The antiepileptic drug lamotrigine is a substrate of mouse and human breast cancer resistance protein (ABCG2)
Keywords: Epilepsy; Pharmacoresistance; Transporter hypothesis; P-glycoprotein; AED; antiepileptic drug; AUC; area under curve; BBB; blood-brain barrier; BCRP/Bcrp; breast cancer resistance protein; CETA; concentration equilibrium transport assay; MDCK; Madin-Dar