Keywords: Osteosarcoma; Icaritin; Multidrug resistance; MDR1; MRP1;
مقالات ISI (ترجمه نشده)
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Keywords: ABC; ATP-binding cassette; AKT; V-Akt murine thymoma viral oncogene homolog; ALDH1; aldehyde dehydrogenase 1; AR; androgen receptor; Bad; Bcl-2-associated death promoter; Bak; Bcl-2 homologous antagonist killer; Bax; Bcl-2-associated X protein; Bcl-2; B-c
Keywords: AI; anaemia of inflammation; ARE; anti-oxidant responsive element; ATP; adenosine triphosphate; Bmp; bone morphogenetic protein; CD; cluster of differentiation; C/EBP; CCAAT enhancer-binding protein; CO; carbon monoxide; CREB; cyclic adenosine monophospha
Keywords: Mrp1; Multidrug resistance proteins 1; Mrp2; Multidrug resistance proteins 2; Mrp3; Multidrug resistance proteins 3; Mrp4; Multidrug resistance proteins 4; Abcg2; ATP-binding cassette sub-family G member 2; Mrp transporters; Abcg2; Rat liver; Development;
Keywords: ABC; ATP-binding cassette; BCRP/ABCG2; breast cancer resistance protein; Bz; benzoyl; FTC; fumitremorgin C; mBu; methyl isobutyl; LBE; lowest binding energies; MDR; multidrug resistance; MRP1; multidrug-resistance-associated protein 1; POP; polyoxypregnan
Keywords: Proadifen; Cisplatin; MRP1; MRP2; Glutathione; Survivin;
Keywords: 17β-HSD; 17-beta hydroxysteroid dehydrogenase; MLHI; MutL Ecoli homolog 1; 2,5-HD; 2,5-n-hexandione; MMPs; Matrix metalloproteinases; AHr; Aryl Hydrocarbon receptor; MRP1; Multi-drug Resistance protein 1; Akr1c; Aldo-keto reductase family; NF-κβ; Nucle
Keywords: NSCLC; ILK; Snail; MRP1; Immunohistochemistry; Western blot
Keywords: OS; oxidative stress; ROS; reactive oxygen species; CNS; central nervous system; PD; Parkinson's disease; AD; Alzheimer's disease; GSH; reduced glutathione; GST; glutathione transferase; GSSG; glutathione disulfide; SN; substantia nigra; BSO; L-buthionine
Keywords: ABC transporter; ATP-binding cassette transporter; CD; conjugated dienes; CDEPA; 2-chloro-N-(2,6-diethylphenyl)acetamide; CMEPA; 2-chloro-N-(2-methyl-6 ethylphenyl)acetamide; DEA; 2,6-diethylaniline; GSH; glutathion; GST; glutathione-S-transferase; LPO; l
LncRNA-MALAT1 contributes to the cisplatin-resistance of lung cancer by upregulating MRP1 and MDR1 via STAT3 activation
Keywords: MALAT1; MDR; MRP1; STAT3; NSCLC;
Resveratrol dimer trans-ε-viniferin prevents rotaviral diarrhea in mice by inhibition of the intestinal calcium-activated chloride channel
Keywords: CFTR; cystic fibrosis transmembrane conductance regulator; TV; trans-ε-viniferin; RV; r-2-viniferin; CaCC; calcium-activated chloride channel; YFP; yellow fluorescent protein; FRT; fischer rat thyroid; ANO1; anoctamin 1; ATP; adenosine triphosphate; PMMA
Hypericin affects cancer side populations via competitive inhibition of BCRP
Keywords: ABC transporters; ATP-binding cassette transporters; ALDH; aldehyde dehydrogenase; BCRP; breast carcinoma resistance protein; CDH1; cadherin 1 gene encoding E-cadherin; CSLCs; cancer stem-like cells; DEAB; N,N-diethylaminobenzaldehyde; EDTA; ethylenediami
Mesoporous silica nanoparticles for drug and gene delivery
Keywords: AO; acridine orange; APTES; 3-aminopropyltriethoxysilane; APTMS; amino propyl trimethoxysilane; BCL-2; B-cell lymphoma-2; BCS; Biopharmaceutical Classification System; Bio-TEM; biological transmission electron microscopy; C dots; Cornell dots; CMC; critic
Monoterpene indole alkaloid azine derivatives as MDR reversal agents
Keywords: ABC; ATP binding cassette; ABCB1; ATP binding cassette subfamily B member 1; ABCG2; ATP binding cassette subfamily G member 2; BCRP; breast cancer resistance protein; BHK-21; baby hamster kidney; CS; collateral sensitivity; FACS; fluorescence-activated ce
Design and synthesis of new potent N,N-bis(arylalkyl)piperazine derivatives as multidrug resistance (MDR) reversing agents
Keywords: MDR reversers; P-gp modulators; Piperazine derivatives; Chemosensitizers; Doxorubicin-resistant human erythroleukemia K562â¯cells (K562/DOX); Pirarubicin uptake; P-gp; P-glycoprotein; MRP1; Multidrug Resistance associated Protein 1; BCRP; Breast Cancer R
PI3K pathway in prostate cancer: All resistant roads lead to PI3K
Keywords: CRPC; castration-resistant prostate cancer; ADT; androgen deprivation therapy; PI3K; phosphoinositide 3-kinase; AR; androgen receptor; PTEN; phosphatase and tensin homologue deleted on chromosome 10; INPP4B; inositol polyphosphate 4-phosphatase type II; P
Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells
Keywords: 2-DG; 2-deoxyglucose; 3-MST; 3-mercaptopyruvate sulfurtransferase; 5-FU; 5-fluorouracil; AA; antimycin A; ABC; ATP-binding cassette; AMPK; AMP kinase; AOAA; aminooxyacetic acid; ATM; ataxia-telangiectasia mutated serine/threonine protein kinase; ATP; aden
BCRP/ABCG2 and high-alert medications: Biochemical, pharmacokinetic, pharmacogenetic, and clinical implications
Keywords: ABC; ATP-binding cassette; AUC; area under the time-concentration curve; BCRP; breast cancer resistance protein; Cmax; maximum concentration; CYP; cytochrome P450; DOAC; direct oral anti-coagulant; GI; gastrointestinal; MRP1; multidrug resistance protei
Synthesis, structural characterization and biological activity of novel Knoevenagel condensates on DLD-1 human colon carcinoma
Keywords: ABTS; 2,2â²-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid); DPPH; di(phenyl)-(2,4,6-trinitrophenyl)iminoazanium; MDR1; multidrug resistance gene 1; MRP1; multidrug resistance-associated protein 1; PBS; Phosphate-buffered saline; SOD; superoxide dismu
Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation
Keywords: MRP1; ABCC1; Protein interactions; Tubulin; Linker 1 domain; Phosphorylation;
In this issueExpression of MRP1 and ABCG2 is associated with adverse clinical outcomes of papillary thyroid carcinoma with a solid component
Keywords: Solid variant; Papillary thyroid carcinoma; Cancer stem cell; MRP1; ABCG2;
Exceptionally high UBE2C expression is a unique phenomenon in basal-like type breast cancer and is regulated by BRCA1
Keywords: UBE2C; ubiquitin-conjugating enzyme 2C; BBC; basal-like breast cancer; HR; hazard ratio; P-gp; P-glycoprotein; MRP1; multidrug resistance protein 1; BCRP; breast cancer resistance protein; SD; standard deviation; Breast cancer; UBE2C; BRCA1; Doxorubicin;
Identification, signaling, and functions of LTB4 receptors
Keywords: AA; arachidonic acid; CLDN4; claudin-4; COX; cyclooxygenase; DGS3; desmoglein-3; DSS; dextran sodium sulfate; 5-LOX; 5-lipoxygenase; 5(S)-HETE; 5(S)-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid; 5(S)-HpETE; 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic a
Anticancer efficacy of p-dodecylaminophenol against high-risk and refractory neuroblastoma cells in vitro and in vivo
Keywords: 1; RA, all-trans retinoic acid; 2; 4-HPR, N-(4-hydroxyphenyl)retinamide, fenretinide; 3; p-DDAP, p-dodecylaminophenol, 4-(dodecylamino)phenol; 4; p-DAP, p-decylaminophenol, 4-(decylamino)phenol; 5; 4-HPDD, N-(4-hydroxyphenyl)dodecananamide, p-dodecanoylam
Anticancer activity of baicalein and luteolin studied in colorectal adenocarcinoma LoVo cells and in drug-resistant LoVo/Dx cells
Keywords: MDR; multidrug resistance; SRB; sulforhodamine B; siRNA; short interfering RNA; RNAi; RNA interference; Mdr1; multidrug resistance protein 1; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; MRP1; multidrug resistance associated protein 1; β
N-alkanol-N-cyclohexanol amine aryl esters: Multidrug resistance (MDR) reversing agents with high potency and efficacy
Keywords: MDR reversers; P-gp modulators; N-alkanol-N-cyclohexanol amine aryl esters; Chemosensitizers; Doxorubicin-resistant human erythroleukemia K562Â cells (K562/DOX); Pirarubicin uptake; P-gp; P-glycoprotein; BCRP; Breast Cancer Resistance Protein; MRP1; Multi
Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells
Keywords: ABC; ATP-binding cassette; ABCC; The ABC subfamily C; ABCC1; ATP-binding cassette subfamily C member 1; AHR; aryl hydrocarbon receptor; AKR1C1; aldo-keto reductase family 1 member C1; AREs; antioxidant-responsive elements; B-Raf; B-Raf proto-oncogene, ser
Regulation and control of nitric oxide (NO) in macrophages: Protecting the “professional killer cell” from its own cytotoxic arsenal via MRP1 and GSTP1
Keywords: Nitric oxide; Macrophages; MRP1;
Chaetominine reduces MRP1-mediated drug resistance via inhibiting PI3K/Akt/Nrf2 signaling pathway in K562/Adr human leukemia cells
Keywords: Chaetominine; Reversal effect; Chemoresistance; K562/Adr; MRP1;
Differential expression and response to arsenic stress of MRPs and ASAN1 determine sensitivity of classical multidrug-resistant leukemia cells to arsenic trioxide
Keywords: Arsenic-resistance; Multi-drug resistance; MRP1; MRP2; ASNA1; Leukemia cell;
β-carotene reverses multidrug resistant cancer cells by selectively modulating human P-glycoprotein function
Keywords: Multidrug resistant cancer; β-carotene; P-gp; Reversal effects; MDR; multidrug resistance; ABC; ATP-binding cassette; P-gp; P-glycoprotein; MRP1; multidrug resistance protein 1; BCRP; breast cancer resistance protein;
The role of PGC-1α and MRP1 in lead-induced mitochondrial toxicity in testicular Sertoli cells
Keywords: Lead acetate; Mitochondrial toxicity; Sertoli cell; PGC-1α; MRP1;
Cancer development, chemoresistance, epithelial to mesenchymal transition and stem cells: A snapshot of IL-6 mediated involvement
Keywords: Cytokine; IL-6; Cancer stem cell; Chemoresistance and EMT; MAPK; mitogen-activated protein kinases; STAT3; signal transducer and activator of transcription 3; gp130; glycoprotein 130; C/EBP; CCAAT/enhancer-binding protein; JAK; Janus kinase; PI3K; phospho
Nutrient restriction of glucose or serum results in similar proteomic expression changes in 3D colon cancer cell cultures
Keywords: Nutrient restriction; Three dimensional cell culture; Autophagy; Apoptosis; Quantitative proteomics; Colorectal cancer; NR; nutrient restriction; FBS; fetal bovine serum; iTRAQ; isobaric tags for relative and absolute quantification; SIRT1; sirtuin 1; PIA
Phenyltetrazolyl-phenylamides: Substituent impact on modulation capability and selectivity toward the efflux protein ABCG2 and investigation of interaction with the transporter
Keywords: ABC-transporter; ABCG2; BCRP inhibitor; Synthesis; Structure-activity relationship; Enzyme kinetics; ABC; ATP-binding cassette; BCRP; breast cancer resistance protein (ABCG2); CsA; cyclosporine A; FTC; fumitremorgin C; Imax; maximal inhibition; i-Pr; isop
MRP1 and P-glycoprotein expression assays would be useful in the additional detection of treatment non-responders in CML patients without ABL1 mutation
Keywords: RFI, ratio of mean fluorescence intensity; MRP1, multidrug resistance-associated protein-1; Pgp, P-glycoproteinChronic myelogenous leukemia; Multidrug resistance; MRP1; P-glycoprotein; Rhodamine-123 efflux assay
Cytotoxicity of medicinal plants of the West-Canadian Gwich׳in Native Americans towards sensitive and multidrug-resistant cancer cells
Keywords: MDR; multidrug resistance; ABC; ATP-binding cassette; MRP1; multidrug resistance related protein 1; BCRP; breast cancer resistance protein; MDR1; multidrug resistance gene 1 (P-glycoprotein); ABC transporter; Cancer; First nations; Multidrug resistance; P
Targeting glucosylceramide synthase induction of cell surface globotriaosylceramide (Gb3) in acquired cisplatin-resistance of lung cancer and malignant pleural mesothelioma cells
Keywords: Gb3; Globotriaosylceramide; GCS; Glucosylceramide synthase; GSL; Glycosphingolipid; MDR1; Multidrug resistance 1/P-glycoprotein; MPM; Malignant pleural mesothelioma (MPM); MRP1; Multidrug resistance-associated protein 1; NSCLC; Non-small cell lung cancer;
The role of Nrf2 in protection against Pb-induced oxidative stress and apoptosis in SH-SY5Y cells
Keywords: Lead; Neurotoxicity; Nrf2; Oxidative stress; Antioxidant gene; ARE; antioxidant response element; BSO; buthionine sulfoximine; DCFH-DA; 2â²7â²-dichlorodihydrofluorescein diacetate; DMSA; dimercaptosuccinic acid; DPI; diphenyliodonium chloride; EMSA; Ele
microRNA-7: A tumor suppressor miRNA with therapeutic potential
Keywords: ACK1; activated CDC42 kinase 1; Akt; V-Akt murine thymoma viral oncogene homolog; BCL-2; B-cell CLL/lymphoma 2; CCNE1; cyclin E1; ciRS-7; circular RNA sponge 7; c-Myc; V-Myc avian myelocytomatosis viral oncogene homolog; EGFR; epidermal growth factor rece
The accumulation and efflux of lead partly depend on ATP-dependent efflux pump-multidrug resistance protein 1 and glutathione in testis Sertoli cells
Keywords: Pb; lead; TM4; mouse testis Sertoli cells; Mrp1; multidrug resistance protein 1; TM4-sh; Mrp1lower-expression TM4 cells; ABC; ATP-binding cassette; GSH; glutathione; GST; glutathione-S-transferase; EA; ethacrvnic acid; BSO; Lbuthionine-sulfoximine; RT-q
MRP1 and GSTp1 expression in non-small cell lung cancer does not correlate with clinicopathological parameters: A Slovakian population study
Keywords: Lung cancer; MRP1; Glutathione-S-transferase p1; Immunohistochemistry;
DJ-1 mediates the resistance of cancer cells to dihydroartemisinin through reactive oxygen species removal
Keywords: ARTs; artemisinin and its derivatives; BCRP; breast cancer resistance protein; DCF-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DHA; dihydroartemisinin; DHE; dihydroethidine; 5-FU; 5-fluorouracil; GCLC; glutamate-cysteine ligase catalytic subunit
Wogonin reverses multi-drug resistance of human myelogenous leukemia K562/A02 cells via downregulation of MRP1 expression by inhibiting Nrf2/ARE signaling pathway
Keywords: Wogonin; Reversal effect; MRP1; DNA-PKcs; Nrf2/AREWogonin (PubChem CID: 5281703); DMSO (PubChem CID: 679); DAPI (PubChem CID: 2954); MTT formazan(PubChem CID: 16218671); Adriamycin (PubChem CID: 31703); H2O2 (PubChem CID: 784); tBHQ (PubChem CID: 16043)
Multidrug resistance (MDR) reversers: High activity and efficacy in a series of asymmetrical N,N-bis(alkanol)amine aryl esters
Keywords: MDR reversers; P-gp inhibitors; N,N-bis(alkanol)amine aryl esters; Chemosensitizers; Doxorubicin-resistant erythroleukemia K562 cells (K562/DOX); Pirarubicin uptake; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; MRP1; multidrug resistance-
Activity-lipophilicity relationship studies on P-gp ligands designed as simplified tariquidar bulky fragments
Keywords: Tariquidar; P-Glycoprotein; 2-Alkyloxyquinoline; Lipophilicity; BCRP; MRP1;
Potent and selective tariquidar bioisosters as potential PET radiotracers for imaging P-gp
Keywords: Arylthiazoles; P-glycoprotein (P-gp); MRP1; Tariquidar;
An isoquinoline alkaloid from the Chinese herbal plant Corydalis yanhusuo W.T. Wang inhibits P-glycoprotein and multidrug resistance-associate protein 1
Keywords: Corydalis yanhusuo W.T. Wang; Glaucine; Multidrug resistance; ABC transporters; P-gp; MRP1;
Relation between expression pattern of wild-type p53 and multidrug resistance proteins in human nephroblastomas
Keywords: Pgp/MDR1; MRP1; Wild-type p53; Nephroblastoma; Immunohistochemistry;