase B; AD, Alzheimer's disease; SOCE, Store-operated calcium entry; Cch, carbachol; Tg, thapsigarginSalsolinol; Carbachol; Thapsigargin; Apoptosis; Neuroprote

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

NOX1/NADPH oxidase negatively regulates nerve growth factor-induced neurite outgrowth

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; BDNF, brain-derived neurotrophic factor; DPI, diphenyleneiodonium; ERK, extracellular signal-regulated kinase; FBS, fetal bovine serum; HBSS, Hank's balanced salt solution; HS, horse serum; LY, LY294002; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Osteopontin expression in substantia nigra in MPTP-treated primates and in Parkinson's disease

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; HLA-DR, human leukocyte antigen-DR; iNOS, inducible nitric oxide synthase; IL, interleukin; LPS, lipopolysaccharide; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MSA, multiple system atrophy; NO, nitric oxide; OPN, osteopontin; PD, Parkinson's dise

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Comparative aromatic hydroxylation and N-demethylation of MPTP neurotoxin and its analogs, N-methylated β-carboline and isoquinoline alkaloids, by human cytochrome P450 2D6

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; P450 or CYP, cytochrome P450; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PTP, 4-phenyl-1,2,3,6-tetrahydropyridine; MPTP-OH, 4-(4′-hydroxyphenyl)-1-methyl-1,2,3,6-tetrahydropyridine; MPDP+, 1-methyl-4-phenyl-2,3-dihydropyridinium; MPP+, 1-methyl-4

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

The parkinsonism producing neurotoxin MPP+ affects microtubule dynamics by acting as a destabilising factor

Keywords: MPTP، 1-methyl-4-phenyl-1،2،3،6-tetrahydropyridine; DIC, differential interference contrast; MPP+, 1-methyl-4-phenylpyridinium; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson’s disease1-Methyl-4-phenylpyridinium; Microtubule; Dynamics; Cytoskeleton; Neurodegeneration; Parkinson’s disease

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه